Shu-Sin Chng (Shu Sin Chng)

Scopus Author ID ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2016-2023
Publications (10 Years): 19

Top Venues

mBio

Molecular microbiology

The Journal of biological chemistry

Proceedings of the National Academy of Sciences of the United States of America

National University of Singapore

Harvard University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

National University of Singapore

Singapore

Associate Professor :: Chemistry

Singapore Center for Environmental Life Sciences Engineering

Singapore

Principal Investigator

National University of Singapore

Singapore

Assistant Professor :: Chemistry

Harvard Medical School

United States

Postdoctoral fellow :: Microbiology and Immunobiology

National University of Singapore

Singapore

Research assistant :: Chemistry

Education History

Harvard University

United States

PHD :: Chemistry and Chemical Biology

National University of Singapore

Singapore

BSC :: Chemistry

Publications

Jiang Yeow, Min Luo, Shu-Sin Chng
Molecular mechanism of phospholipid transport at the bacterial outer membrane interface. Nature communications 14 (1) (2023)
Rafi Rashid, Zeus Jaren Nair, Dominic Ming Hao Chia, Kelvin Kian Long Chong, Amaury Cazenave Gassiot, Stewart A Morley, Doug K Allen, Swaine L Chen, Shu-Sin Chng, Markus R Wenk, Kimberly Ann Kline
Depleting Cationic Lipids Involved in Antimicrobial Resistance Drives Adaptive Lipid Remodeling in Enterococcus faecalis. mBio 14 (1) (2023)
Rafi Rashid, Zeus Jaren Nair, Dominic Ming Hao Chia, Kelvin Kian Long Chong, Amaury Cazenave Gassiot, Stewart A Morley, Doug K Allen, Swaine L Chen, Shu-Sin Chng, Markus R Wenk, Kimberly Ann Kline
Depleting Cationic Lipids Involved in Antimicrobial Resistance Drives Adaptive Lipid Remodeling in Enterococcus faecalis. mBio 14 (1) (2023)
Rafi Rashid, Zeus Jaren Nair, Dominic Ming Hao Chia, Kelvin Kian Long Chong, Amaury Cazenave Gassiot, Stewart A Morley, Doug K Allen, Swaine L Chen, Shu-Sin Chng, Markus R Wenk, Kimberly Ann Kline
Depleting Cationic Lipids Involved in Antimicrobial Resistance Drives Adaptive Lipid Remodeling in Enterococcus faecalis. mBio (2023)
Rafi Rashid, Zeus Jaren Nair, Dominic Ming Hao Chia, Kelvin Kian Long Chong, Amaury Cazenave Gassiot, Stewart A Morley, Doug K Allen, Swaine L Chen, Shu-Sin Chng, Markus R Wenk, Kimberly Ann Kline
Depleting Cationic Lipids Involved in Antimicrobial Resistance Drives Adaptive Lipid Remodeling in Enterococcus faecalis. mBio 14 (1) (2023)
Yushu Chen, Yuchun Wang, Shu-Sin Chng
A conserved membrane protein negatively regulates Mce1 complexes in mycobacteria. Nature communications 14 (1) (2023)
Wen-Yi Low, Shuhua Thong, Shu-Sin Chng
ATP disrupts lipid-binding equilibrium to drive retrograde transport critical for bacterial outer membrane asymmetry. Proceedings of the National Academy of Sciences of the United States of America 118 (50) (2022)
Wee Boon Tan, Shu-Sin Chng
Genetic interaction mapping highlights key roles of the Tol-Pal complex. Molecular microbiology 117 (4) (2022)
Emily C A Goodall, Georgia L Isom, Jessica L Rooke, Karthik Pullela, Christopher Icke, Zihao Yang, Gabriela Boelter, Alun Jones, Isabel A Warner, Rochelle M Da Costa, Bing Zhang, James Rae, Wee Boon Tan, Matthias Winkle, Antoine Delhaye, Eva Heinz, Jean-Francois Collet, Adam F Cunningham, Mark A T Blaskovich, Robert G Parton, Jeff A Cole, Manuel Banzhaf, Shu-Sin Chng, Waldemar Vollmer, Jack A Bryant, Ian R Henderson
Loss of YhcB results in dysregulation of coordinated peptidoglycan, LPS and phospholipid synthesis during Escherichia coli cell growth. PLoS genetics 17 (12) (2021)
Jack A Bryant, Ian T Cadby, Zhi-Soon Chong, Gabriela Boelter, Yanina R Sevastsyanovich, Faye C Morris, Adam F Cunningham, George Kritikos, Richard W Meek, Manuel Banzhaf, Shu-Sin Chng, Andrew L Lovering, Ian R Henderson
Structure-Function Characterization of the Conserved Regulatory Mechanism of the Escherichia coli M48 Metalloprotease BepA. Journal of bacteriology 203 (2) (2020)
Jack Alfred Bryant, Faye C Morris, Timothy J Knowles, Riyaz Maderbocus, Eva Heinz, Gabriela Boelter, Dema Alodaini, Adam Colyer, Peter J Wotherspoon, Kara A Staunton, Mark Jeeves, Douglas F Browning, Yanina R Sevastsyanovich, Timothy J Wells, Amanda E Rossiter, Vassiliy N Bavro, Pooja Sridhar, Douglas G Ward, Zhi-Soon Chong, Emily C A Goodall, Christopher Icke, Alvin Ck Teo, Shu-Sin Chng, David I Roper, Trevor Lithgow, Adam F Cunningham, Manuel Banzhaf, Michael Overduin, Ian R Henderson
Structure of dual BON-domain protein DolP identifies phospholipid binding as a new mechanism for protein localisation. eLife 9 (2020)
Xiang'Er Jiang, Wee Boon Tan, Rahul Shrivastava, Deborah Chwee San Seow, Swaine Lin Chen, Xue Li Guan, Shu-Sin Chng
Mutations in enterobacterial common antigen biosynthesis restore outer membrane barrier function in Escherichia coli tol-pal mutants. Molecular microbiology 114 (6) (2020)
Ming Li, Zheng Yen Phua, Yu Xi, Zhujun Xu, Samuel A Nyantakyi, Wei Li, Mary Jackson, Ming Wah Wong, Yulin Lam, Shu-Sin Chng, Mei Lin Go, Thomas Dick
Potency Increase of Spiroketal Analogs of Membrane Inserting Indolyl Mannich Base Antimycobacterials Is Due to Acquisition of MmpL3 Inhibition. ACS infectious diseases 6 (7) (2020)
Christian Dupont, Yushu Chen, Zhujun Xu, Françoise Roquet-Banères, Mickaël Blaise, Anne-Kathrin Witt, Faustine Dubar, Christophe Biot, Yann Guérardel, Florian P Maurer, Shu-Sin Chng, Laurent Kremer
A piperidinol-containing molecule is active against Mycobacterium tuberculosis by inhibiting the mycolic acid flippase activity of MmpL3. The Journal of biological chemistry 294 (46) (2019)
Rahul Shrivastava, Shu-Sin Chng
Lipid trafficking across the Gram-negative cell envelope. The Journal of biological chemistry 294 (39) (2019)
Bilge Ercan, Wen-Yi Low, Xuejun Liu, Shu-Sin Chng
Characterization of Interactions and Phospholipid Transfer between Substrate Binding Proteins of the OmpC-Mla System. Biochemistry 58 (2) (2018)
Zhujun Xu, Vladimir A Meshcheryakov, Giovanna Poce, Shu-Sin Chng
MmpL3 is the flippase for mycolic acids in mycobacteria. Proceedings of the National Academy of Sciences of the United States of America 114 (30) (2017)
Rahul Shrivastava, Xiang'Er Jiang, Shu-Sin Chng
Outer membrane lipid homeostasis via retrograde phospholipid transport in Escherichia coli. Molecular microbiology 106 (3) (2017)
Shuhua Thong, Bilge Ercan, Federico Torta, Zhen Yang Fong, Hui Yi Alvina Wong, Markus R Wenk, Shu-Sin Chng
Defining key roles for auxiliary proteins in an ABC transporter that maintains bacterial outer membrane lipid asymmetry. eLife 5 (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Shu-Sin Chng (Shu Sin Chng)