Todd M Brusko (Todd Brusko)

Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 31

Top Topics

Cardiovascular Disease

Regulatory T Cells

Top Venues

Journal of immunology (Baltimore, Md. : 1950)

Scientific reports

Science immunology

This page only lists publications with an associated author ORCID identifier.

Publications

Joshua I Gray, Daniel P Caron, Steven B Wells, Rebecca Guyer, Peter A Szabo, Daniel B Rainbow, Can Ergen, Ksenia Rybkina, Marissa C Bradley, Rei Matsumoto, Kalpana Pethe, Masaru Kubota, Sarah A Teichmann, Joanne Louise Jones, Nir Yosef, Mark A Atkinson, Maigan A Brusko, Todd M Brusko, Thomas J Connors, Peter A Sims, Donna L Farber
Human γδ T cells in diverse tissues exhibit site-specific maturation dynamics across the life span. Science immunology 9 (96) (2024)
Rei Matsumoto, Joshua I Gray, Ksenia Rybkina, Hanna Oppenheimer, Lior Levy, Lilach M Friedman, Muhammad Khamaisi, Wenzhao Meng, Aaron M Rosenfeld, Rebecca S Guyer, Marissa C Bradley, David Chen, Mark A Atkinson, Todd M Brusko, Maigan Brusko, Thomas J Connors, Eline T Luning Prak, Uri Hershberg, Peter A Sims, Tomer Hertz, Donna L Farber
Induction of bronchus-associated lymphoid tissue is an early life adaptation for promoting human B cell immunity. Nature immunology (2023)
Matthew W Becker, Leeana D Peters, Thinzar Myint, Dylan Smurlick, Andrece Powell, Todd M Brusko, Edward A Phelps
Immune engineered extracellular vesicles to modulate T cell activation in the context of type 1 diabetes. Science advances 9 (22) (2023)
Melanie R Shapiro, Leeana D Peters, Matthew E Brown, Cecilia Cabello-Kindelan, Amanda L Posgai, Allison L Bayer, Todd M Brusko
Insulin-like Growth Factor-1 Synergizes with IL-2 to Induce Homeostatic Proliferation of Regulatory T Cells. Journal of immunology (Baltimore, Md. : 1950) (2023)
Jing Chen, Chao Liu, Anna V Chernatynskaya, Brittney Newby, Todd M Brusko, Yuan Xu, Jessie M Barra, Nadine N Morgan, Christopher Santarlas, Westley H Reeves, Hubert M Tse, Jennifer W Leiding, Clayton E Mathews
NADPH Oxidase 2-Derived Reactive Oxygen Species Promote CD8+ T Cell Effector Function. Journal of immunology (Baltimore, Md. : 1950) (2023)
Puchong Thirawatananond, Matthew E Brown, Lindsey K Sachs, Juan M Arnoletti, Wen-I Yeh, Amanda L Posgai, Melanie R Shapiro, Yi-Guang Chen, Todd M Brusko
Treg-specific CD226 Deletion Reduces Diabetes Incidence in NOD Mice by Improving Regulatory T Cell Stability. Diabetes (2023)
Daniel J Perry, Melanie R Shapiro, Sonya W Chamberlain, Irina Kusmarteva, Srikar Chamala, Leandro Balzano-Nogueira, Mingder Yang, Jason O Brant, Maigan Brusko, MacKenzie D Williams, Kieran M McGrail, James McNichols, Leeana D Peters, Amanda L Posgai, John S Kaddis, Clayton E Mathews, Clive H Wasserfall, Bobbie-Jo M Webb-Robertson, Martha Campbell-Thompson, Desmond Schatz, Carmella Evans-Molina, Alberto Pugliese, Patrick Concannon, Mark S Anderson, Michael S German, Chester E Chamberlain, Mark A Atkinson, Todd M Brusko
A genomic data archive from the Network for Pancreatic Organ donors with Diabetes. Scientific data 10 (1) (2023)
Alberto Pugliese, Daniel J Perry, Anh Nguyet Vu, Stephen S Rich, Mark A Atkinson, Desmond A Schatz, Bart O Roep, Todd M Brusko
Improving the Prediction of Type 1 Diabetes Across Ancestries. Diabetes care 45 (3) (2022)
Maria Jose Redondo, Sarah J Richardson, Daniel Perry, Charles G Minard, Alice L J Carr, Todd M Brusko, Irina Kusmarteva, Alberto Pugliese, Mark A Atkinson
Milder loss of insulin-containing islets in individuals with type 1 diabetes and type 2 diabetes-associated TCF7L2 genetic variants. Diabetologia 66 (1) (2022)
Gregory P Marshall, Judit Cserny, Chun-Wei Wang, Benjamin Looney, Amanda L Posgai, Rhonda Bacher, Benjamin G Keselowsky, Todd M Brusko
Biomaterials-based nanoparticles conjugated to regulatory T cells provide a modular system for localized delivery of pharmacotherapeutic agents. Journal of biomedical materials research. Part A 111 (2) (2022)
Melanie R Shapiro, Puchong Thirawatananond, Leeana Peters, Robert C Sharp, Similoluwa Ogundare, Amanda L Posgai, Daniel J Perry, Todd M Brusko
De-coding genetic risk variants in type 1 diabetes. Immunology and cell biology 99 (5) (2021)
Todd M Brusko, Holger A Russ, Cherie L Stabler
Strategies for durable β cell replacement in type 1 diabetes. Science (New York, N.Y.) 373 (6554) (2021)
Daniel J Perry, Leeana D Peters, Priya Saikumar Lakshmi, Lin Zhang, Zhao Han, Clive H Wasserfall, Clayton E Mathews, Mark A Atkinson, Todd M Brusko
Overexpression of the PTPN22 Autoimmune Risk Variant LYP-620W Fails to Restrain Human CD4+ T Cell Activation. Journal of immunology (Baltimore, Md. : 1950) 207 (3) (2021)
Grant Barker, Christiaan Leeuwenburgh, Todd M Brusko, Lyle Moldawer, Srinivasa T Reddy, Faheem W Guirgis
Lipid and Lipoprotein Dysregulation in Sepsis: Clinical and Mechanistic Insights into Chronic Critical Illness. Journal of clinical medicine 10 (8) (2021)
Maya Meimei Li Poon, Ksenia Rybkina, Yu Kato, Masaru Kubota, Rei Matsumoto, Nathaniel I Bloom, Zeli Zhang, Kathryn M Hastie, Alba Grifoni, Daniela Weiskopf, Steven B Wells, Basak B Ural, Nora Lam, Peter A Szabo, Pranay Dogra, Yoon Seung Lee, Joshua I Gray, Marissa C Bradley, Maigan A Brusko, Todd M Brusko, Erica Ollmann Saphire, Thomas J Connors, Alessandro Sette, Shane Crotty, Donna L Farber
SARS-CoV-2 infection generates tissue-localized immunological memory in humans. Science immunology 6 (65) (2021)
Puspa Thapa, Rebecca S Guyer, Alexander Y Yang, Christopher A Parks, Todd M Brusko, Maigan A Brusko, Thomas J Connors, Donna L Farber
Infant T cells are developmentally adapted for robust lung immune responses through enhanced T cell receptor signaling. Science immunology 6 (66) (2021)
Andrea Lin, Jasmine A Mack, Brittany S Bruggeman, Michael J Haller, Amanda L Posgai, Clive H Wasserfall, Todd M Brusko, Mark A Atkinson, Stephen E Gitelman, Peter A Gottlieb, Matthew J Gurka, Clayton E Mathews, Desmond A Schatz, Michael J Haller
Low-Dose ATG/GCSF in Established Type 1 Diabetes: A Five-Year Follow-up Report. Diabetes 70 (5) (2021)
Andrew S Nelson, Massimo Maddaloni, Jeffrey R Abbott, Carol Hoffman, Ali Akgul, Christina Ohland, Raad Z Gharaibeh, Christian Jobin, Todd M Brusko, David W Pascual
Oral therapy with colonization factor antigen I prevents development of type 1 diabetes in Non-obese Diabetic mice. Scientific reports 10 (1) (2020)
Craig A Beam, Clive Wasserfall, Alyssa Woodwyk, McKenzie Akers, Heather Rauch, Thomas Blok, Patrice Mason, Duncan Vos, Daniel J Perry, Todd M Brusko, Mark Peakman, Mark Atkinson
Synchronization of the Normal Human Peripheral Immune System: A Comprehensive Circadian Systems Immunology Analysis. Scientific reports 10 (1) (2020)
Simi Ahmed, Karen Cerosaletti, Eddie A James, Sarah Alice Long, Stuart Mannering, Cate Speake, Maki Nakayama, Timothy Tree, Bart O Roep, Kevan C Herold, Todd M Brusko
Standardizing T-Cell Biomarkers in Type 1 Diabetes: Challenges and Recent Advances. Diabetes 68 (7) (2020)
Cheng Ye, Benjamin E Low, Michael V Wiles, Todd M Brusko, David V Serreze, John P Driver
CD70 Inversely Regulates Regulatory T Cells and Invariant NKT Cells and Modulates Type 1 Diabetes in NOD Mice. Journal of immunology (Baltimore, Md. : 1950) 205 (7) (2020)
Emmi-Leena Ihantola, Henna Ilmonen, Anssi Kailaanmäki, Marja Rytkönen-Nissinen, Aurelien Azam, Bernard Maillère, Cecilia S Lindestam Arlehamn, Alessandro Sette, Keshav Motwani, Howard R Seay, Todd M Brusko, Olli H Laitinen, Riitta Veijola, Jorma Toppari, Jorma Ilonen, Tuure Kinnunen
Characterization of Proinsulin T Cell Epitopes Restricted by Type 1 Diabetes-Associated HLA Class II Molecules. Journal of immunology (Baltimore, Md. : 1950) 204 (9) (2020)
Ashby F Walker, Mark A Atkinson, Alexandra M Lee, Gina Aulisio, Todd M Brusko, Michael J Haller, Desmond A Schatz
Teaching Type 1 Diabetes: Creating Stakeholder Engagement in Biomedical Careers Through Undergraduate Research Curriculum. Medical science educator 30 (1) (2019)
Melanie R Shapiro, Clive H Wasserfall, Sean M McGrail, Amanda L Posgai, Rhonda Bacher, Andrew Muir, Michael J Haller, Desmond A Schatz, Johnna D Wesley, Matthias von Herrath, William A Hagopian, Cate Speake, Mark A Atkinson, Todd M Brusko
Insulin-Like Growth Factor Dysregulation Both Preceding and Following Type 1 Diabetes Diagnosis. Diabetes 69 (3) (2019)
Anton A Titov, Henry V Baker, Todd M Brusko, Eric S Sobel, Laurence Morel
Metformin Inhibits the Type 1 IFN Response in Human CD4+ T Cells. Journal of immunology (Baltimore, Md. : 1950) 203 (2) (2019)
Manuela Battaglia, Simi Ahmed, Mark S Anderson, Mark A Atkinson, Dorothy Becker, Polly J Bingley, Emanuele Bosi, Todd M Brusko, Linda A DiMeglio, Carmella Evans-Molina, Stephen E Gitelman, Carla J Greenbaum, Peter A Gottlieb, Kevan C Herold, Martin J Hessner, Olli H Laitinen, Michael J Haller, Jeffrey P Krischer, Sarah Alice Long, Markus Lundgren, Eoin F McKinney, Noel G Morgan, Richard D Oram, Tomi Pastinen, Michael C Peters, Alessandra Petrelli, Xiaoning Qian, Maria Jose Redondo, Bart O Roep, Desmond Schatz, David Skibinski, Mark Peakman
Introducing the Endotype Concept to Address the Challenge of Disease Heterogeneity in Type 1 Diabetes. Diabetes care 43 (1) (2019)
Hunter S Futch, Karen N McFarland, Brenda D Moore, M Zino Kuhn, Benoit I Giasson, Thomas B Ladd, Karen A Scott, Melanie R Shapiro, Rachel L Nosacka, Marshall S Goodwin, Yong Ran, Pedro E Cruz, Daniel H Ryu, Cara L Croft, Yona Levites, Christopher Janus, Paramita Chakrabarty, Andrew R Judge, Todd M Brusko, Annette D de Kloet, Eric G Krause, Griffin Golde
An anti-CRF antibody suppresses the HPA axis and reverses stress-induced phenotypes. The Journal of experimental medicine 216 (11) (2019)
Seung-Chul Choi, Anton A Titov, Georges Abboud, Howard R Seay, Todd M Brusko, Derry C Roopenian, Shahram Salek-Ardakani, Laurence Morel
Inhibition of glucose metabolism selectively targets autoreactive follicular helper T cells. Nature communications 9 (1) (2018)
Daniel J Perry, Clive H Wasserfall, Richard A Oram, MacKenzie D Williams, Amanda L Posgai, Andrew B Muir, Michael J Haller, Desmond A Schatz, Mark A Wallet, Clayton E Mathews, Mark A Atkinson, Todd M Brusko
Application of a Genetic Risk Score to Racially Diverse Type 1 Diabetes Populations Demonstrates the Need for Diversity in Risk-Modeling. Scientific reports 8 (1) (2018)
Andrew J Bryant, Borna Mehrad, Todd M Brusko, James D West, Lyle L Moldawer
Myeloid-Derived Suppressor Cells and Pulmonary Hypertension. International journal of molecular sciences 19 (8) (2018)
Seung-Chul Choi, Tarun E Hutchinson, Anton A Titov, Howard R Seay, Shiwu Li, Todd M Brusko, Byron P Croker, Shahram Salek-Ardakani, Laurence Morel
The Lupus Susceptibility Gene Pbx1 Regulates the Balance between Follicular Helper T Cell and Regulatory T Cell Differentiation. Journal of immunology (Baltimore, Md. : 1950) 197 (2) (2016)
Christopher A Fuhrman, Wen-I Yeh, Howard R Seay, Priya Saikumar Lakshmi, Gaurav Chopra, Lin Zhang, Daniel J Perry, Stephanie A McClymont, Mahesh Yadav, Maria-Cecilia Lopez, Henry V Baker, Ying Zhang, Yizheng Li, Maryann Whitley, David von Schack, Mark A Atkinson, Jeffrey A Bluestone, Todd M Brusko
Divergent Phenotypes of Human Regulatory T Cells Expressing the Receptors TIGIT and CD226. Journal of immunology (Baltimore, Md. : 1950) 195 (1) (2015)