Steven T Staben

ORCID

Publication Activity (10 Years)

Years Active: 2018-2022
Publications (10 Years): 7

Top Venues

Journal of medicinal chemistry

Journal of the American Chemical Society

This page only lists publications with an associated author ORCID identifier.

Publications

Christopher McBride, Lynnie Trzoss, Davide Povero, Milos Lazic, Geza Ambrus-Aikelin, Angelina Santini, Rama Pranadinata, Gretchen Bain, Ryan Stansfield, Jeffrey A Stafford, James Veal, Ryan Takahashi, Justin Ly, Shu Chen, Liling Liu, Marika Nespi, Robert Blake, Arna Katewa, Tracy Kleinheinz, Swathi Sujatha-Bhaskar, Nandhini Ramamoorthi, Jessica Sims, Brent McKenzie, Mark Chen, Mark Ultsch, Matthew Johnson, Jeremy M Murray, Claudio Ciferri, Steven T Staben, Michael J Townsend, Craig E Stivala
Overcoming Preclinical Safety Obstacles to Discover ( S )- N -((1,2,3,5,6,7-Hexahydro- s -indacen-4-yl)carbamoyl)-6-(methylamino)-6,7-dihydro-5 H -pyrazolo[5,1- b ][1,3]oxazine-3-sulfonamide (GDC-2394): A Potent and Selective NLRP3 Inhibitor. Journal of medicinal chemistry 65 (21) (2022)
Emily J Hanan, Marie-Gabrielle Braun, Robert A Heald, Calum MacLeod, Connie Chan, Saundra Clausen, Kyle A Edgar, Charles Eigenbrot, Richard Elliott, Nicholas Endres, Lori S Friedman, Emily Gogol, Xiao-Hui Gu, Rebecca Hong Thibodeau, Philip S Jackson, James R Kiefer, Jamie D Knight, Michelle Nannini, Raman Narukulla, Amanda Pace, Jodie Pang, Hans E Purkey, Laurent Salphati, Deepak Sampath, Stephen Schmidt, Steve Sideris, Kyung Song, Swathi Sujatha-Bhaskar, Mark Ultsch, Heidi Wallweber, Jianfeng Xin, SiewKuen Yeap, Amy Young, Yu Zhong, Steven T Staben
Discovery of GDC-0077 (Inavolisib), a Highly Selective Inhibitor and Degrader of Mutant PI3Kα. Journal of medicinal chemistry (2022)
Willem den Besten, Kshitij Verma, Sayumi Yamazoe, Nicole Blaquiere, Wilson Phung, Anita Izrael-Tomasevic, Melinda M Mulvihill, Elizabeth Helgason, Sumit Prakash, Tatiana Goncharov, Domagoj Vucic, Erin C Dueber, Wayne J Fairbrother, Ingrid Wertz, Kebing Yu, Steven T Staben
Primary Amine Tethered Small Molecules Promote the Degradation of X-Linked Inhibitor of Apoptosis Protein. Journal of the American Chemical Society 143 (28) (2021)
Emily J Hanan, Jun Liang, Xiaojing Wang, Robert A Blake, Nicole Blaquiere, Steven T Staben
Monomeric Targeted Protein Degraders. Journal of medicinal chemistry 63 (20) (2020)
Nicole Blaquiere, Elisia Villemure, Steven T Staben
Medicinal Chemistry of Inhibiting RING-Type E3 Ubiquitin Ligases. Journal of medicinal chemistry 63 (15) (2020)
Sayumi Yamazoe, Jeffrey Tom, Yue Fu, Wenqiong Wu, Liang Zeng, Changlei Sun, Qi Liu, Jie Lin, Kui Lin, Wayne J Fairbrother, Steven T Staben
Heterobifunctional Molecules Induce Dephosphorylation of Kinases-A Proof of Concept Study. Journal of medicinal chemistry 63 (6) (2020)
Nicole Blaquiere, Georgette M Castanedo, Jason D Burch, Leonid M Berezhkovskiy, Hans Brightbill, Suzanne Brown, Connie Chan, Po-Chang Chiang, James J Crawford, Teresa Dong, Peter Fan, Jianwen Feng, Nico Ghilardi, Robert Godemann, Emily Gogol, Alice Grabbe, Alison J Hole, Baihua Hu, Sarah G Hymowitz, Moulay Hicham Alaoui Ismaili, Hoa Le, Patrick Lee, Wyne Lee, Xingyu Lin, Ning Liu, Paul A McEwan, Brent McKenzie, Hernani L Silvestre, Eric Suto, Swathi Sujatha-Bhaskar, Guosheng Wu, Lawren C Wu, Yamin Zhang, Zoe Zhong, Steven T Staben
Scaffold-Hopping Approach To Discover Potent, Selective, and Efficacious Inhibitors of NF-κB Inducing Kinase. Journal of medicinal chemistry 61 (15) (2018)

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Publication Activity (10 Years)

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Steven T Staben