William S Denney (Wiliam S Denney)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 8

Top Venues

Clinical and translational science

Nature metabolism

Journal of veterinary pharmacology and therapeutics

Science translational medicine

Human Predictions

University of Pennsylvania (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Human Predictions

United States

Chief Scientist

Pfizer Research Technology Center

United States

Director :: Clinical Pharmacology

Merck and Co Inc West Point

United States

Senior Research Pharmacokineticist :: Clinical Pharmacokinetics and Pharmacodynamics

Education History

University of Pennsylvania

United States

PHD :: Chemical and Biomolecular Engineering

University of Pennsylvania

United States

MSC :: Chemical and Biomolecular Engineering

Georgia Institute of Technology

United States

BSC :: Chemical Engineering

Publications

Ewa Gatlik, Beata Mehes, Emilie Voltz, Ulrike Sommer, Elaine Tritto, Giulia Lestini, Xiaoxi Liu, Parasar Pal, Maria Velinova, William S Denney, Yunlin Fu, Anthony Opipari, Dennis Dean, Guido Junge
First-in-human safety, tolerability, and pharmacokinetic results of DFV890, an oral low-molecular-weight NLRP3 inhibitor. Clinical and translational science 17 (5) (2024)
Ewa Gatlik, Beata Mehes, Emilie Voltz, Ulrike Sommer, Elaine Tritto, Giulia Lestini, Xiaoxi Liu, Parasar Pal, Maria Velinova, William S Denney, Yunlin Fu, Anthony Opipari, Dennis Dean, Guido Junge
First-in-human safety, tolerability, and pharmacokinetic results of DFV890, an oral low-molecular-weight NLRP3 inhibitor. Clinical and translational science 17 (5) (2024)
Ewa Gatlik, Beata Mehes, Emilie Voltz, Ulrike Sommer, Elaine Tritto, Giulia Lestini, Xiaoxi Liu, Parasar Pal, Maria Velinova, William S Denney, Yunlin Fu, Anthony Opipari, Dennis Dean, Guido Junge
First-in-human safety, tolerability, and pharmacokinetic results of DFV890, an oral low-molecular-weight NLRP3 inhibitor. Clinical and translational science 17 (5) (2024)
Jerry Vockley, Neal Sondheimer, Marja K Puurunen, George A Diaz, Ilona Ginevic, Dorothy K Grange, Cary O Harding, Hope Northrup, John A Phillips, Shawn Searle, Janet A Thomas, Roberto Zori, William S Denney, Sharon L Ernst, Kristina Humphreys, Nicole McWhorter, Caroline B Kurtz, Aoife M Brennan
Efficacy and safety of a synthetic biotic for treatment of phenylketonuria: a phase 2 clinical trial. Nature metabolism (2023)
Marja K Puurunen, Jerry Vockley, Shawn L Searle, Stephanie J Sacharow, John A Phillips, William S Denney, Benjamin D Goodlett, David A Wagner, Larry Blankstein, Mary J Castillo, Mark R Charbonneau, Vincent M Isabella, Vasu V Sethuraman, Richard J Riese, Caroline B Kurtz, Aoife M Brennan
Safety and pharmacodynamics of an engineered E. coli Nissle for the treatment of phenylketonuria: a first-in-human phase 1/2a study. Nature metabolism 3 (8) (2021)
Sarah E Shane, Vernon C Langston, Robert W Wills, William S Denney, Heather K Knych, Robin L Fontenot, Robert E Meyer, Claudio C Natalini
Pharmacokinetics and pharmacodynamics of intravenous continuous rate infusion and repeated intramuscular administration of dexmedetomidine in standing horses. Journal of veterinary pharmacology and therapeutics 44 (4) (2021)
Mark R Charbonneau, William S Denney, Nicholas G Horvath, Pasquale Cantarella, Mary J Castillo, Marja K Puurunen, Aoife M Brennan
Development of a mechanistic model to predict synthetic biotic activity in healthy volunteers and patients with phenylketonuria. Communications biology 4 (1) (2021)
Caroline B Kurtz, Yves A Millet, Marja K Puurunen, Mylène Perreault, Mark R Charbonneau, Vincent M Isabella, Jonathan W Kotula, Eugene Antipov, Yossi Dagon, William S Denney, David A Wagner, Kip A West, Andrew J Degar, Aoife M Brennan, Paul F Miller
An engineered E. coli Nissle improves hyperammonemia and survival in mice and shows dose-dependent exposure in healthy humans. Science translational medicine 11 (475) (2020)

William S Denney.css-eqlu8i{font-size:small;padding-left:4px;} (Wiliam S Denney)

Publication Activity (10 Years)

Top Topics

Top Venues

William S Denney (Wiliam S Denney)