Philippe Roche

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 14

Top Venues

Journal of medicinal chemistry

Nucleic acids research

ACS chemical biology

PLoS genetics

CNRS Délégation Provence et Corse

This page only lists publications with an associated author ORCID identifier.

Affiliation History

CNRS Délégation Provence et Corse Jan 03 2005

France

PI :: Cancer Research Center of Marseille

University of Oxford Sep 02 2001 - Feb 28 2005

United Kingdom

Visiting scientist :: Structural Biology

CNRS Délégation Midi-Pyrénées Oct 01 1992 - Feb 28 2005

France

Chargé de recherche :: Laboratoire des Interactions Plantes Microorganismes

University of Georgia Jul 01 1995 - Jan 09 1997

United States

Visiting Scientist :: Complex Carbohydrate Research Centre

Publications

Laurent Hoffer, Guillaume Charifi-Hoareau, Sarah Barelier, Stéphane Betzi, Thomas W Miller, Xavier Morelli, Philippe Roche
ChemoDOTS: a web server to design chemistry-driven focused libraries. Nucleic acids research (2024)
Laurent Hoffer, Guillaume Charifi-Hoareau, Sarah Barelier, Stéphane Betzi, Thomas W Miller, Xavier Morelli, Philippe Roche
ChemoDOTS: a web server to design chemistry-driven focused libraries. Nucleic acids research 52 (W1) (2024)
Laurent Hoffer, Guillaume Charifi-Hoareau, Sarah Barelier, Stéphane Betzi, Thomas W Miller, Xavier Morelli, Philippe Roche
ChemoDOTS: a web server to design chemistry-driven focused libraries. Nucleic acids research 52 (W1) (2024)
Laurent Hoffer, Manon Garcia, Raphael Leblanc, Mikael Feracci, Stéphane Betzi, Khaoula Ben Yaala, Avais M Daulat, Pascale Zimmermann, Philippe Roche, Karine Barral, Xavier Morelli
Discovery of a PDZ Domain Inhibitor Targeting the Syndecan/Syntenin Protein-Protein Interaction: A Semi-Automated "Hit Identification-to-Optimization" Approach. Journal of medicinal chemistry (2023)
Magali Saez-Ayala, Laurent Hoffer, Sébastien Abel, Khaoula Ben Yaala, Benoit Sicard, Guillaume P Andrieu, Mehdi Latiri, Emma K Davison, Marco A Ciufolini, Paul Brémond, Etienne Rebuffet, Philippe Roche, Carine Derviaux, Edwige Voisset, Camille Montersino, Remy Castellano, Yves Collette, Vahid Asnafi, Stéphane Betzi, Patrice Dubreuil, Sébastien Combes, Xavier Morelli
From a drug repositioning to a structure-based drug design approach to tackle acute lymphoblastic leukemia. Nature communications 14 (1) (2023)
Thomas Cuny, Pauline Romanet, Michelle Goldsworthy, Carole Guérin, Marie Wilkin, Philippe Roche, Frédéric A Sebag, Lynn E van Summeren, Mark Stevenson, Sarah A Howles, Jean Claude Deharo, Rajesh V Thakker, David Taïeb
Cinacalcet reverses short QT interval in Familial Hypocalciuric Hypercalcemia type 1. The Journal of clinical endocrinology and metabolism (2023)
Laetitia Ganier, Stéphane Betzi, Carine Derviaux, Philippe Roche, Charlotte Dessaux, Christophe Muller, Laurent Hoffer, Xavier Morelli, Jean-Paul Borg
Discovery of Small-Molecule Inhibitors of the PTK7/β-Catenin Interaction Targeting the Wnt Signaling Pathway in Colorectal Cancer. ACS chemical biology 17 (5) (2022)
Kendall Carrasco, Camille Montersino, Carine Derviaux, Magali Saez-Ayala, Laurent Hoffer, Audrey Restouin, Rémy Castellano, Justine Casassa, Philippe Roche, Eddy Pasquier, Sébastien Combes, Xavier Morelli, Yves Collette, Stéphane Betzi
CRCM5484: A BET-BDII Selective Compound with Differential Anti-leukemic Drug Modulation. Journal of medicinal chemistry 65 (7) (2022)
Nicolas Bosc, Christophe Muller, Laurent Hoffer, David Lagorce, Stéphane Bourg, Carine Derviaux, Marie-Edith Gourdel, Jean-Christophe Rain, Thomas W Miller, Bruno O Villoutreix, Maria A Miteva, Pascal Bonnet, Xavier Morelli, Olivier Sperandio, Philippe Roche
Fr-PPIChem: An Academic Compound Library Dedicated to Protein-Protein Interactions. ACS chemical biology 15 (6) (2020)
Laurent Hoffer, Magali Saez-Ayala, Dragos Horvath, Alexander Varnek, Xavier Morelli, Philippe Roche
CovaDOTS: In Silico Chemistry-Driven Tool to Design Covalent Inhibitors Using a Linking Strategy. Journal of chemical information and modeling 59 (4) (2019)
Annick Guiseppi, Juan Jesus Vicente, Julien Herrou, Deborah Byrne, Aurelie Barneoud, Audrey Moine, Leon Espinosa, Marie-Jeanne Basse, Virginie Molle, Tâm Mignot, Philippe Roche, Emillia M F Mauriello
A divergent CheW confers plasticity to nucleoid-associated chemosensory arrays. PLoS genetics 15 (12) (2019)
Laurent Hoffer, Christophe Muller, Philippe Roche, Xavier Morelli
Chemistry-driven Hit-to-lead Optimization Guided by Structure-based Approaches. Molecular informatics 37 (9-10) (2018)
Laurent Hoffer, Yuliia V Voitovich, Brigitt Raux, Kendall Carrasco, Christophe Muller, Aleksey Y Fedorov, Carine Derviaux, Agnès Amouric, Stéphane Betzi, Dragos Horvath, Alexander Varnek, Yves Collette, Sébastien Combes, Philippe Roche, Xavier Morelli
Integrated Strategy for Lead Optimization Based on Fragment Growing: The Diversity-Oriented-Target-Focused-Synthesis Approach. Journal of medicinal chemistry 61 (13) (2018)
Amandine Cartier-Michaud, Anne-Laure Bailly, Stéphane Betzi, Xiaoli Shi, Jean-Claude Lissitzky, Ana Zarubica, Arnauld Sergé, Philippe Roche, Adrien Lugari, Véronique Hamon, Florence Bardin, Carine Derviaux, Frédérique Lembo, Stephane Audebert, Sylvie Marchetto, Bénédicte Durand, Jean-Paul Borg, Ning Shi, Xavier Morelli, Michel A Aurrand-Lions
Genetic, structural, and chemical insights into the dual function of GRASP55 in germ cell Golgi remodeling and JAM-C polarized localization during spermatogenesis. PLoS genetics 13 (6) (2017)

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Publication Activity (10 Years)

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Philippe Roche