William E Broderick

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 21

Top Topics

Electron Transfer

Molecular Dynamics

Lymph Node Metastasis

Top Venues

Journal of the American Chemical Society

Angewandte Chemie (International ed. in English)

Proceedings of the National Academy of Sciences of the United States of America

Dalton transactions (Cambridge, England : 2003)

This page only lists publications with an associated author ORCID identifier.

Publications

William G Walls, Anna Lisa Vagstad, Tyler Delridge, Jörn Piel, William E Broderick, Joan B Broderick
Direct Detection of the α-Carbon Radical Intermediate Formed by OspD: Mechanistic Insights into Radical S -Adenosyl-l-methionine Peptide Epimerization. Journal of the American Chemical Society 146 (8) (2024)
Hao Yang, Madeline B Ho, Maike N Blakely, Martín A Mosquera, William E Broderick, Joan B Broderick, Brian M Hoffman
ENDOR Spectroscopy Reveals the "Free" 5'-Deoxyadenosyl Radical in a Radical SAM Enzyme Active Site Actually is Chaperoned by Close Interaction with the Methionine-Bound [4Fe-4S] 2+ Cluster. Journal of the American Chemical Society 146 (6) (2024)
Hao Yang, Madeline B Ho, Maike N Blakely, Martín A Mosquera, William E Broderick, Joan B Broderick, Brian M Hoffman
ENDOR Spectroscopy Reveals the "Free" 5'-Deoxyadenosyl Radical in a Radical SAM Enzyme Active Site Actually is Chaperoned by Close Interaction with the Methionine-Bound [4Fe-4S] 2+ Cluster. Journal of the American Chemical Society 146 (6) (2024)
Hao Yang, Madeline B Ho, Maike N Blakely, Martín A Mosquera, William E Broderick, Joan B Broderick, Brian M Hoffman
ENDOR Spectroscopy Reveals the "Free" 5'-Deoxyadenosyl Radical in a Radical SAM Enzyme Active Site Actually is Chaperoned by Close Interaction with the Methionine-Bound [4Fe-4S] 2+ Cluster. Journal of the American Chemical Society 146 (6) (2024)
William G Walls, Anna Lisa Vagstad, Tyler Delridge, Jörn Piel, William E Broderick, Joan B Broderick
Direct Detection of the α-Carbon Radical Intermediate Formed by OspD: Mechanistic Insights into Radical S -Adenosyl-l-methionine Peptide Epimerization. Journal of the American Chemical Society 146 (8) (2024)
William G Walls, Anna Lisa Vagstad, Tyler Delridge, Jörn Piel, William E Broderick, Joan B Broderick
Direct Detection of the α-Carbon Radical Intermediate Formed by OspD: Mechanistic Insights into Radical S -Adenosyl-l-methionine Peptide Epimerization. Journal of the American Chemical Society 146 (8) (2024)
William G Walls, Anna Lisa Vagstad, Tyler Delridge, Jörn Piel, William E Broderick, Joan B Broderick
Direct Detection of the α-Carbon Radical Intermediate Formed by OspD: Mechanistic Insights into Radical S -Adenosyl-l-methionine Peptide Epimerization. Journal of the American Chemical Society 146 (8) (2024)
Hao Yang, Madeline B Ho, Maike N Blakely, Martín A Mosquera, William E Broderick, Joan B Broderick, Brian M Hoffman
ENDOR Spectroscopy Reveals the "Free" 5'-Deoxyadenosyl Radical in a Radical SAM Enzyme Active Site Actually is Chaperoned by Close Interaction with the Methionine-Bound [4Fe-4S] 2+ Cluster. Journal of the American Chemical Society (2024)
William G Walls, Anna Lisa Vagstad, Tyler Delridge, Jörn Piel, William E Broderick, Joan B Broderick
Direct Detection of the α-Carbon Radical Intermediate Formed by OspD: Mechanistic Insights into Radical S -Adenosyl-l-methionine Peptide Epimerization. Journal of the American Chemical Society (2024)
William G Walls, Anna Lisa Vagstad, Tyler Delridge, Jörn Piel, William E Broderick, Joan B Broderick
Direct Detection of the α-Carbon Radical Intermediate Formed by OspD: Mechanistic Insights into Radical S -Adenosyl-l-methionine Peptide Epimerization. Journal of the American Chemical Society 146 (8) (2024)
Hao Yang, Madeline B Ho, Maike N Blakely, Martín A Mosquera, William E Broderick, Joan B Broderick, Brian M Hoffman
ENDOR Spectroscopy Reveals the "Free" 5'-Deoxyadenosyl Radical in a Radical SAM Enzyme Active Site Actually is Chaperoned by Close Interaction with the Methionine-Bound [4Fe-4S] 2+ Cluster. Journal of the American Chemical Society 146 (6) (2024)
William G Walls, Anna Lisa Vagstad, Tyler Delridge, Jörn Piel, William E Broderick, Joan B Broderick
Direct Detection of the α-Carbon Radical Intermediate Formed by OspD: Mechanistic Insights into Radical S -Adenosyl-l-methionine Peptide Epimerization. Journal of the American Chemical Society 146 (8) (2024)
Richard J Jodts, M Wittkop, Madeline B Ho, William E Broderick, Joan B Broderick, Brian M Hoffman, Martín A Mosquera
Computational Description of Alkylated Iron-Sulfur Organometallic Clusters. Journal of the American Chemical Society (2023)
Batuhan Balci, Roark D O'Neill, Eric M Shepard, Adrien Pagnier, Alexander Marlott, Michael T Mock, William E Broderick, Joan B Broderick
Semisynthetic maturation of [FeFe]-hydrogenase using [Fe 2 (μ-SH) 2 (CN) 2 (CO) 4 ] 2- : key roles for HydF and GTP. Chemical communications (Cambridge, England) (2023)
Maike N Blakely, Hao Yang, William E Broderick, Brian M Hoffman, Joan B Broderick
Pyruvate formate-lyase activating enzyme: The catalytically active 5'-deoxyadenosyl radical caught in the act of H-atom abstraction. Proceedings of the National Academy of Sciences of the United States of America 120 (47) (2023)
Adrien Pagnier, Batuhan Balci, Eric M Shepard, Hao Yang, Douglas M Warui, Stella Impano, Squire J Booker, Brian M Hoffman, William E Broderick, Joan B Broderick
[FeFe]-Hydrogenase: Defined Lysate-Free Maturation Reveals a Key Role for Lipoyl-H-Protein in DTMA Ligand Biosynthesis. Angewandte Chemie (International ed. in English) 61 (22) (2022)
Adrien Pagnier, Batuhan Balci, Eric M Shepard, William E Broderick, Joan B Broderick
[FeFe]-Hydrogenase In Vitro Maturation. Angewandte Chemie (International ed. in English) 61 (49) (2022)
Maike N Blakely, Raymond Sarksian, Hao Yang, Richard J Jodts, Adrien Pagnier, Donald F Smith, Martín A Mosquera, Wilfred A van der Donk, Brian M Hoffman, William E Broderick, Joan B Broderick
Mechanism of Radical S -Adenosyl- l-methionine Adenosylation: Radical Intermediates and the Catalytic Competence of the 5'-Deoxyadenosyl Radical. Journal of the American Chemical Society 144 (11) (2022)
Eric M Shepard, Stella Impano, Benjamin R Duffus, Adrien Pagnier, Kaitlin S Duschene, Jeremiah N Betz, Amanda S Byer, Amanda Galambas, Elizabeth C McDaniel, Hope Watts, Shawn Erin McGlynn, John W Peters, William E Broderick, Joan B Broderick
HydG, the "dangler" iron, and catalytic production of free CO and CN-: implications for [FeFe]-hydrogenase maturation. Dalton transactions (Cambridge, England : 2003) 50 (30) (2021)
Stella Impano, Hao Yang, Richard J Jodts, Adrien Pagnier, Ryan Swimley, Elizabeth C McDaniel, Eric M Shepard, William E Broderick, Joan B Broderick, Brian M Hoffman
Active-Site Controlled, Jahn-Teller Enabled Regioselectivity in Reductive S-C Bond Cleavage of S-Adenosylmethionine in Radical SAM Enzymes. Journal of the American Chemical Society 143 (1) (2020)
Adrien Pagnier, Hao Yang, Richard J Jodts, Christopher D James, Eric M Shepard, Stella Impano, William E Broderick, Brian M Hoffman, Joan B Broderick
Radical SAM Enzyme Spore Photoproduct Lyase: Properties of the Ω Organometallic Intermediate and Identification of Stable Protein Radicals Formed during Substrate-Free Turnover. Journal of the American Chemical Society 142 (43) (2020)