Patrick W B Derksen (Patrick Wb Derksen, Patrick Derksen)

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 24

Top Topics

Breast Cancer Cells

Extracellular Matrix

Transforming Growth Factor

Top Venues

The Journal of cell biology

Journal of cell science

Nature communications

This page only lists publications with an associated author ORCID identifier.

Publications

Peter D Haughton, Wisse Haakma, Theofilos Chalkiadakis, Gerben E Breimer, Else Driehuis, Hans Clevers, Stefan Willems, Stefan Prekovic, Patrick W B Derksen
Differential transcriptional invasion signatures from patient derived organoid models define a functional prognostic tool for head and neck cancer. Oncogene 43 (32) (2024)
Antoine A Khalil, Daan Smits, Peter D Haughton, Thijs Koorman, Karin A Jansen, Mathijs P Verhagen, Mirjam van der Net, Kitty van Zwieten, Lotte Enserink, Lisa Jansen, Abdelrahman G El-Gammal, Daan Visser, Milena Pasolli, Max Tak, Denise Westland, Paul J van Diest, Cathy B Moelans, M Guy Roukens, Sandra Tavares, Anne-Marie N Fortier, Morag Park, Riccardo Fodde, Martijn Gloerich, Fried J T Zwartkruis, Patrick W B Derksen, Johan de Rooij
A YAP-centered mechanotransduction loop drives collective breast cancer cell invasion. Nature communications 15 (1) (2024)
Peter D Haughton, Wisse Haakma, Theofilos Chalkiadakis, Gerben E Breimer, Else Driehuis, Hans Clevers, Stefan Willems, Stefan Prekovic, Patrick W B Derksen
Differential transcriptional invasion signatures from patient derived organoid models define a functional prognostic tool for head and neck cancer. Oncogene 43 (32) (2024)
Peter D Haughton, Wisse Haakma, Theofilos Chalkiadakis, Gerben E Breimer, Else Driehuis, Hans Clevers, Stefan Willems, Stefan Prekovic, Patrick W B Derksen
Differential transcriptional invasion signatures from patient derived organoid models define a functional prognostic tool for head and neck cancer. Oncogene 43 (32) (2024)
Peter D Haughton, Wisse Haakma, Theofilos Chalkiadakis, Gerben E Breimer, Else Driehuis, Hans Clevers, Stefan Willems, Stefan Prekovic, Patrick W B Derksen
Differential transcriptional invasion signatures from patient derived organoid models define a functional prognostic tool for head and neck cancer. Oncogene (2024)
Antoine A Khalil, Daan Smits, Peter D Haughton, Thijs Koorman, Karin A Jansen, Mathijs P Verhagen, Mirjam van der Net, Kitty van Zwieten, Lotte Enserink, Lisa Jansen, Abdelrahman G El-Gammal, Daan Visser, Milena Pasolli, Max Tak, Denise Westland, Paul J van Diest, Cathy B Moelans, M Guy Roukens, Sandra Tavares, Anne-Marie N Fortier, Morag Park, Riccardo Fodde, Martijn Gloerich, Fried J T Zwartkruis, Patrick W B Derksen, Johan de Rooij
A YAP-centered mechanotransduction loop drives collective breast cancer cell invasion. Nature communications 15 (1) (2024)
Antoine A Khalil, Daan Smits, Peter D Haughton, Thijs Koorman, Karin A Jansen, Mathijs P Verhagen, Mirjam van der Net, Kitty van Zwieten, Lotte Enserink, Lisa Jansen, Abdelrahman G El-Gammal, Daan Visser, Milena Pasolli, Max Tak, Denise Westland, Paul J van Diest, Cathy B Moelans, M Guy Roukens, Sandra Tavares, Anne-Marie N Fortier, Morag Park, Riccardo Fodde, Martijn Gloerich, Fried J T Zwartkruis, Patrick W B Derksen, Johan de Rooij
A YAP-centered mechanotransduction loop drives collective breast cancer cell invasion. Nature communications 15 (1) (2024)
Lina M Gallego-Paez, William J S Edwards, Manasa V L Chanduri, Yanyu Guo, Thijs Koorman, Chieh-Yu Lee, Nina Grexa, Patrick W B Derksen, Jie Yan, Martin Alexander Schwartz, Jan Mauer, Benjamin Thomas Goult
TLN1 contains a cancer-associated cassette exon that alters talin-1 mechanosensitivity. The Journal of cell biology 222 (5) (2023)
Lilian M Sluimer, Esme Bullock, Max A K Rätze, Lotte Enserink, Celine Overbeeke, Marten Hornsveld, Valerie G Brunton, Patrick W B Derksen, Sandra Tavares
SKOR1 mediates FER kinase-dependent invasive growth of breast cancer cells. Journal of cell science 136 (3) (2023)
Zanetta Kechagia, Pablo Saez, Manuel Gómez-González, Brenda Canales, Srivatsava Viswanadha, Martín Zamarbide, Ion Andreu, Thijs Koorman, Amy E M Beedle, Alberto Elosegui-Artola, Patrick W B Derksen, Xavier Trepat, Marino Arroyo, Pere Roca-Cusachs
The laminin-keratin link shields the nucleus from mechanical deformation and signalling. Nature materials (2023)
Lilian M Sluimer, Esme Bullock, Max A K Rätze, Lotte Enserink, Celine Overbeeke, Marten Hornsveld, Valerie G Brunton, Patrick W B Derksen, Sandra Tavares
SKOR1 mediates FER kinase-dependent invasive growth of breast cancer cells. Journal of cell science 136 (3) (2023)
Lina M Gallego-Paez, William J S Edwards, Manasa V L Chanduri, Yanyu Guo, Thijs Koorman, Chieh-Yu Lee, Nina Grexa, Patrick W B Derksen, Jie Yan, Martin Alexander Schwartz, Jan Mauer, Benjamin Thomas Goult
TLN1 contains a cancer-associated cassette exon that alters talin-1 mechanosensitivity. The Journal of cell biology 222 (5) (2023)
Lina M Gallego-Paez, William J S Edwards, Manasa V L Chanduri, Yanyu Guo, Thijs Koorman, Chieh-Yu Lee, Nina Grexa, Patrick W B Derksen, Jie Yan, Martin Alexander Schwartz, Jan Mauer, Benjamin Thomas Goult
TLN1 contains a cancer-associated cassette exon that alters talin-1 mechanosensitivity. The Journal of cell biology 222 (5) (2023)
Lina M Gallego-Paez, William J S Edwards, Manasa V L Chanduri, Yanyu Guo, Thijs Koorman, Chieh-Yu Lee, Nina Grexa, Patrick W B Derksen, Jie Yan, Martin Alexander Schwartz, Jan Mauer, Benjamin Thomas Goult
TLN1 contains a cancer-associated cassette exon that alters talin-1 mechanosensitivity. The Journal of cell biology 222 (5) (2023)
Lina M Gallego-Paez, William J S Edwards, Manasa V L Chanduri, Yanyu Guo, Thijs Koorman, Chieh-Yu Lee, Nina Grexa, Patrick W B Derksen, Jie Yan, Martin Alexander Schwartz, Jan Mauer, Benjamin Thomas Goult
TLN1 contains a cancer-associated cassette exon that alters talin-1 mechanosensitivity. The Journal of cell biology 222 (5) (2023)
Lilian M Sluimer, Esme Bullock, Max A K Rätze, Lotte Enserink, Celine Overbeeke, Marten Hornsveld, Valerie G Brunton, Patrick W B Derksen, Sandra Tavares
SKOR1 mediates FER kinase-dependent invasive growth of breast cancer cells. Journal of cell science 136 (3) (2023)
Thijmen Sijnesael, François Richard, Max Ak Rätze, Thijs Koorman, Blessing Bassey-Archibong, Christa Rohof, Juliet Daniel, Christine Desmedt, Patrick W B Derksen
Canonical Kaiso target genes define a functional signature that associates with breast cancer survival and the invasive lobular carcinoma histological type. The Journal of pathology (2023)
Thijs Koorman, Karin A Jansen, Antoine A Khalil, Peter D Haughton, Daan Visser, Max A K Rätze, Wisse E Haakma, Gabrielè Sakalauskaitè, Paul J van Diest, Johan de Rooij, Patrick W B Derksen
Spatial collagen stiffening promotes collective breast cancer cell invasion by reinforcing extracellular matrix alignment. Oncogene 41 (17) (2022)
Max A K Rätze, Thijs Koorman, Thijmen Sijnesael, Blessing Bassey-Archibong, Robert van de Ven, Lotte Enserink, Daan Visser, Sridevi Jaksani, Ignacio Viciano, Elvira R M Bakker, François Richard, Andrew N J Tutt, Lynda O'Leary, Amanda Fitzpatrick, Pere Roca-Cusachs, Paul J van Diest, Christine Desmedt, Juliet M Daniel, Clare M Isacke, Patrick W B Derksen
Loss of E-cadherin leads to Id2-dependent inhibition of cell cycle progression in metastatic lobular breast cancer. Oncogene 41 (21) (2022)
Maxim De Schepper, Anne-Vincent Salomon, Matthias Christgen, Karen Van Baelen, François Richard, Hitoshi Tsuda, Sasagu Kurozumi, Maria Jose Brito, Gábor Cserni, Stuart J Schnitt, Denis Larsimont, Janina Kulka, Pedro Luis Fernandez, Paula Rodríguez-Martínez, Ana Aula Olivar, Cristina Melendez, Van Bockstal Mieke, Aniko Kovacs, Zsuzsanna Varga, Jelle Wesseling, Rohit Bhargava, Pia Boström, Camille Franchet, Blessing Zambuko, Gustavo Matute, Sophie Mueller, Anca Berghian, Emad Rakha, Paul J van Diest, Steffi Oesterreich, Patrick W B Derksen, Giuseppe Floris, Christine Desmedt
Results of a worldwide survey on the currently used histopathological diagnostic criteria for invasive lobular breast cancer. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 35 (12) (2022)
George Sflomos, Koen Schipper, Thijs Koorman, Amanda Fitzpatrick, Steffi Oesterreich, Adrian V Lee, Jos Jonkers, Valerie G Brunton, Matthias Christgen, Clare Isacke, Patrick W B Derksen, Cathrin Brisken
Atlas of Lobular Breast Cancer Models: Challenges and Strategic Directions. Cancers 13 (21) (2021)
Matthias Christgen, Stephan Bartels, Jana L van Luttikhuizen, Janin Bublitz, Luisa U Rieger, Henriette Christgen, Helge Stark, Bjoern Sander, Ulrich Lehmann, Doris Steinemann, Patrick W B Derksen, Hans Kreipe
E-cadherin to P-cadherin switching in lobular breast cancer with tubular elements. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 33 (12) (2020)
Jolien S de Groot, Max Ak Ratze, Miranda van Amersfoort, Tanja Eisemann, Eva J Vlug, Mijanou T Niklaas, Suet-Feung Chin, Carlos Caldas, Paul J van Diest, Jos Jonkers, Johan de Rooij, Patrick W B Derksen
αE-catenin is a candidate tumor suppressor for the development of E-cadherin-expressing lobular-type breast cancer. The Journal of pathology 245 (4) (2018)
Clara R L Oudenaarden, Robert A H van de Ven, Patrick W B Derksen
Re-inforcing the cell death army in the fight against breast cancer. Journal of cell science 131 (16) (2018)