Rui Xiong

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 17

Top Topics

Respiratory Syndrome Coronavirus

Estrogen Receptor

Top Venues

Journal of medicinal chemistry

Pharmaceuticals (Basel, Switzerland)

Proceedings of the National Academy of Sciences of the United States of America

This page only lists publications with an associated author ORCID identifier.

Publications

Vishwesh Venkatraman, Jeremiah Gaiser, Daphne Demekas, Amitava Roy, Rui Xiong, Travis J Wheeler
Do Molecular Fingerprints Identify Diverse Active Drugs in Large-Scale Virtual Screening? (No). Pharmaceuticals (Basel, Switzerland) 17 (8) (2024)
Ganga Reddy Velma, Zhengnan Shen, Cameron Holberg, Jiqiang Fu, Farinaz Soleymani, Laura Cooper, Omar Lozano Ramos, Divakar Indukuri, Soumya Reddy Musku, Pavel Rychetsky, Steve Slilaty, Zuomei Li, Kiira Ratia, Lijun Rong, Dominik Schenten, Rui Xiong, Gregory R J Thatcher
Non-Covalent Inhibitors of SARS-CoV-2 Papain-Like Protease (PLpro): In Vitro and In Vivo Antiviral Activity. Journal of medicinal chemistry 67 (16) (2024)
Ganga Reddy Velma, Zhengnan Shen, Cameron Holberg, Jiqiang Fu, Farinaz Soleymani, Laura Cooper, Omar Lozano Ramos, Divakar Indukuri, Soumya Reddy Musku, Pavel Rychetsky, Steve Slilaty, Zuomei Li, Kiira Ratia, Lijun Rong, Dominik Schenten, Rui Xiong, Gregory R J Thatcher
Non-Covalent Inhibitors of SARS-CoV-2 Papain-Like Protease (PLpro): In Vitro and In Vivo Antiviral Activity. Journal of medicinal chemistry 67 (16) (2024)
Ganga Reddy Velma, Zhengnan Shen, Cameron Holberg, Jiqiang Fu, Farinaz Soleymani, Laura Cooper, Omar Lozano Ramos, Divakar Indukuri, Soumya Reddy Musku, Pavel Rychetsky, Steve Slilaty, Zuomei Li, Kiira Ratia, Lijun Rong, Dominik Schenten, Rui Xiong, Gregory R J Thatcher
Non-Covalent Inhibitors of SARS-CoV-2 Papain-Like Protease (PLpro): In Vitro and In Vivo Antiviral Activity. Journal of medicinal chemistry (2024)
Yangfeng Li, Zhengnan Shen, Kiira Ratia, Jiong Zhao, Fei Huang, Oleksii Dubrovyskyii, Divakar Indukuri, Jiqiang Fu, Omar Lozano Ramos, Gregory R J Thatcher, Rui Xiong
Structure-Guided Design and Synthesis of Pyridinone-Based Selective Bromodomain and Extra-Terminal Domain (BET)-First Bromodomain (BD1) Inhibitors. Journal of medicinal chemistry 67 (4) (2024)
Yangfeng Li, Zhengnan Shen, Kiira Ratia, Jiong Zhao, Fei Huang, Oleksii Dubrovyskyii, Divakar Indukuri, Jiqiang Fu, Omar Lozano Ramos, Gregory R J Thatcher, Rui Xiong
Structure-Guided Design and Synthesis of Pyridinone-Based Selective Bromodomain and Extra-Terminal Domain (BET)-First Bromodomain (BD1) Inhibitors. Journal of medicinal chemistry (2024)
Vishwesh Venkatraman, Jeremiah Gaiser, Daphne Demekas, Amitava Roy, Rui Xiong, Travis J Wheeler
Do Molecular Fingerprints Identify Diverse Active Drugs in Large-Scale Virtual Screening? (No). Pharmaceuticals (Basel, Switzerland) 17 (8) (2024)
Ganga Reddy Velma, Zhengnan Shen, Cameron Holberg, Jiqiang Fu, Farinaz Soleymani, Laura Cooper, Omar Lozano Ramos, Divakar Indukuri, Soumya Reddy Musku, Pavel Rychetsky, Steve Slilaty, Zuomei Li, Kiira Ratia, Lijun Rong, Dominik Schenten, Rui Xiong, Gregory R J Thatcher
Non-Covalent Inhibitors of SARS-CoV-2 Papain-Like Protease (PLpro): In Vitro and In Vivo Antiviral Activity. Journal of medicinal chemistry 67 (16) (2024)
Ganga Reddy Velma, Zhengnan Shen, Cameron Holberg, Jiqiang Fu, Farinaz Soleymani, Laura Cooper, Omar Lozano Ramos, Divakar Indukuri, Soumya Reddy Musku, Pavel Rychetsky, Steve Slilaty, Zuomei Li, Kiira Ratia, Lijun Rong, Dominik Schenten, Rui Xiong, Gregory R J Thatcher
Non-Covalent Inhibitors of SARS-CoV-2 Papain-Like Protease (PLpro): In Vitro and In Vivo Antiviral Activity. Journal of medicinal chemistry 67 (16) (2024)
Yangfeng Li, Zhengnan Shen, Kiira Ratia, Jiong Zhao, Fei Huang, Oleksii Dubrovyskyii, Divakar Indukuri, Jiqiang Fu, Omar Lozano Ramos, Gregory R J Thatcher, Rui Xiong
Structure-Guided Design and Synthesis of Pyridinone-Based Selective Bromodomain and Extra-Terminal Domain (BET)-First Bromodomain (BD1) Inhibitors. Journal of medicinal chemistry 67 (4) (2024)
Daniel R Principe, Rui Xiong, Yangfeng Li, Thao N D Pham, Suneel D Kamath, Oleksii Dubrovskyi, Kiira Ratia, Fei Huang, Jiong Zhao, Zhengnan Shen, Dinesh Thummuri, Zhou Daohong, Patrick W Underwood, Jose Trevino, Hidayatullah G Munshi, Gregory R J Thatcher, Ajay Rana
XP-524 is a dual-BET/EP300 inhibitor that represses oncogenic KRAS and potentiates immune checkpoint inhibition in pancreatic cancer. Proceedings of the National Academy of Sciences of the United States of America 119 (4) (2022)
Zhengnan Shen, Kiira Ratia, Laura Cooper, Deyu Kong, Hyun Lee, Youngjin Kwon, Yangfeng Li, Saad Alqarni, Fei Huang, Oleksii Dubrovskyi, Lijun Rong, Gregory R J Thatcher, Rui Xiong
Design of SARS-CoV-2 PLpro Inhibitors for COVID-19 Antiviral Therapy Leveraging Binding Cooperativity. Journal of medicinal chemistry (2021)
Adam Schafer, Rui Xiong, Laura M Cooper, Raghad Nowar, Hyun Lee, Yangfeng Li, Benjamin E Ramirez, Norton P Peet, Michael Caffrey, Gregory R J Thatcher, Erica Ollmann Saphire, Han Cheng, Lijun Rong
Evidence for distinct mechanisms of small molecule inhibitors of filovirus entry. PLoS pathogens 17 (2) (2021)
Laura Cooper, Adam Schafer, Yangfeng Li, Han Cheng, Bani Medegan Fagla, Zhengnan Shen, Raghad Nowar, Katherine Dye, Manu Anantpadma, Robert A Davey, Gregory R J Thatcher, Lijun Rong, Rui Xiong
Screening and Reverse-Engineering of Estrogen Receptor Ligands as Potent Pan-Filovirus Inhibitors. Journal of medicinal chemistry 63 (19) (2020)
Yangfeng Li, Jiong Zhao, Lauren M Gutgesell, Zhengnan Shen, Kiira Ratia, Katherine Dye, Oleksii Dubrovskyi, Huiping Zhao, Fei Huang, Debra A Tonetti, Gregory R J Thatcher, Rui Xiong
Novel Pyrrolopyridone Bromodomain and Extra-Terminal Motif (BET) Inhibitors Effective in Endocrine-Resistant ER+ Breast Cancer with Acquired Resistance to Fulvestrant and Palbociclib. Journal of medicinal chemistry 63 (13) (2020)
Yunlong Lu, Lauren M Gutgesell, Rui Xiong, Jiong Zhao, Yangfeng Li, Carlo I Rosales, Michael Hollas, Zhengnan Shen, Jesse Gordon-Blake, Katherine Dye, Yueting Wang, Sue Lee, Hu Chen, Donghong He, Oleksii Dubrovyskyii, Huiping Zhao, Fei Huang, Amy W Lasek, Debra A Tonetti, Gregory R J Thatcher
Design and Synthesis of Basic Selective Estrogen Receptor Degraders for Endocrine Therapy Resistant Breast Cancer. Journal of medicinal chemistry 62 (24) (2019)
Rui Xiong, Jiong Zhao, Lauren M Gutgesell, Yueting Wang, Sue Lee, Bhargava Karumudi, Huiping Zhao, Yunlong Lu, Debra A Tonetti, Gregory R J Thatcher
Novel Selective Estrogen Receptor Downregulators (SERDs) Developed against Treatment-Resistant Breast Cancer. Journal of medicinal chemistry 60 (4) (2017)