Sebastian Guettler

Years Active: 2017-2024
Publications (10 Years): 5

Institute of Cancer Research

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Institute of Cancer Research

United Kingdom

Team Leader :: Divisions of Structural and Cancer Biology

Publications

Matthew Jessop, Benjamin J Broadway, Katy Miller, Sebastian Guettler
Regulation of PARP1/2 and the tankyrases: emerging parallels. The Biochemical journal 481 (17) (2024)
Nisha Pillay, Laura Mariotti, Mariola Zaleska, Oviya Inian, Matthew Jessop, Sam Hibbs, Ambroise Desfosses, Paul C R Hopkins, Catherine M Templeton, Fabienne Beuron, Edward P Morris, Sebastian Guettler
Structural basis of tankyrase activation by polymerization. Nature 612 (7938) (2022)
Katie Pollock, Manjuan Liu, Mariola Zaleska, Mirco Meniconi, Mark Pfuhl, Ian Collins, Sebastian Guettler
Fragment-based screening identifies molecules targeting the substrate-binding ankyrin repeat domains of tankyrase. Scientific reports 9 (1) (2019)
Stephen J Pettitt, Dragomir B Krastev, Inger Brandsma, Amy Dréan, Feifei Song, Radoslav Aleksandrov, Maria I Harrell, Malini Menon, Rachel Brough, James Campbell, Jessica Frankum, Michael Ranes, Helen N Pemberton, Rumana Rafiq, Kerry Fenwick, Amanda Swain, Sebastian Guettler, Jung-Min Lee, Elizabeth M Swisher, Stoyno Stoynov, Kosuke Yusa, Alan Ashworth, Christopher J Lord
Genome-wide and high-density CRISPR-Cas9 screens identify point mutations in PARP1 causing PARP inhibitor resistance. Nature communications 9 (1) (2018)
Laura Mariotti, Katie Pollock, Sebastian Guettler
Regulation of Wnt/β-catenin signalling by tankyrase-dependent poly(ADP-ribosyl)ation and scaffolding. British journal of pharmacology 174 (24) (2017)

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