Christine L Willis (C L Willis)

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 41

Top Venues

Chemical science

Angewandte Chemie (Weinheim an der Bergstrasse, Germany)

Angewandte Chemie (International ed. in English)

Organic & biomolecular chemistry

University of Bristol

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Bristol Dec 01 1981

United Kingdom

Professor of Organic Chemistry :: Chemistry

Publications

Laurence Maschio, Catherine R Back, Jawaher Alnawah, James I Bowen, Samuel T Johns, Sbusisiwe Z Mbatha, Li-Chen Han, Nicholas R Lees, Katja Zorn, James E M Stach, Martin A Hayes, Marc W Van der Kamp, Christopher R Pudney, Steven G Burston, Christine L Willis, Paul R Race
Delineation of the complete reaction cycle of a natural Diels-Alderase. Chemical science 15 (29) (2024)
James I Bowen, Xiaotong Zhong, Kaining Gao, Benjamin Reed, Matthew P Crump, Luoyi Wang, Christine L Willis
Combining total synthesis and genetic engineering to probe dihydropyran formation in ambruticin biosynthesis. Chemical science 15 (14) (2024)
Sbusisiwe Z Mbatha, Catherine R Back, Andrew J Devine, Hannah M Mulliner, Samuel T Johns, Harry Lewin, Kaiman A Cheung, Katja Zorn, James E M Stach, Martin A Hayes, Marc W Van der Kamp, Paul R Race, Christine L Willis
Antibiotic origami: selective formation of spirotetronates in abyssomicin biosynthesis. Chemical science (2024)
James I Bowen, Xiaotong Zhong, Kaining Gao, Benjamin Reed, Matthew P Crump, Luoyi Wang, Christine L Willis
Combining total synthesis and genetic engineering to probe dihydropyran formation in ambruticin biosynthesis. Chemical science 15 (14) (2024)
Laurence Maschio, Catherine R Back, Jawaher Alnawah, James I Bowen, Samuel T Johns, Sbusisiwe Z Mbatha, Li-Chen Han, Nicholas R Lees, Katja Zorn, James E M Stach, Martin A Hayes, Marc W Van der Kamp, Christopher R Pudney, Steven G Burston, Christine L Willis, Paul R Race
Delineation of the complete reaction cycle of a natural Diels-Alderase. Chemical science 15 (29) (2024)
Sbusisiwe Z Mbatha, Catherine R Back, Andrew J Devine, Hannah M Mulliner, Samuel T Johns, Harry Lewin, Kaiman A Cheung, Katja Zorn, James E M Stach, Martin A Hayes, Marc W Van der Kamp, Paul R Race, Christine L Willis
Antibiotic origami: selective formation of spirotetronates in abyssomicin biosynthesis. Chemical science (2024)
Ashley J Winter, R Nisha Khanizeman, Abigail M C Barker-Mountford, Andrew J Devine, Luoyi Wang, Zhongshu Song, Jonathan A Davies, Paul R Race, Christopher Williams, Thomas J Simpson, Christine L Willis, Matthew P Crump
Structure and Function of the α-Hydroxylation Bimodule of the Mupirocin Polyketide Synthase. Angewandte Chemie (Weinheim an der Bergstrasse, Germany) 135 (47) (2023)
Fabrizio Alberti, Khairunisa Khairudin, Jonathan A Davies, Suphattra Sangmalee, Christine L Willis, Gary D Foster, Andrew M Bailey
Biosynthesis of pleuromutilin congeners using an Aspergillus oryzae expression platform. Chemical science 14 (14) (2023)
Ashley J Winter, R Nisha Khanizeman, Abigail M C Barker-Mountford, Andrew J Devine, Luoyi Wang, Zhongshu Song, Jonathan A Davies, Paul R Race, Christopher Williams, Thomas J Simpson, Christine L Willis, Matthew P Crump
Structure and Function of the α-Hydroxylation Bimodule of the Mupirocin Polyketide Synthase. Angewandte Chemie (Weinheim an der Bergstrasse, Germany) 135 (47) (2023)
Katherine Williams, Agnieszka J Szwalbe, Kate M J de Mattos-Shipley, Andrew M Bailey, Russell J Cox, Christine L Willis
Maleidride biosynthesis - construction of dimeric anhydrides - more than just heads or tails. Natural product reports (2022)
Trong-Tuan Dao, Katherine Williams, Kate M J de Mattos-Shipley, Zhongshu Song, Yuiko Takebayashi, Thomas J Simpson, James Spencer, Andrew M Bailey, Christine L Willis
Cladobotric Acids: Metabolites from Cultures of Cladobotryum sp., Semisynthetic Analogues and Antibacterial Activity. Journal of natural products 85 (3) (2022)
Ashley J Winter, Matthew T Rowe, Angus N M Weir, Nahida Akter, Sbusisiwe Z Mbatha, Paul D Walker, Christopher Williams, Zhongshu Song, Paul R Race, Christine L Willis, Matthew P Crump
Programmed Iteration Controls the Assembly of the Nonanoic Acid Side Chain of the Antibiotic Mupirocin. Angewandte Chemie (Weinheim an der Bergstrasse, Germany) 134 (50) (2022)
Andrew J Devine, Alice E Parnell, Catherine R Back, Nicholas R Lees, Samuel T Johns, Ainul Z Zulkepli, Rob Barringer, Katja Zorn, James E M Stach, Matthew P Crump, Martin A Hayes, Marc W Van der Kamp, Paul R Race, Christine L Willis
The Role of Cytochrome P450 AbyV in the Final Stages of Abyssomicin C Biosynthesis. Angewandte Chemie (Weinheim an der Bergstrasse, Germany) 135 (3) (2022)
James I Bowen, Luoyi Wang, Matthew P Crump, Christine L Willis
Synthetic and biosynthetic methods for selective cyclisations of 4,5-epoxy alcohols to tetrahydropyrans. Organic & biomolecular chemistry 20 (6) (2022)
Andrew J Devine, Alice E Parnell, Catherine R Back, Nicholas R Lees, Samuel T Johns, Ainul Z Zulkepli, Rob Barringer, Katja Zorn, James E M Stach, Matthew P Crump, Martin A Hayes, Marc W Van der Kamp, Paul R Race, Christine L Willis
The Role of Cytochrome P450 AbyV in the Final Stages of Abyssomicin C Biosynthesis. Angewandte Chemie (Weinheim an der Bergstrasse, Germany) 135 (3) (2022)
Katherine Williams, Kate M J de Mattos-Shipley, Christine L Willis, Andrew M Bailey
In silico analyses of maleidride biosynthetic gene clusters. Fungal biology and biotechnology 9 (1) (2022)
Ashley J Winter, Matthew T Rowe, Angus N M Weir, Nahida Akter, Sbusisiwe Z Mbatha, Paul D Walker, Christopher Williams, Zhongshu Song, Paul R Race, Christine L Willis, Matthew P Crump
Programmed Iteration Controls the Assembly of the Nonanoic Acid Side Chain of the Antibiotic Mupirocin. Angewandte Chemie (International ed. in English) 61 (50) (2022)
Ashley J Winter, Matthew T Rowe, Angus N M Weir, Nahida Akter, Sbusisiwe Z Mbatha, Paul D Walker, Christopher Williams, Zhongshu Song, Paul R Race, Christine L Willis, Matthew P Crump
Programmed Iteration Controls the Assembly of the Nonanoic Acid Side Chain of the Antibiotic Mupirocin. Angewandte Chemie (Weinheim an der Bergstrasse, Germany) 134 (50) (2022)
Ashley J Winter, Matthew T Rowe, Angus N M Weir, Nahida Akter, Sbusisiwe Z Mbatha, Paul D Walker, Christopher Williams, Zhongshu Song, Paul R Race, Christine L Willis, Matthew P Crump
Programmed Iteration Controls the Assembly of the Nonanoic Acid Side Chain of the Antibiotic Mupirocin. Angewandte Chemie (Weinheim an der Bergstrasse, Germany) 134 (50) (2022)
Andrew J Devine, Alice E Parnell, Catherine R Back, Nicholas R Lees, Samuel T Johns, Ainul Z Zulkepli, Rob Barringer, Katja Zorn, James E M Stach, Matthew P Crump, Martin A Hayes, Marc W Van der Kamp, Paul R Race, Christine L Willis
The Role of Cytochrome P450 AbyV in the Final Stages of Abyssomicin C Biosynthesis. Angewandte Chemie (Weinheim an der Bergstrasse, Germany) 135 (3) (2022)
James I Bowen, Luoyi Wang, Matthew P Crump, Christine L Willis
Ambruticins: tetrahydropyran ring formation and total synthesis. Organic & biomolecular chemistry 19 (28) (2022)
Paul D Walker, Angus N M Weir, Christine L Willis, Matthew P Crump
Polyketide β-branching: diversity, mechanism and selectivity. Natural product reports 38 (4) (2021)
Lisa-Maria Rečnik, Robert J Thatcher, Shahida Mallah, Craig P Butts, Graham L Collingridge, Elek Molnár, David E Jane, Christine L Willis
Synthesis and pharmacological characterisation of arctigenin analogues as antagonists of AMPA and kainate receptors. Organic & biomolecular chemistry 19 (42) (2021)
Katherine Williams, Claudio Greco, Andrew M Bailey, Christine L Willis
Core Steps to the Azaphilone Family of Fungal Natural Products. Chembiochem : a European journal of chemical biology 22 (21) (2021)
Paul D Walker, Matthew T Rowe, Ashley J Winter, Angus N M Weir, Nahida Akter, Luoyi Wang, Paul R Race, Christopher Williams, Zhongshu Song, Thomas J Simpson, Christine L Willis, Matthew P Crump
A Priming Cassette Generates Hydroxylated Acyl Starter Units in Mupirocin and Thiomarinol Biosynthesis. ACS chemical biology 15 (2) (2020)
Luoyi Wang, Zhongshu Song, Paul R Race, James Spencer, Thomas J Simpson, Matthew P Crump, Christine L Willis
Mixing and matching genes of marine and terrestrial origin in the biosynthesis of the mupirocin antibiotics. Chemical science 11 (20) (2020)
Jonathan A Davies, Freya M Bull, Paul D Walker, Angus N M Weir, Rob Lavigne, Joleen Masschelein, Thomas J Simpson, Paul R Race, Matthew P Crump, Christine L Willis
Total Synthesis of Kalimantacin A. Organic letters 22 (16) (2020)
Edith Rodriguez Venegas, Christine L Willis
A Bioinspired Strategy for the Enantioselective Synthesis of Bicyclic Oxygen Heterocycles. Organic letters 22 (7) (2020)
Christopher D Fage, Thomas Lathouwers, Michiel Vanmeert, Ling-Jie Gao, Kristof Vrancken, Eveline-Marie Lammens, Angus N M Weir, Ruben Degroote, Harry Cuppens, Simone Kosol, Thomas J Simpson, Matthew P Crump, Christine L Willis, Piet Herdewijn, Eveline Lescrinier, Rob Lavigne, Jozef Anné, Joleen Masschelein
The Kalimantacin Polyketide Antibiotics Inhibit Fatty Acid Biosynthesis in Staphylococcus aureus by Targeting the Enoyl-Acyl Carrier Protein Binding Site of FabI. Angewandte Chemie (International ed. in English) 59 (26) (2020)
Charles E Evans, James S Miners, Giulia Piva, Christine L Willis, David M Heard, Emma J Kidd, Mark A Good, Patrick Gavin Kehoe
ACE2 activation protects against cognitive decline and reduces amyloid pathology in the Tg2576 mouse model of Alzheimer's disease. Acta neuropathologica 139 (3) (2020)
Sam E Williams, Henry L Stennett, Catherine R Back, Kavita Tiwari, Jorge Ojeda Gomez, Martin R Challand, Katharine R Hendry, James Spencer, Angela E Essex-Lopresti, Christine L Willis, Paul Curnow, Paul R Race
The Bristol Sponge Microbiome Collection: A Unique Repository of Deep-Sea Microorganisms and Associated Natural Products. Antibiotics (Basel, Switzerland) 9 (8) (2020)
Kate M J de Mattos-Shipley, Catherine E Spencer, Claudio Greco, David M Heard, Daniel E O'Flynn, Trong T Dao, Zhongshu Song, Nicholas P Mulholland, Jason L Vincent, Thomas J Simpson, Russell J Cox, Andrew M Bailey, Christine L Willis
Uncovering biosynthetic relationships between antifungal nonadrides and octadrides. Chemical science 11 (42) (2020)
Jack A Connolly, Amber Wilson, Malgorzata Macioszek, Zhongshu Song, Luoyi Wang, Hadi H Mohammad, Mukul Yadav, Maura di Martino, Claire E Miller, Joanne Hothersall, Anthony S Haines, Elton R Stephens, Matthew P Crump, Christine L Willis, Thomas J Simpson, Peter J Winn, Christopher M Thomas
Defining the genes for the final steps in biosynthesis of the complex polyketide antibiotic mupirocin by Pseudomonas fluorescens NCIMB10586. Scientific reports 9 (1) (2019)
Paul D Walker, Christopher Williams, Angus N M Weir, Luoyi Wang, John Crosby, Paul R Race, Thomas J Simpson, Christine L Willis, Matthew P Crump
Control of β-Branching in Kalimantacin Biosynthesis: Application of 13 C NMR to Polyketide Programming. Angewandte Chemie (International ed. in English) 58 (36) (2019)
Claudio Greco, Kate de Mattos-Shipley, Andrew M Bailey, Nicholas P Mulholland, Jason L Vincent, Christine L Willis, Russell J Cox, Thomas J Simpson
Structure revision of cryptosporioptides and determination of the genetic basis for dimeric xanthone biosynthesis in fungi. Chemical science 10 (10) (2019)
Kate M J de Mattos-Shipley, Claudio Greco, David M Heard, Gemma Hough, Nicholas P Mulholland, Jason L Vincent, Jason Micklefield, Thomas J Simpson, Christine L Willis, Russell J Cox, Andrew M Bailey
The cycloaspeptides: uncovering a new model for methylated nonribosomal peptide biosynthesis. Chemical science 9 (17) (2018)
Hadi H Mohammad, Jack A Connolly, Zhongshu Song, Joanne Hothersall, Paul R Race, Christine L Willis, Christopher M Thomas, Peter J Winn, Christopher M Thomas
Fine Tuning of Antibiotic Activity by a Tailoring Hydroxylase in a Trans-AT Polyketide Synthase Pathway. Chembiochem : a European journal of chemical biology 19 (8) (2018)
Risa Nofiani, Kate de Mattos-Shipley, Karen E Lebe, Li-Chen Han, Zafar Iqbal, Andrew M Bailey, Christine L Willis, Thomas J Simpson, Russell J Cox
Strobilurin biosynthesis in Basidiomycete fungi. Nature communications 9 (1) (2018)
Agnieszka J Szwalbe, Katherine Williams, Zhongshu Song, Kate de Mattos-Shipley, Jason L Vincent, Andrew M Bailey, Christine L Willis, Russell J Cox, Thomas J Simpson
Characterisation of the biosynthetic pathway to agnestins A and B reveals the reductive route to chrysophanol in fungi. Chemical science 10 (1) (2018)
Iain R G Thistlethwaite, Freya M Bull, Chengsen Cui, Paul D Walker, Shu-Shan Gao, Luoyi Wang, Zhongshu Song, Joleen Masschelein, Rob Lavigne, Matthew P Crump, Paul R Race, Thomas J Simpson, Christine L Willis
Elucidation of the relative and absolute stereochemistry of the kalimantacin/batumin antibiotics. Chemical science 8 (9) (2017)
Shu-Shan Gao, Luoyi Wang, Zhongshu Song, Joanne Hothersall, Elton R Stevens, Jack Connolly, Peter J Winn, Russell J Cox, Matthew P Crump, Paul R Race, Christopher M Thomas, Thomas J Simpson, Christine L Willis
Selected Mutations Reveal New Intermediates in the Biosynthesis of Mupirocin and the Thiomarinol Antibiotics. Angewandte Chemie (International ed. in English) 56 (14) (2017)

Christine L Willis.css-eqlu8i{font-size:small;padding-left:4px;} (C L Willis)

Publication Activity (10 Years)

Top Topics

Top Venues

Christine L Willis (C L Willis)