Radek Jorda

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 19

Top Topics

Acute Myeloid Leukemia

Cell Cycle Arrest

Tyrosine Kinase

Endoplasmic Reticulum Stress

Top Venues

International journal of molecular sciences

Journal of medicinal chemistry

This page only lists publications with an associated author ORCID identifier.

Publications

Thalia Delgado, Denisa Veselá, Hana Dostálová, Vladimir Kryštof, Veronika Vojáčková, Radek Jorda, Alejandro Castro-Alvarez, Jeanluc Bertrand, Gildardo Rivera, Mario Faúndez, Miroslav Strnad, Christian Espinosa-Bustos, Cristian O Salas
New Inhibitors of Bcr-Abl Based on 2,6,9-Trisubstituted Purine Scaffold Elicit Cytotoxicity in Chronic Myeloid Leukemia-Derived Cell Lines Sensitive and Resistant to TKIs. Pharmaceutics 16 (5) (2024)
Thalia Delgado, Denisa Veselá, Hana Dostálová, Vladimir Kryštof, Veronika Vojáčková, Radek Jorda, Alejandro Castro-Alvarez, Jeanluc Bertrand, Gildardo Rivera, Mario Faúndez, Miroslav Strnad, Christian Espinosa-Bustos, Cristian O Salas
New Inhibitors of Bcr-Abl Based on 2,6,9-Trisubstituted Purine Scaffold Elicit Cytotoxicity in Chronic Myeloid Leukemia-Derived Cell Lines Sensitive and Resistant to TKIs. Pharmaceutics 16 (5) (2024)
Petra Břehová, Eva Řezníčková, Kryštof Škach, Radek Jorda, Milan Dejmek, Veronika Vojáčková, Michal Šála, Markéta Kovalová, Martin Dračínský, Alexandra Dolníková, Timotej Strmeň, Monika Kinnertová, Karel Chalupský, Alexandra Dvořáková, Tomáš Gucký, Helena Mertlíková Kaiserová, Pavel Klener, Radim Nencka, Vladimir Kryštof
Inhibition of FLT3-ITD Kinase in Acute Myeloid Leukemia by New Imidazo[1,2- b ]pyridazine Derivatives Identified by Scaffold Hopping. Journal of medicinal chemistry (2023)
Tânia Moreira, Domingos M Manuel, Joana Rosa, Rafael Santana Nunes, Veronika Vojáčková, Radek Jorda, Maria Conceiçao Oliveira, Nuno Manuel Xavier
Synthesis and Antiproliferative Evaluation of d-Glucuronamide-Based Nucleosides and (Triazolyl)methyl Amide-Linked Pseudodisaccharide Nucleosides. ChemMedChem (2023)
Monika Tomanová, Karolína Kozlanská, Radek Jorda, Lukáš Jedinák, Tereza Havlíková, Eva Řezníčková, Miroslav Peřina, Pavel Klener, Alexandra Dolníková, Petr Cankař, Vladimir Kryštof
Synthesis and Structural Optimization of 2,7,9-Trisubstituted purin-8-ones as FLT3-ITD Inhibitors. International journal of molecular sciences 23 (24) (2022)
Monika Tomanová, Karolína Kozlanská, Radek Jorda, Lukáš Jedinák, Tereza Havlíková, Eva Řezníčková, Miroslav Peřina, Pavel Klener, Alexandra Dolníková, Petr Cankař, Vladimir Kryštof
Synthesis and Structural Optimization of 2,7,9-Trisubstituted purin-8-ones as FLT3-ITD Inhibitors. International journal of molecular sciences 23 (24) (2022)
Jeanluc Bertrand, Hana Dostálová, Vladimir Kryštof, Radek Jorda, Thalía Delgado, Alejandro Castro-Alvarez, Jaime Mella-Raipán, David Cabezas, Mario Faúndez, Christian Espinosa-Bustos, Cristian O Salas
Design, Synthesis, In Silico Studies and Inhibitory Activity towards Bcr-Abl, BTK and FLT3-ITD of New 2,6,9-Trisubstituted Purine Derivatives as Potential Agents for the Treatment of Leukaemia. Pharmaceutics 14 (6) (2022)
Andreia Fortuna, Rita G Pereira, Paulo J Costa, Radek Jorda, Veronika Vojáčková, Gabriel Gonzalez, Niels V Heise, Rene Csuk, Maria Conceiçao Oliveira, Nuno Manuel Xavier
Synthesis and Exploitation of the Biological Profile of Novel Guanidino Xylofuranose Derivatives. ChemMedChem 17 (14) (2022)
Anton S Rudovich, Miroslav Peřina, Anastasiya V Krech, Maria Y Novozhilova, Anastasia M Tumilovich, Tatyana V Shkel, Irina P Grabovec, Miroslav Kvasnica, Lukáš Mada, Maria G Zavialova, Arif R Mekhtiev, Radek Jorda, Vladimir N Zhabinskii, Vladimir A Khripach
Synthesis and Biological Evaluation of New Isoxazolyl Steroids as Anti-Prostate Cancer Agents. International journal of molecular sciences 23 (21) (2022)
Monika Tomanová, Karolína Kozlanská, Radek Jorda, Lukáš Jedinák, Tereza Havlíková, Eva Řezníčková, Miroslav Peřina, Pavel Klener, Alexandra Dolníková, Petr Cankař, Vladimir Kryštof
Synthesis and Structural Optimization of 2,7,9-Trisubstituted purin-8-ones as FLT3-ITD Inhibitors. International journal of molecular sciences 23 (24) (2022)
Monika Tomanová, Karolína Kozlanská, Radek Jorda, Lukáš Jedinák, Tereza Havlíková, Eva Řezníčková, Miroslav Peřina, Pavel Klener, Alexandra Dolníková, Petr Cankař, Vladimir Kryštof
Synthesis and Structural Optimization of 2,7,9-Trisubstituted purin-8-ones as FLT3-ITD Inhibitors. International journal of molecular sciences 23 (24) (2022)
Radek Jorda, Libor Havlíček, Miroslav Peřina, Veronika Vojáčková, Tomáš Pospíšil, Stefan Djukic, Jana Škerlová, Jiri Gruz, Nicol Renešová, Pavel Klener, Pavlína Řezáčová, Miroslav Strnad, Vladimir Kryštof
3,5,7-Substituted Pyrazolo[4,3- d ]Pyrimidine Inhibitors of Cyclin-Dependent Kinases and Cyclin K Degraders. Journal of medicinal chemistry 65 (13) (2022)
Neetu Dayal, Eva Řezníčková, Delmis E Hernandez, Miroslav Peřina, Sandra Torregrosa-Allen, Bennett D Elzey, Jana Škerlová, Haresh Ajani, Stefan Djukic, Veronika Vojáčková, Martin Lepšík, Pavlína Řezáčová, Vladimir Kryštof, Radek Jorda, Herman O Sintim
3H-Pyrazolo[4,3-f]quinoline-Based Kinase Inhibitors Inhibit the Proliferation of Acute Myeloid Leukemia Cells In Vivo. Journal of medicinal chemistry 64 (15) (2021)
Denisa Hendrychová, Radek Jorda, Vladimir Kryštof
How selective are clinical CDK4/6 inhibitors? Medicinal research reviews 41 (3) (2020)
Monika Štětková, Kateřina Growková, Petr Fojtík, Barbora Valčíková, Veronika Palušová, Amandine Verlande, Radek Jorda, Vladimir Kryštof, Václav Hejret, Panagiotis Alexiou, Vladimír Rotrekl, Stjepan Uldrijan
CDK9 activity is critical for maintaining MDM4 overexpression in tumor cells. Cell death & disease 11 (9) (2020)
Cristian O Salas, Ana María Zarate, Vladimir Kryštof, Jaime Mella-Raipán, Mario Faundez, Jose Brea, María Isabel Loza, Ivan Brito, Denisa Hendrychová, Radek Jorda, Alan R Cabrera, Ricardo A Tapia, Christian Espinosa-Bustos
Promising 2,6,9-Trisubstituted Purine Derivatives for Anticancer Compounds: Synthesis, 3D-QSAR, and Preliminary Biological Assays. International journal of molecular sciences 21 (1) (2019)
Radek Jorda, Libor Havlíček, Antonín Šturc, Diana Tušková, Lenka Daumová, Mahmudul Alam, Jana Škerlová, Michaela Nekardová, Miroslav Peřina, Tomáš Pospíšil, Jitka Široká, Lubor Urbánek, Petr Pachl, Pavlína Řezáčová, Miroslav Strnad, Pavel Klener, Vladimir Kryštof
3,5,7-Substituted Pyrazolo[4,3- d]pyrimidine Inhibitors of Cyclin-Dependent Kinases and Their Evaluation in Lymphoma Models. Journal of medicinal chemistry 62 (9) (2019)
Radek Jorda, Denisa Hendrychová, Jiří Voller, Eva Řezníčková, Tomáš Gucký, Vladimir Kryštof
How Selective Are Pharmacological Inhibitors of Cell-Cycle-Regulating Cyclin-Dependent Kinases? Journal of medicinal chemistry 61 (20) (2018)
Radek Jorda, Susana M M Lopes, Eva Řezníčková, Vladimir Kryštof, Teresa M V D Pinho E Melo
Biological Evaluation of Dipyrromethanes in Cancer Cell Lines: Antiproliferative and Pro-apoptotic Properties. ChemMedChem 12 (9) (2017)