Gregory D Fairn

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 23

Top Venues

Nature communications

The Journal of cell biology

Nature metabolism

Nature cell biology

St. Michael's Hospital

Dalhousie University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

St. Michael's Hospital Jul 03 2012

Canada

Principal Investigator

Hospital for Sick Children Jan 07 2007 - Jun 30 2012

Canada

Post-doctoral fellow :: Cell Biology

Education History

Dalhousie University Sep 01 2001 - May 20 2007

Canada

PHD :: Biochemistry and Molecular Biology

Dalhousie University Sep 03 1996 - May 24 2001

Canada

BSC :: Biochemistry & Molecular Biology and Microbiology & Immunology

Publications

Yuping Zheng, Ji Shun Chen, Vinitha Macwan, Charneal L Dixon, Xinran Li, Shengjie Liu, Yuyun Yu, Ping-Long Xu, Qiming Sun, Qi Hu, Wei Liu, Brian Raught, Gregory D Fairn, Dante Neculai
S-acylation of ATGL is required for lipid droplet homoeostasis in hepatocytes. Nature metabolism 6 (8) (2024)
Yuping Zheng, Ji Shun Chen, Vinitha Macwan, Charneal L Dixon, Xinran Li, Shengjie Liu, Yuyun Yu, Ping-Long Xu, Qiming Sun, Qi Hu, Wei Liu, Brian Raught, Gregory D Fairn, Dante Neculai
S-acylation of ATGL is required for lipid droplet homoeostasis in hepatocytes. Nature metabolism 6 (8) (2024)
Yuping Zheng, Ji Shun Chen, Vinitha Macwan, Charneal L Dixon, Xinran Li, Shengjie Liu, Yuyun Yu, Ping-Long Xu, Qiming Sun, Qi Hu, Wei Liu, Brian Raught, Gregory D Fairn, Dante Neculai
S-acylation of ATGL is required for lipid droplet homoeostasis in hepatocytes. Nature metabolism (2024)
Michael G Sugiyama, Aidan I Brown, Jesus Vega-Lugo, Jazlyn P Borges, Andrew M Scott, Khuloud Jaqaman, Gregory D Fairn, Costin N Antonescu
Confinement of unliganded EGFR by tetraspanin nanodomains gates EGFR ligand binding and signaling. Nature communications 14 (1) (2023)
Michael G Sugiyama, Aidan I Brown, Jesus Vega-Lugo, Jazlyn P Borges, Andrew M Scott, Khuloud Jaqaman, Gregory D Fairn, Costin N Antonescu
Confinement of unliganded EGFR by tetraspanin nanodomains gates EGFR ligand binding and signaling. Nature communications 14 (1) (2023)
John Abousawan, Laura A Orofiamma, Gregory D Fairn, Costin N Antonescu
HER2 expression defines unique requirements for flotillin and c-Src for EGFR signaling. Journal of cell science (2023)
Michael G Sugiyama, Aidan I Brown, Jesus Vega-Lugo, Jazlyn P Borges, Andrew M Scott, Khuloud Jaqaman, Gregory D Fairn, Costin N Antonescu
Confinement of unliganded EGFR by tetraspanin nanodomains gates EGFR ligand binding and signaling. Nature communications 14 (1) (2023)
Charneal L Dixon, Noah R Martin, Micah J Niphakis, Benjamin F Cravatt, Gregory D Fairn
Attenuating ABHD17 enhances S- palmitoylation, membrane localization and signal transduction of NOD2 and Crohn's disease-associated variants. bioRxiv : the preprint server for biology (2023)
Rebecca Cabral-Dias, Stefanie Lucarelli, Karolina Zak, Sadia Rahmani, Gurjeet Judge, John Abousawan, Laura F DiGiovanni, Dafne Vural, Karen E Anderson, Michael G Sugiyama, Gizem Genc, Wanjin Hong, Roberto Jorge Botelho, Gregory D Fairn, Peter Kijun Kim, Costin N Antonescu
Fyn and TOM1L1 are recruited to clathrin-coated pits and regulate Akt signaling. The Journal of cell biology 221 (4) (2022)
Glenn F W Walpole, Jonathan Pacheco, Neha Chauhan, Jonathan Clark, Karen E Anderson, Yazan M Abbas, Danielle Brabant-Kirwan, Fernando Montaño-Rendón, Zetao Liu, Hongxian Zhu, John H Brumell, Alexander Deiters, Len R Stephens, Phillip T Hawkins, Gerald R V Hammond, Sergio Grinstein, Gregory D Fairn
Kinase-independent synthesis of 3-phosphorylated phosphoinositides by a phosphotransferase. Nature cell biology 24 (5) (2022)
Fernando Montaño-Rendón, Glenn F W Walpole, Matthias Krause, Gerald R V Hammond, Sergio Grinstein, Gregory D Fairn
PtdIns(3,4)P2, Lamellipodin, and VASP coordinate actin dynamics during phagocytosis in macrophages. The Journal of cell biology 221 (11) (2022)
Roni Levin-Konigsberg, Fernando Montaño-Rendón, Tal Keren-Kaplan, Ren Li, Braeden Ego, Sivakami Mylvaganam, Jessica E DiCiccio, William S Trimble, Michael C Bassik, Juan S Bonifacino, Gregory D Fairn, Sergio Grinstein
Phagolysosome resolution requires contacts with the endoplasmic reticulum and phosphatidylinositol-4-phosphate signalling. Nature cell biology 21 (10) (2019)
Yan Lu, Yuping Zheng, Etienne Coyaud, Chao Zhang, Apiraam Selvabaskaran, Yuyun Yu, Zizhen Xu, Xialian Weng, Ji Shun Chen, Ying Meng, Neil Warner, Xiawei Cheng, Yangyang Liu, Bingpeng Yao, Hu Hu, Zong-Ping Xia, Aleixo M Muise, Amira Klip, John H Brumell, Stephen E Girardin, Songmin Ying, Gregory D Fairn, Brian Raught, Qiming Sun, Dante Neculai
Palmitoylation of NOD1 and NOD2 is required for bacterial sensing. Science (New York, N.Y.) 366 (6464) (2019)
Yanbo Yang, Miriam Park, Masashi Maekawa, Gregory D Fairn
Enforced expression of phosphatidylinositol 4-phosphate 5-kinase homolog alters PtdIns(4,5)P2 distribution and the localization of small G-proteins. Scientific reports 9 (1) (2019)
Johannes Westman, Bernhard Hube, Gregory D Fairn
Integrity under stress: Host membrane remodelling and damage by fungal pathogens. Cellular microbiology 21 (4) (2019)
Takashi Hirama, Gregory D Fairn
Induction of spontaneous curvature and endocytosis: Unwanted consequences of cholesterol extraction using methyl-β-Cyclodextrin. Communicative & integrative biology 11 (2) (2018)
Stella M Lu, Gregory D Fairn
Mesoscale organization of domains in the plasma membrane - beyond the lipid raft. Critical reviews in biochemistry and molecular biology 53 (2) (2018)
Mira Sohn, Marek Korzeniowski, James P Zewe, Rachel C Wills, Gerald R V Hammond, Jana Humpolickova, Lukas Vrzal, Dominika Chalupska, Vaclav Veverka, Gregory D Fairn, Evzen Boura, Tamas Balla
PI(4,5)P2 controls plasma membrane PI4P and PS levels via ORP5/8 recruitment to ER-PM contact sites. The Journal of cell biology 217 (5) (2018)
Stella M Lu, Gregory D Fairn
7-Ketocholesterol impairs phagocytosis and efferocytosis via dysregulation of phosphatidylinositol 4,5-bisphosphate. Traffic (Copenhagen, Denmark) 19 (8) (2018)
Rong Hua, Derrick Cheng, Etienne Coyaud, Spencer Freeman, Erminia Di Pietro, Yuqing Wang, Adriano Vissa, Christopher M Yip, Gregory D Fairn, Nancy Braverman, John H Brumell, William S Trimble, Brian Raught, Peter Kijun Kim
VAPs and ACBD5 tether peroxisomes to the ER for peroxisome maintenance and lipid homeostasis. The Journal of cell biology 216 (2) (2017)
Liang Zhao, Chelsea L Thorsheim, Aae Suzuki, Timothy J Stalker, Sang H Min, Lurong Lian, Gregory D Fairn, Shamshad Cockcroft, Amy Durham, Sriram Krishnaswamy, Charles S Abrams
Phosphatidylinositol transfer protein-α in platelets is inconsequential for thrombosis yet is utilized for tumor metastasis. Nature communications 8 (1) (2017)
Takashi Hirama, Stella M Lu, Jason G Kay, Masashi Maekawa, Michael M Kozlov, Sergio Grinstein, Gregory D Fairn
Membrane curvature induced by proximity of anionic phospholipids can initiate endocytosis. Nature communications 8 (1) (2017)
Alaa Amash, Lin Wang, Yawen Wang, Varsha Bhakta, Gregory D Fairn, Ming Hou, Jun Peng, William P Sheffield, Alan H Lazarus
CD44 Antibody Inhibition of Macrophage Phagocytosis Targets Fcγ Receptor- and Complement Receptor 3-Dependent Mechanisms. Journal of immunology (Baltimore, Md. : 1950) 196 (8) (2016)

Gregory D Fairn.css-eqlu8i{font-size:small;padding-left:4px;}

Publication Activity (10 Years)

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Gregory D Fairn