Roberto Zoncu

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 18

Top Topics

Fluorescent Probe

Endoplasmic Reticulum

Quality Control

Top Venues

Science advances

Science (New York, N.Y.)

Nature cell biology

Nature reviews. Molecular cell biology

This page only lists publications with an associated author ORCID identifier.

Publications

Nolwenn Samson, Cristina R Bosoi, Christian Roy, Laurie Turcotte, Laura Tribouillard, Mathilde Mouchiroud, Line Berthiaume, Jocelyn Trottier, Heitor C G Silva, Thomas Guerbette, Ana Belén Plata-Gómez, Aurèle Besse-Patin, Alicia Montoni, Nicolò Ilacqua, Jennifer Lamothe, Yemima R Citron, Yves Gélinas, Stéphane Gobeil, Roberto Zoncu, Alexandre Caron, Mathieu Morissette, Luca Pellegrini, Patrick J Rochette, Jennifer L Estall, Alejo Efeyan, Michael Shum, Étienne Audet-Walsh, Olivier Barbier, André Marette, Mathieu Laplante
HSDL2 links nutritional cues to bile acid and cholesterol homeostasis. Science advances 10 (22) (2024)
Nolwenn Samson, Cristina R Bosoi, Christian Roy, Laurie Turcotte, Laura Tribouillard, Mathilde Mouchiroud, Line Berthiaume, Jocelyn Trottier, Heitor C G Silva, Thomas Guerbette, Ana Belén Plata-Gómez, Aurèle Besse-Patin, Alicia Montoni, Nicolò Ilacqua, Jennifer Lamothe, Yemima R Citron, Yves Gélinas, Stéphane Gobeil, Roberto Zoncu, Alexandre Caron, Mathieu Morissette, Luca Pellegrini, Patrick J Rochette, Jennifer L Estall, Alejo Efeyan, Michael Shum, Étienne Audet-Walsh, Olivier Barbier, André Marette, Mathieu Laplante
HSDL2 links nutritional cues to bile acid and cholesterol homeostasis. Science advances 10 (22) (2024)
Claire Goul, Roberta Peruzzo, Roberto Zoncu
The molecular basis of nutrient sensing and signalling by mTORC1 in metabolism regulation and disease. Nature reviews. Molecular cell biology (2023)
Claire Goul, Roberta Peruzzo, Roberto Zoncu
Author Correction: The molecular basis of nutrient sensing and signalling by mTORC1 in metabolism regulation and disease. Nature reviews. Molecular cell biology (2023)
Hijai R Shin, Y Rose Citron, Lei Wang, Laura Tribouillard, Claire S Goul, Robin Stipp, Yusuke Sugasawa, Aakriti Jain, Nolwenn Samson, Chun-Yan Lim, Oliver B Davis, David Castaneda-Carpio, Mingxing Qian, Daniel K Nomura, Rushika M Perera, Eunyong Park, Douglas F Covey, Mathieu Laplante, Alex S Evers, Roberto Zoncu
Lysosomal GPCR-like protein LYCHOS signals cholesterol sufficiency to mTORC1. Science (New York, N.Y.) 377 (6612) (2022)
Rachel M Jansen, Roberta Peruzzo, Simon A Fromm, Adam L Yokom, Roberto Zoncu, James H Hurley
Structural basis for FLCN RagC GAP activation in MiT-TFE substrate-selective mTORC1 regulation. Science advances 8 (37) (2022)
Suprit Gupta, Julian Yano, Vincent Mercier, Htet Htwe Htwe, Hijai R Shin, Gilles Rademaker, Zeynep Cakir, Thomas Ituarte, Kwun W Wen, Grace E Kim, Roberto Zoncu, Aurélien Roux, David W Dawson, Rushika M Perera
Lysosomal retargeting of Myoferlin mitigates membrane stress to enable pancreatic cancer growth. Nature cell biology 23 (3) (2021)
Ryo Higuchi-Sanabria, Koning Shen, Naame Kelet, Phillip A Frankino, Jenni Durieux, Raz Bar-Ziv, Cierra N Sing, Enrique J Garcia, Stefan Homentcovschi, Melissa Sanchez, Rui Wu, Sarah U Tronnes, Larry Joe, Brant Webster, Alex Ahilon-Jeronimo, Samira Monshietehadi, Sofia Dallarda, Corinne L Pender, Liza A Pon, Roberto Zoncu, Andrew Dillin
Lysosomal recycling of amino acids affects ER quality control. Science advances 6 (26) (2020)
Christian Bindesbøll, Aleksander Aas, Margret Helga Ogmundsdottir, Serhiy Pankiv, Trine Reine, Roberto Zoncu, Anne Simonsen
NBEAL1 controls SREBP2 processing and cholesterol metabolism and is a susceptibility locus for coronary artery disease. Scientific reports 10 (1) (2020)
Ming-Yuan Su, Simon A Fromm, Roberto Zoncu, James H Hurley
Structure of the C9orf72 ARF GAP complex that is haploinsufficient in ALS and FTD. Nature 585 (7824) (2020)
Rosalie E Lawrence, Simon A Fromm, Yangxue Fu, Adam L Yokom, Do Jin Kim, Ashley M Thelen, Lindsey N Young, Chun-Yan Lim, Avi J Samelson, James H Hurley, Roberto Zoncu
Structural mechanism of a Rag GTPase activation checkpoint by the lysosomal folliculin complex. Science (New York, N.Y.) 366 (6468) (2019)
Rosalie E Lawrence, Roberto Zoncu
The lysosome as a cellular centre for signalling, metabolism and quality control. Nature cell biology 21 (2) (2019)
Chun-Yan Lim, Oliver B Davis, Hijai R Shin, Justin Zhang, Charles A Berdan, Xuntian Jiang, Jessica L Counihan, Daniel S Ory, Daniel K Nomura, Roberto Zoncu
ER-lysosome contacts enable cholesterol sensing by mTORC1 and drive aberrant growth signalling in Niemann-Pick type C. Nature cell biology 21 (10) (2019)
Clive Yik-Sham Chung, Hijai R Shin, Charles A Berdan, Breanna Ford, Carl C Ward, James A Olzmann, Roberto Zoncu, Daniel K Nomura
Covalent targeting of the vacuolar H+-ATPase activates autophagy via mTORC1 inhibition. Nature chemical biology 15 (8) (2019)
Y Rose Citron, Roberto Zoncu
Rhomboids Distort Time and Space: Accelerated Proteolysis through Membrane Disruption. Biochemistry 58 (16) (2019)
Chiara Di Malta, Diletta Siciliano, Alessia Calcagni, Jlenia Monfregola, Simona Punzi, Nunzia Pastore, Andrea N Eastes, Oliver B Davis, Rossella De Cegli, Angela Zampelli, Luca G Di Giovannantonio, Edoardo Nusco, Nick Platt, Alessandro Guida, Margret Helga Ogmundsdottir, Luisa Lanfrancone, Rushika M Perera, Roberto Zoncu, Pier Giuseppe Pelicci, Carmine Settembre, Andrea Balabio
Transcriptional activation of RagD GTPase controls mTORC1 and promotes cancer growth. Science (New York, N.Y.) 356 (6343) (2018)
Rosalie E Lawrence, Kelvin F Cho, Ronja Rappold, Anna Thrun, Marie Tofaute, Do Jin Kim, Ofer Moldavski, James H Hurley, Roberto Zoncu
A nutrient-induced affinity switch controls mTORC1 activation by its Rag GTPase-Ragulator lysosomal scaffold. Nature cell biology 20 (9) (2018)
Brian M Castellano, Ashley M Thelen, Ofer Moldavski, McKenna Feltes, Reini E N van der Welle, Laurel Mydock-McGrane, Xuntian Jiang, Robert J van Eijkeren, Oliver B Davis, Sharon M Louie, Rushika M Perera, Douglas F Covey, Daniel K Nomura, Daniel S Ory, Roberto Zoncu
Lysosomal cholesterol activates mTORC1 via an SLC38A9-Niemann-Pick C1 signaling complex. Science (New York, N.Y.) 355 (6331) (2017)