Nils-Göran Larsson (N-G Larsson)

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 35

Top Topics

Duchenne Muscular Dystrophy

Mitochondrial Dna

Immune Response

Top Venues

Nature metabolism

Science advances

NPJ Parkinson's disease

This page only lists publications with an associated author ORCID identifier.

Publications

Shan Jiang, Taolin Yuan, Florian A Schober, Arnaud Mourier, Nathalia R V Dragano, Laura S Kremer, Diana Rubalcava-Gracia, Fynn M Hansen, Melissa Borg, Mara Mennuni, Roberta Filograna, David Alsina, Jelena Misic, Camilla Koolmeister, Polyxeni Papadea, Martin Hrabe de Angelis, Lipeng Ren, Olov Andersson, Anke Unger, Tim Bergbrede, Raffaella Di Lucrezia, Rolf Wibom, Juleen R Zierath, Anna Krook, Patrick Giavalisco, Matthias Mann, Nils-Göran Larsson
Inhibition of mammalian mtDNA transcription acts paradoxically to reverse diet-induced hepatosteatosis and obesity. Nature metabolism (2024)
Shan Jiang, Taolin Yuan, Florian A Schober, Arnaud Mourier, Nathalia R V Dragano, Laura S Kremer, Diana Rubalcava-Gracia, Fynn M Hansen, Melissa Borg, Mara Mennuni, Roberta Filograna, David Alsina, Jelena Misic, Camilla Koolmeister, Polyxeni Papadea, Martin Hrabe de Angelis, Lipeng Ren, Olov Andersson, Anke Unger, Tim Bergbrede, Raffaella Di Lucrezia, Rolf Wibom, Juleen R Zierath, Anna Krook, Patrick Giavalisco, Matthias Mann, Nils-Göran Larsson
Inhibition of mammalian mtDNA transcription acts paradoxically to reverse diet-induced hepatosteatosis and obesity. Nature metabolism 6 (6) (2024)
Roberta Filograna, Jule Gerlach, Hae-Na Choi, Giovanni Rigoni, Michela Barbaro, Mikael Oscarson, Seungmin Lee, Katarina Tiklova, Markus Ringnér, Camilla Koolmeister, Rolf Wibom, Sara Riggare, Inger Nennesmo, Thomas Perlmann, Anna Wredenberg, Anna Wedell, Elisa Motori, Per Svenningsson, Nils-Göran Larsson
PARKIN is not required to sustain OXPHOS function in adult mammalian tissues. NPJ Parkinson's disease 10 (1) (2024)
Diana Rubalcava-Gracia, Kristina Bubb, Fredrik Levander, Stephen P Burr, Amelie V August, Patrick F Chinnery, Camilla Koolmeister, Nils-Göran Larsson
LRPPRC and SLIRP synergize to maintain sufficient and orderly mammalian mitochondrial translation. Nucleic acids research (2024)
Polyxeni Papadea, Nils-Göran Larsson
Older age reduces mtDNA mutation inheritance. Nature aging (2024)
Roberta Filograna, Jule Gerlach, Hae-Na Choi, Giovanni Rigoni, Michela Barbaro, Mikael Oscarson, Seungmin Lee, Katarina Tiklova, Markus Ringnér, Camilla Koolmeister, Rolf Wibom, Sara Riggare, Inger Nennesmo, Thomas Perlmann, Anna Wredenberg, Anna Wedell, Elisa Motori, Per Svenningsson, Nils-Göran Larsson
PARKIN is not required to sustain OXPHOS function in adult mammalian tissues. NPJ Parkinson's disease 10 (1) (2024)
Shan Jiang, Taolin Yuan, Florian A Schober, Arnaud Mourier, Nathalia R V Dragano, Laura S Kremer, Diana Rubalcava-Gracia, Fynn M Hansen, Melissa Borg, Mara Mennuni, Roberta Filograna, David Alsina, Jelena Misic, Camilla Koolmeister, Polyxeni Papadea, Martin Hrabe de Angelis, Lipeng Ren, Olov Andersson, Anke Unger, Tim Bergbrede, Raffaella Di Lucrezia, Rolf Wibom, Juleen R Zierath, Anna Krook, Patrick Giavalisco, Matthias Mann, Nils-Göran Larsson
Inhibition of mammalian mtDNA transcription acts paradoxically to reverse diet-induced hepatosteatosis and obesity. Nature metabolism 6 (6) (2024)
Shan Jiang, Taolin Yuan, Florian A Schober, Arnaud Mourier, Nathalia R V Dragano, Laura S Kremer, Diana Rubalcava-Gracia, Fynn M Hansen, Melissa Borg, Mara Mennuni, Roberta Filograna, David Alsina, Jelena Misic, Camilla Koolmeister, Polyxeni Papadea, Martin Hrabe de Angelis, Lipeng Ren, Olov Andersson, Anke Unger, Tim Bergbrede, Raffaella Di Lucrezia, Rolf Wibom, Juleen R Zierath, Anna Krook, Patrick Giavalisco, Matthias Mann, Nils-Göran Larsson
Inhibition of mammalian mtDNA transcription acts paradoxically to reverse diet-induced hepatosteatosis and obesity. Nature metabolism 6 (6) (2024)
Laura S Kremer, Lyuba V Bozhilova, Diana Rubalcava-Gracia, Roberta Filograna, Mamta Upadhyay, Camilla Koolmeister, Patrick F Chinnery, Nils-Göran Larsson
A role for BCL2L13 and autophagy in germline purifying selection of mtDNA. PLoS genetics 19 (1) (2023)
Laura S Kremer, Lyuba V Bozhilova, Diana Rubalcava-Gracia, Roberta Filograna, Mamta Upadhyay, Camilla Koolmeister, Patrick F Chinnery, Nils-Göran Larsson
A role for BCL2L13 and autophagy in germline purifying selection of mtDNA. PLoS genetics 19 (1) (2023)
Laura S Kremer, Lyuba V Bozhilova, Diana Rubalcava-Gracia, Roberta Filograna, Mamta Upadhyay, Camilla Koolmeister, Patrick F Chinnery, Nils-Göran Larsson
A role for BCL2L13 and autophagy in germline purifying selection of mtDNA. PLoS genetics 19 (1) (2023)
Laura S Kremer, Lyuba V Bozhilova, Diana Rubalcava-Gracia, Roberta Filograna, Mamta Upadhyay, Camilla Koolmeister, Patrick F Chinnery, Nils-Göran Larsson
A role for BCL2L13 and autophagy in germline purifying selection of mtDNA. PLoS genetics 19 (1) (2023)
Laura S Kremer, Lyuba V Bozhilova, Diana Rubalcava-Gracia, Roberta Filograna, Mamta Upadhyay, Camilla Koolmeister, Patrick F Chinnery, Nils-Göran Larsson
A role for BCL2L13 and autophagy in germline purifying selection of mtDNA. PLoS genetics 19 (1) (2023)
Fynn M Hansen, Laura S Kremer, Ozge Karayel, Isabell Bludau, Nils-Göran Larsson, Inge Kühl, Matthias Mann
Mitochondrial phosphoproteomes are functionally specialized across tissues. Life science alliance 7 (2) (2023)
Laura S Kremer, Lyuba V Bozhilova, Diana Rubalcava-Gracia, Roberta Filograna, Mamta Upadhyay, Camilla Koolmeister, Patrick F Chinnery, Nils-Göran Larsson
A role for BCL2L13 and autophagy in germline purifying selection of mtDNA. PLoS genetics 19 (1) (2023)
Laura S Kremer, Lyuba V Bozhilova, Diana Rubalcava-Gracia, Roberta Filograna, Mamta Upadhyay, Camilla Koolmeister, Patrick F Chinnery, Nils-Göran Larsson
A role for BCL2L13 and autophagy in germline purifying selection of mtDNA. PLoS genetics 19 (1) (2023)
Laura S Kremer, Lyuba V Bozhilova, Diana Rubalcava-Gracia, Roberta Filograna, Mamta Upadhyay, Camilla Koolmeister, Patrick F Chinnery, Nils-Göran Larsson
A role for BCL2L13 and autophagy in germline purifying selection of mtDNA. PLoS genetics 19 (1) (2023)
Jelena Misic, Dusanka Milenkovic, Ali Al-Behadili, Xie Xie, Min Jiang, Shan Jiang, Roberta Filograna, Camilla Koolmeister, Stefan J Siira, Louise Jenninger, Aleksandra Filipovska, Anders R Clausen, Leonardo Caporali, Maria Lucia Valentino, Chiara La Morgia, Valerio Carelli, Thomas J Nicholls, Anna Wredenberg, Maria Falkenberg, Nils-Göran Larsson
Mammalian RNase H1 directs RNA primer formation for mtDNA replication initiation and is also necessary for mtDNA replication completion. Nucleic acids research 50 (15) (2022)
Dusanka Milenkovic, Adrián Sanz-Moreno, Julia Calzada-Wack, Birgit Rathkolb, Oana Veronica Amarie, Raffaele Gerlini, Antonio Aguilar-Pimentel, Jelena Misic, Marie-Lune Simard, Eckhard Wolf, Helmut Fuchs, Valerie Gailus-Durner, Martin Hrabě de Angelis, Nils-Göran Larsson
Mice lacking the mitochondrial exonuclease MGME1 develop inflammatory kidney disease with glomerular dysfunction. PLoS genetics 18 (5) (2022)
Mara Mennuni, Roberta Filograna, Andrea Felser, Nina A Bonekamp, Patrick Giavalisco, Oleksandr Lytovchenko, Nils-Göran Larsson
Metabolic resistance to the inhibition of mitochondrial transcription revealed by CRISPR-Cas9 screen. EMBO reports (2021)
Hans-Georg Sprenger, Thomas MacVicar, Amir Bahat, Kai Uwe Fiedler, Steffen Hermans, Denise Ehrentraut, Katharina Ried, Dusanka Milenkovic, Nina A Bonekamp, Nils-Göran Larsson, Hendrik Nolte, Patrick Giavalisco, Thomas Langer
Cellular pyrimidine imbalance triggers mitochondrial DNA-dependent innate immunity. Nature metabolism 3 (5) (2021)
Min Jiang, Xie Xie, Xuefeng Zhu, Shan Jiang, Dusanka Milenkovic, Jelena Misic, Yonghong Shi, Nirwan Tandukar, Xinping Li, Ilian Atanassov, Louise Jenninger, Emily Hoberg, Sara Albarran-Gutierrez, Zsolt Szilagyi, Bertil Macao, Stefan J Siira, Valerio Carelli, Jack D Griffith, Claes M Gustafsson, Thomas J Nicholls, Aleksandra Filipovska, Nils-Göran Larsson, Maria Falkenberg
The mitochondrial single-stranded DNA binding protein is essential for initiation of mtDNA replication. Science advances 7 (27) (2021)
Roberta Filograna, Seungmin Lee, Katarína Tiklová, Mara Mennuni, Viktor Tasselius, Markus Ringnér, Linda Gillberg, Elena Sopova, Oleg Shupliakov, Camilla Koolmeister, Lars Olson, Thomas Perlmann, Nils-Göran Larsson
Mitochondrial dysfunction in adult midbrain dopamine neurons triggers an early immune response. PLoS genetics 17 (9) (2021)
Nina A Bonekamp, Min Jiang, Elisa Motori, Rodolfo Garcia Villegas, Camilla Koolmeister, Ilian Atanassov, Andrea Mesaros, Chan Bae Park, Nils-Göran Larsson
High levels of TFAM repress mammalian mitochondrial DNA transcription in vivo. Life science alliance 4 (11) (2021)
Elisa Motori, Ilian Atanassov, S M V Kochan, K Folz-Donahue, V Sakthivelu, Patrick Giavalisco, N Toni, Julien Puyal, Nils-Göran Larsson
Neuronal metabolic rewiring promotes resilience to neurodegeneration caused by mitochondrial dysfunction. Science advances 6 (35) (2020)
Roberta Filograna, Mara Mennuni, David Alsina, Nils-Göran Larsson
Mitochondrial DNA copy number in human disease: the more the better? FEBS letters 595 (8) (2020)
Swaraj Basu, Xie Xie, Jay P Uhler, Carola Hedberg-Oldfors, Dusanka Milenkovic, Olivier R Baris, Sammy Kimoloi, Stanka Matic, James Bruce Stewart, Nils-Göran Larsson, Rudolf J Wiesner, Anders Oldfors, Claes M Gustafsson, Maria Falkenberg, Erik Larsson Lekholm
Accurate mapping of mitochondrial DNA deletions and duplications using deep sequencing. PLoS genetics 16 (12) (2020)
David Alsina, Oleksandr Lytovchenko, Aleksandra Schab, Ilian Atanassov, Florian A Schober, Min Jiang, Camilla Koolmeister, Anna Wedell, Robert W Taylor, Anna Wredenberg, Nils-Göran Larsson
FBXL4 deficiency increases mitochondrial removal by autophagy. EMBO molecular medicine 12 (7) (2020)
Sushma Sharma, Camilla Koolmeister, Phong Tran, Anna Karin Nilsson, Nils-Göran Larsson, Andrei Chabes
Proofreading deficiency in mitochondrial DNA polymerase does not affect total dNTP pools in mouse embryos. Nature metabolism 2 (8) (2020)
Nina A Bonekamp, Bradley Peter, Hauke S Hillen, Andrea Felser, Tim Bergbrede, Axel Choidas, Moritz Horn, Anke Unger, Raffaella Di Lucrezia, Ilian Atanassov, Xinping Li, Uwe Koch, Sascha Menninger, Joanna Boros, Peter Habenberger, Patrick Giavalisco, Patrick Cramer, Martin S Denzel, Peter Nussbaumer, Bert Klebl, Maria Falkenberg, Claes M Gustafsson, Nils-Göran Larsson
Small-molecule inhibitors of human mitochondrial DNA transcription. Nature 588 (7839) (2020)
Eduardo Silva Ramos, Elisa Motori, Christian Brüser, Inge Kühl, Assa Yeroslaviz, Benedetta Ruzzenente, Johanna H K Kauppila, Jakob D Busch, Kjell Hultenby, Bianca Hermine Habermann, Stefan Jakobs, Nils-Göran Larsson, Arnaud Mourier
Mitochondrial fusion is required for regulation of mitochondrial DNA replication. PLoS genetics 15 (6) (2019)
Shan Jiang, Camilla Koolmeister, Jelena Misic, Stefan Siira, Inge Kühl, Eduardo Silva Ramos, Maria Miranda, Min Jiang, Viktor Posse, Oleksandr Lytovchenko, Ilian Atanassov, Florian A Schober, Rolf Wibom, Kjell Hultenby, Dusanka Milenkovic, Claes M Gustafsson, Aleksandra Filipovska, Nils-Göran Larsson
TEFM regulates both transcription elongation and RNA processing in mitochondria. EMBO reports 20 (6) (2019)
Sandra R Bacman, Johanna H K Kauppila, Claudia V Pereira, Nadee Nissanka, Maria Miranda, Milena Pinto, Sion L Williams, Nils-Göran Larsson, James Bruce Stewart, Carlos T Moraes
MitoTALEN reduces mutant mtDNA load and restores tRNAAla levels in a mouse model of heteroplasmic mtDNA mutation. Nature medicine 24 (11) (2018)
Stanka Matic, Min Jiang, Thomas J Nicholls, Jay P Uhler, Caren Dirksen-Schwanenland, Paola Loguercio Polosa, Marie-Lune Simard, Xinping Li, Ilian Atanassov, Oliver Rackham, Aleksandra Filipovska, James Bruce Stewart, Maria Falkenberg, Nils-Göran Larsson, Dusanka Milenkovic
Mice lacking the mitochondrial exonuclease MGME1 accumulate mtDNA deletions without developing progeria. Nature communications 9 (1) (2018)
Inge Kühl, Maria Miranda, Ilian Atanassov, Irina Kuznetsova, Yvonne Hinze, Arnaud Mourier, Aleksandra Filipovska, Nils-Göran Larsson
Transcriptomic and proteomic landscape of mitochondrial dysfunction reveals secondary coenzyme Q deficiency in mammals. eLife 6 (2017)