Peter J Ratcliffe

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 30

Top Topics

Transcription Factor

Histone Deacetylase

Crystal Structure

Endothelial Cells

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

Life science alliance

Nature communications

Cancer research

This page only lists publications with an associated author ORCID identifier.

Publications

Jingyi Ma, Khatoun Al Moussawi, Hantao Lou, Hok Fung Chan, Yihua Wang, Joseph Chadwick, Chansavath Phetsouphanh, Elizabeth A Slee, Shan Zhong, Thomas M Leissing, Andrew Roth, Xiao Qin, Shuo Chen, Jie Yin, Indrika Ratnayaka, Yang Hu, Pakavarin Louphrasitthiphol, Lewis Taylor, Paulo J G Bettencourt, Mary Muers, David R Greaves, Helen McShane, Robert Goldin, Elizabeth J Soilleux, Mathew L Coleman, Peter J Ratcliffe, Xin Lu
Deficiency of factor-inhibiting HIF creates a tumor-promoting immune microenvironment. Proceedings of the National Academy of Sciences of the United States of America 121 (10) (2024)
Samvid Kurlekar, Joana Darc Carola Correia Lima, Ran Li, Olivia Lombardi, Norma Masson, Ayslan B Barros, Virginia Pontecorvi, David R Mole, Christopher W Pugh, Peter J Ratcliffe, Peter J Ratcliffe
Oncogenic Cell Tagging and Single-Cell Transcriptomics Reveal Cell Type-Specific and Time-Resolved Responses to Vhl Inactivation in the Kidney. Cancer research 84 (11) (2024)
Jingyi Ma, Khatoun Al Moussawi, Hantao Lou, Hok Fung Chan, Yihua Wang, Joseph Chadwick, Chansavath Phetsouphanh, Elizabeth A Slee, Shan Zhong, Thomas M Leissing, Andrew Roth, Xiao Qin, Shuo Chen, Jie Yin, Indrika Ratnayaka, Yang Hu, Pakavarin Louphrasitthiphol, Lewis Taylor, Paulo J G Bettencourt, Mary Muers, David R Greaves, Helen McShane, Robert Goldin, Elizabeth J Soilleux, Mathew L Coleman, Peter J Ratcliffe, Xin Lu
Deficiency of factor-inhibiting HIF creates a tumor-promoting immune microenvironment. Proceedings of the National Academy of Sciences of the United States of America 121 (10) (2024)
Jingyi Ma, Khatoun Al Moussawi, Hantao Lou, Hok Fung Chan, Yihua Wang, Joseph Chadwick, Chansavath Phetsouphanh, Elizabeth A Slee, Shan Zhong, Thomas M Leissing, Andrew Roth, Xiao Qin, Shuo Chen, Jie Yin, Indrika Ratnayaka, Yang Hu, Pakavarin Louphrasitthiphol, Lewis Taylor, Paulo J G Bettencourt, Mary Muers, David R Greaves, Helen McShane, Robert Goldin, Elizabeth J Soilleux, Mathew L Coleman, Peter J Ratcliffe, Xin Lu
Deficiency of factor-inhibiting HIF creates a tumor-promoting immune microenvironment. Proceedings of the National Academy of Sciences of the United States of America 121 (10) (2024)
Samvid Kurlekar, Joana Darc Carola Correia Lima, Ran Li, Olivia Lombardi, Norma Masson, Ayslan B Barros, Virginia Pontecorvi, David R Mole, Christopher W Pugh, Peter J Ratcliffe, Peter J Ratcliffe
Oncogenic Cell Tagging and Single-Cell Transcriptomics Reveal Cell Type-Specific and Time-Resolved Responses to Vhl Inactivation in the Kidney. Cancer research 84 (11) (2024)
Samvid Kurlekar, Joana Darc Carola Correia Lima, Ran Li, Olivia Lombardi, Norma Masson, Ayslan B Barros, Virginia Pontecorvi, David R Mole, Christopher W Pugh, Peter J Ratcliffe, Peter J Ratcliffe
Oncogenic Cell Tagging and Single-Cell Transcriptomics Reveal Cell Type-Specific and Time-Resolved Responses to Vhl Inactivation in the Kidney. Cancer research 84 (11) (2024)
Samvid Kurlekar, Joana Darc Carola Correia Lima, Ran Li, Olivia Lombardi, Norma Masson, Ayslan B Barros, Virginia Pontecorvi, David R Mole, Christopher W Pugh, Peter J Ratcliffe, Peter J Ratcliffe
Oncogenic cell tagging and single-cell transcriptomics reveal cell type-specific and time-resolved responses to Vhl inactivation in the kidney. Cancer research (2024)
Jingyi Ma, Khatoun Al Moussawi, Hantao Lou, Hok Fung Chan, Yihua Wang, Joseph Chadwick, Chansavath Phetsouphanh, Elizabeth A Slee, Shan Zhong, Thomas M Leissing, Andrew Roth, Xiao Qin, Shuo Chen, Jie Yin, Indrika Ratnayaka, Yang Hu, Pakavarin Louphrasitthiphol, Lewis Taylor, Paulo J G Bettencourt, Mary Muers, David R Greaves, Helen McShane, Robert Goldin, Elizabeth J Soilleux, Mathew L Coleman, Peter J Ratcliffe, Xin Lu
Deficiency of factor-inhibiting HIF creates a tumor-promoting immune microenvironment. Proceedings of the National Academy of Sciences of the United States of America 121 (10) (2024)
Karen C Heathcote, Thomas P Keeley, Matti Myllykoski, Malin Lundekvam, Nina McTiernan, Salma Akter, Norma Masson, Peter J Ratcliffe, Thomas Arnesen, Emily Flashman
N-terminal cysteine acetylation and oxidation patterns may define protein stability. Nature communications 15 (1) (2024)
Jingyi Ma, Khatoun Al Moussawi, Hantao Lou, Hok Fung Chan, Yihua Wang, Joseph Chadwick, Chansavath Phetsouphanh, Elizabeth A Slee, Shan Zhong, Thomas M Leissing, Andrew Roth, Xiao Qin, Shuo Chen, Jie Yin, Indrika Ratnayaka, Yang Hu, Pakavarin Louphrasitthiphol, Lewis Taylor, Paulo J G Bettencourt, Mary Muers, David R Greaves, Helen McShane, Robert Goldin, Elizabeth J Soilleux, Mathew L Coleman, Peter J Ratcliffe, Xin Lu
Deficiency of factor-inhibiting HIF creates a tumor-promoting immune microenvironment. Proceedings of the National Academy of Sciences of the United States of America 121 (10) (2024)
Karen C Heathcote, Thomas P Keeley, Matti Myllykoski, Malin Lundekvam, Nina McTiernan, Salma Akter, Norma Masson, Peter J Ratcliffe, Thomas Arnesen, Emily Flashman
N-terminal cysteine acetylation and oxidation patterns may define protein stability. Nature communications 15 (1) (2024)
Karen C Heathcote, Thomas P Keeley, Matti Myllykoski, Malin Lundekvam, Nina McTiernan, Salma Akter, Norma Masson, Peter J Ratcliffe, Thomas Arnesen, Emily Flashman
N-terminal cysteine acetylation and oxidation patterns may define protein stability. Nature communications 15 (1) (2024)
Véronique N Lafleur, Silvia Halim, Hani Choudhry, Peter J Ratcliffe, David R Mole
Multi-level interaction between HIF and AHR transcriptional pathways in kidney carcinoma. Life science alliance 6 (4) (2023)
Véronique N Lafleur, Silvia Halim, Hani Choudhry, Peter J Ratcliffe, David R Mole
Multi-level interaction between HIF and AHR transcriptional pathways in kidney carcinoma. Life science alliance 6 (4) (2023)
Véronique N Lafleur, Silvia Halim, Hani Choudhry, Peter J Ratcliffe, David R Mole
Multi-level interaction between HIF and AHR transcriptional pathways in kidney carcinoma. Life science alliance 6 (4) (2023)
Véronique N Lafleur, Silvia Halim, Hani Choudhry, Peter J Ratcliffe, David R Mole
Multi-level interaction between HIF and AHR transcriptional pathways in kidney carcinoma. Life science alliance 6 (4) (2023)
Véronique N Lafleur, Silvia Halim, Hani Choudhry, Peter J Ratcliffe, David R Mole
Multi-level interaction between HIF and AHR transcriptional pathways in kidney carcinoma. Life science alliance 6 (4) (2023)
Christopher S Williams, W Kimryn Rathmell, John M Carethers, Diane M Harper, Yuk Ming Dennis Lo, Peter J Ratcliffe, Mone Zaidi
A global view of the aspiring physician-scientist. eLife 11 (2022)
Yoichiro Sugimoto, Peter J Ratcliffe
Isoform-resolved mRNA profiling of ribosome load defines interplay of HIF and mTOR dysregulation in kidney cancer. Nature structural & molecular biology 29 (9) (2022)
Matthew E Cockman, Yoichiro Sugimoto, Hamish B Pegg, Norma Masson, Eidarus Salah, Anthony Tumber, Helen R Flynn, Joanna M Kirkpatrick, Christopher J Schofield, Peter J Ratcliffe
Widespread hydroxylation of unstructured lysine-rich protein domains by JMJD6. Proceedings of the National Academy of Sciences of the United States of America 119 (32) (2022)
Tammie Bishop, Peter J Ratcliffe
Genetic basis of oxygen sensing in the carotid body: HIF2α and an isoform switch in cytochrome c oxidase subunit 4. Science signaling 13 (615) (2020)
Norma Masson, Thomas P Keeley, Beatrice Giuntoli, Mark D White, Mikel Lavilla Puerta, Pierdomenico Perata, Richard J Hopkinson, Emily Flashman, Francesco Licausi, Peter J Ratcliffe
Conserved N-terminal cysteine dioxygenases transduce responses to hypoxia in animals and plants. Science (New York, N.Y.) 365 (6448) (2020)
Matthew E Cockman, Kerstin Lippl, Ya-Min Tian, Hamish B Pegg, William D Figg, Martine I Abboud, Raphael Heilig, Roman Fischer, Johanna Myllyharju, Christopher J Schofield, Peter J Ratcliffe
Lack of activity of recombinant HIF prolyl hydroxylases (PHDs) on reported non-HIF substrates. eLife 8 (2019)
Johannes Schödel, Peter J Ratcliffe
Mechanisms of hypoxia signalling: new implications for nephrology. Nature reviews. Nephrology 15 (10) (2019)
Virginia Schmid, Veronique N Lafleur, Olivia Lombardi, Ran Li, Rafik Salama, Leandro Colli, Hani Choudhry, Stephen Chanock, Peter J Ratcliffe, David R Mole
Co-incidence of RCC-susceptibility polymorphisms with HIF cis-acting sequences supports a pathway tuning model of cancer. Scientific reports 9 (1) (2019)
Yihua Wang, Shan Zhong, Christopher J Schofield, Peter J Ratcliffe, Xin Lu
Nuclear entry and export of FIH are mediated by HIF1α and exportin1, respectively. Journal of cell science 131 (22) (2018)
James A Smythies, Min Sun, Norma Masson, Rafik Salama, Peter D Simpson, Elizabeth Murray, Viviana Neumann, Matthew E Cockman, Hani Choudhry, Peter J Ratcliffe, David R Mole
Inherent DNA-binding specificities of the HIF-1α and HIF-2α transcription factors in chromatin. EMBO reports 20 (1) (2018)
Steffen Grampp, Virginia Schmid, Rafik Salama, Victoria Lauer, Franziska Kranz, James L Platt, James Smythies, Hani Choudhry, Margarete Goppelt-Struebe, Peter J Ratcliffe, David R Mole, Johannes Schödel
Multiple renal cancer susceptibility polymorphisms modulate the HIF pathway. PLoS genetics 13 (7) (2017)
Tzu-Lan Yeh, Thomas M Leissing, Martine I Abboud, Cyrille C Thinnes, Onur Atasoylu, James P Holt-Martyn, Dong Zhang, Anthony Tumber, Kerstin Lippl, Christopher T Lohans, Ivanhoe K H Leung, Helen Morcrette, Ian J Clifton, Timothy D W Claridge, Akane Kawamura, Emily Flashman, Xin Lu, Peter J Ratcliffe, Rasheduzzaman Chowdhury, Christopher W Pugh, Christopher J Schofield
Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials. Chemical science 8 (11) (2017)
Steffen Grampp, James L Platt, Victoria Lauer, Rafik Salama, Franziska Kranz, Viviana K Neumann, Sven Wach, Christine Stöhr, Arndt Hartmann, Kai-Uwe Eckardt, Peter J Ratcliffe, David R Mole, Johannes Schödel
Genetic variation at the 8q24.21 renal cancer susceptibility locus affects HIF binding to a MYC enhancer. Nature communications 7 (2016)