Thomas J Simpson

Publication Activity (10 Years)

Years Active: 2015-2023
Publications (10 Years): 15

Top Topics

Methicillin Resistant Staphylococcus Aureus

Top Venues

Chemical science

Angewandte Chemie (International ed. in English)

Angewandte Chemie (Weinheim an der Bergstrasse, Germany)

Natural product reports

This page only lists publications with an associated author ORCID identifier.

Publications

Ashley J Winter, R Nisha Khanizeman, Abigail M C Barker-Mountford, Andrew J Devine, Luoyi Wang, Zhongshu Song, Jonathan A Davies, Paul R Race, Christopher Williams, Thomas J Simpson, Christine L Willis, Matthew P Crump
Structure and Function of the α-Hydroxylation Bimodule of the Mupirocin Polyketide Synthase. Angewandte Chemie (Weinheim an der Bergstrasse, Germany) 135 (47) (2023)
Ashley J Winter, R Nisha Khanizeman, Abigail M C Barker-Mountford, Andrew J Devine, Luoyi Wang, Zhongshu Song, Jonathan A Davies, Paul R Race, Christopher Williams, Thomas J Simpson, Christine L Willis, Matthew P Crump
Structure and Function of the α-Hydroxylation Bimodule of the Mupirocin Polyketide Synthase. Angewandte Chemie (Weinheim an der Bergstrasse, Germany) 135 (47) (2023)
Kate M J de Mattos-Shipley, Thomas J Simpson
The 'emodin family' of fungal natural products-amalgamating a century of research with recent genomics-based advances. Natural product reports (2022)
Luoyi Wang, Zhongshu Song, Paul R Race, James Spencer, Thomas J Simpson, Matthew P Crump, Christine L Willis
Mixing and matching genes of marine and terrestrial origin in the biosynthesis of the mupirocin antibiotics. Chemical science 11 (20) (2020)
Christopher D Fage, Thomas Lathouwers, Michiel Vanmeert, Ling-Jie Gao, Kristof Vrancken, Eveline-Marie Lammens, Angus N M Weir, Ruben Degroote, Harry Cuppens, Simone Kosol, Thomas J Simpson, Matthew P Crump, Christine L Willis, Piet Herdewijn, Eveline Lescrinier, Rob Lavigne, Jozef Anné, Joleen Masschelein
The Kalimantacin Polyketide Antibiotics Inhibit Fatty Acid Biosynthesis in Staphylococcus aureus by Targeting the Enoyl-Acyl Carrier Protein Binding Site of FabI. Angewandte Chemie (International ed. in English) 59 (26) (2020)
Kate M J de Mattos-Shipley, Catherine E Spencer, Claudio Greco, David M Heard, Daniel E O'Flynn, Trong T Dao, Zhongshu Song, Nicholas P Mulholland, Jason L Vincent, Thomas J Simpson, Russell J Cox, Andrew M Bailey, Christine L Willis
Uncovering biosynthetic relationships between antifungal nonadrides and octadrides. Chemical science 11 (42) (2020)
Paul D Walker, Christopher Williams, Angus N M Weir, Luoyi Wang, John Crosby, Paul R Race, Thomas J Simpson, Christine L Willis, Matthew P Crump
Control of β-Branching in Kalimantacin Biosynthesis: Application of 13 C NMR to Polyketide Programming. Angewandte Chemie (International ed. in English) 58 (36) (2019)
Claudio Greco, Kate de Mattos-Shipley, Andrew M Bailey, Nicholas P Mulholland, Jason L Vincent, Christine L Willis, Russell J Cox, Thomas J Simpson
Structure revision of cryptosporioptides and determination of the genetic basis for dimeric xanthone biosynthesis in fungi. Chemical science 10 (10) (2019)
Xiao-Long Yang, Steffen Friedrich, Sen Yin, Oliver Piech, Katherine Williams, Thomas J Simpson, Russell J Cox
Molecular basis of methylation and chain-length programming in a fungal iterative highly reducing polyketide synthase. Chemical science 10 (36) (2019)
Kate M J de Mattos-Shipley, Claudio Greco, David M Heard, Gemma Hough, Nicholas P Mulholland, Jason L Vincent, Jason Micklefield, Thomas J Simpson, Christine L Willis, Russell J Cox, Andrew M Bailey
The cycloaspeptides: uncovering a new model for methylated nonribosomal peptide biosynthesis. Chemical science 9 (17) (2018)
Zahida Wasil, Eric Kuhnert, Thomas J Simpson, Russell J Cox
Oryzines A & B, Maleidride Congeners from Aspergillus oryzae and Their Putative Biosynthesis. Journal of fungi (Basel, Switzerland) 4 (3) (2018)
Agnieszka J Szwalbe, Katherine Williams, Zhongshu Song, Kate de Mattos-Shipley, Jason L Vincent, Andrew M Bailey, Christine L Willis, Russell J Cox, Thomas J Simpson
Characterisation of the biosynthetic pathway to agnestins A and B reveals the reductive route to chrysophanol in fungi. Chemical science 10 (1) (2018)
Iain R G Thistlethwaite, Freya M Bull, Chengsen Cui, Paul D Walker, Shu-Shan Gao, Luoyi Wang, Zhongshu Song, Joleen Masschelein, Rob Lavigne, Matthew P Crump, Paul R Race, Thomas J Simpson, Christine L Willis
Elucidation of the relative and absolute stereochemistry of the kalimantacin/batumin antibiotics. Chemical science 8 (9) (2017)
Shu-Shan Gao, Luoyi Wang, Zhongshu Song, Joanne Hothersall, Elton R Stevens, Jack Connolly, Peter J Winn, Russell J Cox, Matthew P Crump, Paul R Race, Christopher M Thomas, Thomas J Simpson, Christine L Willis
Selected Mutations Reveal New Intermediates in the Biosynthesis of Mupirocin and the Thiomarinol Antibiotics. Angewandte Chemie (International ed. in English) 56 (14) (2017)
Xu Dong, Christopher D Bailey, Christopher Williams, John Crosby, Thomas J Simpson, Christine L Willis, Matthew P Crump
Recognition of extended linear and cyclised polyketide mimics by a type II acyl carrier protein. Chemical science 7 (3) (2015)