Ping-Long Xu (Pinglong Xu)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 42

Top Venues

Nature communications

Nature cell biology

The EMBO journal

Science advances

Zhejiang University

Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Zhejiang University Dec 01 2017

China

Qiushi Distinguished Professor :: Life Sciences Institute

Zhejiang University Jun 01 2013

China

Professor :: Life Sciences Institute

University of California San Francisco Jan 01 2011 - Mar 31 2013

United States

Assistant Research Cell Biologist :: Department of Cell and Tissue Biology

Education History

Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences Sep 01 1998 - Jul 31 2004

China

PHD :: Shanghai Institute of Biochemistry and Cell Biology

Sichuan University Sep 01 1994 - Jul 01 1998

China

BSC :: Department of Biology

Publications

Qirou Wu, Xiaohong Leng, Qian Zhang, Ye-Zhang Zhu, Ruyuan Zhou, Yutong Liu, Chen Mei, Dan Zhang, Shengduo Liu, Shasha Chen, Xiaojian Wang, Aifu Lin, Xia Lin, Jianpeng Sheng, Li Shen, Xin-Hua Feng, Bing Xia, Ping-Long Xu
IRF3 activates RB to authorize cGAS-STING-induced senescence and mitigate liver fibrosis. Science advances 10 (9) (2024)
Yuping Zheng, Ji Shun Chen, Vinitha Macwan, Charneal L Dixon, Xinran Li, Shengjie Liu, Yuyun Yu, Ping-Long Xu, Qiming Sun, Qi Hu, Wei Liu, Brian Raught, Gregory D Fairn, Dante Neculai
S-acylation of ATGL is required for lipid droplet homoeostasis in hepatocytes. Nature metabolism 6 (8) (2024)
Yutong Liu, Ailian Wang, Chen Chen, Qian Zhang, Qin Shen, Dan Zhang, Xueqi Xiao, Shasha Chen, Lili Lian, Zhenmin Le, Shengduo Liu, Tingbo Liang, Qinxiang Zheng, Ping-Long Xu, Jian Zou
Microglial cGAS-STING signaling underlies glaucoma pathogenesis. Proceedings of the National Academy of Sciences of the United States of America 121 (36) (2024)
Yingfeng Tu, Qin Yang, Min Tang, Li Gao, Yuanhao Wang, Jiuqiang Wang, Zhe Liu, Xiaoyu Li, Lejiao Mao, Rui Zhen Jia, Zhongwang Wang, Tie-Shan Tang, Ping-Long Xu, Yan Liu, Lunzhi Dai, Da Jia
TBC1D23 mediates Golgi-specific LKB1 signaling. Nature communications 15 (1) (2024)
Yingfeng Tu, Qin Yang, Min Tang, Li Gao, Yuanhao Wang, Jiuqiang Wang, Zhe Liu, Xiaoyu Li, Lejiao Mao, Rui Zhen Jia, Zhongwang Wang, Tie-Shan Tang, Ping-Long Xu, Yan Liu, Lunzhi Dai, Da Jia
TBC1D23 mediates Golgi-specific LKB1 signaling. Nature communications 15 (1) (2024)
Xinran Li, Cong Xiang, Shilei Zhu, Jiansheng Guo, Chang Liu, Ailian Wang, Jin Cao, Yan Lu, Dante Neculai, Ping-Long Xu, Xin-Hua Feng
SNX8 enables lysosome reformation and reverses lysosomal storage disorder. Nature communications 15 (1) (2024)
Ailian Wang, Chen Chen, Chen Mei, Shengduo Liu, Cong Xiang, Wen Fang, Fei Zhang, Yifan Xu, Shasha Chen, Qi Zhang, Xue-Li Bai, Aifu Lin, Dante Neculai, Bing Xia, Cunqi Ye, Jian Zou, Jianpeng Sheng, Xin-Hua Feng, Xinran Li, Chengyong Shen, Ping-Long Xu
Innate immune sensing of lysosomal dysfunction drives multiple lysosomal storage disorders. Nature cell biology 26 (2) (2024)
Xinran Li, Cong Xiang, Shilei Zhu, Jiansheng Guo, Chang Liu, Ailian Wang, Jin Cao, Yan Lu, Dante Neculai, Ping-Long Xu, Xin-Hua Feng
SNX8 enables lysosome reformation and reverses lysosomal storage disorder. Nature communications 15 (1) (2024)
Ailian Wang, Chen Chen, Chen Mei, Shengduo Liu, Cong Xiang, Wen Fang, Fei Zhang, Yifan Xu, Shasha Chen, Qi Zhang, Xue-Li Bai, Aifu Lin, Dante Neculai, Bing Xia, Cunqi Ye, Jian Zou, Jianpeng Sheng, Xin-Hua Feng, Xinran Li, Chengyong Shen, Ping-Long Xu
Innate immune sensing of lysosomal dysfunction drives multiple lysosomal storage disorders. Nature cell biology (2024)
Yutong Liu, Ailian Wang, Chen Chen, Qian Zhang, Qin Shen, Dan Zhang, Xueqi Xiao, Shasha Chen, Lili Lian, Zhenmin Le, Shengduo Liu, Tingbo Liang, Qinxiang Zheng, Ping-Long Xu, Jian Zou
Microglial cGAS-STING signaling underlies glaucoma pathogenesis. Proceedings of the National Academy of Sciences of the United States of America 121 (36) (2024)
Ruyuan Zhou, Mengqiu Wang, Xiao Li, Yutong Liu, Yihan Yao, Ailian Wang, Chen Chen, Qian Zhang, Qirou Wu, Qi Zhang, Dante Neculai, Bing Xia, Jian-Zhong Shao, Xin-Hua Feng, Tingbo Liang, Jian Zou, Xiaojian Wang, Ping-Long Xu
TBK1-Zyxin signaling controls tumor-associated macrophage recruitment to mitigate antitumor immunity. The EMBO journal (2024)
Qirou Wu, Xiaohong Leng, Qian Zhang, Ye-Zhang Zhu, Ruyuan Zhou, Yutong Liu, Chen Mei, Dan Zhang, Shengduo Liu, Shasha Chen, Xiaojian Wang, Aifu Lin, Xia Lin, Jianpeng Sheng, Li Shen, Xin-Hua Feng, Bing Xia, Ping-Long Xu
IRF3 activates RB to authorize cGAS-STING-induced senescence and mitigate liver fibrosis. Science advances 10 (9) (2024)
Yuping Zheng, Ji Shun Chen, Vinitha Macwan, Charneal L Dixon, Xinran Li, Shengjie Liu, Yuyun Yu, Ping-Long Xu, Qiming Sun, Qi Hu, Wei Liu, Brian Raught, Gregory D Fairn, Dante Neculai
S-acylation of ATGL is required for lipid droplet homoeostasis in hepatocytes. Nature metabolism 6 (8) (2024)
Yingfeng Tu, Qin Yang, Min Tang, Li Gao, Yuanhao Wang, Jiuqiang Wang, Zhe Liu, Xiaoyu Li, Lejiao Mao, Rui Zhen Jia, Zhongwang Wang, Tie-Shan Tang, Ping-Long Xu, Yan Liu, Lunzhi Dai, Da Jia
TBC1D23 mediates Golgi-specific LKB1 signaling. Nature communications 15 (1) (2024)
Yuping Zheng, Ji Shun Chen, Vinitha Macwan, Charneal L Dixon, Xinran Li, Shengjie Liu, Yuyun Yu, Ping-Long Xu, Qiming Sun, Qi Hu, Wei Liu, Brian Raught, Gregory D Fairn, Dante Neculai
S-acylation of ATGL is required for lipid droplet homoeostasis in hepatocytes. Nature metabolism (2024)
Ailian Wang, Chen Chen, Chen Mei, Shengduo Liu, Cong Xiang, Wen Fang, Fei Zhang, Yifan Xu, Shasha Chen, Qi Zhang, Xue-Li Bai, Aifu Lin, Dante Neculai, Bing Xia, Cunqi Ye, Jian Zou, Jianpeng Sheng, Xin-Hua Feng, Xinran Li, Chengyong Shen, Ping-Long Xu
Innate immune sensing of lysosomal dysfunction drives multiple lysosomal storage disorders. Nature cell biology 26 (2) (2024)
Ailian Wang, Chen Chen, Chen Mei, Shengduo Liu, Cong Xiang, Wen Fang, Fei Zhang, Yifan Xu, Shasha Chen, Qi Zhang, Xue-Li Bai, Aifu Lin, Dante Neculai, Bing Xia, Cunqi Ye, Jian Zou, Jianpeng Sheng, Xin-Hua Feng, Xinran Li, Chengyong Shen, Ping-Long Xu
Innate immune sensing of lysosomal dysfunction drives multiple lysosomal storage disorders. Nature cell biology 26 (2) (2024)
Bo Yuan, Jinquan Liu, Aiping Shi, Jin Cao, Yi Yu, Ye-Zhang Zhu, Chengbin Zhang, Yifei Qiu, Hongjie Luo, Jiaxian Shi, Xiaolei Cao, Ping-Long Xu, Li Shen, Tingbo Liang, Jonathan C Zhao, Xin-Hua Feng
HERC3 promotes YAP/TAZ stability and tumorigenesis independently of its ubiquitin ligase activity. The EMBO journal 42 (4) (2023)
Lijing Wang, Shuchen Gu, Fenfang Chen, Yi Yu, Jin Cao, Xinran Li, Chun Gao, Yanzhen Chen, Shuchong Yuan, Xia Liu, Jun Qin, Jonathan C Zhao, Ping-Long Xu, Jianpeng Sheng, Hong-Yan Tong, Xia Lin, Xin-Hua Feng
Imatinib blocks tyrosine phosphorylation of Smad4 and restores TGF-β growth-suppressive signaling in BCR-ABL1-positive leukemia. Signal transduction and targeted therapy 8 (1) (2023)
Bo Yuan, Jinquan Liu, Aiping Shi, Jin Cao, Yi Yu, Ye-Zhang Zhu, Chengbin Zhang, Yifei Qiu, Hongjie Luo, Jiaxian Shi, Xiaolei Cao, Ping-Long Xu, Li Shen, Tingbo Liang, Jonathan C Zhao, Xin-Hua Feng
HERC3 promotes YAP/TAZ stability and tumorigenesis independently of its ubiquitin ligase activity. The EMBO journal 42 (4) (2023)
Bo Yuan, Jinquan Liu, Aiping Shi, Jin Cao, Yi Yu, Ye-Zhang Zhu, Chengbin Zhang, Yifei Qiu, Hongjie Luo, Jiaxian Shi, Xiaolei Cao, Ping-Long Xu, Li Shen, Tingbo Liang, Jonathan C Zhao, Xin-Hua Feng
HERC3 promotes YAP/TAZ stability and tumorigenesis independently of its ubiquitin ligase activity. The EMBO journal 42 (4) (2023)
Miao Tian, Xiumei Wang, Jihong Sun, Wenlong Lin, Lumin Chen, Shengduo Liu, Ximei Wu, Liyun Shi, Ping-Long Xu, Xiujun Cai, Xiaojian Wang
Author Correction: IRF3 prevents colorectal tumorigenesis via inhibiting the nuclear translocation of β-catenin. Nature communications 14 (1) (2023)
Bo Yuan, Jinquan Liu, Aiping Shi, Jin Cao, Yi Yu, Ye-Zhang Zhu, Chengbin Zhang, Yifei Qiu, Hongjie Luo, Jiaxian Shi, Xiaolei Cao, Ping-Long Xu, Li Shen, Tingbo Liang, Jonathan C Zhao, Xin-Hua Feng
HERC3 promotes YAP/TAZ stability and tumorigenesis independently of its ubiquitin ligase activity. The EMBO journal 42 (4) (2023)
Bo Yuan, Jinquan Liu, Aiping Shi, Jin Cao, Yi Yu, Ye-Zhang Zhu, Chengbin Zhang, Yifei Qiu, Hongjie Luo, Jiaxian Shi, Xiaolei Cao, Ping-Long Xu, Li Shen, Tingbo Liang, Jonathan C Zhao, Xin-Hua Feng
HERC3 promotes YAP/TAZ stability and tumorigenesis independently of its ubiquitin ligase activity. The EMBO journal (2023)
Yifan Xu, Chen Chen, Zhiyong Liao, Ping-Long Xu
cGAS-STING signaling in cell death: Mechanisms of action and implications in pathologies. European journal of immunology (2023)
Dan Zhang, Yutong Liu, Yezhang Zhu, Qian Zhang, Hongxing Guan, Shengduo Liu, Shasha Chen, Chen Mei, Chen Chen, Zhiyong Liao, Ying Xi, Songying Ouyang, Xin-Hua Feng, Jianpeng Sheng, Li Shen, Ping-Long Xu
A non-canonical cGAS-STING-PERK pathway facilitates the translational program critical for senescence and organ fibrosis. Nature cell biology 24 (5) (2022)
Cheng-Yu Shi, Ying Wang, Minjie Wu, Yu Chen, Fangzhou Liu, Zheyuan Shen, Yiran Wang, Shaofang Xie, Yingying Shen, Ling-Jie Sang, Zhen Zhang, Zerui Gao, Luojia Yang, Lei Qu, Zuozhen Yang, Xinyu He, Yu Guo, Chenghao Pan, Jinxin Che, Huai-Qiang Ju, Jian Liu, Zhijian Cai, Qingfeng Yan, Luyang Yu, Liang-Jing Wang, Xiaowu Dong, Ping-Long Xu, Jian-Zhong Shao, Yang Liu, Xu Li, Wenqi Wang, Ruhong Zhou, Tianhua Zhou, Aifu Lin
Promoting anti-tumor immunity by targeting TMUB1 to modulate PD-L1 polyubiquitination and glycosylation. Nature communications 13 (1) (2022)
Chen Chen, Ping-Long Xu
Activation and Pharmacological Regulation of Inflammasomes. Biomolecules 12 (7) (2022)
Ruyuan Zhou, Qirou Wu, Mengqiu Wang, Seema Irani, Xiao Li, Qian Zhang, Fansen Meng, Shengduo Liu, Fei Zhang, Liming Wu, Xia Lin, Xiaojian Wang, Jian Zou, Hai Song, Jun Qin, Tingbo Liang, Xin-Hua Feng, Yan Jessie Zhang, Ping-Long Xu
The protein phosphatase PPM1A dephosphorylates and activates YAP to govern mammalian intestinal and liver regeneration. PLoS biology 19 (2) (2021)
Qingzhe Wu, Jingxin Guo, Yuning Liu, Qi Zheng, Xiaoling Li, Chuanqiang Wu, Dong Fang, Xin Chen, Liang Ma, Ping-Long Xu, Xiaofang Xu, Cheng Liao, Ming Wu, Li Shen, Hai Song
YAP drives fate conversion and chemoresistance of small cell lung cancer. Science advances 7 (40) (2021)
Jinquan Liu, Bo Yuan, Jin Cao, Hongjie Luo, Shuchen Gu, Mengdi Zhang, Ran Ding, Long Zhang, Fangfang Zhou, Mien-Chie Hung, Ping-Long Xu, Xia Lin, Jianping Jin, Xin-Hua Feng
AMBRA1 Promotes TGFβ Signaling via Nonproteolytic Polyubiquitylation of Smad4. Cancer research 81 (19) (2021)
Xin-Hua Feng, Jianhua Deng, Hanchenxi Zhang, Xinran Li, Shuchen Gu, Mingjie Zheng, Mei Tang, Yezhang Zhu, Xin Lin, Jianping Jin, Jisheng Liu, Jun Huang, Jian Zou, Zong-Ping Xia, Ping-Long Xu, Li Shen, Jonathan C Zhao
HSPA13 facilitates NF-κB-mediated transcription and attenuates cell death responses in TNFα signaling. Science advances 7 (41) (2021)
Yumei Hao, Yao Zhou, Yinhui Yu, Mingjie Zheng, Kechao Weng, Ziqi Kou, Jiancheng Liang, Qian Zhang, Xiajing Tang, Ping-Long Xu, Brian A Link, Ke Yao, Jian Zou
Interplay of MPP5a with Rab11 synergistically builds epithelial apical polarity and zonula adherens. Development (Cambridge, England) 147 (22) (2020)
Miao Tian, Xiumei Wang, Jihong Sun, Wenlong Lin, Lumin Chen, Shengduo Liu, Ximei Wu, Liyun Shi, Ping-Long Xu, Xiujun Cai, Xiaojian Wang
IRF3 prevents colorectal tumorigenesis via inhibiting the nuclear translocation of β-catenin. Nature communications 11 (1) (2020)
Chuantao Fang, Jian Li, Sixian Qi, Yubin Lei, Yan Zeng, Pengcheng Yu, Zhaolan Hu, Yufeng Zhou, Yulong Wang, Ruping Dai, Jin Li, Shenglin Huang, Ping-Long Xu, Kang Chen, Chen Ding, Fa-Xing Yu
An alternatively transcribed TAZ variant negatively regulates JAK-STAT signaling. EMBO reports 20 (6) (2019)
Bo Yuan, Jinquan Liu, Jin Cao, Yi Yu, Hanchenxi Zhang, Fei Wang, Yezhang Zhu, Mu Xiao, Sisi Liu, Youqiong Ye, Le Ma, Dewei Xu, Ningyi Xu, Yi Li, Jonathan C Zhao, Ping-Long Xu, Jianping Jin, Jianming Xu, Xi Chen, Li Shen, Xia Lin, Xin-Hua Feng
PTPN3 acts as a tumor suppressor and boosts TGF-β signaling independent of its phosphatase activity. The EMBO journal 38 (14) (2019)
Qianting Zhang, Mu Xiao, Shuchen Gu, Yongxian Xu, Ting Liu, Hao Li, Yi Yu, Lan Qin, Yezhang Zhu, Fenfang Chen, Yulong Wang, Chen Ding, Hongxing Wu, Hongbin Ji, Zhe Chen, Youli Zu, Stephen Malkoski, Yi Li, Tingbo Liang, Junfang Ji, Jun Qin, Ping-Long Xu, Bin Zhao, Li Shen, Xia Lin, Xin-Hua Feng
ALK phosphorylates SMAD4 on tyrosine to disable TGF-β tumour suppressor functions. Nature cell biology 21 (2) (2019)
Shiying Wu, Qian Zhang, Fei Zhang, Fansen Meng, Shengduo Liu, Ruyuan Zhou, Qingzhe Wu, Xinran Li, Li Shen, Jun Huang, Jun Qin, Songying Ouyang, Zong-Ping Xia, Hai Song, Xin-Hua Feng, Jian Zou, Ping-Long Xu
HER2 recruits AKT1 to disrupt STING signalling and suppress antiviral defence and antitumour immunity. Nature cell biology 21 (8) (2019)
Lin Hu, Jiafeng Xu, Xiaomei Xie, Yiwen Zhou, Panfeng Tao, Haidong Li, Xu Han, Chong Wang, Jian Liu, Ping-Long Xu, Dante Neculai, Zong-Ping Xia
Oligomerization-primed coiled-coil domain interaction with Ubc13 confers processivity to TRAF6 ubiquitin ligase activity. Nature communications 8 (1) (2017)
Qian Zhang, Fansen Meng, Shasha Chen, Steven W Plouffe, Shiying Wu, Shengduo Liu, Xinran Li, Ruyuan Zhou, Junxian Wang, Bin Zhao, Jianming Liu, Jun Qin, Jian Zou, Xin-Hua Feng, Kun-Liang Guan, Ping-Long Xu
Hippo signalling governs cytosolic nucleic acid sensing through YAP/TAZ-mediated TBK1 blockade. Nature cell biology 19 (4) (2017)
Weiwen Xiang, Qian Zhang, Xia Lin, Shiying Wu, Yao Zhou, Fansen Meng, Yunyun Fan, Tao Shen, Mu Xiao, Zongping Xia, Jian Zou, Xin-Hua Feng, Ping-Long Xu
PPM1A silences cytosolic RNA sensing and antiviral defense through direct dephosphorylation of MAVS and TBK1. Science advances 2 (7) (2016)
Fansen Meng, Ruyuan Zhou, Shiying Wu, Qian Zhang, Qiuheng Jin, Yao Zhou, Steven W Plouffe, Shengduo Liu, Hai Song, Zongping Xia, Bin Zhao, Sheng Ye, Xin-Hua Feng, Kun-Liang Guan, Jian Zou, Ping-Long Xu
Mst1 shuts off cytosolic antiviral defense through IRF3 phosphorylation. Genes & development 30 (9) (2016)

Ping-Long Xu.css-eqlu8i{font-size:small;padding-left:4px;} (Pinglong Xu)

Publication Activity (10 Years)

Top Topics

Top Venues

Ping-Long Xu (Pinglong Xu)