Xinyuan Zhu

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 73

Top Topics

Histone Deacetylase

Top Venues

Biomaterials science

ACS applied materials & interfaces

Environmental science & technology

Journal of the American Chemical Society

This page only lists publications with an associated author ORCID identifier.

Publications

Jiwei Cui, Lijun Du, Zhiheng Meng, Jiayin Gao, Anning Tan, Xin Jin, Xinyuan Zhu
Ingenious Structure Engineering to Enhance Piezoelectricity in Poly(vinylidene fluoride) for Biomedical Applications. Biomacromolecules (2024)
Xinmiao Lu, Yunyun Zhu, Xiaohui Deng, Fei Kong, Chuang Xi, Quanyong Luo, Xinyuan Zhu
Development of a Supermolecular Radionuclide-Drug Conjugate System for Integrated Radiotheranostics for Non-small Cell Lung Cancer. Journal of medicinal chemistry 67 (13) (2024)
Xinmiao Lu, Yunyun Zhu, Xiaohui Deng, Fei Kong, Chuang Xi, Quanyong Luo, Xinyuan Zhu
Development of a Supermolecular Radionuclide-Drug Conjugate System for Integrated Radiotheranostics for Non-small Cell Lung Cancer. Journal of medicinal chemistry 67 (13) (2024)
Cheng Huang, Yucen Deng, Rongze Ma, Hucheng Ge, Fuzhong Gong, Jinghui Yang, Xinyuan Zhu, Youfu Wang
A metal-organic cage-derived cascade antioxidant nanozyme to mitigate renal ischemia-reperfusion injury. Nanoscale (2024)
Ziying Li, Kaiyuan Song, Yu Chen, Qijing Huang, Lujia You, Li Yu, Baiyang Chen, Zihang Yuan, Yaqin Xu, Yue Su, Lin-Tai Da, Xinyuan Zhu, Ruijiao Dong
Sequence-encoded bioactive protein-multiblock polymer conjugates via quantitative one-pot iterative living polymerization. Nature communications 15 (1) (2024)
Xinmiao Lu, Yunyun Zhu, Xiaohui Deng, Fei Kong, Chuang Xi, Quanyong Luo, Xinyuan Zhu
Development of a Supermolecular Radionuclide-Drug Conjugate System for Integrated Radiotheranostics for Non-small Cell Lung Cancer. Journal of medicinal chemistry (2024)
Ziying Li, Kaiyuan Song, Yu Chen, Qijing Huang, Lujia You, Li Yu, Baiyang Chen, Zihang Yuan, Yaqin Xu, Yue Su, Lin-Tai Da, Xinyuan Zhu, Ruijiao Dong
Sequence-encoded bioactive protein-multiblock polymer conjugates via quantitative one-pot iterative living polymerization. Nature communications 15 (1) (2024)
Ziying Li, Kaiyuan Song, Yu Chen, Qijing Huang, Lujia You, Li Yu, Baiyang Chen, Zihang Yuan, Yaqin Xu, Yue Su, Lin-Tai Da, Xinyuan Zhu, Ruijiao Dong
Sequence-encoded bioactive protein-multiblock polymer conjugates via quantitative one-pot iterative living polymerization. Nature communications 15 (1) (2024)
Cheng Huang, Yucen Deng, Rongze Ma, Hucheng Ge, Fuzhong Gong, Jinghui Yang, Xinyuan Zhu, Youfu Wang
A metal-organic cage-derived cascade antioxidant nanozyme to mitigate renal ischemia-reperfusion injury. Nanoscale 16 (19) (2024)
Hongfeng Zhao, Yan Zhang, Chaoyue Xie, Jiachen Wang, Tingsheng Zhou, Changhui Zhou, Jinhua Li, Baoxue Zhou, Xinyuan Zhu, Baoxue Zhou
Facile, Controllable, and Ultrathin NiFe-LDH In Situ Grown on a Ni Foam by Ultrasonic Self-Etching for Highly Efficient Urine Conversion. Environmental science & technology 57 (7) (2023)
Li Xu, Hongping Deng, Liang Wu, Dali Wang, Leilei Shi, Qiuhui Qian, Xiangang Huang, Lijuan Zhu, Xihui Gao, Jiapei Yang, Yue Su, Jing Feng, Xinyuan Zhu
Supramolecular Cyclic Dinucleotide Nanoparticles for STING-Mediated Cancer Immunotherapy. ACS nano (2023)
Li Yu, Baiyang Chen, Ziying Li, Qijing Huang, Kaiyuan He, Yue Su, Zeguang Han, Yongfeng Zhou, Xinyuan Zhu, Deyue Yan, Ruijiao Dong
Digital synthetic polymers for information storage. Chemical Society reviews 52 (5) (2023)
Cheng Huang, Jiajia Li, Xinyuan Zhu, Youfu Wang
Chiral metal-organic cages decorated with binaphthalene moieties. Nanoscale (2023)
Xinting Wu, Ning Ren, Gangsheng Tong, Xinyuan Zhu
Surface Chain-Transfer Ring-Opening Metathesis Polymerization. Langmuir : the ACS journal of surfaces and colloids (2023)
Hongfeng Zhao, Yan Zhang, Chaoyue Xie, Jiachen Wang, Tingsheng Zhou, Changhui Zhou, Jinhua Li, Baoxue Zhou, Xinyuan Zhu, Baoxue Zhou
Facile, Controllable, and Ultrathin NiFe-LDH In Situ Grown on a Ni Foam by Ultrasonic Self-Etching for Highly Efficient Urine Conversion. Environmental science & technology 57 (7) (2023)
Hongfeng Zhao, Yan Zhang, Chaoyue Xie, Jiachen Wang, Tingsheng Zhou, Changhui Zhou, Jinhua Li, Baoxue Zhou, Xinyuan Zhu, Baoxue Zhou
Facile, Controllable, and Ultrathin NiFe-LDH In Situ Grown on a Ni Foam by Ultrasonic Self-Etching for Highly Efficient Urine Conversion. Environmental science & technology (2023)
Li Yu, Baiyang Chen, Ziying Li, Qijing Huang, Kaiyuan He, Yue Su, Zeguang Han, Yongfeng Zhou, Xinyuan Zhu, Deyue Yan, Ruijiao Dong
Digital synthetic polymers for information storage. Chemical Society reviews 52 (5) (2023)
Li Yu, Baiyang Chen, Ziying Li, Qijing Huang, Kaiyuan He, Yue Su, Zeguang Han, Yongfeng Zhou, Xinyuan Zhu, Deyue Yan, Ruijiao Dong
Digital synthetic polymers for information storage. Chemical Society reviews (2023)
Wumaier Yasen, Bei Li, Aliya Aini, Ziying Li, Yue Su, Linzhu Zhou, Dongbo Guo, Qiuhui Qian, Dong Chen, Xinyuan Zhu, Ruijiao Dong
Visible Light-Guided Gene Delivery with Nonviral Supramolecular Block Copolymer Vectors. ACS applied materials & interfaces (2023)
Hongfeng Zhao, Yan Zhang, Chaoyue Xie, Jiachen Wang, Tingsheng Zhou, Changhui Zhou, Jinhua Li, Baoxue Zhou, Xinyuan Zhu, Baoxue Zhou
Facile, Controllable, and Ultrathin NiFe-LDH In Situ Grown on a Ni Foam by Ultrasonic Self-Etching for Highly Efficient Urine Conversion. Environmental science & technology 57 (7) (2023)
Dali Wang, Xinyue Zhang, Xinyuan Zhu
Drug-Grafted DNA for Cancer Therapy. The journal of physical chemistry. B (2023)
Jiapei Yang, Chengshuo Shen, Ting Zhu, Qiuhui Qian, Xuebo Diao, Wei Huang, Wumaier Yasen, Yue Su, Xinyuan Zhu, Leilei Shi
An aminopeptidase N-based color-convertible fluorescent nano-probe for cancer diagnosis. Biomaterials science (2023)
Miao Xie, Fujun Wang, Jiapei Yang, Yuanyuan Guo, Fei Ding, Xinmiao Lu, Yangyang Huang, Yimeng Li, Xinyuan Zhu, Chuan Zhang
DNA Zipper Mediated Membrane Fusion for Rapid Exosomal MiRNA Detection. Analytical chemistry 94 (38) (2022)
Yao Wang, Penghui Wang, Linzhu Zhou, Yue Su, Yongfeng Zhou, Xinyuan Zhu, Wei Huang, Deyue Yan
A novel docetaxel derivative exhibiting potent anti-tumor activity and high safety in preclinical animal models. Biomaterials science 10 (17) (2022)
Yuanyuan Guo, Qiushuang Zhang, Qiwen Zhu, Jing Gao, Xinyuan Zhu, Haijun Yu, Yuehua Li, Chuan Zhang
Copackaging photosensitizer and PD-L1 siRNA in a nucleic acid nanogel for synergistic cancer photoimmunotherapy. Science advances 8 (16) (2022)
Hongping Deng, Yan Chen, Li Xu, Xuan Mo, Jingxuan Ju, Chun-Yang Yu, Xinyuan Zhu
A Biomimetic Emitter Inspired from Green Fluorescent Protein. The journal of physical chemistry. B 126 (43) (2022)
Yan Zhang, Xiaoya Huang, Jinhua Li, Baoxue Zhou, Changhui Zhou, Lei Li, Jiachen Wang, Mingce Long, Xinyuan Zhu, Baoxue Zhou
Rapid Conversion of Co 2+ to Co 3+ by Introducing Oxygen Vacancies in Co 3 O 4 Nanowire Anodes for Nitrogen Removal with Highly Efficient H 2 Recovery in Urine Treatment. Environmental science & technology 56 (13) (2022)
Xinlong Liu, Fei Ding, Yuanyuan Guo, Kai Jiang, Yucheng Fu, Lijuan Zhu, Ming Li, Xinyuan Zhu, Chuan Zhang
Complexing the Pre-assembled Brush-like siRNA with Poly(β-amino ester) for Efficient Gene Silencing. ACS applied bio materials 5 (5) (2022)
Lijuan Zhu, Jiapei Yang, Yuan Ma, Xinyuan Zhu, Chuan Zhang
Aptamers Entirely Built from Therapeutic Nucleoside Analogues for Targeted Cancer Therapy. Journal of the American Chemical Society 144 (4) (2022)
Yuan Ma, Quanbing Mou, Peng Yan, Zhenglin Yang, Ying Xiong, Deyue Yan, Chuan Zhang, Xinyuan Zhu, Yi Lu
A highly sensitive and selective fluoride sensor based on a riboswitch-regulated transcription coupled with CRISPR-Cas13a tandem reaction. Chemical science 12 (35) (2021)
Jiapei Yang, Li Xu, Ling Di, Yue Su, Xinyuan Zhu
Journey of Poly(ethylene Glycol) in Living Cells. ACS applied materials & interfaces 13 (34) (2021)
Yu Huang, Feng Qiu, Rongjun Chen, Deyue Yan, Xinyuan Zhu
Fluorescence resonance energy transfer-based drug delivery systems for enhanced photodynamic therapy. Journal of materials chemistry. B 8 (17) (2021)
Ting Zhu, Leilei Shi, Chuan Ma, Li Xu, Jiapei Yang, Guoyu Zhou, Xinyuan Zhu, Lingyue Shen
Fluorinated chitosan-mediated intracellular catalase delivery for enhanced photodynamic therapy of oral cancer. Biomaterials science 9 (3) (2021)
Qiushuang Zhang, Yuanyuan Guo, Lijuan Zhu, Xinlong Liu, Jiapei Yang, Yuehua Li, Xinyuan Zhu, Chuan Zhang
A nucleic acid nanogel dually bears siRNA and CpG motifs for synergistic tumor immunotherapy. Biomaterials science 9 (13) (2021)
Shuo Huang, Yan Wu, Chao Li, Li Xu, Jie Huang, Yu Huang, Weiwei Cheng, Bai Xue, Linlin Zhang, Sheng Liang, Xin Jin, Xinyuan Zhu, Shuqiang Xiong, Yue Su, Hui Wang
Tailoring morphologies of mesoporous polydopamine nanoparticles to deliver high-loading radioiodine for anaplastic thyroid carcinoma imaging and therapy. Nanoscale 13 (35) (2021)
Wumaier Yasen, Ruijiao Dong, Aliya Aini, Xinyuan Zhu
Recent advances in supramolecular block copolymers for biomedical applications. Journal of materials chemistry. B 8 (36) (2021)
Jie Huang, Peng Zhao, Xin Jin, Yiwen Wang, Haotian Yuan, Xinyuan Zhu
Enzymatic biofuel cells based on protein engineering: recent advances and future prospects. Biomaterials science 8 (19) (2021)
Yunfeng Shi, Sung Jun Lim, Liang Ma, Ning Duan, Xin Yan, Xiaole Tang, Wenyan Yang, Shu Yang, Jiaxin Hu, Andrew M Smith, Xinyuan Zhu
Inorganic-Ligand Quantum Dots Meet Inorganic-Ligand Semiconductor Nanoplatelets: A Promising Fusion to Construct All-Inorganic Assembly. Inorganic chemistry 60 (10) (2021)
Leilei Shi, Fang Hu, Yukun Duan, Wenbo Wu, Jinqiao Dong, Xiangjun Meng, Xinyuan Zhu, Jie Liu
Hybrid Nanospheres to Overcome Hypoxia and Intrinsic Oxidative Resistance for Enhanced Photodynamic Therapy. ACS nano 14 (2) (2020)
Jiao Zhang, Yuanyuan Guo, Gaifang Pan, Ping Wang, Yuehua Li, Xinyuan Zhu, Chuan Zhang
Injectable Drug-Conjugated DNA Hydrogel for Local Chemotherapy to Prevent Tumor Recurrence. ACS applied materials & interfaces 12 (19) (2020)
Yanfei Ma, Mutian Hua, Shuwang Wu, Yingjie Du, Xiaowei Pei, Xinyuan Zhu, Feng Zhou, Ximin He
Bioinspired high-power-density strong contractile hydrogel by programmable elastic recoil. Science advances 6 (47) (2020)
Yuanbo Wang, Leilei Shi, Dou Ma, Shidang Xu, Wenbo Wu, Li Xu, Majid Panahandeh-Fard, Xinyuan Zhu, Bo Wang, Jie Liu
Tumor-Activated and Metal-Organic Framework Assisted Self-Assembly of Organic Photosensitizers. ACS nano 14 (10) (2020)
Hongping Deng, Chun-Yang Yu, Deyue Yan, Xinyuan Zhu
Dual-Self-Restricted GFP Chromophore Analogues with Significantly Enhanced Emission. The journal of physical chemistry. B 124 (5) (2020)
Fei Ding, Xiangang Huang, Xihui Gao, Miao Xie, Gaifang Pan, Qifeng Li, Jie Song, Xinyuan Zhu, Chuan Zhang
A non-cationic nucleic acid nanogel for the delivery of the CRISPR/Cas9 gene editing tool. Nanoscale 11 (37) (2019)
Quanbing Mou, Yuan Ma, Fei Ding, Xihui Gao, Deyue Yan, Xinyuan Zhu, Chuan Zhang
Two-in-One Chemogene Assembled from Drug-Integrated Antisense Oligonucleotides To Reverse Chemoresistance. Journal of the American Chemical Society 141 (17) (2019)
Qinghua Guan, Nan Li, Leilei Shi, Chun-Yang Yu, Xihui Gao, Jiapei Yang, Yuanyuan Guo, Peiyong Li, Xinyuan Zhu
Aggregation-Induced Emission Fluorophore-Based Molecular Beacon for Differentiating Tumor and Normal Cells by Detecting the Specific and False-Positive Signals. ACS biomaterials science & engineering 5 (7) (2019)
Jiao Zhang, Yuanyuan Guo, Fei Ding, Gaifang Pan, Xinyuan Zhu, Chuan Zhang
A Camptothecin-Grafted DNA Tetrahedron as a Precise Nanomedicine to Inhibit Tumor Growth. Angewandte Chemie (International ed. in English) 58 (39) (2019)
Qiuhui Qian, Leilei Shi, Xihui Gao, Yuan Ma, Jiapei Yang, Zhihao Zhang, Jiwen Qian, Xinyuan Zhu
A Paclitaxel-Based Mucoadhesive Nanogel with Multivalent Interactions for Cervical Cancer Therapy. Small (Weinheim an der Bergstrasse, Germany) 15 (47) (2019)
Gaifang Pan, Quanbing Mou, Yuan Ma, Fei Ding, Jiao Zhang, Yuanyuan Guo, Xiangang Huang, Qifeng Li, Xinyuan Zhu, Chuan Zhang
pH-Responsive and Gemcitabine-Containing DNA Nanogel To Facilitate the Chemodrug Delivery. ACS applied materials & interfaces 11 (44) (2019)
Qinghua Guan, Leilei Shi, Chunting Li, Xihui Gao, Kai Wang, Xiaofei Liang, Peiyong Li, Xinyuan Zhu
A Fluorescent Cocktail Strategy for Differentiating Tumor, Inflammation, and Normal Cells by Detecting mRNA and H2O2. ACS biomaterials science & engineering 5 (2) (2019)
Huangyong Jiang, Dongbo Guo, Dong Chen, Yan Wu, Xin Jin, Xinyuan Zhu
A new insight into the reversal of multidrug resistance in cancer by nanodrugs. Biomaterials science 7 (8) (2019)
Leilei Shi, Xihui Gao, Wangzhang Yuan, Li Xu, Hongping Deng, Chenwei Wu, Jiapei Yang, Xin Jin, Chuan Zhang, Xinyuan Zhu
Endoplasmic Reticulum-Targeted Fluorescent Nanodot with Large Stokes Shift for Vesicular Transport Monitoring and Long-Term Bioimaging. Small (Weinheim an der Bergstrasse, Germany) 14 (25) (2018)
Leilei Shi, Li Xu, Chenwei Wu, Bai Xue, Xin Jin, Jiapei Yang, Xinyuan Zhu
Celecoxib-Induced Self-Assembly of Smart Albumin-Doxorubicin Conjugate for Enhanced Cancer Therapy. ACS applied materials & interfaces 10 (10) (2018)
Huangyong Jiang, Dong Chen, Dongbo Guo, Nan Wang, Yue Su, Xin Jin, Gangsheng Tong, Xinyuan Zhu
Zwitterionic gold nanorods: low toxicity and high photothermal efficacy for cancer therapy. Biomaterials science 5 (4) (2018)
Yi Hu, Leilei Shi, Yue Su, Chuan Zhang, Xin Jin, Xinyuan Zhu
A fluorescent light-up aggregation-induced emission probe for screening gefitinib-sensitive non-small cell lung carcinoma. Biomaterials science 5 (4) (2018)
Leilei Shi, Qinghua Guan, Xihui Gao, Xin Jin, Li Xu, Jian Shen, Chenwei Wu, Xinyuan Zhu, Chuan Zhang
Reaction-Based Color-Convertible Fluorescent Probe for Ferroptosis Identification. Analytical chemistry 90 (15) (2018)
Guocan Yu, Xinlian Zhao, Jiong Zhou, Zhengwei Mao, Xiaolin Huang, Zhantong Wang, Bin Hua, Yijing Liu, Fuwu Zhang, Zhimei He, Orit Jacobson, Changyou Gao, Weilin Wang, Chun-Yang Yu, Xinyuan Zhu, Feihe Huang, Xiaoyuan Shawn Chen
Supramolecular Polymer-Based Nanomedicine: High Therapeutic Performance and Negligible Long-Term Immunotoxicity. Journal of the American Chemical Society 140 (25) (2018)
Leilei Shi, Li Xu, Qinghua Guan, Xin Jin, Jiapei Yang, Xinyuan Zhu
Light-Trigerred Cellular Epigenetic Molecule Release To Reverse Tumor Multidrug Resistance. Bioconjugate chemistry 29 (4) (2018)
Yongjia Liu, Ruibin Wang, Jingwen Hou, Binbin Sun, Bangshang Zhu, Zhiguang Qiao, Yue Su, Xinyuan Zhu
Paclitaxel/Chitosan Nanosupensions Provide Enhanced Intravesical Bladder Cancer Therapy with Sustained and Prolonged Delivery of Paclitaxel. ACS applied bio materials 1 (6) (2018)
Dong Chen, Yu Huang, Huangyong Jiang, Wumaier Yasen, Dongbo Guo, Yue Su, Bai Xue, Xin Jin, Xinyuan Zhu
Fabrication of Activity-Reporting Glucose Oxidase Nanocapsules with Oxygen-Independent Fluorescence Variation. ACS applied materials & interfaces 10 (31) (2018)
Chuan Ma, Leilei Shi, Yu Huang, Lingyue Shen, Hao Peng, Xinyuan Zhu, Guoyu Zhou
Nanoparticle delivery of Wnt-1 siRNA enhances photodynamic therapy by inhibiting epithelial-mesenchymal transition for oral cancer. Biomaterials science 5 (3) (2018)
Dali Wang, Chun-Yang Yu, Li Xu, Leilei Shi, Gangsheng Tong, Jieli Wu, Hong Liu, Deyue Yan, Xinyuan Zhu
Nucleoside Analogue-Based Supramolecular Nanodrugs Driven by Molecular Recognition for Synergistic Cancer Therapy. Journal of the American Chemical Society 140 (28) (2018)
Li Xu, Jiapei Yang, Yumin Liu, Leilei Shi, Chenwei Wu, Hua Jin, Xin Jin, Yue Su, Xinyuan Zhu
Short-term urea cycle inhibition in rat liver cells induced by polyethylene glycol. Biomaterials science 6 (11) (2018)
Chunting Li, Ruijun Pan, Peiyong Li, Qinghua Guan, Junping Ao, Kai Wang, Li Xu, Xiaofei Liang, Xin Jin, Chuan Zhang, Xinyuan Zhu
Hydrogen Peroxide-Responsive Nanoprobe Assists Circulating Tumor Cell Identification and Colorectal Cancer Diagnosis. Analytical chemistry 89 (11) (2017)
Pei Sun, Nan Wang, Xin Jin, Xinyuan Zhu
"Bottom-Up" Construction of Hyperbranched Poly(prodrug-co-photosensitizer) Amphiphiles Unimolecular Micelles for Chemo-Photodynamic Dual Therapy. ACS applied materials & interfaces 9 (42) (2017)
Rui Chen, Ning Ren, Xin Jin, Xinyuan Zhu
Role Transformation of Poly( N-isopropylacrylamide) Microgels from Stabilizer to Seed in Dispersion Polymerization by Controlling the Water Content in Methanol-Water Mixture. Langmuir : the ACS journal of surfaces and colloids 34 (11) (2017)
Pei Sun, Dong Chen, Hongping Deng, Nan Wang, Ping Huang, Xin Jin, Xinyuan Zhu
"Bottom-up" Construction of Multi-Polyprodrug-Arm Hyperbranched Amphiphiles for Cancer Therapy. Bioconjugate chemistry 28 (5) (2017)
Xiaopei Zhang, Wei Chen, Xinyuan Zhu, Yunfeng Lu
Encapsulating Therapeutic Proteins with Polyzwitterions for Lower Macrophage Nonspecific Uptake and Longer Circulation Time. ACS applied materials & interfaces 9 (9) (2017)
Dali Wang, Bing Liu, Yuan Ma, Chenwei Wu, Quanbing Mou, Hongping Deng, Ruibin Wang, Deyue Yan, Chuan Zhang, Xinyuan Zhu
A Molecular Recognition Approach To Synthesize Nucleoside Analogue Based Multifunctional Nanoparticles for Targeted Cancer Therapy. Journal of the American Chemical Society 139 (40) (2017)
Zhihao Zhang, Leilei Shi, Chenwei Wu, Yue Su, Jiwen Qian, Hongping Deng, Xinyuan Zhu
Construction of a Supramolecular Drug-Drug Delivery System for Non-Small-Cell Lung Cancer Therapy. ACS applied materials & interfaces 9 (35) (2017)
Wumaier Yasen, Ruijiao Dong, Linzhu Zhou, Jieli Wu, Chengxi Cao, Aliya Aini, Xinyuan Zhu
Synthesis of a Cationic Supramolecular Block Copolymer with Covalent and Noncovalent Polymer Blocks for Gene Delivery. ACS applied materials & interfaces 9 (10) (2017)
Nan Wang, Xin Jin, Dongbo Guo, Gangsheng Tong, Xinyuan Zhu
Iron Chelation Nanoparticles with Delayed Saturation as an Effective Therapy for Parkinson Disease. Biomacromolecules 18 (2) (2016)
Leilei Shi, Yi Hu, Ang Lin, Chuan Ma, Chuan Zhang, Yue Su, Linzhu Zhou, Yumei Niu, Xinyuan Zhu
Matrix Metalloproteinase Responsive Nanoparticles for Synergistic Treatment of Colorectal Cancer via Simultaneous Anti-Angiogenesis and Chemotherapy. Bioconjugate chemistry 27 (12) (2016)