James J Crawford

Scopus Author ID Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2018-2023
Publications (10 Years): 14

Top Venues

ACS medicinal chemistry letters

Chemical science

Nature communications

Journal of medicinal chemistry

This page only lists publications with an associated author ORCID identifier.

Publications

Ruth Dorel, Alice R Wong, James J Crawford
Trust Your Gut: Strategies and Tactics for Intestinally Restricted Drugs. ACS medicinal chemistry letters 14 (3) (2023)
Catherine L A Salvini, Benoit Darlot, Jack Davison, Mathew P Martin, Susan J Tudhope, Shannon Turberville, Akane Kawamura, Martin E M Noble, Stephen R Wedge, James J Crawford, Michael J Waring
Fragment expansion with NUDELs - poised DNA-encoded libraries. Chemical science 14 (31) (2023)
Michael F T Koehler, Yi-Chen Chen, Yongsheng Chen, Yuan Chen, James J Crawford, Matthew R Durk, Keira Garland, Emily J Hanan, Robert I Higuchi, Huiyong Hu, Cuong Q Ly, Prasuna G Paraselli, Tucker C Roberts, Jacob B Schwarz, Peter A Smith, Zhiyong Yu, Christopher E Heise
Lipid Tales: Optimizing Arylomycin Membrane Anchors. ACS medicinal chemistry letters 14 (11) (2023)
Thijs J Hagenbeek, Jason R Zbieg, Marc Hafner, Rana Mroue, Jennifer A Lacap, Nicole M Sodir, Cameron L Noland, Shervin Afghani, Ayush Kishore, Kamakoti P Bhat, Xiaosai Yao, Stephen Schmidt, Saundra Clausen, Micah Steffek, Wendy Lee, Paul Beroza, Scott Martin, Eva Lin, Rina Fong, Paola Di Lello, Marta H Kubala, Michelle N-Y Yang, Jeffrey T Lau, Emily Chan, Alfonso Arrazate, Le An, Elizabeth Levy, Maria N Lorenzo, Ho-June Lee, Trang H Pham, Zora Modrusan, Richard Zang, Yi-Chen Chen, Michal Kabza, Musaddeque Ahmed, Jason Li, Matthew T Chang, Danilo Maddalo, Marie Evangelista, Xin Ye, James J Crawford, Anwesha Dey
An allosteric pan-TEAD inhibitor blocks oncogenic YAP/TAZ signaling and overcomes KRAS G12C inhibitor resistance. Nature cancer (2023)
Yong Wang, Wendy Lee, Yi-Chen Chen, Yuhui Zhou, Emile Plise, Madyson Migliozzi, James J Crawford
Turning the Other Cheek: Influence of the cis -Tetrafluorocyclohexyl Motif on Physicochemical and Metabolic Properties. ACS medicinal chemistry letters 13 (9) (2022)
Paul Beroza, James J Crawford, Oleg Ganichkin, Leo Gendelev, Seth F Harris, Raphael Klein, Anh Miu, Stefan Steinbacher, Franca-Maria Klingler, Christian Lemmen
Chemical space docking enables large-scale structure-based virtual screening to discover ROCK1 kinase inhibitors. Nature communications 13 (1) (2022)
Matthew L Landry, Richard Trager, Fabio Broccatelli, James J Crawford
When Cofactors Aren't X Factors: Functional Groups That Are Labile in Human Liver Microsomes in the Absence of NADPH. ACS medicinal chemistry letters 13 (4) (2022)
James H Hunter, Matthew J Anderson, Isaline F S F Castan, Jessica S Graham, Catherine L A Salvini, Harriet A Stanway-Gordon, James J Crawford, Andrew Madin, Garry Pairaudeau, Michael J Waring
Highly efficient on-DNA amide couplings promoted by micelle forming surfactants for the synthesis of DNA encoded libraries. Chemical science 12 (27) (2021)
Chenghong Zhang, James J Crawford, Matthew L Landry, Huifen Chen, Jane R Kenny, S Cyrus Khojasteh, Wendy Lee, Shuguang Ma, Wendy B Young
Strategies to Mitigate the Bioactivation of Aryl Amines. Chemical research in toxicology 33 (7) (2020)
Cesar A Corzo, Eugene Varfolomeev, A Francesca Setiadi, Ross Francis, Sha Klabunde, Kate Senger, Swathi Sujatha-Bhaskar, Joy Drobnick, Steven Do, Eric Suto, Zhiyu Huang, Jeffrey Eastham-Anderson, Arna Katewa, Jodie Pang, Melanie Domeyer, Christopher Dela Cruz, Andres Paler-Martinez, Vivian Wing Chong Lau, Azadeh Hadadianpour, Vladimir Ramirez-Carrozzi, Yonglian Sun, Katherine Bao, Daqi Xu, Emily Hunley, Hans D Brightbill, Søren Warming, Merone Roose-Girma, Alfred Wong, Lucinda Tam, Claire L Emson, James J Crawford, Wendy B Young, Rajita Pappu, Brent S McKenzie, Vida Asghari, Domagoj Vucic, Jason A Hackney, Cary D Austin, Ho-June Lee, Annemarie N Lekkerkerker, Nico Ghilardi, Marian C Bryan, James R Kiefer, Michael J Townsend, Ali A Zarrin
The kinase IRAK4 promotes endosomal TLR and immune complex signaling in B cells and plasmacytoid dendritic cells. Science signaling 13 (634) (2020)
James J Crawford, Adam R Johnson, Dinah L Misner, Lisa D Belmont, Georgette M Castanedo, Regina Choy, Melis Coraggio, Liming Dong, Charles Eigenbrot, Rebecca Erickson, Nico Ghilardi, Jonathan Hau, Arna Katewa, Pawan Bir Kohli, Wendy Lee, Joseph W Lubach, Brent S McKenzie, Daniel F Ortwine, Leah Schutt, Suzanne Tay, BinQing Wei, Karin Reif, Lichuan Liu, Harvey Wong, Xiaojing Wang
Discovery of GDC-0853: A Potent, Selective, and Noncovalent Bruton's Tyrosine Kinase Inhibitor in Early Clinical Development. Journal of medicinal chemistry 61 (6) (2018)
Hans D Brightbill, Eric Suto, Nicole Blaquiere, Nandhini Ramamoorthi, Swathi Sujatha-Bhaskar, Emily B Gogol, Georgette M Castanedo, Benjamin T Jackson, Youngsu C Kwon, Susan Haller, Justin Lesch, Karin Bents, Christine Everett, Pawan Bir Kohli, Sandra Linge, Laura Christian, Kathy Barrett, Allan Jaochico, Leonid M Berezhkovskiy, Peter W Fan, Zora Modrusan, Kelli Veliz, Michael J Townsend, Jason DeVoss, Adam R Johnson, Robert Godemann, Wyne P Lee, Cary D Austin, Brent S McKenzie, Jason A Hackney, James J Crawford, Steven T Staben, Moulay H Alaoui Ismaili, Lawren C Wu, Nico Ghilardi
NF-κB inducing kinase is a therapeutic target for systemic lupus erythematosus. Nature communications 9 (1) (2018)
James J Crawford, Sarah M Bronner, Jason R Zbieg
Hippo pathway inhibition by blocking the YAP/TAZ-TEAD interface: a patent review. Expert opinion on therapeutic patents 28 (12) (2018)
Nicole Blaquiere, Georgette M Castanedo, Jason D Burch, Leonid M Berezhkovskiy, Hans Brightbill, Suzanne Brown, Connie Chan, Po-Chang Chiang, James J Crawford, Teresa Dong, Peter Fan, Jianwen Feng, Nico Ghilardi, Robert Godemann, Emily Gogol, Alice Grabbe, Alison J Hole, Baihua Hu, Sarah G Hymowitz, Moulay Hicham Alaoui Ismaili, Hoa Le, Patrick Lee, Wyne Lee, Xingyu Lin, Ning Liu, Paul A McEwan, Brent McKenzie, Hernani L Silvestre, Eric Suto, Swathi Sujatha-Bhaskar, Guosheng Wu, Lawren C Wu, Yamin Zhang, Zoe Zhong, Steven T Staben
Scaffold-Hopping Approach To Discover Potent, Selective, and Efficacious Inhibitors of NF-κB Inducing Kinase. Journal of medicinal chemistry 61 (15) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

James J Crawford