Umeharu Ohto

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 22

Top Topics

Structural Basis

Top Venues

Nature communications

Nature structural & molecular biology

Communications biology

This page only lists publications with an associated author ORCID identifier.

Publications

Jinta Asami, Jae-Hyun Park, Yayoi Nomura, Chisa Kobayashi, Junki Mifune, Naito Ishimoto, Tomoko Uemura, Kehong Liu, Yumi Sato, Zhikuan Zhang, Masamichi Muramatsu, Takaji Wakita, David Drew, So Iwata, Toshiyuki Shimizu, Koichi Watashi, Sam-Yong Park, Norimichi Nomura, Umeharu Ohto
Structural basis of hepatitis B virus receptor binding. Nature structural & molecular biology (2024)
Yoshinori Hirano, Umeharu Ohto, Ikuyo Ichi, Ryota Sato, Kensuke Miyake, Toshiyuki Shimizu
Cryo-EM analysis reveals human SID-1 transmembrane family member 1 dynamics underlying lipid hydrolytic activity. Communications biology 7 (1) (2024)
Jinta Asami, Jae-Hyun Park, Yayoi Nomura, Chisa Kobayashi, Junki Mifune, Naito Ishimoto, Tomoko Uemura, Kehong Liu, Yumi Sato, Zhikuan Zhang, Masamichi Muramatsu, Takaji Wakita, David Drew, So Iwata, Toshiyuki Shimizu, Koichi Watashi, Sam-Yong Park, Norimichi Nomura, Umeharu Ohto
Structural basis of hepatitis B virus receptor binding. Nature structural & molecular biology 31 (3) (2024)
Yoshinori Hirano, Umeharu Ohto, Ikuyo Ichi, Ryota Sato, Kensuke Miyake, Toshiyuki Shimizu
Cryo-EM analysis reveals human SID-1 transmembrane family member 1 dynamics underlying lipid hydrolytic activity. Communications biology 7 (1) (2024)
Jinta Asami, Jae-Hyun Park, Yayoi Nomura, Chisa Kobayashi, Junki Mifune, Naito Ishimoto, Tomoko Uemura, Kehong Liu, Yumi Sato, Zhikuan Zhang, Masamichi Muramatsu, Takaji Wakita, David Drew, So Iwata, Toshiyuki Shimizu, Koichi Watashi, Sam-Yong Park, Norimichi Nomura, Umeharu Ohto
Structural basis of hepatitis B virus receptor binding. Nature structural & molecular biology 31 (3) (2024)
Yoshinori Hirano, Umeharu Ohto, Ikuyo Ichi, Ryota Sato, Kensuke Miyake, Toshiyuki Shimizu
Cryo-EM analysis reveals human SID-1 transmembrane family member 1 dynamics underlying lipid hydrolytic activity. Communications biology 7 (1) (2024)
Jinta Asami, Jae-Hyun Park, Yayoi Nomura, Chisa Kobayashi, Junki Mifune, Naito Ishimoto, Tomoko Uemura, Kehong Liu, Yumi Sato, Zhikuan Zhang, Masamichi Muramatsu, Takaji Wakita, David Drew, So Iwata, Toshiyuki Shimizu, Koichi Watashi, Sam-Yong Park, Norimichi Nomura, Umeharu Ohto
Structural basis of hepatitis B virus receptor binding. Nature structural & molecular biology 31 (3) (2024)
Kentaro Sakaniwa, Akiko Fujimura, Takuma Shibata, Hideki Shigematsu, Toru Ekimoto, Masaki Yamamoto, Mitsunori Ikeguchi, Kensuke Miyake, Umeharu Ohto, Toshiyuki Shimizu
TLR3 forms a laterally aligned multimeric complex along double-stranded RNA for efficient signal transduction. Nature communications 14 (1) (2023)
Atsuko Deguchi, Miho Watanabe-Takahashi, Taishi Mishima, Tsutomu Omori, Umeharu Ohto, Nobuto Arashiki, Fumio Nakamura, Kiyotaka Nishikawa, Yoshiro Maru
Novel multivalent S100A8 inhibitory peptides attenuate tumor progression and metastasis by inhibiting the TLR4-dependent pathway. Cancer gene therapy (2023)
Zhikuan Zhang, Takuma Shibata, Akiko Fujimura, Jiro Kitaura, Kensuke Miyake, Umeharu Ohto, Toshiyuki Shimizu
Structural basis for thioredoxin-mediated suppression of NLRP1 inflammasome. Nature (2023)
Kentaro Sakaniwa, Akiko Fujimura, Takuma Shibata, Hideki Shigematsu, Toru Ekimoto, Masaki Yamamoto, Mitsunori Ikeguchi, Kensuke Miyake, Umeharu Ohto, Toshiyuki Shimizu
TLR3 forms a laterally aligned multimeric complex along double-stranded RNA for efficient signal transduction. Nature communications 14 (1) (2023)
Kentaro Sakaniwa, Akiko Fujimura, Takuma Shibata, Hideki Shigematsu, Toru Ekimoto, Masaki Yamamoto, Mitsunori Ikeguchi, Kensuke Miyake, Umeharu Ohto, Toshiyuki Shimizu
TLR3 forms a laterally aligned multimeric complex along double-stranded RNA for efficient signal transduction. Nature communications 14 (1) (2023)
Kentaro Sakaniwa, Akiko Fujimura, Takuma Shibata, Hideki Shigematsu, Toru Ekimoto, Masaki Yamamoto, Mitsunori Ikeguchi, Kensuke Miyake, Umeharu Ohto, Toshiyuki Shimizu
TLR3 forms a laterally aligned multimeric complex along double-stranded RNA for efficient signal transduction. Nature communications 14 (1) (2023)
Takuma Shibata, Ryota Sato, Masato Taoka, Shin-Ichiroh Saitoh, Mayumi Komine, Kiyoshi Yamaguchi, Susumu Goyama, Yuji Motoi, Jiro Kitaura, Kumi Izawa, Yoshio Yamauchi, Yumiko Tsukamoto, Takeshi Ichinohe, Etsuko Fujita, Ryosuke Hiranuma, Ryutaro Fukui, Yoichi Furukawa, Toshio Kitamura, Toshiyuki Takai, Arinobu Tojo, Mamitaro Ohtsuki, Umeharu Ohto, Toshiyuki Shimizu, Manabu Ozawa, Nobuaki Yoshida, Toshiaki Isobe, Eicke Latz, Kojiro Mukai, Tomohiko Taguchi, Hiroaki Hemmi, Shizuo Akira, Kensuke Miyake
TLR7/8 stress response drives histiocytosis in SLC29A3 disorders. The Journal of experimental medicine 220 (9) (2023)
Kentaro Sakaniwa, Akiko Fujimura, Takuma Shibata, Hideki Shigematsu, Toru Ekimoto, Masaki Yamamoto, Mitsunori Ikeguchi, Kensuke Miyake, Umeharu Ohto, Toshiyuki Shimizu
TLR3 forms a laterally aligned multimeric complex along double-stranded RNA for efficient signal transduction. Nature communications 14 (1) (2023)
Atsuko Deguchi, Miho Watanabe-Takahashi, Taishi Mishima, Tsutomu Omori, Umeharu Ohto, Nobuto Arashiki, Fumio Nakamura, Kiyotaka Nishikawa, Yoshiro Maru
Novel multivalent S100A8 inhibitory peptides attenuate tumor progression and metastasis by inhibiting the TLR4-dependent pathway. Cancer gene therapy (2023)
Jinta Asami, Kanako Terakado Kimura, Yoko Fujita-Fujiharu, Hanako Ishida, Zhikuan Zhang, Yayoi Nomura, Kehong Liu, Tomoko Uemura, Yumi Sato, Masatsugu Ono, Masaki Yamamoto, Takeshi Noda, Hideki Shigematsu, David Drew, So Iwata, Toshiyuki Shimizu, Norimichi Nomura, Umeharu Ohto
Structure of the bile acid transporter and HBV receptor NTCP. Nature 606 (7916) (2022)
Yukie Kamitsukasa, Kenji Nakano, Karin Murakami, Kunio Hirata, Masaki Yamamoto, Toshiyuki Shimizu, Umeharu Ohto
The structure of NLRP9 reveals a unique C-terminal region with putative regulatory function. FEBS letters 596 (7) (2022)
Zhikuan Zhang, Norimichi Nomura, Yukiko Muramoto, Toru Ekimoto, Tomoko Uemura, Kehong Liu, Moeko Yui, Nozomu Kono, Junken Aoki, Mitsunori Ikeguchi, Takeshi Noda, So Iwata, Umeharu Ohto, Toshiyuki Shimizu
Structure of SARS-CoV-2 membrane protein essential for virus assembly. Nature communications 13 (1) (2022)
Hanako Ishida, Jinta Asami, Zhikuan Zhang, Tomohiro Nishizawa, Hideki Shigematsu, Umeharu Ohto, Toshiyuki Shimizu
Cryo-EM structures of Toll-like receptors in complex with UNC93B1. Nature structural & molecular biology 28 (2) (2021)
Yi Yang, Adam Csakai, Shuangshuang Jiang, Christina Smith, Hiromi Tanji, Jian Huang, Torey Jones, Kentaro Sakaniwa, Lindsey Broadwell, Chengrui Shi, Subada Soti, Umeharu Ohto, Yaohui Fang, Shu Shen, Fei Deng, Toshiyuki Shimizu, Hang Yin
Tetrasubstituted imidazoles as incognito Toll-like receptor 8 a(nta)gonists. Nature communications 12 (1) (2021)
Mamiko Masutani, Shunya Sakurai, Toshiyuki Shimizu, Umeharu Ohto
Crystal structure of TEX101, a glycoprotein essential for male fertility, reveals the presence of tandemly arranged Ly6/uPAR domains. FEBS letters 594 (18) (2020)