Ulf Dettmer

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 30

Top Topics

Endoplasmic Reticulum

Mild Cognitive Impairment

Top Venues

NPJ Parkinson's disease

Journal of neurochemistry

bioRxiv : the preprint server for biology

This page only lists publications with an associated author ORCID identifier.

Publications

Silke Nuber, Xiaoqun Zhang, Thomas D McCaffery, Tim E Moors, Marie-Alexandre Adom, Wolf N Hahn, Dylan Martin, Maria Ericsson, Arati Tripathi, Ulf Dettmer, Per Svenningsson, Dennis J Selkoe
Author Correction: Generation of G51D and 3D mice reveals decreased α-synuclein tetramer-monomer ratios promote Parkinson's disease phenotypes. NPJ Parkinson's disease 10 (1) (2024)
Silke Nuber, Xiaoqun Zhang, Thomas D McCaffery, Tim E Moors, Marie-Alexandre Adom, Wolf N Hahn, Dylan Martin, Maria Ericsson, Arati Tripathi, Ulf Dettmer, Per Svenningsson, Dennis J Selkoe
Author Correction: Generation of G51D and 3D mice reveals decreased α-synuclein tetramer-monomer ratios promote Parkinson's disease phenotypes. NPJ Parkinson's disease 10 (1) (2024)
Andrew J White, Karis A Clark, Kellianne D Alexander, Nagendran Ramalingam, Tracy L Young-Pearse, Ulf Dettmer, Dennis J Selkoe, Gary P H Ho
A stem cell-based assay platform demonstrates alpha-synuclein dependent synaptic dysfunction in patient-derived cortical neurons. NPJ Parkinson's disease 10 (1) (2024)
Silke Nuber, Xiaoqun Zhang, Thomas D McCaffery, Tim E Moors, Marie-Alexandre Adom, Wolf N Hahn, Dylan Martin, Maria Ericsson, Arati Tripathi, Ulf Dettmer, Per Svenningsson, Dennis J Selkoe
Generation of G51D and 3D mice reveals decreased α-synuclein tetramer-monomer ratios promote Parkinson's disease phenotypes. NPJ Parkinson's disease 10 (1) (2024)
Peter Antony Barbuti, Cristina Guardia-Laguarta, Taekyung Yun, Zena K Chatila, Xena Flowers, Bruno Fr Santos, Simone B Larsen, Nobutaka Hattori, Elizabeth M Bradshaw, Ulf Dettmer, Saranna Fanning, Manon Vilas, Hasini Reddy, Andrew F Teich, Rejko Krüger, Estela Area-Gomez, Michelle Przedborski
The Role of Alpha-Synuclein in Synucleinopathy: Impact on Lipid Regulation at Mitochondria-ER Membranes. bioRxiv : the preprint server for biology (2024)
Silke Nuber, Xiaoqun Zhang, Thomas D McCaffery, Tim E Moors, Marie-Alexandre Adom, Wolf N Hahn, Dylan Martin, Maria Ericsson, Arathi Tripathi, Ulf Dettmer, Per Svenningsson, Dennis J Selkoe
Generation of G51D and 3D mice reveals decreased α-synuclein tetramer-monomer ratios promote Parkinson's disease phenotypes. NPJ Parkinson's disease 10 (1) (2024)
Silke Nuber, Xiaoqun Zhang, Thomas D McCaffery, Tim E Moors, Marie-Alexandre Adom, Wolf N Hahn, Dylan Martin, Maria Ericsson, Arati Tripathi, Ulf Dettmer, Per Svenningsson, Dennis J Selkoe
Generation of G51D and 3D mice reveals decreased α-synuclein tetramer-monomer ratios promote Parkinson's disease phenotypes. NPJ Parkinson's disease 10 (1) (2024)
Silke Nuber, Xiaoqun Zhang, Thomas D McCaffery, Tim E Moors, Marie-Alexandre Adom, Wolf N Hahn, Dylan Martin, Maria Ericsson, Arathi Tripathi, Ulf Dettmer, Per Svenningsson, Dennis J Selkoe
Generation of G51D and 3D mice reveals decreased α-synuclein tetramer-monomer ratios promote Parkinson's disease phenotypes. NPJ Parkinson's disease 10 (1) (2024)
Peter Antony Barbuti, Cristina Guardia-Laguarta, Taekyung Yun, Zena K Chatila, Xena Flowers, Bruno Fr Santos, Simone B Larsen, Nobutaka Hattori, Elizabeth M Bradshaw, Ulf Dettmer, Saranna Fanning, Manon Vilas, Hasini Reddy, Andrew F Teich, Rejko Krüger, Estela Area-Gomez, Michelle Przedborski
The Role of Alpha-Synuclein in Synucleinopathy: Impact on Lipid Regulation at Mitochondria-ER Membranes. bioRxiv : the preprint server for biology (2024)
Andrew J White, Karis A Clark, Kellianne D Alexander, Nagendran Ramalingam, Tracy L Young-Pearse, Ulf Dettmer, Dennis J Selkoe, Gary P H Ho
A stem cell-based assay platform demonstrates alpha-synuclein dependent synaptic dysfunction in patient-derived cortical neurons. NPJ Parkinson's disease 10 (1) (2024)
Silke Nuber, Xiaoqun Zhang, Thomas D McCaffery, Tim E Moors, Marie-Alexandre Adom, Wolf N Hahn, Dylan Martin, Maria Ericsson, Arathi Tripathi, Ulf Dettmer, Per Svenningsson, Dennis J Selkoe
Generation of G51D and 3D mice reveals decreased α-synuclein tetramer-monomer ratios promote Parkinson's disease phenotypes. NPJ Parkinson's disease 10 (1) (2024)
Silke Nuber, Xiaoqun Zhang, Thomas D McCaffery, Tim E Moors, Marie-Alexandre Adom, Wolf N Hahn, Dylan Martin, Maria Ericsson, Arati Tripathi, Ulf Dettmer, Per Svenningsson, Dennis J Selkoe
Generation of G51D and 3D mice reveals decreased α-synuclein tetramer-monomer ratios promote Parkinson's disease phenotypes. NPJ Parkinson's disease 10 (1) (2024)
Andrew J White, Karis A Clark, Kellianne D Alexander, Nagendran Ramalingam, Tracy L Young-Pearse, Ulf Dettmer, Dennis J Selkoe, Gary P H Ho
A stem cell-based assay platform demonstrates alpha-synuclein dependent synaptic dysfunction in patient-derived cortical neurons. NPJ Parkinson's disease 10 (1) (2024)
Tianyou Wang, Yingqi Sun, Ulf Dettmer
Astrocytes in Parkinson's Disease: From Role to Possible Intervention. Cells 12 (19) (2023)
Lisa Brontesi, Thibaut Imberdis, Nagendran Ramalingam, Ulf Dettmer
The effect of KTKEGV repeat motif and intervening ATVA sequence on α-synuclein solubility and assembly. Journal of neurochemistry (2023)
Nagendran Ramalingam, Shan-Xue Jin, Tim E Moors, Luis Fonseca-Ornelas, Kazuma Shimanaka, Shi Lei, Hugh P Cam, Aurelia Hays Watson, Lisa Brontesi, Lai Ding, Dinc Yasat Hacibaloglu, Haiyang Jiang, Se Joon Choi, Ellen Kanter, Lei Liu, Tim Bartels, Silke Nuber, David L Sulzer, Eugene V Mosharov, Weisheng V Chen, Shaomin Li, Dennis J Selkoe, Ulf Dettmer
Dynamic physiological α-synuclein S129 phosphorylation is driven by neuronal activity. NPJ Parkinson's disease 9 (1) (2023)
Nagendran Ramalingam, Shan-Xue Jin, Tim E Moors, Luis Fonseca-Ornelas, Kazuma Shimanaka, Shi Lei, Hugh P Cam, Aurelia Hays Watson, Lisa Brontesi, Lai Ding, Dinc Yasat Hacibaloglu, Haiyang Jiang, Se Joon Choi, Ellen Kanter, Lei Liu, Tim Bartels, Silke Nuber, David L Sulzer, Eugene V Mosharov, Weisheng V Chen, Shaomin Li, Dennis J Selkoe, Ulf Dettmer
Dynamic physiological α-synuclein S129 phosphorylation is driven by neuronal activity. NPJ Parkinson's disease 9 (1) (2023)
Lisa Brontesi, Thibaut Imberdis, Nagendran Ramalingam, Ulf Dettmer
The effects of KTKEGV repeat motif and intervening ATVA sequence on α-synuclein solubility and assembly. Journal of neurochemistry (2023)
Nagendran Ramalingam, Shan-Xue Jin, Tim E Moors, Luis Fonseca-Ornelas, Kazuma Shimanaka, Shi Lei, Hugh P Cam, Aurelia Hays Watson, Lisa Brontesi, Lai Ding, Dinc Yasat Hacibaloglu, Haiyang Jiang, Se Joon Choi, Ellen Kanter, Lei Liu, Tim Bartels, Silke Nuber, David L Sulzer, Eugene V Mosharov, Weisheng V Chen, Shaomin Li, Dennis J Selkoe, Ulf Dettmer
Dynamic physiological α-synuclein S129 phosphorylation is driven by neuronal activity. NPJ Parkinson's disease 9 (1) (2023)
Nagendran Ramalingam, Shan-Xue Jin, Tim E Moors, Luis Fonseca-Ornelas, Kazuma Shimanaka, Shi Lei, Hugh P Cam, Aurelia Hays Watson, Lisa Brontesi, Lai Ding, Dinc Yasat Hacibaloglu, Haiyang Jiang, Se Joon Choi, Ellen Kanter, Lei Liu, Tim Bartels, Silke Nuber, David L Sulzer, Eugene V Mosharov, Weisheng V Chen, Shaomin Li, Dennis J Selkoe, Ulf Dettmer
Dynamic physiological α-synuclein S129 phosphorylation is driven by neuronal activity. NPJ Parkinson's disease 9 (1) (2023)
Kazuma Shimanaka, Bryan Shi, Lisa Brontesi, Heba Alnakhala, Vidyashree Jayanthi, Kanagaraj Subramanian, Nagendran Ramalingam, Arati Tripathi, Ulf Dettmer
Adding hydrophobicity or positive charges to the cytosolic half of the α-synuclein 3-11 helix increases membrane association and S129 phosphorylation. FEBS letters (2023)
Nagendran Ramalingam, Lisa Brontesi, Shan-Xue Jin, Dennis J Selkoe, Ulf Dettmer
Dynamic reversibility of α-synuclein serine-129 phosphorylation is impaired in synucleinopathy models. EMBO reports (2023)
Lisa Brontesi, Thibaut Imberdis, Nagendran Ramalingam, Ulf Dettmer
The effects of KTKEGV repeat motif and intervening ATVA sequence on α-synuclein solubility and assembly. Journal of neurochemistry (2023)
Saranna Fanning, Haley Cirka, Jennifer L Thies, Jooyoung Jeong, Sarah M Niemi, Joon Yoon, Gary P H Ho, Julian Avila Pacheco, Ulf Dettmer, Lei Liu, Andrew T Chan, Kevin J Hodgetts, John N Hutchinson, Christina R Muratore, Guy A Caldwell, Kim A Caldwell, Dennis J Selkoe
Lipase regulation of cellular fatty acid homeostasis as a Parkinson's disease therapeutic strategy. NPJ Parkinson's disease 8 (1) (2022)
Luis Fonseca-Ornelas, Jonathan M S Stricker, Stephanie Soriano-Cruz, Beatrice Weykopf, Ulf Dettmer, Christina R Muratore, Clemens R Scherzer, Dennis J Selkoe
Parkinson-causing mutations in LRRK2 impair the physiological tetramerization of endogenous α-synuclein in human neurons. NPJ Parkinson's disease 8 (1) (2022)
Arati Tripathi, Saranna Fanning, Ulf Dettmer
Lipotoxicity Downstream of α-Synuclein Imbalance: A Relevant Pathomechanism in Synucleinopathies? Biomolecules 12 (1) (2021)
Kelly E Glajch, Tim E Moors, Yi Chen, Pascal A Bechade, Alice Y Nam, Molly M Rajsombath, Thomas D McCaffery, Ulf Dettmer, Andreas Weihofen, Warren D Hirst, Dennis J Selkoe, Silke Nuber
Wild-type GBA1 increases the α-synuclein tetramer-monomer ratio, reduces lipid-rich aggregates, and attenuates motor and cognitive deficits in mice. Proceedings of the National Academy of Sciences of the United States of America 118 (31) (2021)
Saranna Fanning, Dennis Selkoe, Ulf Dettmer
Vesicle trafficking and lipid metabolism in synucleinopathy. Acta neuropathologica 141 (4) (2020)
Elizabeth Terry-Kantor, Arati Tripathi, Thibaut Imberdis, Zachary M LaVoie, Gary P H Ho, Dennis Selkoe, Saranna Fanning, Nagendran Ramalingam, Ulf Dettmer
Rapid Alpha-Synuclein Toxicity in a Neural Cell Model and Its Rescue by a Stearoyl-CoA Desaturase Inhibitor. International journal of molecular sciences 21 (15) (2020)
Saranna Fanning, Dennis Selkoe, Ulf Dettmer
Parkinson's disease: proteinopathy or lipidopathy? NPJ Parkinson's disease 6 (2020)