Thomas Langer

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 44

Top Venues

The Journal of cell biology

Nature cell biology

The EMBO journal

Science advances

Max Planck Institute for Biology of Ageing

Ludwig-Maximilians-University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Max Planck Institute for Biology of Ageing Aug 01 2018

Germany

Director :: Mitochondrial Proteostasis in Ageing

Institute for Genetics, University of Cologne - Jul 31 2018

Germany

Professor (C4/W3)

Education History

Ludwig-Maximilians-University

Germany

PHD :: Laboratory of Dr. Franz-Ulrich Hartl

Publications

Sinika Henschke, Hendrik Nolte, Judith Magoley, Tatjana Kleele, Claus Brandt, A Christine Hausen, Claudia M Wunderlich, Corinna A Bauder, Philipp Aschauer, Suliana Manley, Thomas Langer, Frank Thomas Wunderlich, Jens C Brüning
Food perception promotes phosphorylation of MFFS131 and mitochondrial fragmentation in liver. Science (New York, N.Y.) 384 (6694) (2024)
Marta Zaninello, Tim Schlegel, Hendrik Nolte, Mujeeb Pirzada, Elisa Savino, Esther Barth, Ines Klein, Hauke Wüstenberg, Tesmin Uddin, Lisa Wolff, Brunhilde Wirth, Helmar C Lehmann, Jean-Michel Cioni, Thomas Langer, Elena I Rugarli
CLUH maintains functional mitochondria and translation in motoneuronal axons and prevents peripheral neuropathy. Science advances 10 (22) (2024)
Megan J Baker, Kai Uwe Blau, Alexander J Anderson, Catherine S Palmer, Laura F Fielden, Jordan James Crameri, Dusanka Milenkovic, David R Thorburn, Ann E Frazier, Thomas Langer, Diana Stojanovski
CLPB disaggregase dysfunction impacts the functional integrity of the proteolytic SPY complex. The Journal of cell biology 223 (3) (2024)
Sinika Henschke, Hendrik Nolte, Judith Magoley, Tatjana Kleele, Claus Brandt, A Christine Hausen, Claudia M Wunderlich, Corinna A Bauder, Philipp Aschauer, Suliana Manley, Thomas Langer, Frank Thomas Wunderlich, Jens C Brüning
Food perception promotes phosphorylation of MFFS131 and mitochondrial fragmentation in liver. Science (New York, N.Y.) 384 (6694) (2024)
Megan J Baker, Kai Uwe Blau, Alexander J Anderson, Catherine S Palmer, Laura F Fielden, Jordan James Crameri, Dusanka Milenkovic, David R Thorburn, Ann E Frazier, Thomas Langer, Diana Stojanovski
CLPB disaggregase dysfunction impacts the functional integrity of the proteolytic SPY complex. The Journal of cell biology 223 (3) (2024)
Megan J Baker, Kai Uwe Blau, Alexander J Anderson, Catherine S Palmer, Laura F Fielden, Jordan James Crameri, Dusanka Milenkovic, David R Thorburn, Ann E Frazier, Thomas Langer, Diana Stojanovski
CLPB disaggregase dysfunction impacts the functional integrity of the proteolytic SPY complex. The Journal of cell biology 223 (3) (2024)
Henry Sawczyc, Takashi Tatsuta, Carl Öster, Spyridon Kosteletos, Sascha Lange, Claudia Bohg, Thomas Langer, Sascha Lange
Lipid-polymer nanoparticles to probe the native-like environment of intramembrane rhomboid protease GlpG and its activity. Nature communications 15 (1) (2024)
Megan J Baker, Kai Uwe Blau, Alexander J Anderson, Catherine S Palmer, Laura F Fielden, Jordan James Crameri, Dusanka Milenkovic, David R Thorburn, Ann E Frazier, Thomas Langer, Diana Stojanovski
CLPB disaggregase dysfunction impacts the functional integrity of the proteolytic SPY complex. The Journal of cell biology 223 (3) (2024)
Marta Zaninello, Tim Schlegel, Hendrik Nolte, Mujeeb Pirzada, Elisa Savino, Esther Barth, Ines Klein, Hauke Wüstenberg, Tesmin Uddin, Lisa Wolff, Brunhilde Wirth, Helmar C Lehmann, Jean-Michel Cioni, Thomas Langer, Elena I Rugarli
CLUH maintains functional mitochondria and translation in motoneuronal axons and prevents peripheral neuropathy. Science advances 10 (22) (2024)
Megan J Baker, Kai Uwe Blau, Alexander J Anderson, Catherine S Palmer, Laura F Fielden, Jordan James Crameri, Dusanka Milenkovic, David R Thorburn, Ann E Frazier, Thomas Langer, Diana Stojanovski
CLPB disaggregase dysfunction impacts the functional integrity of the proteolytic SPY complex. The Journal of cell biology 223 (3) (2024)
Marta Zaninello, Tim Schlegel, Hendrik Nolte, Mujeeb Pirzada, Elisa Savino, Esther Barth, Ines Klein, Hauke Wüstenberg, Tesmin Uddin, Lisa Wolff, Brunhilde Wirth, Helmar C Lehmann, Jean-Michel Cioni, Thomas Langer, Elena I Rugarli
CLUH maintains functional mitochondria and translation in motoneuronal axons and prevents peripheral neuropathy. Science advances 10 (22) (2024)
Sofia Ahola, Lilli A Pazurek, Fiona Mayer, Philipp Lampe, Steffen Hermans, Lore Becker, Oana V Amarie, Helmut Fuchs, Valerie Gailus-Durner, Martin Hrabě de Angelis, Dietmar Riedel, Hendrik Nolte, Thomas Langer
Opa1 processing is dispensable in mouse development but is protective in mitochondrial cardiomyopathy. Science advances 10 (31) (2024)
Megan J Baker, Kai Uwe Blau, Alexander J Anderson, Catherine S Palmer, Laura F Fielden, Jordan James Crameri, Dusanka Milenkovic, David R Thorburn, Ann E Frazier, Thomas Langer, Diana Stojanovski
CLPB disaggregase dysfunction impacts the functional integrity of the proteolytic SPY complex. The Journal of cell biology 223 (3) (2024)
Sofia Ahola, Lilli A Pazurek, Fiona Mayer, Philipp Lampe, Steffen Hermans, Lore Becker, Oana V Amarie, Helmut Fuchs, Valerie Gailus-Durner, Martin Hrabě de Angelis, Dietmar Riedel, Hendrik Nolte, Thomas Langer
Opa1 processing is dispensable in mouse development but is protective in mitochondrial cardiomyopathy. Science advances 10 (31) (2024)
Megan J Baker, Kai Uwe Blau, Alexander J Anderson, Catherine S Palmer, Laura F Fielden, Jordan James Crameri, Dusanka Milenkovic, David R Thorburn, Ann E Frazier, Thomas Langer, Diana Stojanovski
CLPB disaggregase dysfunction impacts the functional integrity of the proteolytic SPY complex. The Journal of cell biology 223 (3) (2024)
Esra Peker, Konstantin Weiss, Jiyao Song, Christine Zarges, Sarah Gerlich, Volker Boehm, Aleksandra Trifunovic, Thomas Langer, Niels H Gehring, Thomas Becker, Jan Riemer
A two-step mitochondrial import pathway couples the disulfide relay with matrix complex I biogenesis. The Journal of cell biology 222 (7) (2023)
Soni Deshwal, Mashun Onishi, Takashi Tatsuta, Tim Bartsch, Eileen Cors, Katharina Ried, Kathrin Lemke, Hendrik Nolte, Patrick Giavalisco, Thomas Langer
Mitochondria regulate intracellular coenzyme Q transport and ferroptotic resistance via STARD7. Nature cell biology 25 (2) (2023)
Esra Peker, Konstantin Weiss, Jiyao Song, Christine Zarges, Sarah Gerlich, Volker Boehm, Aleksandra Trifunovic, Thomas Langer, Niels H Gehring, Thomas Becker, Jan Riemer
A two-step mitochondrial import pathway couples the disulfide relay with matrix complex I biogenesis. The Journal of cell biology 222 (7) (2023)
Soni Deshwal, Mashun Onishi, Takashi Tatsuta, Tim Bartsch, Eileen Cors, Katharina Ried, Kathrin Lemke, Hendrik Nolte, Patrick Giavalisco, Thomas Langer
Mitochondria regulate intracellular coenzyme Q transport and ferroptotic resistance via STARD7. Nature cell biology 25 (2) (2023)
Elias Adriaenssens, Bob Asselbergh, Pablo Rivera-Mejías, Sven Bervoets, Leen Vendredy, Vicky De Winter, Katrien Spaas, Riet de Rycke, Gert van Isterdael, Francis Impens, Thomas Langer, Vincent Timmerman
Small heat shock proteins operate as molecular chaperones in the mitochondrial intermembrane space. Nature cell biology (2023)
Elias Adriaenssens, Bob Asselbergh, Pablo Rivera-Mejías, Sven Bervoets, Leen Vendredy, Vicky De Winter, Katrien Spaas, Riet de Rycke, Gert van Isterdael, Francis Impens, Thomas Langer, Vincent Timmerman
Small heat shock proteins operate as molecular chaperones in the mitochondrial intermembrane space. Nature cell biology 25 (3) (2023)
Esra Peker, Konstantin Weiss, Jiyao Song, Christine Zarges, Sarah Gerlich, Volker Boehm, Aleksandra Trifunovic, Thomas Langer, Niels H Gehring, Thomas Becker, Jan Riemer
A two-step mitochondrial import pathway couples the disulfide relay with matrix complex I biogenesis. The Journal of cell biology 222 (7) (2023)
Elias Adriaenssens, Bob Asselbergh, Pablo Rivera-Mejías, Sven Bervoets, Leen Vendredy, Vicky De Winter, Katrien Spaas, Riet de Rycke, Gert van Isterdael, Francis Impens, Thomas Langer, Vincent Timmerman
Small heat shock proteins operate as molecular chaperones in the mitochondrial intermembrane space. Nature cell biology 25 (3) (2023)
Esra Peker, Konstantin Weiss, Jiyao Song, Christine Zarges, Sarah Gerlich, Volker Boehm, Aleksandra Trifunovic, Thomas Langer, Niels H Gehring, Thomas Becker, Jan Riemer
A two-step mitochondrial import pathway couples the disulfide relay with matrix complex I biogenesis. The Journal of cell biology 222 (7) (2023)
Jun Yong Kim, Ilian Atanassov, Frederik Dethloff, Lara Kroczek, Thomas Langer
Time-resolved proteomic analyses of senescence highlight metabolic rewiring of mitochondria. Life science alliance 6 (9) (2023)
Soni Deshwal, Mashun Onishi, Takashi Tatsuta, Tim Bartsch, Eileen Cors, Katharina Ried, Kathrin Lemke, Hendrik Nolte, Patrick Giavalisco, Thomas Langer
Mitochondria regulate intracellular coenzyme Q transport and ferroptotic resistance via STARD7. Nature cell biology (2023)
Soni Deshwal, Mashun Onishi, Takashi Tatsuta, Tim Bartsch, Eileen Cors, Katharina Ried, Kathrin Lemke, Hendrik Nolte, Patrick Giavalisco, Thomas Langer
Mitochondria regulate intracellular coenzyme Q transport and ferroptotic resistance via STARD7. Nature cell biology 25 (2) (2023)
Soni Deshwal, Mashun Onishi, Takashi Tatsuta, Tim Bartsch, Eileen Cors, Katharina Ried, Kathrin Lemke, Hendrik Nolte, Patrick Giavalisco, Thomas Langer
Mitochondria regulate intracellular coenzyme Q transport and ferroptotic resistance via STARD7. Nature cell biology 25 (2) (2023)
Nils Grotehans, Lynn McGarry, Hendrik Nolte, Vanessa Xavier, Moritz Kroker, Álvaro Jesús Narbona-Pérez, Soni Deshwal, Patrick Giavalisco, Thomas Langer, Thomas MacVicar
Ribonucleotide synthesis by NME6 fuels mitochondrial gene expression. The EMBO journal (2023)
Soni Deshwal, Mashun Onishi, Takashi Tatsuta, Tim Bartsch, Eileen Cors, Katharina Ried, Kathrin Lemke, Hendrik Nolte, Patrick Giavalisco, Thomas Langer
Mitochondria regulate intracellular coenzyme Q transport and ferroptotic resistance via STARD7. Nature cell biology 25 (2) (2023)
Maria Patron, Daryna Tarasenko, Hendrik Nolte, Lara Kroczek, Mausumi Ghosh, Yohsuke Ohba, Yvonne Lasarzewski, Zeinab Alsadat Ahmadi, Alfredo Cabrera-Orefice, Akinori Eyiama, Tim Kellermann, Elena I Rugarli, Ulrich Brandt, Michael Meinecke, Thomas Langer
Regulation of mitochondrial proteostasis by the proton gradient. The EMBO journal 41 (16) (2022)
Yohsuke Ohba, Thomas MacVicar, Thomas Langer
Regulation of mitochondrial plasticity by the i-AAA protease YME1L. Biological chemistry 401 (6-7) (2021)
Hans-Georg Sprenger, Thomas MacVicar, Amir Bahat, Kai Uwe Fiedler, Steffen Hermans, Denise Ehrentraut, Katharina Ried, Dusanka Milenkovic, Nina A Bonekamp, Nils-Göran Larsson, Hendrik Nolte, Patrick Giavalisco, Thomas Langer
Cellular pyrimidine imbalance triggers mitochondrial DNA-dependent innate immunity. Nature metabolism 3 (5) (2021)
Tim König, Hendrik Nolte, Mari J Aaltonen, Takashi Tatsuta, Michiel Krols, Thomas Stroh, Thomas Langer, Heidi M McBride
MIROs and DRP1 drive mitochondrial-derived vesicle biogenesis and promote quality control. Nature cell biology (2021)
Emma Cretin, Priscilla Lopes, Elodie Vimont, Takashi Tatsuta, Thomas Langer, Anastasia D Gazi, Martin Sachse, Patrick Yu-Wai-Man, Pascal Reynier, Timothy Wai
High-throughput screening identifies suppressors of mitochondrial fragmentation in OPA1 fibroblasts. EMBO molecular medicine 13 (6) (2021)
Roland Lill, Thomas Langer, Johannes M Herrmann
Walter Neupert (1939-2019), a pioneer of mitochondrial biogenesis and morphology. The EMBO journal 38 (17) (2019)
Xeni Miliara, Takashi Tatsuta, Jamie-Lee Berry, Sarah L Rouse, Kübra Solak, Dror S Chorev, Di Wu, Carol V Robinson, Stephen J Matthews, Thomas Langer
Structural determinants of lipid specificity within Ups/PRELI lipid transfer proteins. Nature communications 10 (1) (2019)
Hans-Georg Sprenger, Gulzar Wani, Annika Hesseling, Tim König, Maria Patron, Thomas MacVicar, Sofia Ahola, Timothy Wai, Esther Barth, Elena I Rugarli, Matteo Bergami, Thomas Langer
Loss of the mitochondrial i-AAA protease YME1L leads to ocular dysfunction and spinal axonopathy. EMBO molecular medicine 11 (1) (2019)
Talha Rashid, Ivan Nemazanyy, Cecilia Paolini, Takashi Tatsuta, Paul Crespin, Delphine de Villeneuve, Susanne Brodesser, Paule Benit, Pierre Rustin, Martin A Baraibar, Onnik Agbulut, Anne Olivier, Feliciano Protasi, Thomas Langer, Roman Chrast, Pascale de Lonlay, Helene de Foucauld, Bert Blaauw, Mario Pende
Lipin1 deficiency causes sarcoplasmic reticulum stress and chaperone-responsive myopathy. The EMBO journal 38 (1) (2018)
Shotaro Saita, Takashi Tatsuta, Philipp A Lampe, Tim König, Yohsuke Ohba, Thomas Langer
PARL partitions the lipid transfer protein STARD7 between the cytosol and mitochondria. The EMBO journal 37 (4) (2018)
Frank Richter, Sven Dennerlein, Miroslav Nikolov, Daniel C Jans, Nataliia Naumenko, Abhishek Aich, Thomas MacVicar, Andreas Linden, Stefan Jakobs, Henning Urlaub, Thomas Langer, Peter Rehling
ROMO1 is a constituent of the human presequence translocase required for YME1L protease import. The Journal of cell biology 218 (2) (2018)
Shotaro Saita, Hendrik Nolte, Kai Uwe Fiedler, Hamid Kashkar, A Saskia Venne, René P Zahedi, Marcus Krüger, Thomas Langer
PARL mediates Smac proteolytic maturation in mitochondria to promote apoptosis. Nature cell biology 19 (4) (2017)
Thomas MacVicar, Thomas Langer
OPA1 processing in cell death and disease - the long and short of it. Journal of cell science 129 (12) (2016)
Timothy Wai, Shotaro Saita, Hendrik Nolte, Sebastian Müller, Tim König, Ricarda Richter-Dennerlein, Hans-Georg Sprenger, Joaquin Madrenas, Mareike Mühlmeister, Ulrich Brandt, Marcus Krüger, Thomas Langer
The membrane scaffold SLP2 anchors a proteolytic hub in mitochondria containing PARL and the i-AAA protease YME1L. EMBO reports 17 (12) (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Thomas Langer