Jean-Pierre Vilardaga

Scopus Author ID Pitt ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 14

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

Nature chemical biology

Endocrine reviews

The Journal of biological chemistry

University of Pittsburgh

Free University Brussels (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Pittsburgh Apr 01 2008

United States

Professor (tenure) :: Pharmacology & Chemical Biology

Harvard Medical School

United States

Assistant Professor :: Endocrine Unit

Institute for Pharmacology & Toxicology Nov 01 1998 - Nov 01 2005

Germany

Postdoc/Instructor :: Pharmacology

UCSF Feb 01 1996 - Oct 01 1998

United States

Postdoc :: Endocrine Research Unit Veterans’ Affairs Medical Center and Departments of Medicine and Physiology

Education History

Free University Brussels

Belgium

PHD :: Molecular Pharmacology

Free University of Brussels Oct 01 1988 - Jan 01 1991

Belgium

MSC :: Molecular Biology

University de Nice

France

MSC :: Molecular Chemistry

Universiy of Nice

France

BSC :: Chemistry

University of Nice

France

BSC :: Physics

Publications

Ignacio Portales-Castillo, Thomas Dean, Ross W Cheloha, Brendan A Creemer, Jean-Pierre Vilardaga, Sofya Savransky, Ashok Khatri, Harald Jüppner, Thomas J Gardella
Altered Signaling and Desensitization Responses in PTH1R Mutants Associated with Eiken Syndrome. Communications biology 6 (1) (2023)
Jean-Pierre Vilardaga, Lisa J Clark, Alex D White, Ieva Sutkeviciute, Ji Young Lee, Ivet Bahar
Molecular Mechanisms of PTH/PTHrP class B GPCR Signaling and Pharmacological Implications. Endocrine reviews (2022)
Jean-Pierre Vilardaga, Lisa J Clark, Alex D White, Ieva Sutkeviciute, Ji Young Lee, Ivet Bahar
Molecular Mechanisms of PTH/PTHrP class B GPCR Signaling and Pharmacological Implications. Endocrine reviews (2022)
Alex D White, Karina A Peña, Lisa J Clark, Christian Santa Maria, Shi Liu, Frédéric G Jean-Alphonse, Ji Young Lee, Saifei Lei, Zhiqiang Cheng, Chia-Ling Tu, Fei Fang, Nicholas Szeto, Thomas J Gardella, Kunhong Xiao, Samuel H Gellman, Ivet Bahar, Ieva Sutkeviciute, Wenhan Chang, Jean-Pierre Vilardaga
Spatial bias in cAMP generation determines biological responses to PTH type 1 receptor activation. Science signaling 14 (703) (2021)
Ieva Sutkeviciute, Ji Young Lee, Alex D White, Christian Santa Maria, Karina A Peña, Sofya Savransky, Pemra Doruker, Hongchun Li, Saifei Lei, Burak Kaynak, Chia-Ling Tu, Lisa J Clark, Subramaniam Sanker, Thomas J Gardella, Wenhan Chang, Ivet Bahar, Jean-Pierre Vilardaga
Precise druggability of the PTH type 1 receptor. Nature chemical biology 18 (3) (2021)
Wenhan Chang, Chia-Ling Tu, Frederic G Jean-Alphonse, Amanda Herberger, Zhiqiang Cheng, Jenna Hwong, Hanson Ho, Alfred Li, Dawei Wang, Hongda Liu, Alex D White, Insoo Suh, Wen Shen, Quan-Yang Duh, Elham Khanafshar, Dolores M Shoback, Kunhong Xiao, Jean-Pierre Vilardaga
PTH hypersecretion triggered by a GABAB1 and Ca2+-sensing receptor heterocomplex in hyperparathyroidism. Nature metabolism 2 (3) (2020)
Lisa J Clark, James Michael Krieger, Alex D White, Vasyl Bondarenko, Saifei Lei, Fei Fang, Ji Young Lee, Pemra Doruker, Thore Böttke, Frederic Jean-Alphonse, Pei Tang, Thomas J Gardella, Kunhong Xiao, Ieva Sutkeviciute, Irene Coin, Ivet Bahar, Jean-Pierre Vilardaga
Allosteric interactions in the parathyroid hormone GPCR-arrestin complex formation. Nature chemical biology 16 (10) (2020)
Alex D White, Frédéric G Jean-Alphonse, Fei Fang, Karina A Peña, Shi Liu, Gabriele M König, Asuka Inoue, Despoina Aslanoglou, Samuel H Gellman, Evi Kostenis, Kunhong Xiao, Jean-Pierre Vilardaga
Gq/11-dependent regulation of endosomal cAMP generation by parathyroid hormone class B GPCR. Proceedings of the National Academy of Sciences of the United States of America 117 (13) (2020)
Ieva Sutkeviciute, Jean-Pierre Vilardaga
Structural insights into emergent signaling modes of G protein-coupled receptors. The Journal of biological chemistry 295 (33) (2020)
Alex D White, Fei Fang, Frédéric G Jean-Alphonse, Lisa J Clark, Hyun-Jung An, Hongda Liu, Yang Zhao, Shelley L Reynolds, Sihoon Lee, Kunhong Xiao, Ieva Sutkeviciute, Jean-Pierre Vilardaga
Ca2+ allostery in PTH-receptor signaling. Proceedings of the National Academy of Sciences of the United States of America 116 (8) (2019)
Shi Liu, Frederic G Jean-Alphonse, Alex D White, Denise Wootten, Patrick M Sexton, Thomas J Gardella, Jean-Pierre Vilardaga, Samuel H Gellman
Use of Backbone Modification To Enlarge the Spatiotemporal Diversity of Parathyroid Hormone Receptor-1 Signaling via Biased Agonism. Journal of the American Chemical Society 141 (37) (2019)
Li-Hua Zhao, Shanshan Ma, Ieva Sutkeviciute, Dan-Dan Shen, X Edward Zhou, Parker W de Waal, Chen-Yao Li, Yanyong Kang, Lisa J Clark, Frédéric G Jean-Alphonse, Alex D White, Dehua Yang, Antao Dai, Xiaoqing Cai, Jian Chen, Cong Li, Yi Jiang, Tomoyuki Watanabe, Thomas J Gardella, Karsten Melcher, Ming-Wei Wang, Jean-Pierre Vilardaga, H Eric Xu, Yan Zhang
Structure and dynamics of the active human parathyroid hormone receptor-1. Science (New York, N.Y.) 364 (6436) (2019)
Yalikun Suofu, Diane L Carlisle, Jean-Pierre Vilardaga, Robert M Friedlander
Reply to Ahluwalia et al.: Contributions of melatonin receptors are tissue-dependent. Proceedings of the National Academy of Sciences of the United States of America 115 (9) (2018)
Yalikun Suofu, Wei Li, Frédéric G Jean-Alphonse, Jiaoying Jia, Nicolas K Khattar, Jiatong Li, Sergei V Baranov, Daniela Leronni, Amanda C Mihalik, Yanqing He, Erika Cecon, Vanessa L Wehbi, JinHo Kim, Brianna E Heath, Oxana V Baranova, Xiaomin Wang, Matthew J Gable, Eric S Kretz, Giulietta Di Benedetto, Timothy R Lezon, Lisa M Ferrando, Timothy M Larkin, Mara Sullivan, Svitlana Yablonska, Jingjing Wang, M Beth Minnigh, Gérald Guillaumet, Franck Suzenet, Robert Mark Richardson, Samuel M Poloyac, Donna B Stolz, Ralf Jockers, Paula A Witt-Enderby, Diane L Carlisle, Jean-Pierre Vilardaga, Robert M Friedlander
Dual role of mitochondria in producing melatonin and driving GPCR signaling to block cytochrome c release. Proceedings of the National Academy of Sciences of the United States of America 114 (38) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Jean-Pierre Vilardaga