Carl R Walkley (Carl Walkley)

Scopus Author ID Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 24

Top Venues

Nature communications

Genome biology

Scientific reports

EMBO reports

Australian Catholic University

University of Melbourne (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Australian Catholic University

Australia

Associate Professor :: Mary MacKillop Institute for Health Research

St Vincent's Institute of Medical Research

Australia

Head, Cancer and RNA Biology Laboratory :: Cancer and RNA Biology Laboratory

Dana Farber Cancer Institute

United States

Research Fellow with Prof Stuart Orkin :: Pediatric Oncology

Education History

University of Melbourne

Australia

PHD :: Peter MacCallum Cancer Centre and Department of Medicine, St Vincent's Hospital

Publications

Peter Truong, Sylvie Shen, Swapna Joshi, Md Imtiazul Islam, Ling Zhong, Mark J Raftery, Ali Afrasiabi, Hamid Alinejad-Rokny, Mary Nguyen, Xiaoheng Zou, Golam Sarower Bhuyan, Chowdhury H Sarowar, Elaheh S Ghodousi, Olivia Stonehouse, Sara Mohamed, Cara E Toscan, Patrick Connerty, Purvi M Kakadia, Stefan K Bohlander, Katharine A Michie, Jonas Larsson, Richard B Lock, Carl R Walkley, Julie A I Thoms, Christopher J Jolly, John E Pimanda
TOPORS E3 ligase mediates resistance to hypomethylating agent cytotoxicity in acute myeloid leukemia cells. Nature communications 15 (1) (2024)
Peter Truong, Sylvie Shen, Swapna Joshi, Md Imtiazul Islam, Ling Zhong, Mark J Raftery, Ali Afrasiabi, Hamid Alinejad-Rokny, Mary Nguyen, Xiaoheng Zou, Golam Sarower Bhuyan, Chowdhury H Sarowar, Elaheh S Ghodousi, Olivia Stonehouse, Sara Mohamed, Cara E Toscan, Patrick Connerty, Purvi M Kakadia, Stefan K Bohlander, Katharine A Michie, Jonas Larsson, Richard B Lock, Carl R Walkley, Julie A I Thoms, Christopher J Jolly, John E Pimanda
TOPORS E3 ligase mediates resistance to hypomethylating agent cytotoxicity in acute myeloid leukemia cells. Nature communications 15 (1) (2024)
Zhen Liang, Alistair M Chalk, Scott Taylor, Ankita Goradia, Jacki E Heraud-Farlow, Carl R Walkley
The phenotype of the most common human ADAR1p150 Zα mutation P193A in mice is partially penetrant. EMBO reports (2023)
Zhen Liang, Ankita Goradia, Carl R Walkley, Jacki E Heraud-Farlow
Generation of a new Adar1p150-/- mouse demonstrates isoform-specific roles in embryonic development and adult homeostasis. RNA (New York, N.Y.) (2023)
Shi-Bin Hu, Jacki E Heraud-Farlow, Tao Sun, Zhen Liang, Ankita Goradia, Scott Taylor, Carl R Walkley, Jin Billy Li
ADAR1p150 Prevents MDA5 and PKR Activation via Distinct Mechanisms to Avert Fatal Autoinflammation. bioRxiv : the preprint server for biology (2023)
Vijesh G Vaghjiani, Catherine R Cochrane, W Samantha N Jayasekara, Wai Chin Chong, Anette Szczepny, Beena Kumar, Luciano G Martelotto, Andrew McCaw, Kirstyn Carey, Maya Kansara, David M Thomas, Carl R Walkley, Stuart Mudge, Daniel J Gough, Peter A Downie, Craig D Peacock, William Matsui, D Neil Watkins, Jason E Cain
Ligand-dependent hedgehog signaling maintains an undifferentiated, malignant osteosarcoma phenotype. Oncogene (2023)
Carl R Walkley
Patience is a virtue. Blood 139 (4) (2022)
Tram Anh Nguyen, Jia Wei Joel Heng, Pornchai Kaewsapsak, Eng Piew Louis Kok, Dominik Stanojević, Hao Liu, Angelysia Cardilla, Albert Praditya, Zirong Yi, Mingwan Lin, Jong Ghut Ashley Aw, Yin Ying Ho, Esther Kai Lay Peh, Yuanming Wang, Qixing Zhong, Jacki E Heraud-Farlow, Shifeng Xue, Bruno Reversade, Carl R Walkley, Ying Swan Ho, Mile Šikić, Yue Wan, Meng How Tan
Direct identification of A-to-I editing sites with nanopore native RNA sequencing. Nature methods 19 (7) (2022)
Ting Zhang, Chaoran Yin, Aleksandr Fedorov, Liangjun Qiao, Hong-Liang Bao, Nazar Beknazarov, Shiyu Wang, Avishekh Gautam, Riley M Williams, Jeremy Chase Crawford, Suraj Peri, Vasily M Studitsky, Amer A Beg, Paul Glyndwr Thomas, Carl R Walkley, Yan Xu, Maria Poptsova, Alan Herbert, Siddharth Balachandran
ADAR1 masks the cancer immunotherapeutic promise of ZBP1-driven necroptosis. Nature 606 (7914) (2022)
Jane Jialu Xu, Alistair M Chalk, Meaghan Wall, Wallace Y Langdon, Monique F Smeets, Carl R Walkley
Srsf2 P95H/+ co-operates with loss of TET2 to promote myeloid bias and initiate a chronic myelomonocytic leukemia-like disease in mice. Leukemia 36 (12) (2022)
Jane Jialu Xu, Alistair M Chalk, Iva Nikolic, Kaylene J Simpson, Monique F Smeets, Carl R Walkley
Genome-wide screening identifies cell cycle control as a synthetic lethal pathway with SRSF2P95H mutation. Blood advances (2021)
Wilson Castillo-Tandazo, Ann E Frazier, Natalie A Sims, Monique F Smeets, Carl R Walkley
Rothmund-Thomson Syndrome-like RECQL4 truncating mutations cause a haploinsufficient low bone mass phenotype in mice. Molecular and cellular biology (2020)
Therese Vu, Jasmin Straube, Amy H Porter, Megan Bywater, Axia Song, Victoria Y Ling, Leanne Cooper, Gabor Pali, Claudia Bruedigam, Sebastien Jacquelin, Joanne Green, Graham Magor, Andrew Charles Perkins, Alistair M Chalk, Carl R Walkley, Florian H Heidel, Pamela Mukhopadhyay, Nicole Cloonan, Stefan Gröschel, Jan Philipp Mallm, Stefan Fröhling, Claudia Scholl, Steven W Lane
Hematopoietic stem and progenitor cell-restricted Cdx2 expression induces transformation to myelodysplasia and acute leukemia. Nature communications 11 (1) (2020)
Matthew Ku, Ruth N MacKinnon, Meaghan Wall, Nisha Narayan, Carl R Walkley, Heung-Chin Cheng, Lynda J Campbell, Louise E Purton, Harshal Nandurkar
Hemopoietic Cell Kinase amplification with Protein Tyrosine Phosphatase Receptor T depletion leads to polycythemia, aberrant marrow erythoid maturation, and splenomegaly. Scientific reports 9 (1) (2019)
Alistair M Chalk, Scott Taylor, Jacki E Heraud-Farlow, Carl R Walkley
The majority of A-to-I RNA editing is not required for mammalian homeostasis. Genome biology 20 (1) (2019)
Wilson Castillo-Tandazo, Monique F Smeets, Vincent J Murphy, Rui Liu, Charlotte Hodson, Jörg Heierhorst, Andrew J Deans, Carl R Walkley
ATP-dependent helicase activity is dispensable for the physiological functions of Recql4. PLoS genetics 15 (7) (2019)
Carl R Walkley, Benjamin T Kile
Cell death following the loss of ADAR1 mediated A-to-I RNA editing is not effected by the intrinsic apoptosis pathway. Cell death & disease 10 (12) (2019)
Taisuke Nakahama, Yuki Kato, Jung In Kim, Tuangtong Vongpipatana, Yutaka Suzuki, Carl R Walkley, Yukio Kawahara
ADAR1-mediated RNA editing is required for thymic self-tolerance and inhibition of autoimmunity. EMBO reports 19 (12) (2018)
Sally K Martin, Stephen Fitter, Nadia El Khawanky, Randall H Grose, Carl R Walkley, Louise E Purton, Markus A Ruegg, Michael N Hall, Stan Gronthos, Andrew C W Zannettino
mTORC1 plays an important role in osteoblastic regulation of B-lymphopoiesis. Scientific reports 8 (1) (2018)
Monique F Smeets, Shuh Ying Tan, Jane Jialu Xu, Govardhan Anande, Ashwin Unnikrishnan, Alistair M Chalk, Scott R Taylor, John E Pimanda, Meaghan Wall, Louise E Purton, Carl R Walkley
Srsf2P95H initiates myeloid bias and myelodysplastic/myeloproliferative syndrome from hemopoietic stem cells. Blood 132 (6) (2018)
Mannu K Walia, Wilson Castillo-Tandazo, Anthony J Mutsaers, Thomas John Martin, Carl R Walkley
Murine models of osteosarcoma: A piece of the translational puzzle. Journal of cellular biochemistry 119 (6) (2018)
Mannu K Walia, Scott Taylor, Patricia W M Ho, T John Martin, Carl R Walkley
Tolerance to sustained activation of the cAMP/Creb pathway activity in osteoblastic cells is enabled by loss of p53. Cell death & disease 9 (9) (2018)
Jacki E Heraud-Farlow, Alistair M Chalk, Sandra E Linder, Qin Li, Scott Taylor, Joshua M White, Lokman Pang, Brian J Liddicoat, Ankita Gupte, Jin Billy Li, Carl R Walkley
Protein recoding by ADAR1-mediated RNA editing is not essential for normal development and homeostasis. Genome biology 18 (1) (2017)
Mannu K Walia, Patricia Mw Ho, Scott Taylor, Alvin Jm Ng, Ankita Gupte, Alistair M Chalk, Andrew Cw Zannettino, T John Martin, Carl R Walkley
Activation of PTHrP-cAMP-CREB1 signaling following p53 loss is essential for osteosarcoma initiation and maintenance. eLife 5 (2016)

Carl R Walkley.css-eqlu8i{font-size:small;padding-left:4px;} (Carl Walkley)

Publication Activity (10 Years)

Top Topics

Top Venues

Carl R Walkley (Carl Walkley)