Yuk Ming Dennis Lo (Y M Dennis Lo, Ym Dennis Lo, Y M D Lo)

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 28

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

NPJ genomic medicine

Prenatal diagnosis

eLife

The Chinese University of Hong Kong

This page only lists publications with an associated author ORCID identifier.

Affiliation History

The Chinese University of Hong Kong

Hong Kong

Li Ka Shing Professor of Medicine :: Department of Chemical Pathology

Publications

Wai Kei Jacky Lam, Wanxia Gai, Jinyue Bai, Tommy H C Tam, Wai Fung Cheung, Lu Ji, Irene O L Tse, Amy F C Tsang, Maggie Z J Li, Peiyong Jiang, Man Fai Law, Raymond S M Wong, K C Allen Chan, Yuk Ming Dennis Lo
Differential detection of megakaryocytic and erythroid DNA in plasma in hematological disorders. NPJ genomic medicine 9 (1) (2024)
Wai Kei Jacky Lam, Wanxia Gai, Jinyue Bai, Tommy H C Tam, Wai Fung Cheung, Lu Ji, Irene O L Tse, Amy F C Tsang, Maggie Z J Li, Peiyong Jiang, Man Fai Law, Raymond S M Wong, K C Allen Chan, Yuk Ming Dennis Lo
Differential detection of megakaryocytic and erythroid DNA in plasma in hematological disorders. NPJ genomic medicine 9 (1) (2024)
Wai Kei Jacky Lam, Wanxia Gai, Jinyue Bai, Tommy H C Tam, Wai Fung Cheung, Lu Ji, Irene O L Tse, Amy F C Tsang, Maggie Z J Li, Peiyong Jiang, Man Fai Law, Raymond S M Wong, K C Allen Chan, Yuk Ming Dennis Lo
Differential detection of megakaryocytic and erythroid DNA in plasma in hematological disorders. NPJ genomic medicine 9 (1) (2024)
Ze Zhou, Mary-Jane L Ma, Rebecca W Y Chan, W K Jacky Lam, Wenlei Peng, Wanxia Gai, Xi Hu, Spencer C Ding, Lu Ji, Qing Zhou, Peter P H Cheung, Stephanie C Y Yu, Jeremy Y C Teoh, Cheuk-Chun Szeto, John Wong, Vincent W S Wong, Grace L H Wong, Stephen Lam Chan, Edwin P Hui, Brigette B Y Ma, Anthony T C Chan, Rossa W K Chiu, K C Allen Chan, Yuk Ming Dennis Lo, Peiyong Jiang
Fragmentation landscape of cell-free DNA revealed by deconvolutional analysis of end motifs. Proceedings of the National Academy of Sciences of the United States of America 120 (17) (2023)
Austin K Mattox, Christopher B Douville, Yuxuan Wang, Maria Popoli, Janine Ptak, Natalie Sillman, Lisa Dobbyn, Joy Schaefer, Steve Lu, Alexander H Pearlman, Joshua David Cohen, Jeanne Tie, Peter Gibbs, Kamel Lahouel, Chetan Bettegowda, Ralph H Hruban, Cristian Tomasetti, Peiyong Jiang, Allen K C Chan, Yuk Ming Dennis Lo, Nickolas Papadopoulos, Kenneth W Kinzler, Bert Vogelstein
The origin of highly elevated cell-free DNA in healthy individuals and patients with pancreatic, colorectal, lung, or ovarian cancer. Cancer discovery (2023)
Stephanie Cheuk Yin Yu, L Y Lois Choy, Yuk Ming Dennis Lo
'Longing' for the Next Generation of Liquid Biopsy: The Diagnostic Potential of Long Cell-Free DNA in Oncology and Prenatal Testing. Molecular diagnosis & therapy (2023)
Wanxia Gai, Stephanie Cheuk Yin Yu, W T Charlotte Chan, Wenlei Peng, So Ling Lau, Tak Yeung Leung, Peiyong Jiang, K C Allen Chan, Yuk Ming Dennis Lo
Droplet digital PCR is a cost-effective method for analyzing long cell-free DNA in maternal plasma: Application in preeclampsia. Prenatal diagnosis (2023)
Christopher S Williams, W Kimryn Rathmell, John M Carethers, Diane M Harper, Yuk Ming Dennis Lo, Peter J Ratcliffe, Mone Zaidi
A global view of the aspiring physician-scientist. eLife 11 (2022)
Tingting Xie, Guangya Wang, Spencer C Ding, Wing-Shan Lee, Suk Hang Cheng, Rebecca W Y Chan, Ze Zhou, Mary-Jane L Ma, Diana S C Han, Jeremy Y C Teoh, W K Jacky Lam, Peiyong Jiang, Rossa W K Chiu, K C Allen Chan, Yuk Ming Dennis Lo
High-resolution analysis for urinary DNA jagged ends. NPJ genomic medicine 7 (1) (2022)
Qing Zhou, Guannan Kang, Peiyong Jiang, Rong Qiao, W K Jacky Lam, Stephanie C Y Yu, Mary-Jane L Ma, Lu Ji, Suk Hang Cheng, Wanxia Gai, Wenlei Peng, Huimin Shang, Rebecca W Y Chan, Stephen Lam Chan, Grace L H Wong, Linda T Hiraki, Stefano Volpi, Vincent W S Wong, John Wong, Rossa W K Chiu, K C Allen Chan, Yuk Ming Dennis Lo
Epigenetic analysis of cell-free DNA by fragmentomic profiling. Proceedings of the National Academy of Sciences of the United States of America 119 (44) (2022)
Philip Johnson, Qing Zhou, Doan Y Dao, Yuk Ming Dennis Lo
Circulating biomarkers in the diagnosis and management of hepatocellular carcinoma. Nature reviews. Gastroenterology & hepatology 19 (10) (2022)
Stephanie C Y Yu, Peiyong Jiang, Wenlei Peng, Suk Hang Cheng, Y T Tommy Cheung, O Y Olivia Tse, Huimin Shang, Liona Chiu Yee Poon, Tak Y Leung, K C Allen Chan, Rossa W K Chiu, Yuk Ming Dennis Lo
Single-molecule sequencing reveals a large population of long cell-free DNA molecules in maternal plasma. Proceedings of the National Academy of Sciences of the United States of America 118 (50) (2022)
Peiyong Jiang, Yuk Ming Dennis Lo
Enhanced cancer detection from cell-free DNA. Nature biotechnology 40 (4) (2022)
O Y Olivia Tse, Peiyong Jiang, Suk Hang Cheng, Wenlei Peng, Huimin Shang, John Wong, Stephen Lam Chan, Liona C Y Poon, Tak Y Leung, K C Allen Chan, Rossa W K Chiu, Yuk Ming Dennis Lo
Genome-wide detection of cytosine methylation by single molecule real-time sequencing. Proceedings of the National Academy of Sciences of the United States of America 118 (5) (2021)
Yuk Ming Dennis Lo
Noninvasive prenatal testing: Advancing through a virtuous circle of science, technology and clinical applications. Prenatal diagnosis 41 (10) (2021)
Yuk Ming Dennis Lo, Diana S C Han, Peiyong Jiang, Rossa W K Chiu
Epigenetics, fragmentomics, and topology of cell-free DNA in liquid biopsies. Science (New York, N.Y.) 372 (6538) (2021)
Wanxia Gai, Ze Zhou, Sean Agbor-Enoh, Xiaodan Fan, Sheng Lian, Peiyong Jiang, Suk Hang Cheng, John Wong, Stephen L Chan, Moon Kyoo Jang, Yanqin Yang, Raymond Hs Liang, Wai Kong Chan, Edmond Sk Ma, Tak Y Leung, Rossa Wk Chiu, Hannah Valantine, Allen K C Chan, Yuk Ming Dennis Lo
Applications of genetic-epigenetic tissue mapping for plasma DNA in prenatal testing, transplantation and oncology. eLife 10 (2021)
Edwin Pun Hui, Brigette B Y Ma, Wai Kei Jacky Lam, K C Allen Chan, Frankie Mo, Qi-Yong Hemis Ai, Ann D King, Chi Hang Wong, Kenneth C W Wong, Daisy C M Lam, Macy Tong, Darren M C Poon, Leung Li, Thomas K H Lau, Kwan Hung Wong, Yuk Ming Dennis Lo, Anthony T C Chan
Dynamic Changes of Post-Radiotherapy Plasma Epstein-Barr Virus DNA in a Randomized Trial of Adjuvant Chemotherapy Versus Observation in Nasopharyngeal Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (10) (2021)
Rossa W K Chiu, Yuk Ming Dennis Lo
Cell-free fetal DNA coming in all sizes and shapes. Prenatal diagnosis 41 (10) (2021)
Peiyong Jiang, Kun Sun, Wenlei Peng, Suk Hang Cheng, Meng Ni, Philip C Yeung, Macy M S Heung, Tingting Xie, Huimin Shang, Ze Zhou, Jason Ying-Kuen Chan, John Wong, Vincent W S Wong, Liona C Poon, Tak Yeung Leung, W K Jacky Lam, Allen K C Chan, Rossa W K Chiu, Yuk Ming Dennis Lo
Plasma DNA End-Motif Profiling as a Fragmentomic Marker in Cancer, Pregnancy, and Transplantation. Cancer discovery 10 (5) (2020)
Ann D King, J K S Woo, Qi-Yong Hemis Ai, Frankie K F Mo, Tiffany Y So, Wai Kei Jacky Lam, I O L Tse, Alexander C Vlantis, K W N Yip, Edwin Pun Hui, Brigette Buig Yue Ma, Rossa W K Chiu, A T C Chan, Yuk Ming Dennis Lo, Allen K C Chan
Early Detection of Cancer: Evaluation of MR Imaging Grading Systems in Patients with Suspected Nasopharyngeal Carcinoma. AJNR. American journal of neuroradiology 41 (3) (2020)
Yuk Ming Dennis Lo, Wai Kei Jacky Lam
Towards multi-cancer screening using liquid biopsies. Nature reviews. Clinical oncology 17 (9) (2020)
Sarah T K Sin, Peiyong Jiang, Jiaen Deng, Lu Ji, Suk Hang Cheng, Anindya Dutta, Tak Y Leung, K C Allen Chan, Rossa W K Chiu, Yuk Ming Dennis Lo
Identification and characterization of extrachromosomal circular DNA in maternal plasma. Proceedings of the National Academy of Sciences of the United States of America 117 (3) (2020)
Wai Kei Jacky Lam, Peiyong Jiang, K C Allen Chan, Wenlei Peng, Huimin Shang, Macy M S Heung, Suk Hang Cheng, Haiqiang Zhang, O Y Olivia Tse, Radha Raghupathy, Brigette B Y Ma, Edwin P Hui, Anthony T C Chan, John K S Woo, Rossa W K Chiu, Yuk Ming Dennis Lo
Methylation analysis of plasma DNA informs etiologies of Epstein-Barr virus-associated diseases. Nature communications 10 (1) (2019)
Kun Sun, Peiyong Jiang, Ada I C Wong, Yvonne K Y Cheng, Suk Hang Cheng, Haiqiang Zhang, K C Allen Chan, Tak Y Leung, Rossa W K Chiu, Yuk Ming Dennis Lo
Size-tagged preferred ends in maternal plasma DNA shed light on the production mechanism and show utility in noninvasive prenatal testing. Proceedings of the National Academy of Sciences of the United States of America 115 (22) (2018)
W K Jacky Lam, Peiyong Jiang, K C Allen Chan, Suk H Cheng, Haiqiang Zhang, Wenlei Peng, O Y Olivia Tse, Yu K Tong, Wanxia Gai, Benny C Y Zee, Brigette B Y Ma, Edwin P Hui, Anthony T C Chan, John K S Woo, Rossa W K Chiu, Yuk Ming Dennis Lo
Sequencing-based counting and size profiling of plasma Epstein-Barr virus DNA enhance population screening of nasopharyngeal carcinoma. Proceedings of the National Academy of Sciences of the United States of America 115 (22) (2018)
Lee Serpas, Rebecca W Y Chan, Peiyong Jiang, Meng Ni, Kun Sun, Ali Rashidfarrokhi, Chetna Soni, Vanja Sisirak, Wing-Shan Lee, Suk Hang Cheng, Wenlei Peng, K C Allen Chan, Rossa W K Chiu, Boris Reizis, Yuk Ming Dennis Lo
Dnase1l3 deletion causes aberrations in length and end-motif frequencies in plasma DNA. Proceedings of the National Academy of Sciences of the United States of America 116 (2) (2018)
Peiyong Jiang, Kun Sun, Yu K Tong, Suk Hang Cheng, Timothy H T Cheng, Macy M S Heung, John Wong, Vincent W S Wong, Henry L Y Chan, K C Allen Chan, Yuk Ming Dennis Lo, Rossa W K Chiu
Preferred end coordinates and somatic variants as signatures of circulating tumor DNA associated with hepatocellular carcinoma. Proceedings of the National Academy of Sciences of the United States of America 115 (46) (2018)

Yuk Ming Dennis Lo.css-eqlu8i{font-size:small;padding-left:4px;} (Y M Dennis Lo, Ym Dennis Lo, Y M D Lo)

Publication Activity (10 Years)

Top Topics

Top Venues

Yuk Ming Dennis Lo (Y M Dennis Lo, Ym Dennis Lo, Y M D Lo)