Melanie Börries (M Boerries, Melanie Boerries)

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 86

Top Topics

Tyrosine Kinase

Immune Response

Top Venues

Nature communications

Science translational medicine

EMBO molecular medicine

This page only lists publications with an associated author ORCID identifier.

Publications

Janaki Manoja Vinnakota, Francesca Biavasco, Marius Schwabenland, Chintan Chhatbar, Rachael C Adams, Daniel Erny, Sandra Duquesne, Nadia El Khawanky, Dominik Schmidt, Viktor Fetsch, Alexander Zähringer, Henrike Salié, Dimitrios Athanassopoulos, Lukas M Braun, Nora R Javorniczky, Jenny N H G Ho, Katrin Kierdorf, Reinhard Marks, Ralph Wäsch, Federico Simonetta, Geoffroy Andrieux, Dietmar Pfeifer, Gianni Monaco, Christian M Capitini, Terry J Fry, Thomas Blank, Bruce R Blazar, Eva Maria Wagner-Drouet, Matthias Theobald, Clemens Sommer, Matthias Stelljes, Christian Reicherts, Astrid Jeibmann, Jens Schittenhelm, Camelia-Maria Monoranu, Andreas Rosenwald, Klaus Martin Kortüm, Leo Rasche, Hermann Einsele, Philipp T Meyer, Joachim Brumberg, Simon Völkl, Andreas Mackensen, Roland Coras, Michael von Bergwelt-Baildon, Nathalie L Albert, Laura M Bartos, Matthias Brendel, Adrien Holzgreve, Matthias Mack, Melanie Börries, Crystal L Mackall, Justus Duyster, Philipp Henneke, Josef Priller, Natalie Stickel, Felix L Strübing, Bertram Bengsch, Marco Ruella, Marion Subklewe, Louisa von Baumgarten, Saar Gill, Marco Prinz, Robert Zeiser
Targeting TGFβ-activated kinase-1 activation in microglia reduces CAR T immune effector cell-associated neurotoxicity syndrome. Nature cancer (2024)
Nadine Weinelt, Kaja Nicole Wächtershäuser, Gulustan Celik, Birte Jeiler, Isabelle Gollin, Laura Zein, Sonja Smith, Geoffroy Andrieux, Tonmoy Das, Jens Roedig, Leonard Feist, Björn Rotter, Melanie Börries, Francesco Pampaloni, Sjoerd J L van Wijk
LUBAC-mediated M1 Ub regulates necroptosis by segregating the cellular distribution of active MLKL. Cell death & disease 15 (1) (2024)
Julian Staniek, Tomas Kalina, Geoffroy Andrieux, Melanie Börries, Iga Janowska, Manuel Fuentes, Paula Díez, Marina Bakardjieva, Jitka Stancikova, Jan Raabe, Julika Neumann, Sabine Schwenk, Leonardo Arpesella, Jan Stuchly, Vladimir Benes, Rodrigo García-Valiente, Jonatan Fernandez-Garcia, Rita Carsetti, Eva Piano Mortari, Albert Català, Oscar de la Calle, Georgios Sogkas, Bénédicte Neven, Frédéric Rieux-Laucat, Aude Magerus, Marta Aboza Garcia, Peter Olbrich, Reinhard E Voll, Laia Alsina, Luis M. Allende, Luis Ignacio González-Granado, Chiara Böhler, Jens Thiel, Nils Venhoff, Raquel Lorenzetti, Klaus Warnatz, Susanne Unger, Maximilian Seidl, Dirk Mielenz, Pascal Schneider, Stephan Ehl, Anne Rensing-Ehl, Cristian Roberto Smulski, Marta Rizzi
Non-apoptotic FAS signaling controls mTOR activation and extrafollicular maturation in human B cells. Science immunology 9 (91) (2024)
Kristina Maas-Bauer, Anna-Verena Stell, Kai-Li Yan, Enrique de Vega, Janaki Manoja Vinnakota, Susanne Unger, Nicolas Núñez, Johana Norona, Nana Talvard-Balland, Stefanie Koßmann, Carsten Schwan, Christoph Cornelius Miething, Uta S Martens, Khalid Shoumariyeh, Rosa P Nestor, Sandra Duquesne, Kathrin Hanke, Michal Rackiewicz, Zehan Hu, Nadia El Khawanky, Sanaz Taromi, Hana Andrlova, Hemin Faraidun, Stefanie Walter, Dietmar Pfeifer, Marie Follo, Johannes Waldschmidt, Wolfgang Melchinger, Michael Rassner, Claudia Wehr, Annette Schmitt-Graeff, Sebastian Halbach, James K Liao, Georg Häcker, Tilman Brummer, Joern Dengjel, Geoffroy Andrieux, Robert Grosse, Sonia Tugues, Bruce R Blazar, Burkhard Becher, Melanie Börries, Robert Zeiser
ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease. Nature communications 15 (1) (2024)
Kristina Maas-Bauer, Anna-Verena Stell, Kai-Li Yan, Enrique de Vega, Janaki Manoja Vinnakota, Susanne Unger, Nicolas Núñez, Johana Norona, Nana Talvard-Balland, Stefanie Koßmann, Carsten Schwan, Christoph Cornelius Miething, Uta S Martens, Khalid Shoumariyeh, Rosa P Nestor, Sandra Duquesne, Kathrin Hanke, Michal Rackiewicz, Zehan Hu, Nadia El Khawanky, Sanaz Taromi, Hana Andrlova, Hemin Faraidun, Stefanie Walter, Dietmar Pfeifer, Marie Follo, Johannes Waldschmidt, Wolfgang Melchinger, Michael Rassner, Claudia Wehr, Annette Schmitt-Graeff, Sebastian Halbach, James K Liao, Georg Häcker, Tilman Brummer, Joern Dengjel, Geoffroy Andrieux, Robert Grosse, Sonia Tugues, Bruce R Blazar, Burkhard Becher, Melanie Börries, Robert Zeiser
ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease. Nature communications 15 (1) (2024)
Marie Czech, Sophia Schneider, Nina Peltokangas, Nadia El Khawanky, Sakhila Ghimire, Geoffroy Andrieux, Jan Hülsdünker, Máté Krausz, Michele Proietti, Lukas M Braun, Tamina Rückert, Marlene Langenbach, Dominik Schmidt, Ina Martin, Valentin Wenger, Enrique de Vega, Eileen Haring, Mohsen Pourjam, Dietmar Pfeifer, Annette Schmitt-Graeff, Bodo Grimbacher, Konrad Aumann, Brigitte Kircher, Herbert Tilg, Manuela Raffatellu, Erik Thiele Orberg, Georg Häcker, Justus Duyster, Natalie Stickel, Ernst Holler, David Nachbaur, Melanie Börries, Romana Raphaela Gerner, Dominic Grün, Robert Zeiser
Lipocalin-2 expression identifies an intestinal regulatory neutrophil population during acute graft-versus-host disease. Science translational medicine 16 (735) (2024)
Janaki Manoja Vinnakota, Rachael C Adams, Dimitrios Athanassopoulos, Dominik Schmidt, Francesca Biavasco, Alexander Zähringer, Daniel Erny, Marius Schwabenland, Marlene Langenbach, Valentin Wenger, Henrike Salié, James R Cook, Omar Mossad, Geoffroy Andrieux, Rick Dersch, Sebastian Rauer, Sandra Duquesne, Gianni Monaco, Phillipp Wolf, Thomas Blank, Philipp Häne, Melanie Greter, Burkhard Becher, Philipp Henneke, Dietmar Pfeifer, Bruce R Blazar, Justus Duyster, Melanie Börries, Natalie Stickel, Chintan M Chhatbar, Bertram Bengsch, Marco Prinz, Robert Zeiser
Anti-PD-1 cancer immunotherapy induces central nervous system immune-related adverse events by microglia activation. Science translational medicine 16 (751) (2024)
Janaki Manoja Vinnakota, Francesca Biavasco, Marius Schwabenland, Chintan Chhatbar, Rachael C Adams, Daniel Erny, Sandra Duquesne, Nadia El Khawanky, Dominik Schmidt, Viktor Fetsch, Alexander Zähringer, Henrike Salié, Dimitrios Athanassopoulos, Lukas M Braun, Nora R Javorniczky, Jenny N H G Ho, Katrin Kierdorf, Reinhard Marks, Ralph Wäsch, Federico Simonetta, Geoffroy Andrieux, Dietmar Pfeifer, Gianni Monaco, Christian M Capitini, Terry J Fry, Thomas Blank, Bruce R Blazar, Eva Maria Wagner-Drouet, Matthias Theobald, Clemens Sommer, Matthias Stelljes, Christian Reicherts, Astrid Jeibmann, Jens Schittenhelm, Camelia-Maria Monoranu, Andreas Rosenwald, Klaus Martin Kortüm, Leo Rasche, Hermann Einsele, Philipp T Meyer, Joachim Brumberg, Simon Völkl, Andreas Mackensen, Roland Coras, Michael von Bergwelt-Baildon, Nathalie L Albert, Laura M Bartos, Matthias Brendel, Adrien Holzgreve, Matthias Mack, Melanie Börries, Crystal L Mackall, Justus Duyster, Philipp Henneke, Josef Priller, Natalie Stickel, Felix L Strübing, Bertram Bengsch, Marco Ruella, Marion Subklewe, Louisa von Baumgarten, Saar Gill, Marco Prinz, Robert Zeiser
Targeting TGFβ-activated kinase-1 activation in microglia reduces CAR T immune effector cell-associated neurotoxicity syndrome. Nature cancer 5 (8) (2024)
Susanne Kessler, Bradly Burke, Geoffroy Andrieux, Jan Schinköthe, Lea Hamberger, Johannes Kacza, Shijun Zhan, Clara Reasoner, Taru S Dutt, Maria Kaukab Osman, Marcela Henao-Tamayo, Julian Staniek, Jose Francisco Villena Ossa, Dalit T Frank, Wenjun Ma, Reiner Ulrich, Toni Cathomen, Melanie Börries, Marta Rizzi, Martin Beer, Martin Schwemmle, Peter Reuther, Tony Schountz, Kevin Ciminski
Deciphering bat influenza H18N11 infection dynamics in male Jamaican fruit bats on a single-cell level. Nature communications 15 (1) (2024)
Abdul Moeed, Nico Thilmany, Frederic Beck, Bhagya K Puthussery, Noemi Ortmann, Aladin Haimovici, Mohamed Tarek Badr, Elham Bavafaye Haghighi, Melanie Börries, Rupert Öllinger, Roland Rad, Susanne Kirschnek, Ian Edward Gentle, Sainitin Donakonda, Philipp P Petric, Jonas F Hummel, Elisabeth Pfaffendorf, Paola Zanetta, Christoph Schell, Martin Schwemmle, Arnim Weber, Georg Häcker
The Caspase-Activated DNase drives inflammation and contributes to defense against viral infection. Cell death and differentiation (2024)
Susanne Kessler, Bradly Burke, Geoffroy Andrieux, Jan Schinköthe, Lea Hamberger, Johannes Kacza, Shijun Zhan, Clara Reasoner, Taru S Dutt, Maria Kaukab Osman, Marcela Henao-Tamayo, Julian Staniek, Jose Francisco Villena Ossa, Dalit T Frank, Wenjun Ma, Reiner Ulrich, Toni Cathomen, Melanie Börries, Marta Rizzi, Martin Beer, Martin Schwemmle, Peter Reuther, Tony Schountz, Kevin Ciminski
Deciphering bat influenza H18N11 infection dynamics in male Jamaican fruit bats on a single-cell level. Nature communications 15 (1) (2024)
Julia C Kuehn, Patrick Metzger, Nicolas Neidert, Uta Matysiak, Linda Gräßel, Ulrike Philipp, Sabine Bleul, Thomas Pauli, Julia Falkenstein, Henriette Bertemes, Stepan Cysar, Maria Elena Hess, Anna Verena Frey, Jesus Duque-Afonso, Elisabeth Schorb, Marcia Machein, Jürgen Beck, Oliver Schnell, Nikolas von Bubnoff, Anna L Illert, Christoph Peters, Tilman Brummer, Marco Prinz, Cornelius Miething, Heiko Becker, Silke Lassmann, Martin Werner, Melanie Börries, Justus Duyster, Dieter H Heiland, Roman Sankowski, Florian Scherer
Comprehensive genetic profiling and molecularly guided treatment for patients with primary CNS tumors. NPJ precision oncology 8 (1) (2024)
Julia C Kuehn, Patrick Metzger, Nicolas Neidert, Uta Matysiak, Linda Gräßel, Ulrike Philipp, Sabine Bleul, Thomas Pauli, Julia Falkenstein, Henriette Bertemes, Stepan Cysar, Maria Elena Hess, Anna Verena Frey, Jesus Duque-Afonso, Elisabeth Schorb, Marcia Machein, Jürgen Beck, Oliver Schnell, Nikolas von Bubnoff, Anna L Illert, Christoph Peters, Tilman Brummer, Marco Prinz, Cornelius Miething, Heiko Becker, Silke Lassmann, Martin Werner, Melanie Börries, Justus Duyster, Dieter H Heiland, Roman Sankowski, Florian Scherer
Comprehensive genetic profiling and molecularly guided treatment for patients with primary CNS tumors. NPJ precision oncology 8 (1) (2024)
Nadine Weinelt, Kaja Nicole Wächtershäuser, Gulustan Celik, Birte Jeiler, Isabelle Gollin, Laura Zein, Sonja Smith, Geoffroy Andrieux, Tonmoy Das, Jens Roedig, Leonard Feist, Björn Rotter, Melanie Börries, Francesco Pampaloni, Sjoerd J L van Wijk
LUBAC-mediated M1 Ub regulates necroptosis by segregating the cellular distribution of active MLKL. Cell death & disease 15 (1) (2024)
Janaki Manoja Vinnakota, Francesca Biavasco, Marius Schwabenland, Chintan Chhatbar, Rachael C Adams, Daniel Erny, Sandra Duquesne, Nadia El Khawanky, Dominik Schmidt, Viktor Fetsch, Alexander Zähringer, Henrike Salié, Dimitrios Athanassopoulos, Lukas M Braun, Nora R Javorniczky, Jenny N H G Ho, Katrin Kierdorf, Reinhard Marks, Ralph Wäsch, Federico Simonetta, Geoffroy Andrieux, Dietmar Pfeifer, Gianni Monaco, Christian M Capitini, Terry J Fry, Thomas Blank, Bruce R Blazar, Eva Maria Wagner-Drouet, Matthias Theobald, Clemens Sommer, Matthias Stelljes, Christian Reicherts, Astrid Jeibmann, Jens Schittenhelm, Camelia-Maria Monoranu, Andreas Rosenwald, Klaus Martin Kortüm, Leo Rasche, Hermann Einsele, Philipp T Meyer, Joachim Brumberg, Simon Völkl, Andreas Mackensen, Roland Coras, Michael von Bergwelt-Baildon, Nathalie L Albert, Laura M Bartos, Matthias Brendel, Adrien Holzgreve, Matthias Mack, Melanie Börries, Crystal L Mackall, Justus Duyster, Philipp Henneke, Josef Priller, Natalie Stickel, Felix L Strübing, Bertram Bengsch, Marco Ruella, Marion Subklewe, Louisa von Baumgarten, Saar Gill, Marco Prinz, Robert Zeiser
Targeting TGFβ-activated kinase-1 activation in microglia reduces CAR T immune effector cell-associated neurotoxicity syndrome. Nature cancer 5 (8) (2024)
Marie Czech, Sophia Schneider, Nina Peltokangas, Nadia El Khawanky, Sakhila Ghimire, Geoffroy Andrieux, Jan Hülsdünker, Máté Krausz, Michele Proietti, Lukas M Braun, Tamina Rückert, Marlene Langenbach, Dominik Schmidt, Ina Martin, Valentin Wenger, Enrique de Vega, Eileen Haring, Mohsen Pourjam, Dietmar Pfeifer, Annette Schmitt-Graeff, Bodo Grimbacher, Konrad Aumann, Brigitte Kircher, Herbert Tilg, Manuela Raffatellu, Erik Thiele Orberg, Georg Häcker, Justus Duyster, Natalie Stickel, Ernst Holler, David Nachbaur, Melanie Börries, Romana Raphaela Gerner, Dominic Grün, Robert Zeiser
Lipocalin-2 expression identifies an intestinal regulatory neutrophil population during acute graft-versus-host disease. Science translational medicine 16 (735) (2024)
Kristina Maas-Bauer, Anna-Verena Stell, Kai-Li Yan, Enrique de Vega, Janaki Manoja Vinnakota, Susanne Unger, Nicolas Núñez, Johana Norona, Nana Talvard-Balland, Stefanie Koßmann, Carsten Schwan, Christoph Cornelius Miething, Uta S Martens, Khalid Shoumariyeh, Rosa P Nestor, Sandra Duquesne, Kathrin Hanke, Michal Rackiewicz, Zehan Hu, Nadia El Khawanky, Sanaz Taromi, Hana Andrlova, Hemin Faraidun, Stefanie Walter, Dietmar Pfeifer, Marie Follo, Johannes Waldschmidt, Wolfgang Melchinger, Michael Rassner, Claudia Wehr, Annette Schmitt-Graeff, Sebastian Halbach, James K Liao, Georg Häcker, Tilman Brummer, Joern Dengjel, Geoffroy Andrieux, Robert Grosse, Sonia Tugues, Bruce R Blazar, Burkhard Becher, Melanie Börries, Robert Zeiser
ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease. Nature communications 15 (1) (2024)
Abdul Moeed, Nico Thilmany, Frederic Beck, Bhagya K Puthussery, Noemi Ortmann, Aladin Haimovici, Mohamed Tarek Badr, Elham Bavafaye Haghighi, Melanie Börries, Rupert Öllinger, Roland Rad, Susanne Kirschnek, Ian Edward Gentle, Sainitin Donakonda, Philipp P Petric, Jonas F Hummel, Elisabeth Pfaffendorf, Paola Zanetta, Christoph Schell, Martin Schwemmle, Arnim Weber, Georg Häcker
The Caspase-Activated DNase drives inflammation and contributes to defense against viral infection. Cell death and differentiation 31 (7) (2024)
Celina Tretter, Niklas de Andrade Krätzig, Matteo Pecoraro, Sebastian Lange, Philipp Seifert, Clara von Frankenberg, Johannes Untch, Gabriela Zuleger, Mathias Wilhelm, Daniel P Zolg, Florian S Dreyer, Eva Bräunlein, Thomas Engleitner, Sebastian Uhrig, Melanie Boxberg, Katja Steiger, Julia Slotta-Huspenina, Sebastian Ochsenreither, Nikolas von Bubnoff, Sebastian Bauer, Melanie Börries, Philipp J Jost, Kristina Schenck, Iska Dresing, Florian Bassermann, Helmut Friess, Daniel Reim, Konrad Grützmann, Katrin Pfütze, Barbara Klink, Evelin Schröck, Bernhard Haller, Bernhard Kuster, Matthias Mann, Wilko Weichert, Stefan Fröhling, Roland Rad, Michael Hiltensperger, Angela M Krackhardt
Author Correction: Proteogenomic analysis reveals RNA as a source for tumor-agnostic neoantigen identification. Nature communications 15 (1) (2024)
Kristina Maas-Bauer, Anna-Verena Stell, Kai-Li Yan, Enrique de Vega, Janaki Manoja Vinnakota, Susanne Unger, Nicolas Núñez, Johana Norona, Nana Talvard-Balland, Stefanie Koßmann, Carsten Schwan, Christoph Cornelius Miething, Uta S Martens, Khalid Shoumariyeh, Rosa P Nestor, Sandra Duquesne, Kathrin Hanke, Michal Rackiewicz, Zehan Hu, Nadia El Khawanky, Sanaz Taromi, Hana Andrlova, Hemin Faraidun, Stefanie Walter, Dietmar Pfeifer, Marie Follo, Johannes Waldschmidt, Wolfgang Melchinger, Michael Rassner, Claudia Wehr, Annette Schmitt-Graeff, Sebastian Halbach, James K Liao, Georg Häcker, Tilman Brummer, Joern Dengjel, Geoffroy Andrieux, Robert Grosse, Sonia Tugues, Bruce R Blazar, Burkhard Becher, Melanie Börries, Robert Zeiser
ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease. Nature communications 15 (1) (2024)
Laura Torella, Julia Klermund, Martin Bilbao-Arribas, Ibon Tamayo, Geoffroy Andrieux, Kay O Chmielewski, Africa Vales, Cristina Olagüe, Daniel Moreno-Luqui, Ivan Raimondi, Amaya Abad, Julen Torrens-Baile, Eduardo Salido, Maite Huarte, Mikel Hernaez, Melanie Börries, Toni Cathomen, Nerea Zabaleta, Gloria Gonzalez Aseguinolaza
Efficient and safe therapeutic use of paired Cas9-nickases for primary hyperoxaluria type 1. EMBO molecular medicine 16 (1) (2024)
Julian Staniek, Tomas Kalina, Geoffroy Andrieux, Melanie Börries, Iga Janowska, Manuel Fuentes, Paula Díez, Marina Bakardjieva, Jitka Stancikova, Jan Raabe, Julika Neumann, Sabine Schwenk, Leonardo Arpesella, Jan Stuchly, Vladimir Benes, Rodrigo García-Valiente, Jonatan Fernandez-Garcia, Rita Carsetti, Eva Piano Mortari, Albert Català, Oscar de la Calle, Georgios Sogkas, Bénédicte Neven, Frédéric Rieux-Laucat, Aude Magerus, Marta Aboza Garcia, Peter Olbrich, Reinhard E Voll, Laia Alsina, Luis M. Allende, Luis Ignacio González-Granado, Chiara Böhler, Jens Thiel, Nils Venhoff, Raquel Lorenzetti, Klaus Warnatz, Susanne Unger, Maximilian Seidl, Dirk Mielenz, Pascal Schneider, Stephan Ehl, Anne Rensing-Ehl, Cristian Roberto Smulski, Marta Rizzi
Non-apoptotic FAS signaling controls mTOR activation and extrafollicular maturation in human B cells. Science immunology 9 (91) (2024)
Abdul Moeed, Nico Thilmany, Frederic Beck, Bhagya K Puthussery, Noemi Ortmann, Aladin Haimovici, Mohamed Tarek Badr, Elham Bavafaye Haghighi, Melanie Börries, Rupert Öllinger, Roland Rad, Susanne Kirschnek, Ian Edward Gentle, Sainitin Donakonda, Philipp P Petric, Jonas F Hummel, Elisabeth Pfaffendorf, Paola Zanetta, Christoph Schell, Martin Schwemmle, Arnim Weber, Georg Häcker
The Caspase-Activated DNase drives inflammation and contributes to defense against viral infection. Cell death and differentiation 31 (7) (2024)
Laura Torella, Julia Klermund, Martin Bilbao-Arribas, Ibon Tamayo, Geoffroy Andrieux, Kay O Chmielewski, Africa Vales, Cristina Olagüe, Daniel Moreno-Luqui, Ivan Raimondi, Amaya Abad, Julen Torrens-Baile, Eduardo Salido, Maite Huarte, Mikel Hernaez, Melanie Börries, Toni Cathomen, Nerea Zabaleta, Gloria Gonzalez Aseguinolaza
Efficient and safe therapeutic use of paired Cas9-nickases for primary hyperoxaluria type 1. EMBO molecular medicine (2024)
Janaki Manoja Vinnakota, Francesca Biavasco, Marius Schwabenland, Chintan Chhatbar, Rachael C Adams, Daniel Erny, Sandra Duquesne, Nadia El Khawanky, Dominik Schmidt, Viktor Fetsch, Alexander Zähringer, Henrike Salié, Dimitrios Athanassopoulos, Lukas M Braun, Nora R Javorniczky, Jenny N H G Ho, Katrin Kierdorf, Reinhard Marks, Ralph Wäsch, Federico Simonetta, Geoffroy Andrieux, Dietmar Pfeifer, Gianni Monaco, Christian M Capitini, Terry J Fry, Thomas Blank, Bruce R Blazar, Eva Maria Wagner-Drouet, Matthias Theobald, Clemens Sommer, Matthias Stelljes, Christian Reicherts, Astrid Jeibmann, Jens Schittenhelm, Camelia-Maria Monoranu, Andreas Rosenwald, Klaus Martin Kortüm, Leo Rasche, Hermann Einsele, Philipp T Meyer, Joachim Brumberg, Simon Völkl, Andreas Mackensen, Roland Coras, Michael von Bergwelt-Baildon, Nathalie L Albert, Laura M Bartos, Matthias Brendel, Adrien Holzgreve, Matthias Mack, Melanie Börries, Crystal L Mackall, Justus Duyster, Philipp Henneke, Josef Priller, Natalie Stickel, Felix L Strübing, Bertram Bengsch, Marco Ruella, Marion Subklewe, Louisa von Baumgarten, Saar Gill, Marco Prinz, Robert Zeiser
Targeting TGFβ-activated kinase-1 activation in microglia reduces CAR T immune effector cell-associated neurotoxicity syndrome. Nature cancer (2024)
Nadine Weinelt, Kaja Nicole Wächtershäuser, Gulustan Celik, Birte Jeiler, Isabelle Gollin, Laura Zein, Sonja Smith, Geoffroy Andrieux, Tonmoy Das, Jens Roedig, Leonard Feist, Björn Rotter, Melanie Börries, Francesco Pampaloni, Sjoerd J L van Wijk
LUBAC-mediated M1 Ub regulates necroptosis by segregating the cellular distribution of active MLKL. Cell death & disease 15 (1) (2024)
Kristina Maas-Bauer, Anna-Verena Stell, Kai-Li Yan, Enrique de Vega, Janaki Manoja Vinnakota, Susanne Unger, Nicolas Núñez, Johana Norona, Nana Talvard-Balland, Stefanie Koßmann, Carsten Schwan, Christoph Cornelius Miething, Uta S Martens, Khalid Shoumariyeh, Rosa P Nestor, Sandra Duquesne, Kathrin Hanke, Michal Rackiewicz, Zehan Hu, Nadia El Khawanky, Sanaz Taromi, Hana Andrlova, Hemin Faraidun, Stefanie Walter, Dietmar Pfeifer, Marie Follo, Johannes Waldschmidt, Wolfgang Melchinger, Michael Rassner, Claudia Wehr, Annette Schmitt-Graeff, Sebastian Halbach, James K Liao, Georg Häcker, Tilman Brummer, Joern Dengjel, Geoffroy Andrieux, Robert Grosse, Sonia Tugues, Bruce R Blazar, Burkhard Becher, Melanie Börries, Robert Zeiser
ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease. Nature communications 15 (1) (2024)
Pablo Antón-García, Elham Bavafaye Haghighi, Katja Rose, Georg Vladimirov, Melanie Börries, Andreas Hecht
Correction: Antón-García et al. TGFβ1-Induced EMT in the MCF10A Mammary Epithelial Cell Line Model Is Executed Independently of SNAIL1 and ZEB1 but Relies on JUNB-Coordinated Transcriptional Regulation. Cancers 2023, 15 , 588. Cancers 16 (3) (2024)
Kristina Maas-Bauer, Anna-Verena Stell, Kai-Li Yan, Enrique de Vega, Janaki Manoja Vinnakota, Susanne Unger, Nicolas Núñez, Johana Norona, Nana Talvard-Balland, Stefanie Koßmann, Carsten Schwan, Christoph Cornelius Miething, Uta S Martens, Khalid Shoumariyeh, Rosa P Nestor, Sandra Duquesne, Kathrin Hanke, Michal Rackiewicz, Zehan Hu, Nadia El Khawanky, Sanaz Taromi, Hana Andrlova, Hemin Faraidun, Stefanie Walter, Dietmar Pfeifer, Marie Follo, Johannes Waldschmidt, Wolfgang Melchinger, Michael Rassner, Claudia Wehr, Annette Schmitt-Graeff, Sebastian Halbach, James K Liao, Georg Häcker, Tilman Brummer, Joern Dengjel, Geoffroy Andrieux, Robert Grosse, Sonia Tugues, Bruce R Blazar, Burkhard Becher, Melanie Börries, Robert Zeiser
ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease. Nature communications 15 (1) (2024)
Celina Tretter, Niklas de Andrade Krätzig, Matteo Pecoraro, Sebastian Lange, Philipp Seifert, Clara von Frankenberg, Johannes Untch, Gabriela Zuleger, Mathias Wilhelm, Daniel P Zolg, Florian S Dreyer, Eva Bräunlein, Thomas Engleitner, Sebastian Uhrig, Melanie Boxberg, Katja Steiger, Julia Slotta-Huspenina, Sebastian Ochsenreither, Nikolas von Bubnoff, Sebastian Bauer, Melanie Börries, Philipp J Jost, Kristina Schenck, Iska Dresing, Florian Bassermann, Helmut Friess, Daniel Reim, Konrad Grützmann, Katrin Pfütze, Barbara Klink, Evelin Schröck, Bernhard Haller, Bernhard Kuster, Matthias Mann, Wilko Weichert, Stefan Fröhling, Roland Rad, Michael Hiltensperger, Angela M Krackhardt
Author Correction: Proteogenomic analysis reveals RNA as a source for tumor-agnostic neoantigen identification. Nature communications 15 (1) (2024)
Laura Torella, Julia Klermund, Martin Bilbao-Arribas, Ibon Tamayo, Geoffroy Andrieux, Kay O Chmielewski, Africa Vales, Cristina Olagüe, Daniel Moreno-Luqui, Ivan Raimondi, Amaya Abad, Julen Torrens-Baile, Eduardo Salido, Maite Huarte, Mikel Hernaez, Melanie Börries, Toni Cathomen, Nerea Zabaleta, Gloria Gonzalez Aseguinolaza
Efficient and safe therapeutic use of paired Cas9-nickases for primary hyperoxaluria type 1. EMBO molecular medicine 16 (1) (2024)
Julia C Kuehn, Patrick Metzger, Nicolas Neidert, Uta Matysiak, Linda Gräßel, Ulrike Philipp, Sabine Bleul, Thomas Pauli, Julia Falkenstein, Henriette Bertemes, Stepan Cysar, Maria Elena Hess, Anna Verena Frey, Jesus Duque-Afonso, Elisabeth Schorb, Marcia Machein, Jürgen Beck, Oliver Schnell, Nikolas von Bubnoff, Anna L Illert, Christoph Peters, Tilman Brummer, Marco Prinz, Cornelius Miething, Heiko Becker, Silke Lassmann, Martin Werner, Melanie Börries, Justus Duyster, Dieter H Heiland, Roman Sankowski, Florian Scherer
Comprehensive genetic profiling and molecularly guided treatment for patients with primary CNS tumors. NPJ precision oncology 8 (1) (2024)
Laura Torella, Julia Klermund, Martin Bilbao-Arribas, Ibon Tamayo, Geoffroy Andrieux, Kay O Chmielewski, Africa Vales, Cristina Olagüe, Daniel Moreno-Luqui, Ivan Raimondi, Amaya Abad, Julen Torrens-Baile, Eduardo Salido, Maite Huarte, Mikel Hernaez, Melanie Börries, Toni Cathomen, Nerea Zabaleta, Gloria Gonzalez Aseguinolaza
Efficient and safe therapeutic use of paired Cas9-nickases for primary hyperoxaluria type 1. EMBO molecular medicine 16 (1) (2024)
Dominik Schmidt, Cornelia Endres, Rouven Hoefflin, Geoffroy Andrieux, Melissa Zwick, Nikolaos Karantzelis, Hans F Staehle, Janaki Manoja Vinnakota, Sandra Duquesne, Miriam Mozaffari Jovein, Dietmar Pfeifer, Heiko Becker, Bruce R Blazar, Alexander Zähringer, Justus Duyster, Tilman Brummer, Melanie Börries, Julian Baumeister, Khalid Shoumariyeh, Juan Li, Anthony R Green, Florian H Heidel, Michael Mints, Heike Luise Pahl, Nils Bastian Leimkühler, Natalie Stickel, Marcelo Augusto Szymanski de Toledo, Steffen Koschmieder, Robert Zeiser
Oncogenic Calreticulin Induces Immune Escape by Stimulating TGF-β Expression and Regulatory T Cell Expansion in the Bone Marrow Microenvironment. Cancer research (2024)
Abdul Moeed, Nico Thilmany, Frederic Beck, Bhagya K Puthussery, Noemi Ortmann, Aladin Haimovici, Mohamed Tarek Badr, Elham Bavafaye Haghighi, Melanie Börries, Rupert Öllinger, Roland Rad, Susanne Kirschnek, Ian Edward Gentle, Sainitin Donakonda, Philipp P Petric, Jonas F Hummel, Elisabeth Pfaffendorf, Paola Zanetta, Christoph Schell, Martin Schwemmle, Arnim Weber, Georg Häcker
The Caspase-Activated DNase drives inflammation and contributes to defense against viral infection. Cell death and differentiation 31 (7) (2024)
Julian Staniek, Tomas Kalina, Geoffroy Andrieux, Melanie Börries, Iga Janowska, Manuel Fuentes, Paula Díez, Marina Bakardjieva, Jitka Stancikova, Jan Raabe, Julika Neumann, Sabine Schwenk, Leonardo Arpesella, Jan Stuchly, Vladimir Benes, Rodrigo García-Valiente, Jonatan Fernandez-Garcia, Rita Carsetti, Eva Piano Mortari, Albert Català, Oscar de la Calle, Georgios Sogkas, Bénédicte Neven, Frédéric Rieux-Laucat, Aude Magerus, Marta Aboza Garcia, Peter Olbrich, Reinhard E Voll, Laia Alsina, Luis M. Allende, Luis Ignacio González-Granado, Chiara Böhler, Jens Thiel, Nils Venhoff, Raquel Lorenzetti, Klaus Warnatz, Susanne Unger, Maximilian Seidl, Dirk Mielenz, Pascal Schneider, Stephan Ehl, Anne Rensing-Ehl, Cristian Roberto Smulski, Marta Rizzi
Non-apoptotic FAS signaling controls mTOR activation and extrafollicular maturation in human B cells. Science immunology 9 (91) (2024)
Kristina Maas-Bauer, Anna-Verena Stell, Kai-Li Yan, Enrique de Vega, Janaki Manoja Vinnakota, Susanne Unger, Nicolas Núñez, Johana Norona, Nana Talvard-Balland, Stefanie Koßmann, Carsten Schwan, Christoph Cornelius Miething, Uta S Martens, Khalid Shoumariyeh, Rosa P Nestor, Sandra Duquesne, Kathrin Hanke, Michal Rackiewicz, Zehan Hu, Nadia El Khawanky, Sanaz Taromi, Hana Andrlova, Hemin Faraidun, Stefanie Walter, Dietmar Pfeifer, Marie Follo, Johannes Waldschmidt, Wolfgang Melchinger, Michael Rassner, Claudia Wehr, Annette Schmitt-Graeff, Sebastian Halbach, James K Liao, Georg Häcker, Tilman Brummer, Joern Dengjel, Geoffroy Andrieux, Robert Grosse, Sonia Tugues, Bruce R Blazar, Burkhard Becher, Melanie Börries, Robert Zeiser
ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease. Nature communications 15 (1) (2024)
Nadine Weinelt, Kaja Nicole Wächtershäuser, Gulustan Celik, Birte Jeiler, Isabelle Gollin, Laura Zein, Sonja Smith, Geoffroy Andrieux, Tonmoy Das, Jens Roedig, Leonard Feist, Björn Rotter, Melanie Börries, Francesco Pampaloni, Sjoerd J L van Wijk
LUBAC-mediated M1 Ub regulates necroptosis by segregating the cellular distribution of active MLKL. Cell death & disease 15 (1) (2024)
Janaki Manoja Vinnakota, Rachael C Adams, Dimitrios Athanassopoulos, Dominik Schmidt, Francesca Biavasco, Alexander Zähringer, Daniel Erny, Marius Schwabenland, Marlene Langenbach, Valentin Wenger, Henrike Salié, James R Cook, Omar Mossad, Geoffroy Andrieux, Rick Dersch, Sebastian Rauer, Sandra Duquesne, Gianni Monaco, Phillipp Wolf, Thomas Blank, Philipp Häne, Melanie Greter, Burkhard Becher, Philipp Henneke, Dietmar Pfeifer, Bruce R Blazar, Justus Duyster, Melanie Börries, Natalie Stickel, Chintan M Chhatbar, Bertram Bengsch, Marco Prinz, Robert Zeiser
Anti-PD-1 cancer immunotherapy induces central nervous system immune-related adverse events by microglia activation. Science translational medicine 16 (751) (2024)
Laura Torella, Julia Klermund, Martin Bilbao-Arribas, Ibon Tamayo, Geoffroy Andrieux, Kay O Chmielewski, Africa Vales, Cristina Olagüe, Daniel Moreno-Luqui, Ivan Raimondi, Amaya Abad, Julen Torrens-Baile, Eduardo Salido, Maite Huarte, Mikel Hernaez, Melanie Börries, Toni Cathomen, Nerea Zabaleta, Gloria Gonzalez Aseguinolaza
Efficient and safe therapeutic use of paired Cas9-nickases for primary hyperoxaluria type 1. EMBO molecular medicine (2024)
Pablo Antón-García, Elham Bavafaye Haghighi, Katja Rose, Georg Vladimirov, Melanie Börries, Andreas Hecht
Correction: Antón-García et al. TGFβ1-Induced EMT in the MCF10A Mammary Epithelial Cell Line Model Is Executed Independently of SNAIL1 and ZEB1 but Relies on JUNB-Coordinated Transcriptional Regulation. Cancers 2023, 15 , 588. Cancers 16 (3) (2024)
Laura Torella, Julia Klermund, Martin Bilbao-Arribas, Ibon Tamayo, Geoffroy Andrieux, Kay O Chmielewski, Africa Vales, Cristina Olagüe, Daniel Moreno-Luqui, Ivan Raimondi, Amaya Abad, Julen Torrens-Baile, Eduardo Salido, Maite Huarte, Mikel Hernaez, Melanie Börries, Toni Cathomen, Nerea Zabaleta, Gloria Gonzalez Aseguinolaza
Efficient and safe therapeutic use of paired Cas9-nickases for primary hyperoxaluria type 1. EMBO molecular medicine 16 (1) (2024)
Susanne Kessler, Bradly Burke, Geoffroy Andrieux, Jan Schinköthe, Lea Hamberger, Johannes Kacza, Shijun Zhan, Clara Reasoner, Taru S Dutt, Maria Kaukab Osman, Marcela Henao-Tamayo, Julian Staniek, Jose Francisco Villena Ossa, Dalit T Frank, Wenjun Ma, Reiner Ulrich, Toni Cathomen, Melanie Börries, Marta Rizzi, Martin Beer, Martin Schwemmle, Peter Reuther, Tony Schountz, Kevin Ciminski
Deciphering bat influenza H18N11 infection dynamics in male Jamaican fruit bats on a single-cell level. Nature communications 15 (1) (2024)
Amelie Jaeger, Sudheer Madan Mohan Gambheer, Xiaoyang Sun, Dmitry Chernyakov, Oleksandra Skorobohatko, Thomas M Mack, Sandra Kissel, Dietmar Pfeifer, Robert Zeiser, Paul Fisch, Geoffroy Andrieux, Daniela Bräuer-Hartmann, Marcus Bauer, Susann Schulze, Marie Follo, Melanie Börries, Nikolas von Bubnoff, Christoph Cornelius Miething, Jose Villacorta Hidalgo, Claudius Klein, Thomas Weber, Claudia Wickenhauser, Mascha Binder, Christine Dierks
Activated granulocytes and inflammatory cytokine signaling drive T-cell lymphoma progression and disease symptoms. Blood (2023)
Daniel Maier, Jörg Janne Vehreschild, Barbara Uhl, Sandra Meyer, Karin Berger-Thürmel, Melanie Börries, Rickmer F Braren, Viktor Gruenwald, Boris Hadaschik, Stefan Palm, Susanne Singer, Martin Stuschke, David Juárez, Pierre Delpy, Mohamed Lambarki, Michael Hummel, Cäcilia Engels, Stefanie Andreas, Nicola Gökbuget, Kristina Ihrig, Susen Burock, Dietmar Keune, Angelika Eggert, Ulrich Keilholz, Hagen Schulz, Daniel Büttner, Steffen Loeck, Mechthild Krause, Mirko Esins, Frank Ressing, Martin Schuler, Christian Brandts, Daniel P Brucker, Gabriele Husmann, Thomas Oellerich, Patrick Metzger, Frederik Voigt, Anna L Illert, Matthias Theobald, Thomas Kindler, Ursula Sudhof, Achim Reckmann, Felix Schwinghammer, Daniel Nasseh, Wilko Weichert, Michael von Bergwelt-Baildon, Michael Bitzer, Nisar Malek, Öznur Öner, Heike Bantel, Stefan Bartels, Joerg Haier, Raimund Ammann, Anja Franziska Schmidt, Bernd Guenther, Melanie Janning, Bernd Kasper, Sonja Loges, Stephan Stilgenbauer, Peter Kuhn, Eugen Tausch, Silvana Runow, Alexander Kerscher, Michael Neumann, Martin Breu, Martin Lablans, Hubert Serve
Profile of the multicenter cohort of the German Cancer Consortium's Clinical Communication Platform. European journal of epidemiology (2023)
Christopher Renner, Niklas Reimer, Jan Christoph, Hauke Busch, Patrick Metzger, Melanie Börries, Arsenij Ustjanzew, Dominik Boehm, Philipp Unberath
Extending cBioPortal for Therapy Recommendation Documentation in Molecular Tumor Boards: Development and Usability Study. JMIR medical informatics 11 (2023)
Ying Wu, Patricia M A Zehnle, Jovana Rajak, Naile Koleci, Geoffroy Andrieux, Lorena Gallego-Villar, Konrad Aumann, Melanie Börries, Charlotte M Niemeyer, Christian Flotho, Sheila Bohler, Miriam Erlacher
BH3 mimetics and azacitidine show synergistic effects on juvenile myelomonocytic leukemia. Leukemia (2023)
Marlene Langenbach, Sophie Giesler, Stefan Richtsfeld, Sara Costa-Pereira, Lukas Rindlisbacher, Tobias Wertheimer, Lukas M Braun, Geoffroy Andrieux, Sandra Duquesne, Dietmar Pfeifer, Nadine M Woessner, Hans D Menssen, Sanaz Taromi, Justus Duyster, Melanie Börries, Tilman Brummer, Bruce R Blazar, Susana Minguet, Patrick Turko, Mitchell Paul Levesque, Burkhard Becher, Robert Zeiser
MDM2 inhibition enhances immune checkpoint inhibitor efficacy by increasing IL-15 and MHC class II production. Molecular cancer research : MCR (2023)
Pablo Antón-García, Elham Bavafaye Haghighi, Katja Rose, Georg Vladimirov, Melanie Börries, Andreas Hecht
TGFβ1-Induced EMT in the MCF10A Mammary Epithelial Cell Line Model Is Executed Independently of SNAIL1 and ZEB1 but Relies on JUNB-Coordinated Transcriptional Regulation. Cancers 15 (2) (2023)
Manuel Lauinger, Daniel Christen, Rhena F U Klar, Carole Roubaty, Christoph E Heilig, Michael Stumpe, Jennifer J Knox, Nikolina Radulovich, Laura Tamblyn, Irene Y Xie, Peter Horak, Andrea Forschner, Michael Bitzer, Uwe A Wittel, Melanie Börries, Claudia R Ball, Christoph Heining, Hanno Glimm, Martina Fröhlich, Daniel Hübschmann, Steven Gallinger, Ralph Fritsch, Stefan Fröhling, Grainne M O'Kane, Joern Dengjel, Tilman Brummer
BRAF Δβ3-αC in-frame deletion mutants differ in their dimerization propensity, HSP90 dependence, and druggability. Science advances 9 (35) (2023)
Pablo Antón-García, Elham Bavafaye Haghighi, Katja Rose, Georg Vladimirov, Melanie Börries, Andreas Hecht
TGFβ1-Induced EMT in the MCF10A Mammary Epithelial Cell Line Model Is Executed Independently of SNAIL1 and ZEB1 but Relies on JUNB-Coordinated Transcriptional Regulation. Cancers 15 (2) (2023)
Michael Menzel, Stephan Ossowski, Sebastian Kral, Patrick Metzger, Peter Horak, Ralf Marienfeld, Melanie Börries, Steffen Wolter, Markus Ball, Olaf Neumann, Sorin Armeanu-Ebinger, Christopher Schroeder, Uta Matysiak, Hannah Goldschmid, Vincent Schipperges, Axel Fürstberger, Michael Allgäuer, Timo Eberhardt, Jakob Niewöhner, Andreas Blaumeiser, Carolin Ploeger, Tobias Bernd Haack, Timothy Kwang Yong Tay, Olga Kelemen, Thomas Pauli, Martina Kirchner, Klaus Kluck, Alexander Ott, Marcus Renner, Jakob Admard, Axel Gschwind, Silke Lassmann, Hans Kestler, Falko Fend, Anna Lena Illert, Martin Werner, Peter Möller, Thomas Theodor Werner Seufferlein, Nisar Malek, Peter Schirmacher, Stefan Fröhling, Daniel N Kazdal, Jan Budczies, Albrecht Stenzinger
Multicentric pilot study to standardize clinical whole exome sequencing (WES) for cancer patients. NPJ precision oncology 7 (1) (2023)
Joachim B Weis, Lucy Raphaela Wolf, Melanie Börries, Daniela Kassahn, Martin Boeker, Carolin Dresch
Identification of the Needs and Preferences of Patients With Cancer for the Development of a Clinic App: Qualitative Study. JMIR cancer 9 (2023)
Katrin Raute, Juliane Strietz, Maria Alejandra Parigiani, Geoffroy Andrieux, Oliver S Thomas, Klaus M Kistner, Marina Zintchenko, Peter Aichele, Maike Hofmann, Houjiang Zhou, Wilfried Weber, Melanie Börries, Mahima Swamy, Jochen Maurer, Susana Minguet
Breast Cancer Stem Cell-Derived Tumors Escape from γδ T-cell Immunosurveillance In Vivo by Modulating γδ T-cell Ligands. Cancer immunology research (2023)
Rubí M-H Velasco Cárdenas, Simon M Brandl, Ana Valeria Meléndez, Alexandra Emilia Schlaak, Annabelle Buschky, Timo Peters, Fabian Beier, Bryan Serrels, Sanaz Taromi, Katrin Raute, Simon Hauri, Matthias Gstaiger, Silke Lassmann, Johannes B Huppa, Melanie Börries, Geoffroy Andrieux, Bertram Bengsch, Wolfgang W A Schamel, Susana Minguet
Harnessing CD3 diversity to optimize CAR T cells. Nature immunology (2023)
Annika Nelde, Heiko Schuster, Jonas S Heitmann, Jens Bauer, Yacine Maringer, Melissa Zwick, Jens-Peter Volkmer, James Y Chen, Anna M Paczulla Stanger, Ariane Lehmann, Bismark Appiah, Melanie Märklin, Elke Rücker-Braun, Helmut R Salih, Malte Roerden, Sarah M Schroeder, Max-Felix Häring, Andreas Schlosser, Johannes Schetelig, Marc Schmitz, Melanie Börries, Natalie Stickel, Claudia Lengerke, Ravindra Majeti, Irving L Weissman, Hans-Georg Rammensee, Juliane Sarah Walz
Immune Surveillance of Acute Myeloid Leukemia Is Mediated by HLA-Presented Antigens on Leukemia Progenitor Cells. Blood cancer discovery (2023)
Amelie Jaeger, Sudheer Madan Mohan Gambheer, Xiaoyang Sun, Dmitry Chernyakov, Oleksandra Skorobohatko, Thomas M Mack, Sandra Kissel, Dietmar Pfeifer, Robert Zeiser, Paul Fisch, Geoffroy Andrieux, Daniela Bräuer-Hartmann, Marcus Bauer, Susann Schulze, Marie Follo, Melanie Börries, Nikolas von Bubnoff, Christoph Cornelius Miething, Jose Villacorta Hidalgo, Claudius Klein, Thomas Weber, Claudia Wickenhauser, Mascha Binder, Christine Dierks
Activated granulocytes and inflammatory cytokine signaling drive T-cell lymphoma progression and disease symptoms. Blood (2023)
Celina Tretter, Niklas de Andrade Krätzig, Matteo Pecoraro, Sebastian Lange, Philipp Seifert, Clara von Frankenberg, Johannes Untch, Gabriela Zuleger, Mathias Wilhelm, Daniel P Zolg, Florian S Dreyer, Eva Bräunlein, Thomas Engleitner, Sebastian Uhrig, Melanie Boxberg, Katja Steiger, Julia Slotta-Huspenina, Sebastian Ochsenreither, Nikolas von Bubnoff, Sebastian Bauer, Melanie Börries, Philipp J Jost, Kristina Schenck, Iska Dresing, Florian Bassermann, Helmut Friess, Daniel Reim, Konrad Grützmann, Katrin Pfütze, Barbara Klink, Evelin Schröck, Bernhard Haller, Bernhard Kuster, Matthias Mann, Wilko Weichert, Stefan Fröhling, Roland Rad, Michael Hiltensperger, Angela M Krackhardt
Proteogenomic analysis reveals RNA as a source for tumor-agnostic neoantigen identification. Nature communications 14 (1) (2023)
Roberto Ferrarese, Annalisa Izzo, Geoffroy Andrieux, Simon Lagies, Johanna Paulina Bartmuss, Anie Priscilla Masilamani, Alix Wasilenko, Daniela Osti, Stefania Faletti, Rana Schulzki, Shuai Yuan, Eva Kling, Valentino Ribecco, Dieter Henrik Heiland, Stefan Tholen, Marco Prinz, Giuliana Pelicci, Bernd Kammerer, Melanie Börries, Maria Stella Carro
ZBTB18 inhibits SREBP-dependent lipid synthesis by halting CTBPs and LSD1 activity in glioblastoma. Life science alliance 6 (1) (2022)
Lino Möhrmann, Maximilian Werner, Małgorzata Oleś, Andreas Mock, Sebastian Uhrig, Arne Jahn, Simon Kreutzfeldt, Martina Fröhlich, Barbara Hutter, Nagarajan Paramasivam, Daniela Richter, Katja Beck, Ulrike Winter, Katrin Pfütze, Christoph E Heilig, Veronica Teleanu, Daniel B Lipka, Marc Zapatka, Dorothea Hanf, Catrin List, Michael Allgäuer, Roland Penzel, Gina Rüter, Ivan Jelas, Rainer Hamacher, Johanna Falkenhorst, Sebastian Wagner, Christian H Brandts, Melanie Börries, Anna L Illert, Klaus H Metzeler, C Benedikt Westphalen, Alexander Desuki, Thomas Kindler, Gunnar Folprecht, Wilko Weichert, Benedikt Brors, Albrecht Stenzinger, Evelin Schröck, Daniel Hübschmann, Peter Horak, Christoph Heining, Stefan Fröhling, Hanno Glimm
Comprehensive genomic and epigenomic analysis in cancer of unknown primary guides molecularly-informed therapies despite heterogeneity. Nature communications 13 (1) (2022)
Tamina Rückert, Geoffroy Andrieux, Melanie Börries, Kathrin Hanke-Müller, Nadine M Woessner, Stephanie Doetsch, Christoph Schell, Konrad Aumann, Julia Kolter, Annette Schmitt-Graeff, Marcel Schiff, Lukas M Braun, Eileen Haring, Sandra Kissel, Benjamin A Siranosian, Ami Siddharth Bhatt, Peter Nordkild, Jan Wehkamp, Benjamin Anderschou Holbech Jensen, Susana Minguet, Justus Duyster, Robert Zeiser, Natalie Stickel
Human β-defensin 2 ameliorates acute GVHD by limiting ileal neutrophil infiltration and restraining T cell receptor signaling. Science translational medicine 14 (676) (2022)
Jenny N H G Ho, Dominik Schmidt, Theresa Lowinus, Jeongmin Ryoo, Elaine-Pashupati Dopfer, Nicolás Gonzalo Núñez, Sara Costa-Pereira, Cristina Toffalori, Marco Punta, Viktor Fetsch, Tobias Wertheimer, Marie-Claire Rittmann, Lukas M Braun, Marie Follo, Christelle Briere, Janaki Manoja Vinnakota, Marlene Langenbach, Felicitas Koppers, Khalid Shoumariyeh, Helena Engel, Tamina Rückert, Melanie Märklin, Samuel Holzmayer, Anna L Illert, Federica Magon, Geoffroy Andrieux, Sandra Duquesne, Dietmar Pfeifer, Julian Staniek, Marta Rizzi, Christoph Cornelius Miething, Natalie Stickel, Justus Duyster, Hans D Menssen, Melanie Börries, Joerg M Buescher, Nina Cabezas-Wallscheid, Bruce R Blazar, Petya Apostolova, Luca Vago, Erika L Pearce, Burkhard Becher, Robert Zeiser
Targeting MDM2 enhances antileukemia immunity after allogeneic transplantation via MHC-II and TRAIL-R1/2 upregulation. Blood 140 (10) (2022)
Tamina Rückert, Geoffroy Andrieux, Melanie Börries, Kathrin Hanke-Müller, Nadine M Woessner, Stephanie Doetsch, Christoph Schell, Konrad Aumann, Julia Kolter, Annette Schmitt-Graeff, Marcel Schiff, Lukas M Braun, Eileen Haring, Sandra Kissel, Benjamin A Siranosian, Ami Siddharth Bhatt, Peter Nordkild, Jan Wehkamp, Benjamin Anderschou Holbech Jensen, Susana Minguet, Justus Duyster, Robert Zeiser, Natalie Stickel
Human β-defensin 2 ameliorates acute GVHD by limiting ileal neutrophil infiltration and restraining T cell receptor signaling. Science translational medicine 14 (676) (2022)
Marion Flum, Severin Dicks, Yu-Hsiang Teng, Monika Schrempp, Alexander Nyström, Melanie Börries, Andreas Hecht
Canonical TGFβ signaling induces collective invasion in colorectal carcinogenesis through a Snail1- and Zeb1-independent partial EMT. Oncogene 41 (10) (2022)
Tamina Rückert, Geoffroy Andrieux, Melanie Börries, Kathrin Hanke-Müller, Nadine M Woessner, Stephanie Doetsch, Christoph Schell, Konrad Aumann, Julia Kolter, Annette Schmitt-Graeff, Marcel Schiff, Lukas M Braun, Eileen Haring, Sandra Kissel, Benjamin A Siranosian, Ami Siddharth Bhatt, Peter Nordkild, Jan Wehkamp, Benjamin Anderschou Holbech Jensen, Susana Minguet, Justus Duyster, Robert Zeiser, Natalie Stickel
Human β-defensin 2 ameliorates acute GVHD by limiting ileal neutrophil infiltration and restraining T cell receptor signaling. Science translational medicine 14 (676) (2022)
Franziska Maria Uhl, Sophia Chen, David O'Sullivan, Joy Edwards-Hicks, Gesa Richter, Eileen Haring, Geoffroy Andrieux, Sebastian Halbach, Petya Apostolova, Jörg Büscher, Sandra Duquesne, Wolfgang Melchinger, Barbara Sauer, Khalid Shoumariyeh, Annette Schmitt-Graeff, Marina Kreutz, Michael Lübbert, Justus Duyster, Tilman Brummer, Melanie Börries, Tobias Madl, Bruce R Blazar, Olaf Gross, Erika L Pearce, Robert Zeiser
Metabolic reprogramming of donor T cells enhances graft-versus-leukemia effects in mice and humans. Science translational medicine 12 (567) (2021)
Baerbel Keller, Valentina Strohmeier, Ina Harder, Susanne Unger, Kathryn J Payne, Geoffroy Andrieux, Melanie Börries, Peter Tobias Felixberger, Jonathan J M Landry, Alexandra Nieters, Anne Rensing-Ehl, Ulrich Salzer, Natalie Frede, Susanne Usadel, Roland Elling, Carsten Speckmann, Ina Hainmann, Elizabeth Ralph, Kimberley C Gilmour, Marjolein W J Wentink, Mirjam van der Burg, Hye Sun Kuehn, Sergio D Rosenzweig, Uwe Kölsch, Horst Von Bernuth, Petra Kaiser-Labusch, Florian Gothe, Sophie Hambleton, Alexandru Daniel Vlagea, Ana Garcia Garcia, Laia Alsina, Gašper Markelj, Tadej Avčin, Julia Vasconcelos, Margarida Guedes, Jing-Ya Ding, Cheng-Lung Ku, Bella Shadur, Danielle T Avery, Nils Venhoff, Jens Thiel, Heiko Becker, Lucía Erazo-Borrás, Claudia Milena Trujillo-Vargas, Jose Luis Franco, Claire Fieschi, Satoshi Okada, Paul E Gray, Gulbu Uzel, Jean Laurent Casanova, Manfred Fliegauf, Bodo Grimbacher, Hermann Eibel, Stephan Ehl, Reinhard E Voll, Marta Rizzi, Polina Stepensky, Vladimir Benes, Cindy S Ma, Claudia Bossen, Stuart G Tangye, Klaus Warnatz
The expansion of human T-bethighCD21low B cells is T cell dependent. Science immunology 6 (64) (2021)
Carla Regina, Ebrahem Hamed, Geoffroy Andrieux, Sina Angenendt, Michaela Schneider, Manching Ku, Marie Follo, Marco Wachtel, Eugene Ke, Ken Kikuchi, Anton G Henssen, Beat W Schäfer, Melanie Börries, Amy J Wagers, Charles Keller, Simone Hettmer
Negative correlation of single-cell PAX3:FOXO1 expression with tumorigenicity in rhabdomyosarcoma. Life science alliance 4 (9) (2021)
Eyleen Corrales, Ella Levit-Zerdoun, Patrick Metzger, Silke Kowar, Manching Ku, Tilman Brummer, Melanie Börries
Dynamic transcriptome analysis reveals signatures of paradoxical effect of vemurafenib on human dermal fibroblasts. Cell communication and signaling : CCS 19 (1) (2021)
Corinna Spohr, Teresa Poggio, Geoffroy Andrieux, Katharina Schönberger, Nina Cabezas-Wallscheid, Melanie Börries, Sebastian Halbach, Anna L Illert, Tilman Brummer
Gab2 deficiency prevents Flt3-ITD driven acute myeloid leukemia in vivo. Leukemia 36 (4) (2021)
Richa Sharma, Sushree S Sahoo, Masayoshi Honda, Sophie L Granger, Charnise Goodings, Louis Sanchez, Axel Künstner, Hauke Busch, Fabian Beier, Shondra M Pruett-Miller, Marcus Valentine, Alfonso Gonzalez Fernandez, Ti-Cheng Chang, Vincent Geli, Dimitri Churikov, Sandrine Hirschi, Victor B Pastor, Melanie Börries, Melchior Lauten, Charikleia Kelaidi, Marcin W Wlodarski, Megan Anne Cooper, Sarah K Nicholas, Jill Anne Rosenfeld, Sophia Polychronopoulou, Caroline Kannengiesser, Carole Saintomé, Charlotte M Niemeyer, Patrick Revy, Marc S Wold, Maria Spies, Miriam Erlacher, Stephane Coulon
Gain-of-Function Mutations in RPA1 Cause a Syndrome with Short Telomeres and Somatic Genetic Rescue. Blood (2021)
Patrick Frey, Antoine Devisme, Katja Rose, Monika Schrempp, Vivien Freihen, Geoffroy Andrieux, Melanie Börries, Andreas Hecht
SMAD4 mutations do not preclude epithelial-mesenchymal transition in colorectal cancer. Oncogene (2021)
Peter Horak, Christoph Heining, Simon Kreutzfeldt, Barbara Hutter, Andreas Mock, Jennifer Hüllein, Martina Fröhlich, Sebastian Uhrig, Arne Jahn, Andreas Rump, Laura Gieldon, Lino Möhrmann, Dorothea Hanf, Veronica Teleanu, Christoph E Heilig, Daniel B Lipka, Michael Allgäuer, Leo Ruhnke, Andreas Laßmann, Volker Endris, Olaf Neumann, Roland Penzel, Katja Beck, Daniela Richter, Ulrike Winter, Stephan Wolf, Katrin Pfütze, Christina Geörg, Bettina Meißburger, Ivo Buchhalter, Marinela Augustin, Walter E Aulitzky, Peter Hohenberger, Matthias Kroiss, Peter Schirmacher, Richard F Schlenk, Ulrich Keilholz, Frederick Klauschen, Gunnar Folprecht, Sebastian Bauer, Jens Thomas Siveke, Christian H Brandts, Thomas Kindler, Melanie Börries, Anna L Illert, Nikolas von Bubnoff, Philipp J Jost, Karsten Spiekermann, Michael Bitzer, Klaus Schulze-Osthoff, Christof von Kalle, Barbara Klink, Benedikt Brors, Albrecht Stenzinger, Evelin Schröck, Daniel Hübschmann, Wilko Weichert, Hanno Glimm, Stefan Fröhling
Comprehensive Genomic and Transcriptomic Analysis for Guiding Therapeutic Decisions in Patients with Rare Cancers. Cancer discovery 11 (11) (2021)
Rouven Hoefflin, Adriana Lazarou, Maria Elena Hess, Meike Reiser, Julius Wehrle, Patrick Metzger, Anna Verena Frey, Heiko Becker, Konrad Aumann, Kai Berner, Martin Boeker, Nico Buettner, Christine Dierks, Jesus Duque-Afonso, Michel Eisenblaetter, Thalia Erbes, Ralph Fritsch, Isabell Xiang Ge, Anna-Lena Geißler, Markus Grabbert, Steffen Heeg, Dieter Henrik Heiland, Simone Hettmer, Gian Kayser, Alexander Keller, Anita Kleiber, Alexandra Kutilina, Leman Mehmed, Frank Meiss, Philipp Poxleitner, Justyna Rawluk, Juri Ruf, Henning Schäfer, Florian Scherer, Khalid Shoumariyeh, Andreas Tzschach, Christoph Peters, Tilman Brummer, Martin Werner, Justus Duyster, Silke Lassmann, Cornelius Miething, Melanie Börries, Anna L Illert, Nikolas von Bubnoff
Transitioning the Molecular Tumor Board from Proof of Concept to Clinical Routine: A German Single-Center Analysis. Cancers 13 (5) (2021)
Lena Osswald, Shaima'a Hamarsheh, Franziska Maria Uhl, Geoffroy Andrieux, Claudius Klein, Christine Dierks, Sandra Duquesne, Lukas M Braun, Annette Schmitt-Graeff, Justus Duyster, Melanie Börries, Tilman Brummer, Robert Zeiser
Oncogenic KrasG12D Activation in the Nonhematopoietic Bone Marrow Microenvironment Causes Myelodysplastic Syndrome in Mice. Molecular cancer research : MCR 19 (9) (2021)
Felix Kind, Thomas F Fassbender, Geoffroy Andrieux, Melanie Börries, Philipp T Meyer, Juri Ruf
Early PSA Change after [ 177 Lu]PSMA-617 Radioligand Therapy as a Predicator of Biochemical Response and Overall Survival. Cancers 14 (1) (2021)
Ismael Sánchez-González, Anja Bobien, Christian Molnar, Simone Schmid, Michaela Strotbek, Melanie Börries, Hauke Busch, Monilola A Olayioye
miR-149 Suppresses Breast Cancer Metastasis by Blocking Paracrine Interactions with Macrophages. Cancer research 80 (6) (2020)
Janna Wenzel, Katja Rose, Elham Bavafaye Haghighi, Constanze Lamprecht, Gilles Rauen, Vivien Freihen, Rebecca Kesselring, Melanie Börries, Andreas Hecht
Loss of the nuclear Wnt pathway effector TCF7L2 promotes migration and invasion of human colorectal cancer cells. Oncogene 39 (19) (2020)
Stephanie Ketterer, Julia Mitschke, Anett Ketscher, Manuel Schlimpert, Wilfried Reichardt, Natascha Baeuerle, Maria Elena Hess, Patrick Metzger, Melanie Börries, Christoph Peters, Bernd Kammerer, Tilman Brummer, Florian Steinberg, Thomas Reinheckel
Cathepsin D deficiency in mammary epithelium transiently stalls breast cancer by interference with mTORC1 signaling. Nature communications 11 (1) (2020)
Stefanie Kreutmair, Cathrin Klingeberg, Teresa Poggio, Geoffroy Andrieux, Alexander Keller, Christoph Cornelius Miething, Marie Follo, Dietmar Pfeifer, Khalid Shoumariyeh, Claudia Lengerke, Irene Gonzalez-Menendez, Falko Fend, Robert Zeiser, Suzanne D Turner, Leticia Quintanilla-Martinez, Melanie Börries, Justus Duyster, Anna L Illert
Existence of reprogrammed lymphoma stem cells in a murine ALCL-like model. Leukemia 34 (12) (2020)
Sajib Chakraborty, Geoffroy Andrieux, A M Mahmudul Hasan, Musaddeque Ahmed, Md Ismail Hosen, Tania Rahman, M Anwar Hossain, Melanie Börries
Harnessing the tissue and plasma lncRNA-peptidome to discover peptide-based cancer biomarkers. Scientific reports 9 (1) (2019)
E Gladilin, S Ohse, Melanie Börries, Hauke Busch, C Xu, M Schneider, M Meister, R Eils
TGFβ-induced cytoskeletal remodeling mediates elevation of cell stiffness and invasiveness in NSCLC. Scientific reports 9 (1) (2019)
Hagen Klett, Lonny Jürgensen, Patrick Most, Martin Busch, Fabian Günther, Gergana Dobreva, Florian Leuschner, David Hassel, Hauke Busch, Melanie Börries
Delineating the Dynamic Transcriptome Response of mRNA and microRNA during Zebrafish Heart Regeneration. Biomolecules 9 (1) (2018)
Hagen Klett, Yesilda Balavarca, Reka Toth, Biljana Gigic, Nina Habermann, Dominique Scherer, Petra Schrotz-King, Alexis Ulrich, Peter Schirmacher, Esther Herpel, Hermann Brenner, Cornelia M Ulrich, Karin B Michels, Hauke Busch, Melanie Börries
Robust prediction of gene regulation in colorectal cancer tissues from DNA methylation profiles. Epigenetics 13 (4) (2018)
Ricarda Herr, Sebastian Halbach, Miriam Heizmann, Hauke Busch, Melanie Börries, Tilman Brummer
BRAF inhibition upregulates a variety of receptor tyrosine kinases and their downstream effector Gab2 in colorectal cancer cell lines. Oncogene 37 (12) (2018)
Justin Mastroianni, Natalie Stickel, Hana Andrlova, Kathrin Hanke, Wolfgang Melchinger, Sandra Duquesne, Dominik Schmidt, Martina Falk, Geoffroy Andrieux, Dietmar Pfeifer, Heide Dierbach, Annette Schmitt-Graeff, Frank Meiss, Melanie Börries, Robert Zeiser
miR-146a Controls Immune Response in the Melanoma Microenvironment. Cancer research 79 (1) (2018)