Thomas Reinheckel

ORCID

Publication Activity (10 Years)

Years Active: 2019-2023
Publications (10 Years): 13

Top Venues

Science signaling

Nature communications

Oncogene

Cellular and molecular life sciences : CMLS

University of Freiburg

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Freiburg Jan 01 2000

Germany

Professor :: Molecular Medicine

Publications

Emilia Neuwirt, Giovanni Magnani, Tamara Ćiković, Svenja Wöhrle, Larissa Fischer, Anna Kostina, Stephan Flemming, Nora J Fischenich, Benedikt S Saller, Oliver Gorka, Steffen Renner, Claudia Agarinis, Christian N Parker, Andreas Boettcher, Christopher J Farady, Rebecca Kesselring, Christopher Berlin, Rolf Backofen, Marta Rodriguez-Franco, Clemens Kreutz, Marco Prinz, Martina Tholen, Thomas Reinheckel, Thomas Ott, Christina J Groß, Philipp J Jost, Olaf Gross
Tyrosine kinase inhibitors can activate the NLRP3 inflammasome in myeloid cells through lysosomal damage and cell lysis. Science signaling 16 (768) (2023)
Emilia Neuwirt, Giovanni Magnani, Tamara Ćiković, Svenja Wöhrle, Larissa Fischer, Anna Kostina, Stephan Flemming, Nora J Fischenich, Benedikt S Saller, Oliver Gorka, Steffen Renner, Claudia Agarinis, Christian N Parker, Andreas Boettcher, Christopher J Farady, Rebecca Kesselring, Christopher Berlin, Rolf Backofen, Marta Rodriguez-Franco, Clemens Kreutz, Marco Prinz, Martina Tholen, Thomas Reinheckel, Thomas Ott, Christina J Groß, Philipp J Jost, Olaf Gross
Tyrosine kinase inhibitors can activate the NLRP3 inflammasome in myeloid cells through lysosomal damage and cell lysis. Science signaling 16 (768) (2023)
Emilia Neuwirt, Giovanni Magnani, Tamara Ćiković, Svenja Wöhrle, Larissa Fischer, Anna Kostina, Stephan Flemming, Nora J Fischenich, Benedikt S Saller, Oliver Gorka, Steffen Renner, Claudia Agarinis, Christian N Parker, Andreas Boettcher, Christopher J Farady, Rebecca Kesselring, Christopher Berlin, Rolf Backofen, Marta Rodriguez-Franco, Clemens Kreutz, Marco Prinz, Martina Tholen, Thomas Reinheckel, Thomas Ott, Christina J Groß, Philipp J Jost, Olaf Gross
Tyrosine kinase inhibitors can activate the NLRP3 inflammasome in myeloid cells through lysosomal damage and cell lysis. Science signaling 16 (768) (2023)
Aaron Bettecken, Lisa Heß, Lena Hölzen, Thomas Reinheckel
Dipeptidyl-Aminopeptidases 8 and 9 Regulate Autophagy and Tamoxifen Response in Breast Cancer Cells. Cells 12 (16) (2023)
Claudio Bussi, Tiaan Heunis, Enrica Pellegrino, Elliott M Bernard, Nourdine Bah, Mariana Silva Dos Santos, Pierre Santucci, Beren Aylan, Angela Rodgers, Antony Fearns, Julia Mitschke, Christopher Moore, James I MacRae, Maria Greco, Thomas Reinheckel, Matthias Trost, Maximiliano G Gutierrez
Lysosomal damage drives mitochondrial proteome remodelling and reprograms macrophage immunometabolism. Nature communications 13 (1) (2022)
Thomas Reinheckel, Martina Tholen
Low-level lysosomal membrane permeabilization for limited release and sublethal functions of cathepsin proteases in the cytosol and nucleus. FEBS open bio 12 (4) (2022)
Stephanie Ketterer, Julia Mitschke, Anett Ketscher, Manuel Schlimpert, Wilfried Reichardt, Natascha Baeuerle, Maria Elena Hess, Patrick Metzger, Melanie Börries, Christoph Peters, Bernd Kammerer, Tilman Brummer, Florian Steinberg, Thomas Reinheckel
Cathepsin D deficiency in mammary epithelium transiently stalls breast cancer by interference with mTORC1 signaling. Nature communications 11 (1) (2020)
Saara Hämälistö, Jonathan Lucien Stahl, Elena Favaro, Qing Yang, Bin Liu, Line Christoffersen, Ben Loos, Claudia Guasch Boldú, Johanna A Joyce, Thomas Reinheckel, Marin Barisic, Marja Jäättelä
Spatially and temporally defined lysosomal leakage facilitates mitotic chromosome segregation. Nature communications 11 (1) (2020)
María Alejandra Parigiani, Anett Ketscher, Sylvia Timme, Peter Bronsert, Manuel Schlimpert, Bernd Kammerer, Arnaud Jacquel, Paul Chaintreuil, Thomas Reinheckel
Conditional Gene Targeting Reveals Cell Type-Specific Roles of the Lysosomal Protease Cathepsin L in Mammary Tumor Progression. Cancers 12 (8) (2020)
Alejandro Gomez-Auli, Larissa Elisabeth Hillebrand, Daniel Christen, Sira Carolin Günther, Martin Lothar Biniossek, Christoph Peters, Oliver Schilling, Thomas Reinheckel
The secreted inhibitor of invasive cell growth CREG1 is negatively regulated by cathepsin proteases. Cellular and molecular life sciences : CMLS 78 (2) (2020)
Nadine Reischmann, Geoffroy Andrieux, Ricarda Herr, Thomas Reinheckel, Melanie Boerries, Tilman Brummer
BRAFV600E drives dedifferentiation in small intestinal and colonic organoids and cooperates with mutant p53 and Apc loss in transformation. Oncogene 39 (38) (2020)
Julia Mitschke, Ulrike C Burk, Thomas Reinheckel
The role of proteases in epithelial-to-mesenchymal cell transitions in cancer. Cancer metastasis reviews 38 (3) (2020)
Martin Köhler, Sophia Ehrenfeld, Sebastian Halbach, Manuel Lauinger, Ulrike Burk, Nadine Reischmann, Shuofei Cheng, Corinna Spohr, Franziska Maria Uhl, Natalie Köhler, Kathrin Ringwald, Sandra Braun, Christoph Peters, Robert Zeiser, Thomas Reinheckel, Tilman Brummer
B-Raf deficiency impairs tumor initiation and progression in a murine breast cancer model. Oncogene 38 (8) (2019)

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Publication Activity (10 Years)

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Thomas Reinheckel