Siddharth Balachandran

ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 17

Top Venues

Nature

Proceedings of the National Academy of Sciences of the United States of America

Cancer discovery

The Journal of cell biology

Fox Chase Cancer Center

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Fox Chase Cancer Center Sep 01 2007

United States

Professor :: Blood Cell Development and Function

Publications

Avishekh Gautam, David F Boyd, Sameer Nikhar, Ting Zhang, Ioannis Siokas, Lee-Ann Van de Velde, Jessica Ann Gaevert, Victoria A Meliopoulos, Bikash Thapa, Diego A Rodriguez, Kathy Q Cai, Chaoran Yin, Daniel Schnepf, Julius Beer, Carly DeAntoneo, Riley M Williams, Maria Shubina, Brandi Livingston, Dingqiang Zhang, Mark D Andrake, Seungheon Lee, Raghavender Boda, Anantha L Duddupudi, Jeremy Chase Crawford, Peter Vogel, Christian Loch, Martin Schwemmle, Lawrence C Fritz, Stacey Schultz-Cherry, Douglas R Green, Gregory D Cuny, Paul Glyndwr Thomas, Alexei Degterev, Siddharth Balachandran
Necroptosis blockade prevents lung injury in severe influenza. Nature 628 (8009) (2024)
Avishekh Gautam, David F Boyd, Sameer Nikhar, Ting Zhang, Ioannis Siokas, Lee-Ann Van de Velde, Jessica Ann Gaevert, Victoria A Meliopoulos, Bikash Thapa, Diego A Rodriguez, Kathy Q Cai, Chaoran Yin, Daniel Schnepf, Julius Beer, Carly DeAntoneo, Riley M Williams, Maria Shubina, Brandi Livingston, Dingqiang Zhang, Mark D Andrake, Seungheon Lee, Raghavender Boda, Anantha L Duddupudi, Jeremy Chase Crawford, Peter Vogel, Christian Loch, Martin Schwemmle, Lawrence C Fritz, Stacey Schultz-Cherry, Douglas R Green, Gregory D Cuny, Paul Glyndwr Thomas, Alexei Degterev, Siddharth Balachandran
Necroptosis blockade prevents lung injury in severe influenza. Nature 628 (8009) (2024)
Avishekh Gautam, David F Boyd, Sameer Nikhar, Ting Zhang, Ioannis Siokas, Lee-Ann Van de Velde, Jessica Ann Gaevert, Victoria A Meliopoulos, Bikash Thapa, Diego A Rodriguez, Kathy Q Cai, Chaoran Yin, Daniel Schnepf, Julius Beer, Carly DeAntoneo, Riley M Williams, Maria Shubina, Brandi Livingston, Dingqiang Zhang, Mark D Andrake, Seungheon Lee, Raghavender Boda, Anantha L Duddupudi, Jeremy Chase Crawford, Peter Vogel, Christian Loch, Martin Schwemmle, Lawrence C Fritz, Stacey Schultz-Cherry, Douglas R Green, Gregory D Cuny, Paul Glyndwr Thomas, Alexei Degterev, Siddharth Balachandran
Necroptosis blockade prevents lung injury in severe influenza. Nature 628 (8009) (2024)
Avishekh Gautam, David F Boyd, Sameer Nikhar, Ting Zhang, Ioannis Siokas, Lee-Ann Van de Velde, Jessica Ann Gaevert, Victoria A Meliopoulos, Bikash Thapa, Diego A Rodriguez, Kathy Q Cai, Chaoran Yin, Daniel Schnepf, Julius Beer, Carly DeAntoneo, Riley M Williams, Maria Shubina, Brandi Livingston, Dingqiang Zhang, Mark D Andrake, Seungheon Lee, Raghavender Boda, Anantha L Duddupudi, Jeremy Chase Crawford, Peter Vogel, Christian Loch, Martin Schwemmle, Lawrence C Fritz, Stacey Schultz-Cherry, Douglas R Green, Gregory D Cuny, Paul Glyndwr Thomas, Alexei Degterev, Siddharth Balachandran
Necroptosis blockade prevents lung injury in severe influenza. Nature 628 (8009) (2024)
Avishekh Gautam, David F Boyd, Sameer Nikhar, Ting Zhang, Ioannis Siokas, Lee-Ann Van de Velde, Jessica Ann Gaevert, Victoria A Meliopoulos, Bikash Thapa, Diego A Rodriguez, Kathy Q Cai, Chaoran Yin, Daniel Schnepf, Julius Beer, Carly DeAntoneo, Riley M Williams, Maria Shubina, Brandi Livingston, Dingqiang Zhang, Mark D Andrake, Seungheon Lee, Raghavender Boda, Anantha L Duddupudi, Jeremy Chase Crawford, Peter Vogel, Christian Loch, Martin Schwemmle, Lawrence C Fritz, Stacey Schultz-Cherry, Douglas R Green, Gregory D Cuny, Paul Glyndwr Thomas, Alexei Degterev, Siddharth Balachandran
Necroptosis blockade prevents lung injury in severe influenza. Nature 628 (8009) (2024)
Avishekh Gautam, David F Boyd, Sameer Nikhar, Ting Zhang, Ioannis Siokas, Lee-Ann Van de Velde, Jessica Ann Gaevert, Victoria A Meliopoulos, Bikash Thapa, Diego A Rodriguez, Kathy Q Cai, Chaoran Yin, Daniel Schnepf, Julius Beer, Carly DeAntoneo, Riley M Williams, Maria Shubina, Brandi Livingston, Dingqiang Zhang, Mark D Andrake, Seungheon Lee, Raghavender Boda, Anantha L Duddupudi, Jeremy Chase Crawford, Peter Vogel, Christian Loch, Martin Schwemmle, Lawrence C Fritz, Stacey Schultz-Cherry, Douglas R Green, Gregory D Cuny, Paul Glyndwr Thomas, Alexei Degterev, Siddharth Balachandran
Necroptosis blockade prevents lung injury in severe influenza. Nature 628 (8009) (2024)
Takahiko Murayama, Jun Nakayama, Xinpei Jiang, Kenichi Miyata, Alexander D Morris, Kathy Q Cai, Rahul M Prasad, Xueying Ma, Andrey Efimov, Neel Belani, Emily R Gerstein, Yin Fei Tan, Yan Zhou, Jong Wook Kim, Reo Maruyama, Kerry S Campbell, Lu Chen, Yibin Yang, Siddharth Balachandran, Israel Cañadas
Targeting DHX9 triggers tumor-intrinsic interferon response and replication stress in Small Cell Lung Cancer. Cancer discovery (2024)
Avishekh Gautam, David F Boyd, Sameer Nikhar, Ting Zhang, Ioannis Siokas, Lee-Ann Van de Velde, Jessica Ann Gaevert, Victoria A Meliopoulos, Bikash Thapa, Diego A Rodriguez, Kathy Q Cai, Chaoran Yin, Daniel Schnepf, Julius Beer, Carly DeAntoneo, Riley M Williams, Maria Shubina, Brandi Livingston, Dingqiang Zhang, Mark D Andrake, Seungheon Lee, Raghavender Boda, Anantha L Duddupudi, Jeremy Chase Crawford, Peter Vogel, Christian Loch, Martin Schwemmle, Lawrence C Fritz, Stacey Schultz-Cherry, Douglas R Green, Gregory D Cuny, Paul Glyndwr Thomas, Alexei Degterev, Siddharth Balachandran
Necroptosis blockade prevents lung injury in severe influenza. Nature (2024)
Avishekh Gautam, David F Boyd, Sameer Nikhar, Ting Zhang, Ioannis Siokas, Lee-Ann Van de Velde, Jessica Ann Gaevert, Victoria A Meliopoulos, Bikash Thapa, Diego A Rodriguez, Kathy Q Cai, Chaoran Yin, Daniel Schnepf, Julius Beer, Carly DeAntoneo, Riley M Williams, Maria Shubina, Brandi Livingston, Dingqiang Zhang, Mark D Andrake, Seungheon Lee, Raghavender Boda, Anantha L Duddupudi, Jeremy Chase Crawford, Peter Vogel, Christian Loch, Martin Schwemmle, Lawrence C Fritz, Stacey Schultz-Cherry, Douglas R Green, Gregory D Cuny, Paul Glyndwr Thomas, Alexei Degterev, Siddharth Balachandran
Necroptosis blockade prevents lung injury in severe influenza. Nature 628 (8009) (2024)
Takahiko Murayama, Jun Nakayama, Xinpei Jiang, Kenichi Miyata, Alexander D Morris, Kathy Q Cai, Rahul M Prasad, Xueying Ma, Andrey Efimov, Neel Belani, Emily R Gerstein, Yin Fei Tan, Yan Zhou, Jong Wook Kim, Reo Maruyama, Kerry S Campbell, Lu Chen, Yibin Yang, Siddharth Balachandran, Israel Cañadas
Targeting DHX9 Triggers Tumor-Intrinsic Interferon Response and Replication Stress in Small Cell Lung Cancer. Cancer discovery 14 (3) (2024)
Avishekh Gautam, David F Boyd, Sameer Nikhar, Ting Zhang, Ioannis Siokas, Lee-Ann Van de Velde, Jessica Ann Gaevert, Victoria A Meliopoulos, Bikash Thapa, Diego A Rodriguez, Kathy Q Cai, Chaoran Yin, Daniel Schnepf, Julius Beer, Carly DeAntoneo, Riley M Williams, Maria Shubina, Brandi Livingston, Dingqiang Zhang, Mark D Andrake, Seungheon Lee, Raghavender Boda, Anantha L Duddupudi, Jeremy Chase Crawford, Peter Vogel, Christian Loch, Martin Schwemmle, Lawrence C Fritz, Stacey Schultz-Cherry, Douglas R Green, Gregory D Cuny, Paul Glyndwr Thomas, Alexei Degterev, Siddharth Balachandran
Necroptosis blockade prevents lung injury in severe influenza. Nature 628 (8009) (2024)
Avishekh Gautam, David F Boyd, Sameer Nikhar, Ting Zhang, Ioannis Siokas, Lee-Ann Van de Velde, Jessica Ann Gaevert, Victoria A Meliopoulos, Bikash Thapa, Diego A Rodriguez, Kathy Q Cai, Chaoran Yin, Daniel Schnepf, Julius Beer, Carly DeAntoneo, Riley M Williams, Maria Shubina, Brandi Livingston, Dingqiang Zhang, Mark D Andrake, Seungheon Lee, Raghavender Boda, Anantha L Duddupudi, Jeremy Chase Crawford, Peter Vogel, Christian Loch, Martin Schwemmle, Lawrence C Fritz, Stacey Schultz-Cherry, Douglas R Green, Gregory D Cuny, Paul Glyndwr Thomas, Alexei Degterev, Siddharth Balachandran
Necroptosis blockade prevents lung injury in severe influenza. Nature (2024)
Hayley I Muendlein, Wilson M Connolly, Zoie Magri, David Jetton, Irina Smirnova, Alexei Degterev, Siddharth Balachandran, Alexander Poltorak
ZBP1 promotes inflammatory responses downstream of TLR3/TLR4 via timely delivery of RIPK1 to TRIF. Proceedings of the National Academy of Sciences of the United States of America 119 (24) (2022)
Ting Zhang, Chaoran Yin, Aleksandr Fedorov, Liangjun Qiao, Hong-Liang Bao, Nazar Beknazarov, Shiyu Wang, Avishekh Gautam, Riley M Williams, Jeremy Chase Crawford, Suraj Peri, Vasily M Studitsky, Amer A Beg, Paul Glyndwr Thomas, Carl R Walkley, Yan Xu, Maria Poptsova, Alan Herbert, Siddharth Balachandran
ADAR1 masks the cancer immunotherapeutic promise of ZBP1-driven necroptosis. Nature 606 (7914) (2022)
Diego A Rodriguez, Giovanni Quarato, Swantje Liedmann, Bart Tummers, Ting Zhang, Cliff Guy, Jeremy Chase Crawford, Gustavo Palacios, Stephane Pelletier, Halime Kalkavan, Jeremy J P Shaw, Patrick Fitzgerald, Mark J Chen, Siddharth Balachandran, Douglas R Green
Caspase-8 and FADD prevent spontaneous ZBP1 expression and necroptosis. Proceedings of the National Academy of Sciences of the United States of America 119 (41) (2022)
Jared Mamrot, Siddharth Balachandran, Edward J Steele, Robyn A Lindley
Molecular model linking Th2 polarized M2 tumour-associated macrophages with deaminase-mediated cancer progression mutation signatures. Scandinavian journal of immunology 89 (5) (2019)
Ting Zhang, Siddharth Balachandran
Bayonets over bombs: RIPK3 and MLKL restrict Listeria without triggering necroptosis. The Journal of cell biology 218 (6) (2019)

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Publication Activity (10 Years)

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Siddharth Balachandran