Simon J R Heales (Simon Heales)

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 16

Top Topics

Replacement Therapy

Cerebral Blood Flow

Positron Emission Tomography

Top Venues

Science translational medicine

Journal of clinical medicine

International journal of molecular sciences

This page only lists publications with an associated author ORCID identifier.

Publications

Sonam Gurung, Oskar Vilhelmsson Timmermand, Dany P Perocheau, Ana Luisa Gil-Martinez, Magdalena Minnion, Loukia Touramanidou, Sherry Fang, Martina Messina, Youssef Khalil, Justyna Spiewak, Abigail R Barber, Richard S Edwards, Patrícia Lipari Pinto, Patrick F Finn, Alex Cavedon, Summar Siddiqui, Lisa Rice, Paolo G V Martini, Deborah Ridout, Wendy Heywood, Ian Hargreaves, Simon J R Heales, Philippa B Mills, Simon N Waddington, Paul Gissen, Simon Eaton, Mina Ryten, Martin Feelisch, Andrea Frassetto, Timothy H Witney, Julien Baruteau
mRNA therapy corrects defective glutathione metabolism and restores ureagenesis in preclinical argininosuccinic aciduria. Science translational medicine 16 (729) (2024)
Sonam Gurung, Oskar Vilhelmsson Timmermand, Dany P Perocheau, Ana Luisa Gil-Martinez, Magdalena Minnion, Loukia Touramanidou, Sherry Fang, Martina Messina, Youssef Khalil, Justyna Spiewak, Abigail R Barber, Richard S Edwards, Patrícia Lipari Pinto, Patrick F Finn, Alex Cavedon, Summar Siddiqui, Lisa Rice, Paolo G V Martini, Deborah Ridout, Wendy Heywood, Ian Hargreaves, Simon J R Heales, Philippa B Mills, Simon N Waddington, Paul Gissen, Simon Eaton, Mina Ryten, Martin Feelisch, Andrea Frassetto, Timothy H Witney, Julien Baruteau
mRNA therapy corrects defective glutathione metabolism and restores ureagenesis in preclinical argininosuccinic aciduria. Science translational medicine 16 (729) (2024)
Rohit Hirachan, Alistair Horman, Derek Burke, Simon J R Heales
Evaluation, in a highly specialised enzyme laboratory, of a digital microfluidics platform for rapid assessment of lysosomal enzyme activity in dried blood spots. JIMD reports 65 (2) (2024)
Sonam Gurung, Oskar Vilhelmsson Timmermand, Dany P Perocheau, Ana Luisa Gil-Martinez, Magdalena Minnion, Loukia Touramanidou, Sherry Fang, Martina Messina, Youssef Khalil, Justyna Spiewak, Abigail R Barber, Richard S Edwards, Patrícia Lipari Pinto, Patrick F Finn, Alex Cavedon, Summar Siddiqui, Lisa Rice, Paolo G V Martini, Deborah Ridout, Wendy Heywood, Ian Hargreaves, Simon J R Heales, Philippa B Mills, Simon N Waddington, Paul Gissen, Simon Eaton, Mina Ryten, Martin Feelisch, Andrea Frassetto, Timothy H Witney, Julien Baruteau
mRNA therapy corrects defective glutathione metabolism and restores ureagenesis in preclinical argininosuccinic aciduria. Science translational medicine 16 (729) (2024)
Sonam Gurung, Oskar Vilhelmsson Timmermand, Dany P Perocheau, Ana Luisa Gil-Martinez, Magdalena Minnion, Loukia Touramanidou, Sherry Fang, Martina Messina, Youssef Khalil, Justyna Spiewak, Abigail R Barber, Richard S Edwards, Patrícia Lipari Pinto, Patrick F Finn, Alex Cavedon, Summar Siddiqui, Lisa Rice, Paolo G V Martini, Deborah Ridout, Wendy Heywood, Ian Hargreaves, Simon J R Heales, Philippa B Mills, Simon N Waddington, Paul Gissen, Simon Eaton, Mina Ryten, Martin Feelisch, Andrea Frassetto, Timothy H Witney, Julien Baruteau
mRNA therapy corrects defective glutathione metabolism and restores ureagenesis in preclinical argininosuccinic aciduria. Science translational medicine 16 (729) (2024)
Sonam Gurung, Oskar Vilhelmsson Timmermand, Dany P Perocheau, Ana Luisa Gil-Martinez, Magdalena Minnion, Loukia Touramanidou, Sherry Fang, Martina Messina, Youssef Khalil, Justyna Spiewak, Abigail R Barber, Richard S Edwards, Patrícia Lipari Pinto, Patrick F Finn, Alex Cavedon, Summar Siddiqui, Lisa Rice, Paolo G V Martini, Deborah Ridout, Wendy Heywood, Ian Hargreaves, Simon J R Heales, Philippa B Mills, Simon N Waddington, Paul Gissen, Simon Eaton, Mina Ryten, Martin Feelisch, Andrea Frassetto, Timothy H Witney, Julien Baruteau
mRNA therapy corrects defective glutathione metabolism and restores ureagenesis in preclinical argininosuccinic aciduria. Science translational medicine 16 (729) (2024)
Sonam Gurung, Oskar Vilhelmsson Timmermand, Dany P Perocheau, Ana Luisa Gil-Martinez, Magdalena Minnion, Loukia Touramanidou, Sherry Fang, Martina Messina, Youssef Khalil, Justyna Spiewak, Abigail R Barber, Richard S Edwards, Patrícia Lipari Pinto, Patrick F Finn, Alex Cavedon, Summar Siddiqui, Lisa Rice, Paolo G V Martini, Deborah Ridout, Wendy Heywood, Ian Hargreaves, Simon J R Heales, Philippa B Mills, Simon N Waddington, Paul Gissen, Simon Eaton, Mina Ryten, Martin Feelisch, Andrea Frassetto, Timothy H Witney, Julien Baruteau
mRNA therapy corrects defective glutathione metabolism and restores ureagenesis in preclinical argininosuccinic aciduria. Science translational medicine 16 (729) (2024)
Sonam Gurung, Oskar Vilhelmsson Timmermand, Dany P Perocheau, Ana Luisa Gil-Martinez, Magdalena Minnion, Loukia Touramanidou, Sherry Fang, Martina Messina, Youssef Khalil, Justyna Spiewak, Abigail R Barber, Richard S Edwards, Patrícia Lipari Pinto, Patrick F Finn, Alex Cavedon, Summar Siddiqui, Lisa Rice, Paolo G V Martini, Deborah Ridout, Wendy Heywood, Ian Hargreaves, Simon J R Heales, Philippa B Mills, Simon N Waddington, Paul Gissen, Simon Eaton, Mina Ryten, Martin Feelisch, Andrea Frassetto, Timothy H Witney, Julien Baruteau
mRNA therapy corrects defective glutathione metabolism and restores ureagenesis in preclinical argininosuccinic aciduria. Science translational medicine 16 (729) (2024)
Rohit Hirachan, Alistair Horman, Derek Burke, Simon J R Heales
Evaluation, in a highly specialised enzyme laboratory, of a digital microfluidics platform for rapid assessment of lysosomal enzyme activity in dried blood spots. JIMD reports 65 (2) (2024)
Sonam Gurung, Oskar Vilhelmsson Timmermand, Dany P Perocheau, Ana Luisa Gil-Martinez, Magdalena Minnion, Loukia Touramanidou, Sherry Fang, Martina Messina, Youssef Khalil, Justyna Spiewak, Abigail R Barber, Richard S Edwards, Patrícia Lipari Pinto, Patrick F Finn, Alex Cavedon, Summar Siddiqui, Lisa Rice, Paolo G V Martini, Deborah Ridout, Wendy Heywood, Ian Hargreaves, Simon J R Heales, Philippa B Mills, Simon N Waddington, Paul Gissen, Simon Eaton, Mina Ryten, Martin Feelisch, Andrea Frassetto, Timothy H Witney, Julien Baruteau
mRNA therapy corrects defective glutathione metabolism and restores ureagenesis in preclinical argininosuccinic aciduria. Science translational medicine 16 (729) (2024)
Christina E Toomey, Wendy E Heywood, James R Evans, Joanne Lachica, Sarah N Pressey, Sandrine C Foti, Mesfer Al Shahrani, Karishma D'Sa, Iain P Hargreaves, Simon J R Heales, Michael Orford, Claire Troakes, Johannes Attems, Ellen Gelpi, Miklos Palkovits, Tammaryn Lashley, Steve M Gentleman, Tamas Revesz, Kevin A Mills, Sonia Gandhi
Mitochondrial dysfunction is a key pathological driver of early stage Parkinson's. Acta neuropathologica communications 10 (1) (2022)
Robert A Heaton, Simon J R Heales, Khalid Rahman, Darren W Sexton, Iain Hargreaves
The Effect of Cellular Coenzyme Q10 Deficiency on Lysosomal Acidification. Journal of clinical medicine 9 (6) (2020)
Luke Wainwright, Iain P Hargreaves, Ana R Georgian, Charles Turner, R Neil Dalton, N Joan Abbott, Simon J R Heales, Jane E Preston
CoQ10 Deficient Endothelial Cell Culture Model for the Investigation of CoQ10 Blood-Brain Barrier Transport. Journal of clinical medicine 9 (10) (2020)
Stefan Krywawych, Maureen Cleary, Mel McSweeney, Simon J R Heales
Earwax: A potentially useful medium to identify inborn errors of metabolism? JIMD reports 52 (1) (2020)
Xiulin Ng, Mona Sadeghian, Simon J R Heales, Iain P Hargreaves
Assessment of Mitochondrial Dysfunction in Experimental Autoimmune Encephalomyelitis (EAE) Models of Multiple Sclerosis. International journal of molecular sciences 20 (20) (2019)
Jonathan R A Lambert, Steven J Howe, Ahad A Rahim, Derek G Burke, Simon J R Heales
Inhibition of Mitochondrial Complex I Impairs Release of α-Galactosidase by Jurkat Cells. International journal of molecular sciences 20 (18) (2019)