Qing-Hua Hu (Qinghua Hu)

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 16

Top Topics

Ulcerative Colitis

Top Venues

Journal of medicinal chemistry

Nature communications

European heart journal

Molecular pharmaceutics

This page only lists publications with an associated author ORCID identifier.

Publications

Nanxia Zhang, Shige Shen, Mengyu Yang, Sijie He, Chunxiao Liu, Hongmei Li, Tao Lu, Haichun Liu, Qing-Hua Hu, Weifang Tang, Ya-Dong Chen
Design, Synthesis, and Biological Evaluation of a Novel NIK Inhibitor with Anti-Inflammatory and Hepatoprotective Effects for Sepsis Treatment. Journal of medicinal chemistry 67 (7) (2024)
Chunxiao Liu, Hui Wang, Lu Han, Yifan Zhu, Shurui Ni, Jingke Zhi, Xiping Yang, Jiayi Zhi, Tian Sheng, Huanqiu Li, Qing-Hua Hu
Targeting P2Y 14 R protects against necroptosis of intestinal epithelial cells through PKA/CREB/RIPK1 axis in ulcerative colitis. Nature communications 15 (1) (2024)
Yu-Hang Wang, Chun-Xiao Liu, Yi-Han Zhang, Ya-Lian Yang, Yan Zhao, Lu Han, Qian-Qian Wang, Wen Xiao, Qing-Hua Hu, Zhen-Hua Ding, Meng-Ze Zhou, Cheng Jiang
Discovery of a Series of 4-Amide-thiophene-2-carboxyl Derivatives as Highly Potent P2Y 14 Receptor Antagonists for Inflammatory Bowel Disease Treatment. Journal of medicinal chemistry 67 (14) (2024)
Nanxia Zhang, Shige Shen, Mengyu Yang, Sijie He, Chunxiao Liu, Hongmei Li, Tao Lu, Haichun Liu, Qing-Hua Hu, Weifang Tang, Ya-Dong Chen
Design, Synthesis, and Biological Evaluation of a Novel NIK Inhibitor with Anti-Inflammatory and Hepatoprotective Effects for Sepsis Treatment. Journal of medicinal chemistry 67 (7) (2024)
Yu-Hang Wang, Chun-Xiao Liu, Yi-Han Zhang, Ya-Lian Yang, Yan Zhao, Lu Han, Qian-Qian Wang, Wen Xiao, Qing-Hua Hu, Zhen-Hua Ding, Meng-Ze Zhou, Cheng Jiang
Discovery of a Series of 4-Amide-thiophene-2-carboxyl Derivatives as Highly Potent P2Y 14 Receptor Antagonists for Inflammatory Bowel Disease Treatment. Journal of medicinal chemistry 67 (14) (2024)
Nanxia Zhang, Shige Shen, Mengyu Yang, Sijie He, Chunxiao Liu, Hongmei Li, Tao Lu, Haichun Liu, Qing-Hua Hu, Weifang Tang, Ya-Dong Chen
Design, Synthesis, and Biological Evaluation of a Novel NIK Inhibitor with Anti-Inflammatory and Hepatoprotective Effects for Sepsis Treatment. Journal of medicinal chemistry (2024)
Chunxiao Liu, Hui Wang, Lu Han, Yifan Zhu, Shurui Ni, Jingke Zhi, Xiping Yang, Jiayi Zhi, Tian Sheng, Huanqiu Li, Qing-Hua Hu
Targeting P2Y 14 R protects against necroptosis of intestinal epithelial cells through PKA/CREB/RIPK1 axis in ulcerative colitis. Nature communications 15 (1) (2024)
Yu-Hang Wang, Chun-Xiao Liu, Yi-Han Zhang, Ya-Lian Yang, Yan Zhao, Lu Han, Qian-Qian Wang, Wen Xiao, Qing-Hua Hu, Zhen-Hua Ding, Meng-Ze Zhou, Cheng Jiang
Discovery of a Series of 4-Amide-thiophene-2-carboxyl Derivatives as Highly Potent P2Y 14 Receptor Antagonists for Inflammatory Bowel Disease Treatment. Journal of medicinal chemistry (2024)
Chunxiao Liu, Hui Wang, Lu Han, Yifan Zhu, Shurui Ni, Jingke Zhi, Xiping Yang, Jiayi Zhi, Tian Sheng, Huanqiu Li, Qing-Hua Hu
Targeting P2Y 14 R protects against necroptosis of intestinal epithelial cells through PKA/CREB/RIPK1 axis in ulcerative colitis. Nature communications 15 (1) (2024)
Yu-Hang Wang, Chun-Xiao Liu, Yi-Han Zhang, Ya-Lian Yang, Yan Zhao, Lu Han, Qian-Qian Wang, Wen Xiao, Qing-Hua Hu, Zhen-Hua Ding, Meng-Ze Zhou, Cheng Jiang
Discovery of a Series of 4-Amide-thiophene-2-carboxyl Derivatives as Highly Potent P2Y 14 Receptor Antagonists for Inflammatory Bowel Disease Treatment. Journal of medicinal chemistry 67 (14) (2024)
Chunxiao Liu, Hui Wang, Lu Han, Yifan Zhu, Shurui Ni, Jingke Zhi, Xiping Yang, Jiayi Zhi, Tian Sheng, Huanqiu Li, Qing-Hua Hu
Targeting P2Y 14 R protects against necroptosis of intestinal epithelial cells through PKA/CREB/RIPK1 axis in ulcerative colitis. Nature communications 15 (1) (2024)
Zhijie Wang, Li Yin, Zhenghan Xiong, Fei Huang, Na Yang, Fei Jiang, Huili Li, Yong Cui, Jiwei Ren, Zitian Cheng, Kun Jia, Tao Lu, Jiapeng Zhu, Qing-Hua Hu, Ya-Dong Chen
Discovery of a Bromodomain and Extra Terminal Domain (BET) Inhibitor with the Selectivity for the Second Bromodomain (BD2) and the Capacity for the Treatment of Inflammatory Diseases. Journal of medicinal chemistry (2023)
Yifan Zhu, Mengze Zhou, Xiangyu Cheng, Hui Wang, Yehong Li, Yueyue Guo, Yaxuan Wang, Sheng Tian, Tianqi Mao, Zhoudong Zhang, Duxin Li, Qing-Hua Hu, Huanqiu Li
Discovery of Selective P2Y 6 R Antagonists with High Affinity and In Vivo Efficacy for Inflammatory Disease Therapy. Journal of medicinal chemistry (2023)
Yehong Li, Mengze Zhou, Huanqiu Li, Chen Dai, Li Yin, Chunxiao Liu, Yuxin Li, Enming Zhang, Xinli Dong, Hui Ji, Qing-Hua Hu
Macrophage P2Y6 receptor deletion attenuates atherosclerosis by limiting foam cell formation through phospholipase Cβ/store-operated calcium entry/calreticulin/scavenger receptor A pathways. European heart journal (2023)
Yu-Hang Wang, Meng-Ze Zhou, Tao Ye, Ping-Ping Wang, Ran Lu, Yi-Lin Wang, Chun-Xiao Liu, Wen Xiao, Jia-Yi Li, Zi-Bo Meng, Li-Li Xu, Qing-Hua Hu, Cheng Jiang
Discovery of a Series of 5-Amide-1 H -pyrazole-3-carboxyl Derivatives as Potent P2Y 14 R Antagonists with Anti-Inflammatory Characters. Journal of medicinal chemistry 65 (23) (2022)
Shu-Min Ye, Meng-Ze Zhou, Wen-Jiao Jiang, Chun-Xiao Liu, Zhan-Wei Zhou, Min-Jie Sun, Qing-Hua Hu
Silencing of Gasdermin D by siRNA-Loaded PEI-Chol Lipopolymers Potently Relieves Acute Gouty Arthritis through Inhibiting Pyroptosis. Molecular pharmaceutics 18 (2) (2020)