Tomas Obsil (Tomáš Obšil)

ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 17

Top Venues

eLife

The FEBS journal

International journal of molecular sciences

Protein science : a publication of the Protein Society

Charles University, Faculty of Science

Charles University, Faculty of Science (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Charles University, Faculty of Science

Czechia

Head of department/Professor :: Department of Physical and Macromolecular Chemistry

Institute of Physiology of the Czech Academy of Sciences Oct 01 2002

Czechia

Scientist

NIDDK Laboratory of Molecular Biology Oct 01 1999 - Oct 01 2002

United States

Postdoctoral fellow :: Fred Dyda's Lab

Education History

Charles University, Faculty of Science Oct 01 1995 - Sep 30 1998

Czechia

PHD :: Department of Physical and Macromolecular Chemistry

Publications

Karolina Honzejkova, Dalibor Kosek, Veronika Obsilova, Tomas Obsil
The cryo-EM structure of ASK1 reveals an asymmetric architecture allosterically modulated by TRX1. eLife 13 (2024)
Karolina Honzejkova, Dalibor Kosek, Veronika Obsilova, Tomas Obsil
The cryo-EM structure of ASK1 reveals an asymmetric architecture allosterically modulated by TRX1. eLife 13 (2024)
Karolina Honzejkova, Dalibor Kosek, Veronika Obsilova, Tomas Obsil
The cryo-EM structure of ASK1 reveals an asymmetric architecture allosterically modulated by TRX1. eLife 13 (2024)
Olivia Petrvalska, Karolina Honzejkova, Nicola Koupilova, Petr Herman, Veronika Obsilova, Tomas Obsil
14-3-3 protein inhibits CaMKK1 by blocking the kinase active site with its last two C-terminal helices. Protein science : a publication of the Protein Society (2023)
Klara Kohoutova, Vojtěch Dočekal, Michael J Ausserlechner, Nora Kaiser, Andrej Tekel, Raju Mandal, Matej Horvath, Veronika Obsilova, Jan Vesely, Judith Hagenbuchner, Tomas Obsil
Lengthening the Guanidine-Aryl Linker of Phenylpyrimidinylguanidines Increases Their Potency as Inhibitors of FOXO3-Induced Gene Transcription. ACS omega 7 (38) (2022)
Raju Mandal, Klara Kohoutova, Olivia Petrvalska, Matej Horvath, Pavel Srb, Vaclav Veverka, Veronika Obsilova, Tomas Obsil
FOXO4 interacts with p53 TAD and CRD and inhibits its binding to DNA. Protein science : a publication of the Protein Society 31 (5) (2022)
Matej Horvath, Olivia Petrvalska, Petr Herman, Veronika Obsilova, Tomas Obsil
14-3-3 proteins inactivate DAPK2 by promoting its dimerization and protecting key regulatory phosphosites. Communications biology 4 (1) (2021)
Pavel Pohl, Rohit Joshi, Olivia Petrvalska, Tomas Obsil, Veronika Obsilova
14-3-3-protein regulates Nedd4-2 by modulating interactions between HECT and WW domains. Communications biology 4 (1) (2021)
Veronika Obsilova, Karolina Honzejkova, Tomas Obsil
Structural Insights Support Targeting ASK1 Kinase for Therapeutic Interventions. International journal of molecular sciences 22 (24) (2021)
Domenico Lentini Santo, Olivia Petrvalska, Veronika Obsilova, Christian Ottmann, Tomas Obsil
Stabilization of Protein-Protein Interactions between CaMKK2 and 14-3-3 by Fusicoccins. ACS chemical biology 15 (11) (2020)
Veronika Obsilova, Tomas Obsil
The 14-3-3 Proteins as Important Allosteric Regulators of Protein Kinases. International journal of molecular sciences 21 (22) (2020)
Dana Kalabova, Frantisek Filandr, Miroslava Alblova, Olivia Petrvalska, Matej Horvath, Petr Man, Tomas Obsil, Veronika Obsilova
14-3-3 protein binding blocks the dimerization interface of caspase-2. The FEBS journal 287 (16) (2020)
João Filipe Neves, Olivia Petrvalská, Francesco Bosica, François-Xavier Cantrelle, Hamida Merzougui, Gavin O'Mahony, Xavier Hanoulle, Tomas Obsil, Isabelle Landrieu
Phosphorylated full-length Tau interacts with 14-3-3 proteins via two short phosphorylated sequences, each occupying a binding groove of 14-3-3 dimer. The FEBS journal 288 (6) (2020)
Veronika Obsilova, Tomas Obsil
A new role for 14-3-3 protein in steroidogenesis. The FEBS journal 287 (18) (2020)
Judith Hagenbuchner, Veronika Obsilova, Teresa Kaserer, Nora Kaiser, Bettina Rass, Katarina Psenakova, Vojtech Docekal, Miroslava Alblova, Klara Kohoutova, Daniela Schuster, Tatsiana Aneichyk, Jan Vesely, Petra Obexer, Tomas Obsil, Michael J Ausserlechner
Modulating FOXO3 transcriptional activity by small, DBD-binding molecules. eLife 8 (2019)
Katarina Psenakova, Rozalie Hexnerova, Pavel Srb, Veronika Obsilova, Vaclav Veverka, Tomas Obsil
The redox-active site of thioredoxin is directly involved in apoptosis signal-regulating kinase 1 binding that is modulated by oxidative stress. The FEBS journal 287 (8) (2019)
Katarina Psenakova, Klara Kohoutova, Veronika Obsilova, Michael J Ausserlechner, Vaclav Veverka, Tomas Obsil
Forkhead Domains of FOXO Transcription Factors Differ in both Overall Conformation and Dynamics. Cells 8 (9) (2019)

Tomas Obsil.css-eqlu8i{font-size:small;padding-left:4px;} (Tomáš Obšil)

Publication Activity (10 Years)

Top Topics

Top Venues

Tomas Obsil (Tomáš Obšil)