Todd Holyoak

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 11

Top Topics

Structural Basis

Pseudomonas Aeruginosa

Top Venues

Nature communications

Protein science : a publication of the Protein Society

This page only lists publications with an associated author ORCID identifier.

Publications

Matthew J McLeod, Sarah A E Barwell, Todd Holyoak, Robert Edward Thorne
A structural perspective on the temperature-dependent activity of enzymes. bioRxiv : the preprint server for biology (2024)
Norman Tran, Sathish Dasari, Sarah A E Barwell, Matthew J McLeod, Subha Kalyaanamoorthy, Todd Holyoak, Aravindhan Ganesan
The H163A mutation unravels an oxidized conformation of the SARS-CoV-2 main protease. Nature communications 14 (1) (2023)
Matthew J McLeod, Norman Tran, Gregory D McCluskey, Tom D Gillis, Stephen L Bearne, Todd Holyoak
A metal dependent conformational change provides a structural basis for the inhibition of CTP synthase by gemcitabine-5'-triphosphate. Protein science : a publication of the Protein Society (2023)
Matthew J McLeod, Todd Holyoak
Biochemical, structural, and kinetic characterization of PP i -dependent phosphoenolpyruvate carboxykinase from Propionibacterium freudenreichii. Proteins (2023)
Matthew J McLeod, Norman Tran, Gregory D McCluskey, Tom D Gillis, Stephen L Bearne, Todd Holyoak
A metal dependent conformational change provides a structural basis for the inhibition of CTP synthase by gemcitabine-5'-triphosphate. Protein science : a publication of the Protein Society (2023)
Jasmina S Redzic, Jeremy Rahkola, Norman Tran, Todd Holyoak, Eunjeong Lee, Antonio Javier Martín-Galiano, Nancy Meyer, Hongjin Zheng, Elan Z Eisenmesser
A substrate-induced gating mechanism is conserved among Gram-positive IgA1 metalloproteases. Communications biology 5 (1) (2022)
Jonathan A Clinger, David W Mittan-Moreau, Matthew J McLeod, Todd Holyoak, Robert E Thorne
Millisecond mix-and-quench crystallography (MMQX) enables time-resolved studies of PEPCK with remote data collection. IUCrJ 8 (Pt 5) (2021)
Zhiming Wang, Jeremy Rahkola, Jasmina S Redzic, Ying-Chih Chi, Norman Tran, Todd Holyoak, Hongjin Zheng, Edward N Janoff, Elan Z Eisenmesser
Mechanism and inhibition of Streptococcus pneumoniae IgA1 protease. Nature communications 11 (1) (2020)
Matthew J Mcleod, Anthony P Krismanich, Abdeljalil Assoud, Gary I Dmitrienko, Todd Holyoak
Characterization of 3-[(Carboxymethyl)thio]picolinic Acid: A Novel Inhibitor of Phosphoenolpyruvate Carboxykinase. Biochemistry 58 (37) (2019)
Francisco Westermeier, Todd Holyoak, Rodrigo Gatica, Fernando Martínez, Marianne Negrón, Alejandro J Yáñez, Daniel Nahmias, Francisco J Nualart, Ian Burbulis, Romina Bertinat
Cytosolic phosphoenolpyruvate carboxykinase is expressed in α-cells from human and murine pancreas. Journal of cellular physiology 235 (1) (2019)
Danica S Cui, Aron Broom, Matthew J Mcleod, Elizabeth M Meiering, Todd Holyoak
Asymmetric Anchoring Is Required for Efficient Ω-Loop Opening and Closing in Cytosolic Phosphoenolpyruvate Carboxykinase. Biochemistry 56 (15) (2017)