Timothy A Wencewicz

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 27

Top Venues

Communications biology

ACS infectious diseases

bioRxiv : the preprint server for biology

ACS chemical biology

Washington University in St. Louis

University of Notre Dame (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Washington University in St. Louis Jul 01 2013

United States

Assistant Professor :: Chemistry

Education History

University of Notre Dame Aug 20 2006 - Aug 20 2011

United States

PHD :: Chemistry and Biochemistry

Southeast Missouri State University Aug 20 2002 - May 20 2006

United States

BSC :: Chemistry

Publications

Syed Fardin Ahmed, Adam Balutowski, Jinping Yang, Timothy A Wencewicz, Andrew M Gulick
Expanding the substrate selectivity of the fimsbactin biosynthetic adenylation domain, FbsH. bioRxiv : the preprint server for biology (2024)
Syed Fardin Ahmed, Adam Balutowski, Jinping Yang, Timothy A Wencewicz, Andrew M Gulick
Expanding the substrate selectivity of the fimsbactin biosynthetic adenylation domain, FbsH. bioRxiv : the preprint server for biology (2024)
Kevin S Blake, Hirdesh Kumar, Anisha Loganathan, Emily E Williford, Luke Diorio-Toth, Yao-Peng Xue, Wai Kwan Tang, Tayte P Campbell, David D Chong, Steven Angtuaco, Timothy A Wencewicz, Niraj H Tolia, Gautam Dantas
Sequence-structure-function characterization of the emerging tetracycline destructase family of antibiotic resistance enzymes. Communications biology 7 (1) (2024)
Syed Fardin Ahmed, Adam Balutowski, Jinping Yang, Timothy A Wencewicz, Andrew M Gulick
Expanding the substrate selectivity of the fimsbactin biosynthetic adenylation domain, FbsH. bioRxiv : the preprint server for biology (2024)
Syed Fardin Ahmed, Adam Balutowski, Jinping Yang, Timothy A Wencewicz, Andrew M Gulick
Expanding the substrate selectivity of the fimsbactin biosynthetic adenylation domain, FbsH. bioRxiv : the preprint server for biology (2024)
Kevin S Blake, Hirdesh Kumar, Anisha Loganathan, Emily E Williford, Luke Diorio-Toth, Yao-Peng Xue, Wai Kwan Tang, Tayte P Campbell, David D Chong, Steven Angtuaco, Timothy A Wencewicz, Niraj H Tolia, Gautam Dantas
Sequence-structure-function characterization of the emerging tetracycline destructase family of antibiotic resistance enzymes. Communications biology 7 (1) (2024)
Kevin S Blake, Hirdesh Kumar, Anisha Loganathan, Emily E Williford, Luke Diorio-Toth, Yao-Peng Xue, Wai Kwan Tang, Tayte P Campbell, David D Chong, Steven Angtuaco, Timothy A Wencewicz, Niraj H Tolia, Gautam Dantas
Sequence-structure-function characterization of the emerging tetracycline destructase family of antibiotic resistance enzymes. Communications biology 7 (1) (2024)
Hirdesh Kumar, Emily E Williford, Kevin S Blake, Brett Virgin-Downey, Gautam Dantas, Timothy A Wencewicz, Niraj H Tolia
Publisher Correction: Structure of anhydrotetracycline-bound Tet(X6) reveals the mechanism for inhibition of type 1 tetracycline destructases. Communications biology 6 (1) (2023)
Emily E Williford, Caitlin M DeAngelo, Kevin S Blake, Hirdesh Kumar, Kendrick K Lam, Katherine V Jones, Niraj H Tolia, Gautam Dantas, Timothy A Wencewicz
Structure-Based Design of Bisubstrate Tetracycline Destructase Inhibitors That Block Flavin Redox Cycling. Journal of medicinal chemistry (2023)
Emily E Williford, Caitlin M DeAngelo, Kevin S Blake, Hirdesh Kumar, Kendrick K Lam, Katherine V Jones, Niraj H Tolia, Gautam Dantas, Timothy A Wencewicz
Structure-Based Design of Bisubstrate Tetracycline Destructase Inhibitors That Block Flavin Redox Cycling. Journal of medicinal chemistry 66 (6) (2023)
Jinping Yang, Victoria S Banas, Gerry S M Rivera, Timothy A Wencewicz
Siderophore Synthetase DesD Catalyzes N-to-C Condensation in Desferrioxamine Biosynthesis. ACS chemical biology (2023)
Hirdesh Kumar, Emily E Williford, Kevin S Blake, Brett Virgin-Downey, Gautam Dantas, Timothy A Wencewicz, Niraj H Tolia
Structure of anhydrotetracycline-bound Tet(X6) reveals the mechanism for inhibition of type 1 tetracycline destructases. Communications biology 6 (1) (2023)
Emily E Williford, Caitlin M DeAngelo, Kevin S Blake, Hirdesh Kumar, Kendrick K Lam, Katherine V Jones, Niraj H Tolia, Gautam Dantas, Timothy A Wencewicz
Structure-Based Design of Bisubstrate Tetracycline Destructase Inhibitors That Block Flavin Redox Cycling. Journal of medicinal chemistry 66 (6) (2023)
Hirdesh Kumar, Emily E Williford, Kevin S Blake, Brett Virgin-Downey, Gautam Dantas, Timothy A Wencewicz, Niraj H Tolia
Publisher Correction: Structure of anhydrotetracycline-bound Tet(X6) reveals the mechanism for inhibition of type 1 tetracycline destructases. Communications biology 6 (1) (2023)
Jinping Yang, Timothy A Wencewicz
In Vitro Reconstitution of Fimsbactin Biosynthesis from Acinetobacter baumannii . ACS chemical biology 17 (10) (2022)
Jinping Yang, Yunci Qi, Joshua A V Blodgett, Timothy A Wencewicz
Multifunctional P450 Monooxygenase CftA Diversifies the Clifednamide Pool through Tandem C-H Bond Activations. Journal of natural products 85 (1) (2022)
Hannah Valentino, David A Korasick, Tabbetha J Bohac, Justin A Shapiro, Timothy A Wencewicz, John J Tanner, Kendra Bufkin
Structural and Biochemical Characterization of the Flavin-Dependent Siderophore-Interacting Protein from Acinetobacter baumannii. ACS omega 6 (28) (2021)
Tabbetha J Bohac, Luting Fang, Victoria S Banas, Daryl E Giblin, Timothy A Wencewicz
Synthetic Mimics of Native Siderophores Disrupt Iron Trafficking in Acinetobacter baumannii. ACS infectious diseases 7 (8) (2021)
Andrew J Gasparrini, Jana L Markley, Hirdesh Kumar, Bin Wang, Luting Fang, Sidra Irum, Chanez T Symister, Meghan Wallace, Carey-Ann D Burnham, Saadia Andleeb, Niraj H Tolia, Timothy A Wencewicz, Gautam Dantas
Tetracycline-inactivating enzymes from environmental, human commensal, and pathogenic bacteria cause broad-spectrum tetracycline resistance. Communications biology 3 (1) (2020)
Tabbetha J Bohac, Luting Fang, Daryl E Giblin, Timothy A Wencewicz
Fimsbactin and Acinetobactin Compete for the Periplasmic Siderophore Binding Protein BauB in Pathogenic Acinetobacter baumannii. ACS chemical biology 14 (4) (2019)
Dale F Kreitler, Erin M Gemmell, Jason E Schaffer, Timothy A Wencewicz, Andrew M Gulick
The structural basis of N-acyl-α-amino-β-lactone formation catalyzed by a nonribosomal peptide synthetase. Nature communications 10 (1) (2019)
Jana L Markley, Luting Fang, Andrew J Gasparrini, Chanez T Symister, Hirdesh Kumar, Niraj H Tolia, Gautam Dantas, Timothy A Wencewicz
Semisynthetic Analogues of Anhydrotetracycline as Inhibitors of Tetracycline Destructase Enzymes. ACS infectious diseases 5 (4) (2019)
Gerry Sann M Rivera, Catherine R Beamish, Timothy A Wencewicz
Immobilized FhuD2 Siderophore-Binding Protein Enables Purification of Salmycin Sideromycins from Streptomyces violaceus DSM 8286. ACS infectious diseases 4 (5) (2018)
Daniel C Bailey, Tabbetha J Bohac, Justin A Shapiro, Daryl E Giblin, Timothy A Wencewicz, Andrew M Gulick
Crystal Structure of the Siderophore Binding Protein BauB Bound to an Unusual 2:1 Complex Between Acinetobactin and Ferric Iron. Biochemistry 57 (48) (2018)
Garrett J Patrick, Luting Fang, Jacob Schaefer, Sukrit Singh, Gregory R Bowman, Timothy A Wencewicz
Mechanistic Basis for ATP-Dependent Inhibition of Glutamine Synthetase by Tabtoxinine-β-lactam. Biochemistry 57 (1) (2017)
Tabbetha J Bohac, Justin A Shapiro, Timothy A Wencewicz
Rigid Oxazole Acinetobactin Analog Blocks Siderophore Cycling in Acinetobacter baumannii. ACS infectious diseases 3 (11) (2017)
Nathaniel P Endicott, Eries Lee, Timothy A Wencewicz
Structural Basis for Xenosiderophore Utilization by the Human Pathogen Staphylococcus aureus. ACS infectious diseases 3 (7) (2017)

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Publication Activity (10 Years)

Top Topics

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Timothy A Wencewicz