Clinical and translational science

Keyphrases

Publications

2023

Amanda Roberta Revoredo Vicentino, Vanderlei da Silva Fraga-Junior, Matheus Palazzo, Natalia Recardo Amorim Tasmo, Danielle A S Rodrigues, Shana Priscila Coutinho Barroso, Samila Natiane Ferreira, Anna Cristina Neves Borges, Diego Allonso, Marcelo Rosado Fantappié, Julio Scharfstein, Ana Carolina Oliveira, Rosane Vianna-Jorge, André Macedo Vale, Robson Coutinho-Silva, Luiz Eduardo Baggio Savio, Claudio Canetti, Claudia Farias Benjamim
High mobility group box 1, ATP, lipid mediators, and tissue factor are elevated in COVID-19 patients: HMGB1 as a biomarker of worst prognosis. Clinical and translational science (2023)
Justin D Anderson, Brittney H Davis, Gracie Giang, April Jones, Cameron R Lee, Kennedy Parker, Heather Searcy, Kim Benner, Nita A Limdi, Jennifer S Guimbellot
Pharmacogenetic actionability and medication prescribing in people with cystic fibrosis. Clinical and translational science (2023)
Sharon M Rymut, Lindsay M Henderson, Victor Poon, Tracy L Staton, Fang Cai, Siddharth Sukumaran, Horace Rhee, Ryan Owen, Saroja Ramanujan, Kenta Yoshida
A mechanistic PK/PD model to enable dose selection of the potent anti-tryptase antibody (MTPS9579A) in patients with moderate-to-severe asthma. Clinical and translational science (2023)
Junyi Li, David C Turner, Feifei Li, Xi Chen, Michael Z Liao, Chunze Li
Pharmacokinetics of biologics in gastric cancer. Clinical and translational science (2023)
Logan Brooks, Michael Dolton, Jurgen Langenhorst, Kenta Yoshida, Yi Ting Kayla Lien, Vikram Malhi, Chunze Li, Pablo Perez-Moreno, John Bond, Ya-Chi Chen, Jiajie Yu
Concentration QTc analysis of giredestrant: Overcoming QT/heart rate confounding in the presence of drug-induced heart rate changes. Clinical and translational science (2023)
Kazutaka Oda, Tomoyuki Yamada, Kazuaki Matsumoto, Yuki Hanai, Takashi Ueda, Masaru Samura, Akari Shigemi, Hirofumi Jono, Hideyuki Saito, Toshimi Kimura
Model-informed precision dosing of teicoplanin for the rapid achievement of the target area under the concentration-time curve: A simulation study. Clinical and translational science (2023)
Wesley Partridge, Sebastien A Burel, Annie Ferng, Shuting Xia, T Jesse Kwoh, Scott P Henry, Brenda F Baker
Correlations Between Preclinical BJAB Assay Ranking of Antisense Drugs and Clinical Trial Adverse Events. Clinical and translational science (2023)
Ingrid M Pruimboom-Brees, Swati Gupta, Nagendra Chemuturi, Helen S Booler, Erik Nimz, Meg Ferrell Ramos, Antonello Caruso, Katie F Maass, Vladimir Bantseev, Qihong Huang, Mary P Choules, Jesse C Nussbaum, Jitendra Kanodia, Christopher Thompson, Chandrasekar Durairaj
International consortium for innovation and quality: An industry perspective on the nonclinical and early clinical development of intravitreal drugs. Clinical and translational science (2023)
Timothy Chow, Pirouz Shamszad, Christopher Vinnard, Esther Yoon, Julia Belinski, Irene Karpenko, Laurent Perrin, Kristen Auwarter, Michael Storek, Howard Surks, Nancy Wong, Yehuda Z Cohen
First-in-human study with SAR445088: A novel selective classical complement pathway inhibitor. Clinical and translational science (2023)
Oriol Mitjà, Gilmar Reis, David R Boulware, Adam M Spivak, Ammar Sarwar, Christine Johnston, Brandon Webb, Michael D Hill, Davey Smith, Peter Kremsner, Marla Curran, David Carter, Jim Alexander, Marc Corbacho-Monné, Todd C Lee, Katherine Huppler Hullsiek, Emily G McDonald, Rachel Hess, Michael Hughes, Jared M Baeten, Ilan Schwartz, Luanne Metz, Lawrence Richer, Kara W Chew, Eric Daar, David Wohl, Michael Dunne
Hydroxychloroquine for treatment of non-hospitalized adults with COVID-19: A meta-analysis of individual participant data of randomized trials. Clinical and translational science (2023)
Rui Li, Yukang Zhang, Shuai Zheng, Linggang Cheng, Yanfen Zhang, Zhiguang Chen, Wen He, Wei Zhang
Noninvasive assessment of carotid plaque with subharmonic aided pressure estimation from a US contrast agent: A preliminary study. Clinical and translational science (2023)
Xiang Wang, Jingwei Zheng, Hui Yang, Xinxin Yang, Wentao Cai, Xiaodong Chen, Weiteng Zhang, Xian Shen
Prognostic value of the preoperative albumin-bilirubin score among patients with stages I-III gastric cancer undergoing radical resection: A retrospective study. Clinical and translational science (2023)
Viviana Giannuzzi, Lucia Ruggieri, Rosa Conte, Cristina Manfredi, Mariagrazia Felisi, Christine Kubiak, Mihaela Matei, Salma Malik, Jacques Demotes, Adriana Ceci, Donato Bonifazi
PedCRIN tool for the biosamples management in pediatric clinical trials. Clinical and translational science (2023)
Keiko Matsuura, Satoshi Kushio, Hiromitsu Imai, Hideo Kudo, Hirokazu Wakuda, Naoyuki Otani, Masae Kuranari, Ai Sekiguchi, Tetsuji Ohyama, Naoto Uemura
Association between psychomotor function and ALDH2 genotype after consuming barley shochu: A randomized crossover trial. Clinical and translational science (2023)
Matthew P Kosloski, Hong Li, Stanley Wang, Federico Mensa, Jens Kort, Wei Liu
Characterizing Complex and Competing Drug-Drug Interactions Between the Antiviral Regimen of Glecaprevir and Pibrentasvir with Rifampin or Carbamazepine. Clinical and translational science (2023)
Viviana Giannuzzi, Lucia Ruggieri, Rosa Conte, Cristina Manfredi, Mariagrazia Felisi, Christine Kubiak, Mihaela Matei, Salma Malik, Jacques Demotes, Adriana Ceci, Donato Bonifazi
PedCRIN tool for the biosamples management in paediatric clinical trials. Clinical and translational science (2023)
Sriram Subramaniam, Stacy S Shord, Ruby Leong, Kelly Norsworthy, Atiqur Rahman, Brian Booth, Olanrewaju Okusanya
Study design considerations to assess the impact of potential drug-drug interactions in first-in-human studies in oncology drug development. Clinical and translational science (2023)
Aline Barth, Caroline R Perry, Shaila Shabbir, Maciej J Zamek-Gliszczynski, Sebin Thomas, Etienne F Dumont, Darin B Brimhall, Dung Nguyen, Meenakshi Srinivasan, Brandon Swift
Clinical Assessment of Gepotidacin (GSK2140944) as a Victim and Perpetrator of Drug-Drug Interactions via CYP3A Metabolism and Transporters. Clinical and translational science (2023)
Alison Luckey, Emilie Alirol, Sophie Delhomme, John O'Donnell, Esther Bettiol, John Mueller, Seamus O'Brien, Jean-Yves Gillon
Effect of food on the pharmacokinetics of zoliflodacin granules for oral suspension: Phase I open-label randomized cross-over study in healthy subjects. Clinical and translational science (2023)
Robert Hermann, Amin Rostami-Hodjegan, Ping Zhao, Isabelle Ragueneau-Majlessi
Seeing What Is Behind the Smokescreen: A Systematic Review of Methodological Aspects of Smoking Interaction Studies over the Last Three Decades and Implications for Future Clinical Trials. Clinical and translational science (2023)
Xiang Wang, Jingwei Zheng, Hui Yang, Xinxin Yang, Wentao Cai, Xiaodong Chen, Weiteng Zhang, Xian Shen
Prognostic value of the preoperative albumin-bilirubin score among patients with stages I-III gastric cancer undergoing radical resection: A retrospective study. Clinical and translational science (2023)
Ge Liu, Lan Jiang, V Eric Kerchberger, Annette Oeser, Andrea Ihegword, Alyson L Dickson, Laura L Daniel, Christian Shaffer, MacRae F Linton, Nancy Cox, Cecilia P Chung, Wei-Qi Wei, C Michael Stein, QiPing Feng
The relationship between high density lipoprotein cholesterol and sepsis: A clinical and genetic approach. Clinical and translational science (2023)
Veroniek E M Harbers, Lilly G J M Zwerink, Gerard A Rongen, Willemijn M Klein, Carine J M van der Vleuten, Ingrid M P van Rijnsoever, Lynda Gerdsen-Drury, Uta E Flucke, Bas H Verhoeven, Peter C J de Laat, Chantal M A M van der Horst, Leo J Schultze Kool, D Maroeska W M Te Loo
Clinical differences in sirolimus treatment with low target levels between children and adults with vascular malformations - A nationwide trial. Clinical and translational science (2023)
Linda Sprague Martinez, Deborah Chassler, Rebecca Lobb, Dema Hakim, Jennifer Pamphile, Tracy A Battaglia
A discussion among deans on advancing community engaged research. Clinical and translational science (2023)
Simon Ekman, Zsolt Cselényi, Andrea Varrone, Aurelija Jucaite, Heather Martin, Magnus Schou, Peter Johnström, Gianluca Laus, Rolf Lewensohn, Andrew P Brown, Jasper van der Aart, Karthick Vishwanathan, Lars Farde
Brain exposure of osimertinib in patients with EGFRm NSCLC and brain metastases: a PET and MRI study. Clinical and translational science (2023)
Monique A Pond, Deepa Narayanan, Kehui Zhang, Danielle Fau, Jeffrey Summers, Dorn Carranza, Michael Weingarten
CARE program: NCI and FDA interagency collaborations to support oncology small business entrepreneurs. Clinical and translational science (2023)
Robert Hermann, Amin Rostami-Hodjegan, Ping Zhao, Isabelle Ragueneau-Majlessi
Seeing what is behind the smokescreen: A systematic review of methodological aspects of smoking interaction studies over the last three decades and implications for future clinical trials. Clinical and translational science (2023)
Logan Brooks, Michael Dolton, Jurgen Langenhorst, Kenta Yoshida, Yi Ting Kayla Lien, Vikram Malhi, Chunze Li, Pablo Perez-Moreno, John Bond, Ya-Chi Chen, Jiajie Yu
Concentration QTc Analysis of Giredestrant: Overcoming QT/HR Confounding in the Presence of Drug-Induced Heart Rate Changes. Clinical and translational science (2023)
Justin D Anderson, Brittney H Davis, Gracie Giang, April Jones, Cameron R Lee, Kennedy Parker, Heather Searcy, Kim Benner, Nita A Limdi, Jennifer S Guimbellot
Pharmacogenetic actionability and medication prescribing in people with cystic fibrosis. Clinical and translational science (2023)
Ingrid M Pruimboom-Brees, Swati Gupta, Nagendra Chemuturi, Helen S Booler, Erik Nimz, Meg Ferrell Ramos, Antonello Caruso, Katie F Maass, Vladimir Bantseev, Qihong Huang, Mary P Choules, Jesse C Nussbaum, Jitendra Kanodia, Christopher Thompson, Chandrasekar Durairaj
International Consortium for Innovation and Quality: An Industry Perspective on the Non-clinical and Early Clinical Development of Intravitreal Drugs. Clinical and translational science (2023)
Kathleen M Tornatore, Kristopher Attwood, Rocco C Venuto, Brian Murray
Age associations with Tacrolimus and Mycophenolic Acid Pharmacokinetics in Stable Black and White Kidney Transplant Recipients: Implications for Health Inequities. Clinical and translational science (2023)
Michelle Y Martin, Ansley Grimes Stanfill
On the road to achieving work-life balance in academia. Clinical and translational science (2023)
Marino Carnovali, Cristiano Spada, Peter Uebel, Paolo Bocus, Renato Cannizzaro, Flaminia Cavallaro, Bruno Mario Cesana, Paola Cesaro, Guido Costamagna, Dhanai Di Paolo, Angelo Paulo Ferrari, Carsten Hinkel, Sergey Kashin, Arianna Massella, Ekaterina Melnikova, Anna Orsatti, Thierry Ponchon, Alberto Prada, Franco Radaelli, Sandro Sferrazza, Pietro Soru, Pier Alberto Testoni, Gian Eugenio Tontini, Maurizio Vecchi, Giancarla Fiori, null null
Factors influencing the presence of potentially explosive gases during colonoscopy: Results of the SATISFACTION study. Clinical and translational science (2023)
Aline Barth, Caroline R Perry, Shaila Shabbir, Maciej J Zamek-Gliszczynski, Sebin Thomas, Etienne F Dumont, Darin B Brimhall, Dung Nguyen, Meenakshi Srinivasan, Brandon Swift
Clinical assessment of gepotidacin (GSK2140944) as a victim and perpetrator of drug-drug interactions via CYP3A metabolism and transporters. Clinical and translational science (2023)
Hongjie Qian, Chengyin Yu, Huijuan Zhu, Qichen Ding, Yuting Cai, Jiao Jing, Xin Xu, Runcong Guo, Haiyan Zhang, Hong Liu, Xiaoyan Chen, Yun Liu
Safety, tolerability, and pharmacokinetics of fluoropezil (DC20), a novel acetylcholinesterase inhibitor: A phase I study in healthy young and elderly Chinese subjects. Clinical and translational science (2023)
Ge Liu, Lan Jiang, V Eric Kerchberger, Annette Oeser, Andrea Ihegword, Alyson L Dickson, Laura L Daniel, Christian Shaffer, MacRae F Linton, Nancy Cox, Cecilia P Chung, Wei-Qi Wei, C Michael Stein, QiPing Feng
The relationship between high density lipoprotein cholesterol and sepsis: A clinical and genetic approach. Clinical and translational science (2023)

volume 16, number 3, 2023

Ge Liu, Lan Jiang, V Eric Kerchberger, Annette Oeser, Andrea Ihegword, Alyson L Dickson, Laura L Daniel, Christian Shaffer, MacRae F Linton, Nancy Cox, Cecilia P Chung, Wei-Qi Wei, C Michael Stein, QiPing Feng
The relationship between high density lipoprotein cholesterol and sepsis: A clinical and genetic approach. Clinical and translational science 16 (3) (2023)
Rui Li, Yukang Zhang, Shuai Zheng, Linggang Cheng, Yanfen Zhang, Zhiguang Chen, Wen He, Wei Zhang
Noninvasive assessment of carotid plaque with subharmonic aided pressure estimation from a US contrast agent: A preliminary study. Clinical and translational science 16 (3) (2023)
Michael Boyiadzis, Pinkal Desai, Nikki Daskalakis, William Donnellan, Lucille Ferrante, Jenna D Goldberg, Michael R Grunwald, Christina Guttke, Xiang Li, Jose Antonio Perez-Simon, Olga Salamero, Trevor Tucker, Xiaoying Xu, Jay Yang, Naveen Pemmaraju, Juan Manuel Alonso-Domínguez
First-in-human study of JNJ-63709178, a CD123/CD3 targeting antibody, in relapsed/refractory acute myeloid leukemia. Clinical and translational science 16 (3) (2023)
Ge Liu, Lan Jiang, V Eric Kerchberger, Annette Oeser, Andrea Ihegword, Alyson L Dickson, Laura L Daniel, Christian Shaffer, MacRae F Linton, Nancy Cox, Cecilia P Chung, Wei-Qi Wei, C Michael Stein, QiPing Feng
The relationship between high density lipoprotein cholesterol and sepsis: A clinical and genetic approach. Clinical and translational science 16 (3) (2023)
Monique A Pond, Deepa Narayanan, Kehui Zhang, Danielle Fau, Jeffrey Summers, Dorn Carranza, Michael Weingarten
CARE program: NCI and FDA interagency collaborations to support oncology small business entrepreneurs. Clinical and translational science 16 (3) (2023)
Islam R Younis, Brian J Kirby, Andrew N Billin, Deqing Xiao, Qinghua Song, Timothy R Watkins, Ahmed A Othman
Pharmacokinetics, pharmacodynamics, safety and tolerability of cilofexor, a novel nonsteroidal Farnesoid X receptor agonist, in healthy volunteers. Clinical and translational science 16 (3) (2023)
Rui Li, Yukang Zhang, Shuai Zheng, Linggang Cheng, Yanfen Zhang, Zhiguang Chen, Wen He, Wei Zhang
Noninvasive assessment of carotid plaque with subharmonic aided pressure estimation from a US contrast agent: A preliminary study. Clinical and translational science 16 (3) (2023)
Oriol Mitjà, Gilmar Reis, David R Boulware, Adam M Spivak, Ammar Sarwar, Christine Johnston, Brandon Webb, Michael D Hill, Davey Smith, Peter Kremsner, Marla Curran, David Carter, Jim Alexander, Marc Corbacho-Monné, Todd C Lee, Katherine Huppler Hullsiek, Emily G McDonald, Rachel Hess, Michael Hughes, Jared M Baeten, Ilan Schwartz, Luanne Metz, Lawrence Richer, Kara W Chew, Eric Daar, David Wohl, Michael Dunne
Hydroxychloroquine for treatment of non-hospitalized adults with COVID-19: A meta-analysis of individual participant data of randomized trials. Clinical and translational science 16 (3) (2023)
Islam R Younis, Brian J Kirby, Andrew N Billin, Deqing Xiao, Qinghua Song, Timothy R Watkins, Ahmed A Othman
Pharmacokinetics, pharmacodynamics, safety and tolerability of cilofexor, a novel nonsteroidal Farnesoid X receptor agonist, in healthy volunteers. Clinical and translational science 16 (3) (2023)
Oriol Mitjà, Gilmar Reis, David R Boulware, Adam M Spivak, Ammar Sarwar, Christine Johnston, Brandon Webb, Michael D Hill, Davey Smith, Peter Kremsner, Marla Curran, David Carter, Jim Alexander, Marc Corbacho-Monné, Todd C Lee, Katherine Huppler Hullsiek, Emily G McDonald, Rachel Hess, Michael Hughes, Jared M Baeten, Ilan Schwartz, Luanne Metz, Lawrence Richer, Kara W Chew, Eric Daar, David Wohl, Michael Dunne
Hydroxychloroquine for treatment of non-hospitalized adults with COVID-19: A meta-analysis of individual participant data of randomized trials. Clinical and translational science 16 (3) (2023)
Monique A Pond, Deepa Narayanan, Kehui Zhang, Danielle Fau, Jeffrey Summers, Dorn Carranza, Michael Weingarten
CARE program: NCI and FDA interagency collaborations to support oncology small business entrepreneurs. Clinical and translational science 16 (3) (2023)
Michael Boyiadzis, Pinkal Desai, Nikki Daskalakis, William Donnellan, Lucille Ferrante, Jenna D Goldberg, Michael R Grunwald, Christina Guttke, Xiang Li, Jose Antonio Perez-Simon, Olga Salamero, Trevor Tucker, Xiaoying Xu, Jay Yang, Naveen Pemmaraju, Juan Manuel Alonso-Domínguez
First-in-human study of JNJ-63709178, a CD123/CD3 targeting antibody, in relapsed/refractory acute myeloid leukemia. Clinical and translational science 16 (3) (2023)

volume 16, number 6, 2023

Ismael Castaneda, Karen Marder, Sudha Kashyap, Michael Rosenbaum
Clinical research resource support for off-site research coordinators in intensive and specialty care units. Clinical and translational science 16 (6) (2023)

volume 16, number 8, 2023

Richard F Ittenbach
From clinical data management to clinical data science: Time for a new educational model. Clinical and translational science 16 (8) (2023)