Clare M Isacke (Clare Isacke)

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 18

Top Venues

British journal of cancer

Nature communications

Journal for immunotherapy of cancer

Cancer research

Institute of Cancer Research

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Institute of Cancer Research May 01 2001

United Kingdom

Professor of Molecular Cell Biology :: Division of Breast Cancer Research

Imperial College London Oct 01 1991 - Apr 30 2001

United Kingdom

Faculty :: Biology

Imperial College London Apr 01 1988 - Sep 30 1991

United Kingdom

Research Fellow :: Biochemistry

The Salk Institute Jan 20 1984 - Mar 31 1988

United States

Postdoctoral Fellow

Publications

John Alexander, Koen Schipper, Sarah Nash, Rachel Brough, Harriet Kemp, Jacopo Iacovacci, Clare M Isacke, Rachael Natrajan, Elinor J Sawyer, Christopher J Lord, Syed Haider
Pathway-based signatures predict patient outcome, chemotherapy benefit and synthetic lethal dependencies in invasive lobular breast cancer. British journal of cancer 130 (11) (2024)
Sarah L Ash, Rebecca Orha, Holly Mole, Meg Dinesh-Kumar, Steven P Lee, Frances K Turrell, Clare M Isacke
Targeting the activated microenvironment with endosialin (CD248)-directed CAR-T cells ablates perivascular cells to impair tumor growth and metastasis. Journal for immunotherapy of cancer 12 (2) (2024)
John Alexander, Koen Schipper, Sarah Nash, Rachel Brough, Harriet Kemp, Jacopo Iacovacci, Clare M Isacke, Rachael Natrajan, Elinor J Sawyer, Christopher J Lord, Syed Haider
Pathway-based signatures predict patient outcome, chemotherapy benefit and synthetic lethal dependencies in invasive lobular breast cancer. British journal of cancer 130 (11) (2024)
Sarah L Ash, Rebecca Orha, Holly Mole, Meg Dinesh-Kumar, Steven P Lee, Frances K Turrell, Clare M Isacke
Targeting the activated microenvironment with endosialin (CD248)-directed CAR-T cells ablates perivascular cells to impair tumor growth and metastasis. Journal for immunotherapy of cancer 12 (2) (2024)
John Alexander, Koen Schipper, Sarah Nash, Rachel Brough, Harriet Kemp, Jacopo Iacovacci, Clare M Isacke, Rachael Natrajan, Elinor J Sawyer, Christopher J Lord, Syed Haider
Pathway-based signatures predict patient outcome, chemotherapy benefit and synthetic lethal dependencies in invasive lobular breast cancer. British journal of cancer (2024)
John Alexander, Koen Schipper, Sarah Nash, Rachel Brough, Harriet Kemp, Jacopo Iacovacci, Clare M Isacke, Rachael Natrajan, Elinor J Sawyer, Christopher J Lord, Syed Haider
Pathway-based signatures predict patient outcome, chemotherapy benefit and synthetic lethal dependencies in invasive lobular breast cancer. British journal of cancer 130 (11) (2024)
Sarah L Ash, Rebecca Orha, Holly Mole, Meg Dinesh-Kumar, Steven P Lee, Frances K Turrell, Clare M Isacke
Targeting the activated microenvironment with endosialin (CD248)-directed CAR-T cells ablates perivascular cells to impair tumor growth and metastasis. Journal for immunotherapy of cancer 12 (2) (2024)
Amanda Fitzpatrick, Marjan Iravani, Adam Mills, David Vicente, Thanussuyah Alaguthurai, Ioannis Roxanis, Nicholas C Turner, Syed Haider, Andrew N J Tutt, Clare M Isacke
Genomic profiling and pre-clinical modelling of breast cancer leptomeningeal metastasis reveals acquisition of a lobular-like phenotype. Nature communications 14 (1) (2023)
Frances K Turrell, Rebecca Orha, Naomi J Guppy, Andrea Gillespie, Matthew Guelbert, Chris Starling, Syed Haider, Clare M Isacke
Age-associated microenvironmental changes highlight the role of PDGF-C in ER + breast cancer metastatic relapse. Nature cancer (2023)
Arany Soosainathan, Marjan Iravani, Rania El-Botty, John Alexander, Laura Sourd, Ludivine Morisset, Pierre Painsec, Rebecca Orha, Joanna Nikitorowicz-Buniak, Sunil Pancholi, Syed Haider, Mitchell Dowsett, Elisabetta Marangoni, Lesley-Ann Martin, Clare M Isacke
Targeting transcriptional regulation with a CDK9 inhibitor suppresses growth of endocrine- and palbociclib-resistant ER+ breast cancers. Cancer research (2023)
Liam Jenkins, Ute Jungwirth, Alexandra Avgustinova, Marjan Iravani, Adam Mills, Syed Haider, James Harper, Clare M Isacke
Cancer-Associated Fibroblasts Suppress CD8+ T-cell Infiltration and Confer Resistance to Immune-Checkpoint Blockade. Cancer research 82 (16) (2022)
Rachel J Evans, Douglas W Perkins, Joanna L Selfe, Anna Kelsey, Gavin P Birch, Janet M Shipley, Koen Schipper, Clare M Isacke
Endo180 (MRC2) antibody-drug conjugate for the treatment of sarcoma. Molecular cancer therapeutics (2022)
Amanda Fitzpatrick, Marjan Iravani, Adam Mills, Lucy Childs, Thanussuyah Alaguthurai, Angela Clifford, Isaac Garcia-Murillas, Steven Van Laere, Luc Dirix, Mark Harries, Alicia F C Okines, Nicholas C Turner, Syed Haider, Andrew N J Tutt, Clare M Isacke
Assessing CSF ctDNA to Improve Diagnostic Accuracy and Therapeutic Monitoring in Breast Cancer Leptomeningeal Metastasis. Clinical cancer research : an official journal of the American Association for Cancer Research 28 (6) (2022)
Max A K Rätze, Thijs Koorman, Thijmen Sijnesael, Blessing Bassey-Archibong, Robert van de Ven, Lotte Enserink, Daan Visser, Sridevi Jaksani, Ignacio Viciano, Elvira R M Bakker, François Richard, Andrew N J Tutt, Lynda O'Leary, Amanda Fitzpatrick, Pere Roca-Cusachs, Paul J van Diest, Christine Desmedt, Juliet M Daniel, Clare M Isacke, Patrick W B Derksen
Loss of E-cadherin leads to Id2-dependent inhibition of cell cycle progression in metastatic lobular breast cancer. Oncogene 41 (21) (2022)
Ute Jungwirth, Antoinette van Weverwijk, Rachel J Evans, Liam Jenkins, David Vicente, John Alexander, Qiong Gao, Syed Haider, Marjan Iravani, Clare M Isacke
Impairment of a distinct cancer-associated fibroblast population limits tumour growth and metastasis. Nature communications 12 (1) (2021)
Magdalena Kijewska, Carmen Viski, Frances Turrell, Amanda Fitzpatrick, Antoinette van Weverwijk, Qiong Gao, Marjan Iravani, Clare M Isacke
Using an in-vivo syngeneic spontaneous metastasis model identifies ID2 as a promoter of breast cancer colonisation in the brain. Breast cancer research : BCR 21 (1) (2019)
Antoinette van Weverwijk, Nikolaos Koundouros, Marjan Iravani, Matthew Ashenden, Qiong Gao, George Poulogiannis, Ute Jungwirth, Clare M Isacke
Metabolic adaptability in metastatic breast cancer by AKR1B10-dependent balancing of glycolysis and fatty acid oxidation. Nature communications 10 (1) (2019)
Ute Jungwirth, Antoinette van Weverwijk, Miriam J Melake, Ann F Chambers, Qiong Gao, Marc Fivaz, Clare M Isacke
Generation and characterisation of two D2A1 mammary cancer sublines to model spontaneous and experimental metastasis in a syngeneic BALB/c host. Disease models & mechanisms 11 (1) (2018)

Clare M Isacke.css-eqlu8i{font-size:small;padding-left:4px;} (Clare Isacke)

Publication Activity (10 Years)

Top Topics

Top Venues

Clare M Isacke (Clare Isacke)