Thomas J Gardella

ORCID

Publication Activity (10 Years)

Years Active: 2019-2023
Publications (10 Years): 10

Top Venues

JBMR plus

Nature chemical biology

Endocrinology

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Massachusetts General Hospital

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Massachusetts General Hospital Jun 11 1988

United States

Associate Professor :: Medicine

Publications

Ignacio Portales-Castillo, Thomas Dean, Ross W Cheloha, Brendan A Creemer, Jean-Pierre Vilardaga, Sofya Savransky, Ashok Khatri, Harald Jüppner, Thomas J Gardella
Altered Signaling and Desensitization Responses in PTH1R Mutants Associated with Eiken Syndrome. Communications biology 6 (1) (2023)
Monica Reyes, Damla Firat, Patrick Hanna, Mohd Khan, Michael Bruce, Maria Shvedova, Tatsuya Kobayashi, Ernestina Schipani, Thomas J Gardella, Harald Jüppner
Substantially Delayed Maturation of Growth Plate Chondrocytes in "Humanized" PTH1R Mice with the H223R Mutation of Jansen's Disease. JBMR plus 7 (10) (2023)
Shivani Sachdev, Brendan A Creemer, Thomas J Gardella, Ross W Cheloha
Highly biased agonism for GPCR ligands via nanobody tethering. bioRxiv : the preprint server for biology (2023)
Ignacio Portales-Castillo, Thomas Dean, Ashok Khatri, Harald Jüppner, Thomas J Gardella
Functional Properties of Two Distinct PTH1R Mutants Associated With Either Skeletal Defects or Pseudohypoparathyroidism. JBMR plus 6 (6) (2022)
Eileen J Daley, Sung-Hee Yoon, Monica Reyes, Michael Bruce, Daniel J Brooks, Mary Bouxsein, John T Potts, Henry M Kronenberg, Marc N Wein, Beate Lanske, Harald Jüppner, Thomas J Gardella
Actions of Parathyroid Hormone Ligand Analogues in Humanized PTH1R Knockin Mice. Endocrinology 163 (7) (2022)
Tadatoshi Sato, Shiv Verma, Ashok Khatri, Thomas Dean, Olga Goransson, Thomas J Gardella, Marc N Wein
Comparable Initial Engagement of Intracellular Signaling Pathways by Parathyroid Hormone Receptor Ligands Teriparatide, Abaloparatide, and Long-Acting PTH. JBMR plus 5 (5) (2021)
Ieva Sutkeviciute, Ji Young Lee, Alex D White, Christian Santa Maria, Karina A Peña, Sofya Savransky, Pemra Doruker, Hongchun Li, Saifei Lei, Burak Kaynak, Chia-Ling Tu, Lisa J Clark, Subramaniam Sanker, Thomas J Gardella, Wenhan Chang, Ivet Bahar, Jean-Pierre Vilardaga
Precise druggability of the PTH type 1 receptor. Nature chemical biology 18 (3) (2021)
Hiroshi Noda, Makoto Okazaki, Eri Joyashiki, Tatsuya Tamura, Yoshiki Kawabe, Ashok Khatri, Harald Jueppner, John T Potts, Thomas J Gardella, Masaru Shimizu
Optimization of PTH/PTHrP Hybrid Peptides to Derive a Long-Acting PTH Analog (LA-PTH). JBMR plus 4 (7) (2020)
Lisa J Clark, James Michael Krieger, Alex D White, Vasyl Bondarenko, Saifei Lei, Fei Fang, Ji Young Lee, Pemra Doruker, Thore Böttke, Frederic Jean-Alphonse, Pei Tang, Thomas J Gardella, Kunhong Xiao, Ieva Sutkeviciute, Irene Coin, Ivet Bahar, Jean-Pierre Vilardaga
Allosteric interactions in the parathyroid hormone GPCR-arrestin complex formation. Nature chemical biology 16 (10) (2020)
Hiroshi Noda, Jun Guo, Ashok Khatri, Thomas Dean, Monica Reyes, Michael Armanini, Daniel J Brooks, Janaina S Martins, Ernestina Schipani, Mary L Bouxsein, Marie B Demay, John T Potts, Harald Jüppner, Thomas J Gardella
An Inverse Agonist Ligand of the PTH Receptor Partially Rescues Skeletal Defects in a Mouse Model of Jansen's Metaphyseal Chondrodysplasia. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 35 (3) (2019)

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Publication Activity (10 Years)

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Thomas J Gardella