Rafael León

ResearcherID Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 16

Top Venues

Antioxidants (Basel, Switzerland)

The Journal of pharmacology and experimental therapeutics

Medicinal research reviews

Drug development research

Instituto de investigacion Sanitaria del Hospital Universitario La Princesa

Universidad Autónoma de Madrid (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Instituto de investigacion Sanitaria del Hospital Universitario La Princesa Jan 01 2012

Spain

Associate Researcher "Miguel Servet II" :: Servicio de Farmacología Clínica

Education History

Universidad Autónoma de Madrid Jul 06 2006

Spain

PHD :: Departamento de Química Orgánica

Publications

Marta Martínez-Casales, Raquel Hernanz, Zoe González-Carnicero, María T Barrús, Angela Martín, Ana M Briones, Patrycja Michalska, Rafael León, Estefano Pinilla, Ulf Simonsen, María J Alonso
The Melatonin Derivative ITH13001 Prevents Hypertension and Cardiovascular Alterations in Angiotensin II-Infused Mice. The Journal of pharmacology and experimental therapeutics 388 (2) (2024)
Paloma Mayo, Jorge Pascual-Guerra, Enrique Crisman, Cristina Domínguez, Manuela G López, Rafael León
Innovative pathological network-based multitarget approaches for Alzheimer's disease treatment. Medicinal research reviews (2024)
Marta Martínez-Casales, Raquel Hernanz, Zoe González-Carnicero, María T Barrús, Angela Martín, Ana M Briones, Patrycja Michalska, Rafael León, Estefano Pinilla, Ulf Simonsen, María J Alonso
The Melatonin Derivative ITH13001 Prevents Hypertension and Cardiovascular Alterations in Angiotensin II-Infused Mice. The Journal of pharmacology and experimental therapeutics 388 (2) (2024)
Marta Martínez-Casales, Raquel Hernanz, Zoe González-Carnicero, María T Barrús, Angela Martín, Ana M Briones, Patrycja Michalska, Rafael León, Estefano Pinilla, Ulf Simonsen, María J Alonso
The Melatonin Derivative ITH13001 Prevents Hypertension and Cardiovascular Alterations in Angiotensin II-Infused Mice. The Journal of pharmacology and experimental therapeutics 388 (2) (2024)
Marta Martínez-Casales, Raquel Hernanz, Zoe González-Carnicero, Maria T Barrús, Ángela Martin, Ana M Briones, Patrycja Michalska, Rafael León, Estéfano Pinilla, Ulf Simonsen, María J Alonso
The Melatonin Derivative ITH13001 Prevents Hypertension and Cardiovascular Alterations in Angiotensin II-Infused mice . The Journal of pharmacology and experimental therapeutics (2023)
Enrique Crisman, Pablo Duarte, Esteban Dauden, Antonio Cuadrado, María Isabel Rodríguez-Franco, Manuela G López, Rafael León
KEAP1-NRF2 protein-protein interaction inhibitors: Design, pharmacological properties and therapeutic potential. Medicinal research reviews 43 (1) (2022)
Pablo Duarte, Patrycja Michalska, Enrique Crisman, Antonio Cuadrado, Rafael León
Novel Series of Dual NRF2 Inducers and Selective MAO-B Inhibitors for the Treatment of Parkinson's Disease. Antioxidants (Basel, Switzerland) 11 (2) (2022)
Clara Herrera-Arozamena, Martín Estrada-Valencia, Patricia López-Caballero, Concepción Pérez, José A Morales-García, Ana Pérez-Castillo, Eric Del Sastre, Cristina Fernández-Mendívil, Pablo Duarte, Patrycja Michalska, José Lombardía, Sergio Senar, Rafael León, Manuela G López, María Isabel Rodríguez-Franco
Resveratrol-Based MTDLs to Stimulate Defensive and Regenerative Pathways and Block Early Events in Neurodegenerative Cascades. Journal of medicinal chemistry 65 (6) (2022)
Ángel Cores, Patrycja Michalska, José Miguel Pérez, Enrique Crisman, Clara Gómez, Mercedes Villacampa, José Carlos Menéndez, Rafael León
Enantioselective Synthesis and Pharmacological Evaluation of Aza-CGP37157-Lipoic Acid Hybrids for the Treatment of Alzheimer's Disease. Antioxidants (Basel, Switzerland) 11 (1) (2022)
Ángel Cores, Sheila Abril, Patrycja Michalska, Pablo Duarte, Ana I Olives, M Antonia Martín, Mercedes Villacampa, Rafael León, José Carlos Menéndez
Bisavenathramide Analogues as Nrf2 Inductors and Neuroprotectors in In Vitro Models of Oxidative Stress and Hyperphosphorylation. Antioxidants (Basel, Switzerland) 10 (6) (2021)
Víctor González-Ruiz, Ángel Cores, Olmo Martín-Cámara, Karen Orellana, Victor Cervera-Carrascon, Patrycja Michalska, Ana I Olives, Rafael León, M Antonia Martín, José Carlos Menéndez
Enhanced Stability and Bioactivity of Natural Anticancer Topoisomerase I Inhibitors through Cyclodextrin Complexation. Pharmaceutics 13 (10) (2021)
Ángel Cores, Noelia Carmona-Zafra, Olmo Martín-Cámara, Juan Domingo Sánchez, Pablo Duarte, Mercedes Villacampa, Paloma Bermejo-Bescós, Sagrario Martín-Aragón, Rafael León, José Carlos Menéndez
Curcumin-Piperlongumine Hybrids with a Multitarget Profile Elicit Neuroprotection in In Vitro Models of Oxidative Stress and Hyperphosphorylation. Antioxidants (Basel, Switzerland) 11 (1) (2021)
Patrycja Michalska, Paloma Mayo, Cristina Fernández-Mendívil, Giammarco Tenti, Pablo Duarte, Izaskun Buendia, María Teresa Ramos, Manuela G López, José Carlos Menéndez, Rafael León
Antioxidant, Anti-inflammatory and Neuroprotective Profiles of Novel 1,4-Dihydropyridine Derivatives for the Treatment of Alzheimer's Disease. Antioxidants (Basel, Switzerland) 9 (8) (2020)
Patrycja Michalska, Rafael León
When It Comes to an End: Oxidative Stress Crosstalk with Protein Aggregation and Neuroinflammation Induce Neurodegeneration. Antioxidants (Basel, Switzerland) 9 (8) (2020)
Patrycja Michalska, Giammarco Tenti, Michelle Satriani, Angel Cores, María Teresa Ramos, Antonio G García, José Carlos Menéndez, Rafael León
Aza-CGP37157-lipoic hybrids designed as novel Nrf2-inducers and antioxidants exert neuroprotection against oxidative stress and show neuroinflammation inhibitory properties. Drug development research 81 (3) (2019)
Izaskun Buendia, Giammarco Tenti, Patrycja Michalska, Iago Méndez-López, Enrique Luengo, Michelle Satriani, Juan-Fernando Padín, Manuela G López, M Teresa Ramos, Antonio G García, J Carlos Menéndez, Rafael León
Addition to "ITH14001, a CGP37157-Nimodipine Hybrid Designed to Regulate Calcium Homeostasis and Oxidative Stress, Exerts Neuroprotection in Cerebral Ischemia". ACS chemical neuroscience 8 (1) (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Rafael León