Timothy A Wencewicz

ORCID

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 20

Top Venues

ACS infectious diseases

Communications biology

ACS chemical biology

Journal of medicinal chemistry

Washington University in St. Louis

University of Notre Dame (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Washington University in St. Louis Jul 1o 2013

United States

Assistant Professor :: Chemistry

Education History

University of Notre Dame Aug 20o 2006 - Aug 20o 2011

United States

PHD :: Chemistry and Biochemistry

Publications

Hirdesh Kumar, Emily E Williford, Kevin S Blake, Brett Virgin-Downey, Gautam Dantas, Timothy A Wencewicz, Niraj H Tolia
Publisher Correction: Structure of anhydrotetracycline-bound Tet(X6) reveals the mechanism for inhibition of type 1 tetracycline destructases. Communications biology 6 (1) (2023)
Emily E Williford, Caitlin M DeAngelo, Kevin S Blake, Hirdesh Kumar, Kendrick K Lam, Katherine V Jones, Niraj H Tolia, Gautam Dantas, Timothy A Wencewicz
Structure-Based Design of Bisubstrate Tetracycline Destructase Inhibitors That Block Flavin Redox Cycling. Journal of medicinal chemistry (2023)
Emily E Williford, Caitlin M DeAngelo, Kevin S Blake, Hirdesh Kumar, Kendrick K Lam, Katherine V Jones, Niraj H Tolia, Gautam Dantas, Timothy A Wencewicz
Structure-Based Design of Bisubstrate Tetracycline Destructase Inhibitors That Block Flavin Redox Cycling. Journal of medicinal chemistry 66 (6) (2023)
Jinping Yang, Victoria S Banas, Gerry S M Rivera, Timothy A Wencewicz
Siderophore Synthetase DesD Catalyzes N-to-C Condensation in Desferrioxamine Biosynthesis. ACS chemical biology (2023)
Hirdesh Kumar, Emily E Williford, Kevin S Blake, Brett Virgin-Downey, Gautam Dantas, Timothy A Wencewicz, Niraj H Tolia
Structure of anhydrotetracycline-bound Tet(X6) reveals the mechanism for inhibition of type 1 tetracycline destructases. Communications biology 6 (1) (2023)
Emily E Williford, Caitlin M DeAngelo, Kevin S Blake, Hirdesh Kumar, Kendrick K Lam, Katherine V Jones, Niraj H Tolia, Gautam Dantas, Timothy A Wencewicz
Structure-Based Design of Bisubstrate Tetracycline Destructase Inhibitors That Block Flavin Redox Cycling. Journal of medicinal chemistry 66 (6) (2023)
Hirdesh Kumar, Emily E Williford, Kevin S Blake, Brett Virgin-Downey, Gautam Dantas, Timothy A Wencewicz, Niraj H Tolia
Publisher Correction: Structure of anhydrotetracycline-bound Tet(X6) reveals the mechanism for inhibition of type 1 tetracycline destructases. Communications biology 6 (1) (2023)
Jinping Yang, Timothy A Wencewicz
In Vitro Reconstitution of Fimsbactin Biosynthesis from Acinetobacter baumannii . ACS chemical biology 17 (10) (2022)
Jinping Yang, Yunci Qi, Joshua A V Blodgett, Timothy A Wencewicz
Multifunctional P450 Monooxygenase CftA Diversifies the Clifednamide Pool through Tandem C-H Bond Activations. Journal of natural products 85 (1) (2022)
Hannah Valentino, David A Korasick, Tabbetha J Bohac, Justin A Shapiro, Timothy A Wencewicz, John J Tanner, Kendra Bufkin
Structural and Biochemical Characterization of the Flavin-Dependent Siderophore-Interacting Protein from Acinetobacter baumannii. ACS omega 6 (28) (2021)
Tabbetha J Bohac, Luting Fang, Victoria S Banas, Daryl E Giblin, Timothy A Wencewicz
Synthetic Mimics of Native Siderophores Disrupt Iron Trafficking in Acinetobacter baumannii. ACS infectious diseases 7 (8) (2021)
Andrew J Gasparrini, Jana L Markley, Hirdesh Kumar, Bin Wang, Luting Fang, Sidra Irum, Chanez T Symister, Meghan Wallace, Carey-Ann D Burnham, Saadia Andleeb, Niraj H Tolia, Timothy A Wencewicz, Gautam Dantas
Tetracycline-inactivating enzymes from environmental, human commensal, and pathogenic bacteria cause broad-spectrum tetracycline resistance. Communications biology 3 (1) (2020)
Tabbetha J Bohac, Luting Fang, Daryl E Giblin, Timothy A Wencewicz
Fimsbactin and Acinetobactin Compete for the Periplasmic Siderophore Binding Protein BauB in Pathogenic Acinetobacter baumannii. ACS chemical biology 14 (4) (2019)
Dale F Kreitler, Erin M Gemmell, Jason E Schaffer, Timothy A Wencewicz, Andrew M Gulick
The structural basis of N-acyl-α-amino-β-lactone formation catalyzed by a nonribosomal peptide synthetase. Nature communications 10 (1) (2019)
Jana L Markley, Luting Fang, Andrew J Gasparrini, Chanez T Symister, Hirdesh Kumar, Niraj H Tolia, Gautam Dantas, Timothy A Wencewicz
Semisynthetic Analogues of Anhydrotetracycline as Inhibitors of Tetracycline Destructase Enzymes. ACS infectious diseases 5 (4) (2019)
Gerry Sann M Rivera, Catherine R Beamish, Timothy A Wencewicz
Immobilized FhuD2 Siderophore-Binding Protein Enables Purification of Salmycin Sideromycins from Streptomyces violaceus DSM 8286. ACS infectious diseases 4 (5) (2018)
Daniel C Bailey, Tabbetha J Bohac, Justin A Shapiro, Daryl E Giblin, Timothy A Wencewicz, Andrew M Gulick
Crystal Structure of the Siderophore Binding Protein BauB Bound to an Unusual 2:1 Complex Between Acinetobactin and Ferric Iron. Biochemistry 57 (48) (2018)
Garrett J Patrick, Luting Fang, Jacob Schaefer, Sukrit Singh, Gregory R Bowman, Timothy A Wencewicz
Mechanistic Basis for ATP-Dependent Inhibition of Glutamine Synthetase by Tabtoxinine-β-lactam. Biochemistry 57 (1) (2017)
Tabbetha J Bohac, Justin A Shapiro, Timothy A Wencewicz
Rigid Oxazole Acinetobactin Analog Blocks Siderophore Cycling in Acinetobacter baumannii. ACS infectious diseases 3 (11) (2017)
Nathaniel P Endicott, Eries Lee, Timothy A Wencewicz
Structural Basis for Xenosiderophore Utilization by the Human Pathogen Staphylococcus aureus. ACS infectious diseases 3 (7) (2017)

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Publication Activity (10 Years)

Top Topics

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Timothy A Wencewicz