Sarah L Gaffen (Sarah Gaffen)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 24

Top Topics

Cystic Fibrosis

Binding Protein

Systemic Sclerosis

Top Venues

Journal of immunology (Baltimore, Md. : 1950)

Science immunology

Science signaling

This page only lists publications with an associated author ORCID identifier.

Publications

Ipsita Dey, Yang Li, Tiffany C Taylor, Doureradjou Peroumal, Nariaki Asada, Ulf Panzer, Partha S Biswas, Esta Sterneck, Sarah L Gaffen
C/EBPδ Mediates Immunity to Renal Autoinflammatory Disorders in a Stage-specific Manner. Journal of immunology (Baltimore, Md. : 1950) (2024)
Mostafa Shehabeldin, Jin Gao, Yejin Cho, Rong Chong, Tracy Tabib, Lu Li, Matthew Smardz, Sarah L Gaffen, Patricia I Diaz, Robert A Lafyatis, Steven R Little, Charles Sfeir
Therapeutic delivery of CCL2 modulates immune response and restores host-microbe homeostasis. Proceedings of the National Academy of Sciences of the United States of America 121 (36) (2024)
Felix E Y Aggor, Martinna Bertolini, Bianca M Coleman, Tiffany C Taylor, Nicole O Ponde, Sarah L Gaffen
Combinatorial actions of IL-22 and IL-17 drive optimal immunity to oral candidiasis through SPRRs. PLoS pathogens 20 (7) (2024)
Yang Li, Shachi P Vyas, Isha Mehta, Nariaki Asada, Ipsita Dey, Tiffany C Taylor, Rami Bechara, Nilesh Amatya, Felix E Y Aggor, Bianca M Coleman, De-Dong Li, Kenta Yamamoto, Ogechukwu Ezenwa, Yeque Sun, Esta Sterneck, Charles Joel McManus, Ulf Panzer, Partha S Biswas, Ram Savan, Jishnu Das, Sarah L Gaffen
The RNA binding protein Arid5a drives IL-17-dependent autoantibody-induced glomerulonephritis. The Journal of experimental medicine 221 (9) (2024)
Pallavi Kakade, Juan F Burgueno, Shabnam Sircaik, Nicole O Ponde, Jinke Li, Iuliana V Ene, Jiwoong Kim, Shen-Huan Liang, Rebecca Yunker, Yasutada Akiba, Shipra Vaishnava, Jonathan D Kaunitz, Sing Sing Way, Andrew Y Koh, Sarah L Gaffen, Maria T Abreu, Richard J Bennett
An IL-17-DUOX2 axis controls gastrointestinal colonization by Candida albicans . bioRxiv : the preprint server for biology (2024)
Mostafa Shehabeldin, Jin Gao, Yejin Cho, Rong Chong, Tracy Tabib, Lu Li, Matthew Smardz, Sarah L Gaffen, Patricia I Diaz, Robert A Lafyatis, Steven R Little, Charles Sfeir
Therapeutic delivery of CCL2 modulates immune response and restores host-microbe homeostasis. Proceedings of the National Academy of Sciences of the United States of America 121 (36) (2024)
Yang Li, Shachi P Vyas, Isha Mehta, Nariaki Asada, Ipsita Dey, Tiffany C Taylor, Rami Bechara, Nilesh Amatya, Felix E Y Aggor, Bianca M Coleman, De-Dong Li, Kenta Yamamoto, Ogechukwu Ezenwa, Yeque Sun, Esta Sterneck, Charles Joel McManus, Ulf Panzer, Partha S Biswas, Ram Savan, Jishnu Das, Sarah L Gaffen
The RNA binding protein Arid5a drives IL-17-dependent autoantibody-induced glomerulonephritis. The Journal of experimental medicine 221 (9) (2024)
Felix E Y Aggor, Martinna Bertolini, Bianca M Coleman, Tiffany C Taylor, Nicole O Ponde, Sarah L Gaffen
Combinatorial actions of IL-22 and IL-17 drive optimal immunity to oral candidiasis through SPRRs. PLoS pathogens 20 (7) (2024)
Felix E Y Aggor, Martinna Bertolini, Bianca M Coleman, Tiffany C Taylor, Nicole O Ponde, Sarah L Gaffen
Combinatorial actions of IL-22 and IL-17 drive optimal immunity to oral candidiasis through SPRRs. PLoS pathogens 20 (7) (2024)
Shankar K Revu, Wenjuan Yang, Dhivyaa Rajasundaram, Alexander Brady, Saikat Majumder, Sarah L Gaffen, William F Hawse, Zongqi Xia, Mandy J McGeachy
Human IL-17A protein production is controlled through a PIP5K1α-dependent translational checkpoint. Science signaling 16 (808) (2023)
Nicole O Ponde, Karsen E Shoger, Mst Shamima Khatun, Mrinal K Sarkar, Ipsita Dey, Tiffany C Taylor, Rylee N Cisney, Samyuktha P Arunkumar, Johann E Gudjonsson, Jay K Kolls, Rachel A Gottschalk, Sarah L Gaffen
SARS-CoV-2 ORF8 Mediates Signals in Macrophages and Monocytes through MyD88 Independently of the IL-17 Receptor. Journal of immunology (Baltimore, Md. : 1950) (2023)
Rami Bechara, Nilesh Amatya, Rachel D Bailey, Yang Li, Felix E Y Aggor, De-Dong Li, Chetan V Jawale, Bianca M Coleman, Ning Dai, Nandan S Gokhale, Tiffany C Taylor, Stacy M Horner, Amanda C Poholek, Anita Bansal, Partha S Biswas, Sarah L Gaffen
The m6A reader IMP2 directs autoimmune inflammation through an IL-17- and TNFα-dependent C/EBP transcription factor axis. Science immunology 6 (61) (2022)
Spyridoula-Angeliki Nikou, Chunsheng Zhou, James S Griffiths, Natalia K Kotowicz, Bianca M Coleman, Mary J Green, David L Moyes, Sarah L Gaffen, Julian R Naglik, Peter J Parker
The Candida albicans toxin candidalysin mediates distinct epithelial inflammatory responses through p38 and EGFR-ERK pathways. Science signaling 15 (728) (2022)
Tiffany C Taylor, Yang Li, De-Dong Li, Saikat Majumder, Mandy J McGeachy, Partha S Biswas, Sebastien Gingras, Sarah L Gaffen
Arid5a Mediates an IL-17-Dependent Pathway That Drives Autoimmunity but Not Antifungal Host Defense. Journal of immunology (Baltimore, Md. : 1950) 209 (6) (2022)
Cinthia M F Pacheco, Katia Lucy Melo Maltos, Mostafa S Shehabeldin, Laura L Thomas, Zhe Zhuang, Sayuri Yoshizawa, Konstantinos Verdelis, Sarah L Gaffen, Gustavo P Garlet, Steven R Little, Charles Sfeir
Local Sustained Delivery of Anti-IL-17A Antibodies Limits Inflammatory Bone Loss in Murine Experimental Periodontitis. Journal of immunology (Baltimore, Md. : 1950) 206 (10) (2021)
Chetan V Jawale, Kritika Ramani, De-Dong Li, Bianca M Coleman, Rohan S Oberoi, Saran Kupul, Li Lin, Jigar V Desai, Greg M Delgoffe, Michail S Lionakis, Filitsa H Bender, Alexander J Prokopienko, Thomas D Nolin, Sarah L Gaffen, Partha S Biswas
Restoring glucose uptake rescues neutrophil dysfunction and protects against systemic fungal infection in mouse models of kidney disease. Science translational medicine 12 (548) (2021)
Felix E Y Aggor, Timothy J Break, Giraldina Trevejo-Nuñez, Natasha Whibley, Bianca M Coleman, Rachel D Bailey, Daniel H Kaplan, Julian R Naglik, Wei Shan, Amol Carl Shetty, Carrie McCracken, Scott K Durum, Partha S Biswas, Vincent M Bruno, Jay K Kolls, Michail S Lionakis, Sarah L Gaffen
Oral epithelial IL-22/STAT3 signaling licenses IL-17-mediated immunity to oral mucosal candidiasis. Science immunology 5 (48) (2021)
Chunsheng Zhou, Leticia Monin, Rachael A Gordon, Felix E Y Aggor, Rami Bechara, Tara N Edwards, Daniel H Kaplan, Sebastien Gingras, Sarah L Gaffen
An IL-17F.S65L Knock-In Mouse Reveals Similarities and Differences in IL-17F Function in Oral Candidiasis: A New Tool to Understand IL-17F. Journal of immunology (Baltimore, Md. : 1950) 205 (3) (2020)
Sarah L Gaffen, Niki M Moutsopoulos
Regulation of host-microbe interactions at oral mucosal barriers by type 17 immunity. Science immunology 5 (43) (2020)
Xiaoxia Li, Rami Bechara, Junjie Zhao, Mandy J McGeachy, Sarah L Gaffen
IL-17 receptor-based signaling and implications for disease. Nature immunology 20 (12) (2019)
Fang Shen, Akash H Verma, Amy Volk, Brian Jones, Bianca M Coleman, Matthew J Loza, Ravi Malaviya, Beverley A Moore, Daniel Weinstock, M Merle Elloso, Sarah L Gaffen, Tatiana Ort
Combined Blockade of TNF-α and IL-17A Alleviates Progression of Collagen-Induced Arthritis without Causing Serious Infections in Mice. Journal of immunology (Baltimore, Md. : 1950) 202 (7) (2019)
Akash H Verma, Hanna Zafar, Nicole O Ponde, Olivia W Hepworth, Diksha Sihra, Felix E Y Aggor, Joseph S Ainscough, Jemima Ho, Jonathan P Richardson, Bianca M Coleman, Bernhard Hube, Martin Stacey, Mandy J McGeachy, Julian R Naglik, Sarah L Gaffen, David L Moyes
IL-36 and IL-1/IL-17 Drive Immunity to Oral Candidiasis via Parallel Mechanisms. Journal of immunology (Baltimore, Md. : 1950) 201 (2) (2018)
Akash H Verma, Jonathan P Richardson, Chunsheng Zhou, Bianca M Coleman, David L Moyes, Jemima Ho, Anna R Huppler, Kritika Ramani, Mandy J McGeachy, Ilgiz A Mufazalov, Esther Von Stebut, Lawrence P Kane, Partha S Biswas, Bernhard Hube, Julian R Naglik, Sarah L Gaffen
Oral epithelial cells orchestrate innate type 17 responses to Candida albicans through the virulence factor candidalysin. Science immunology 2 (17) (2018)
Nilesh Amatya, Erin E Childs, J Agustin Cruz, Felix E Y Aggor, Abhishek V Garg, Andrea J Berman, Johann E Gudjonsson, Ulus Atasoy, Sarah L Gaffen
IL-17 integrates multiple self-reinforcing, feed-forward mechanisms through the RNA binding protein Arid5a. Science signaling 11 (551) (2018)