Youfu Luo

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 39

Top Topics

Reactive Oxygen Species

Quality Control

Methicillin Resistant Staphylococcus Aureus

Top Venues

Journal of medicinal chemistry

Medicinal research reviews

BioMed research international

Molecular diversity

This page only lists publications with an associated author ORCID identifier.

Publications

Xinrong Xiang, Zhengyi Dai, Baozhu Luo, Ninglin Zhao, Song Liu, Jing Sui, Jiasheng Huang, Yuanzheng Zhou, Jinlong Gu, Jiangnan Zhang, Tao Yang, Rui Bao, Youfu Luo
Rational Design of a Novel Class of Human ClpP Agonists through a Ring-Opening Strategy with Enhanced Antileukemia Activity. Journal of medicinal chemistry 67 (8) (2024)
Yunhan Jiang, Xiaoqiu Xu, Dongmei Fan, Pingxian Liu, Meng Zhou, Mengdi Cheng, Jiasheng Huang, Youfu Luo, Yingqiang Guo, Tao Yang
Advancing Tumor-Targeted Chemo-Immunotherapy: Development of the CAR-M-derived Exosome-Drug Conjugate. Journal of medicinal chemistry (2024)
Laiying Zhang, Jiaxing Yang, Xin Xu, Jiangnan Zhang, Zhiqiang Qiu, Yuan Ju, Baozhu Luo, Yan Liu, Xupeng Gou, Jing Sui, Baoyi Chen, Yanmei Wang, Tao Tao, Lei He, Tao Yang, Youfu Luo
Discovery and Optimization of Novel Sa FabI Inhibitors as Specific Therapeutic Agents for MRSA Infection. Journal of medicinal chemistry 67 (12) (2024)
Zongkai Huang, Xupeng Gou, Xudong Hang, Ting Shi, Jiaxing Yang, Yan Liu, Xinlian He, Jin Li, Keao Quan, Hongkai Bi, Youfu Luo
Design, Synthesis, and Biological Evaluation of 5-(5-Iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-2,4-diamine (AF-353) Derivatives as Novel DHFR Inhibitors against Staphylococcus aureus . Journal of medicinal chemistry 67 (6) (2024)
Zongkai Huang, Xupeng Gou, Xudong Hang, Ting Shi, Jiaxing Yang, Yan Liu, Xinlian He, Jin Li, Keao Quan, Hongkai Bi, Youfu Luo
Design, Synthesis, and Biological Evaluation of 5-(5-Iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-2,4-diamine (AF-353) Derivatives as Novel DHFR Inhibitors against Staphylococcus aureus . Journal of medicinal chemistry 67 (6) (2024)
Zongkai Huang, Xupeng Gou, Xudong Hang, Ting Shi, Jiaxing Yang, Yan Liu, Xinlian He, Jin Li, Keao Quan, Hongkai Bi, Youfu Luo
Design, Synthesis, and Biological Evaluation of 5-(5-Iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-2,4-diamine (AF-353) Derivatives as Novel DHFR Inhibitors against Staphylococcus aureus . Journal of medicinal chemistry (2024)
Xinrong Xiang, Zhengyi Dai, Baozhu Luo, Ninglin Zhao, Song Liu, Jing Sui, Jiasheng Huang, Yuanzheng Zhou, Jinlong Gu, Jiangnan Zhang, Tao Yang, Rui Bao, Youfu Luo
Rational Design of a Novel Class of Human ClpP Agonists through a Ring-Opening Strategy with Enhanced Antileukemia Activity. Journal of medicinal chemistry (2024)
Song Liu, Jing Sui, Baozhu Luo, Jiangnan Zhang, Xinrong Xiang, Tao Yang, Youfu Luo, Jie Liu
Discovery of 5-(Piperidin-4-yl)-1,2,4-oxadiazole Derivatives as a New Class of Human Caseinolytic Protease P Agonists for the Treatment of Hepatocellular Carcinoma. Journal of medicinal chemistry 67 (13) (2024)
Laiying Zhang, Jiaxing Yang, Xin Xu, Jiangnan Zhang, Zhiqiang Qiu, Yuan Ju, Baozhu Luo, Yan Liu, Xupeng Gou, Jing Sui, Baoyi Chen, Yanmei Wang, Tao Tao, Lei He, Tao Yang, Youfu Luo
Discovery and Optimization of Novel Sa FabI Inhibitors as Specific Therapeutic Agents for MRSA Infection. Journal of medicinal chemistry 67 (12) (2024)
Song Liu, Jing Sui, Baozhu Luo, Jiangnan Zhang, Xinrong Xiang, Tao Yang, Youfu Luo, Jie Liu
Discovery of 5-(Piperidin-4-yl)-1,2,4-oxadiazole Derivatives as a New Class of Human Caseinolytic Protease P Agonists for the Treatment of Hepatocellular Carcinoma. Journal of medicinal chemistry 67 (13) (2024)
Jiangnan Zhang, Zhiqiang Qiu, Song Liu, Jiasheng Huang, Baozhu Luo, Jing Sui, Zhengyi Dai, Xinrong Xiang, Tao Yang, Youfu Luo
Discovery of a Novel Series of Homo sapiens Caseinolytic Protease P Agonists for Colorectal Adenocarcinoma Treatment via ATF3-Dependent Integrated Stress Response. Journal of medicinal chemistry 67 (4) (2024)
Song Liu, Jing Sui, Baozhu Luo, Jiangnan Zhang, Xinrong Xiang, Tao Yang, Youfu Luo, Jie Liu
Discovery of 5-(Piperidin-4-yl)-1,2,4-oxadiazole Derivatives as a New Class of Human Caseinolytic Protease P Agonists for the Treatment of Hepatocellular Carcinoma. Journal of medicinal chemistry (2024)
Yunhan Jiang, Xiaoqiu Xu, Dongmei Fan, Pingxian Liu, Meng Zhou, Mengdi Cheng, Jiasheng Huang, Youfu Luo, Yingqiang Guo, Tao Yang
Advancing Tumor-Targeted Chemo-Immunotherapy: Development of the CAR-M-derived Exosome-Drug Conjugate. Journal of medicinal chemistry 67 (16) (2024)
Jiangnan Zhang, Zhiqiang Qiu, Song Liu, Jiasheng Huang, Baozhu Luo, Jing Sui, Zhengyi Dai, Xinrong Xiang, Tao Yang, Youfu Luo
Discovery of a Novel Series of Homo sapiens Caseinolytic Protease P Agonists for Colorectal Adenocarcinoma Treatment via ATF3-Dependent Integrated Stress Response. Journal of medicinal chemistry (2024)
Yunhan Jiang, Xiaoqiu Xu, Dongmei Fan, Pingxian Liu, Meng Zhou, Mengdi Cheng, Jiasheng Huang, Youfu Luo, Yingqiang Guo, Tao Yang
Advancing Tumor-Targeted Chemo-Immunotherapy: Development of the CAR-M-derived Exosome-Drug Conjugate. Journal of medicinal chemistry 67 (16) (2024)
Jiangnan Zhang, Zhiqiang Qiu, Song Liu, Jiasheng Huang, Baozhu Luo, Jing Sui, Zhengyi Dai, Xinrong Xiang, Tao Yang, Youfu Luo
Discovery of a Novel Series of Homo sapiens Caseinolytic Protease P Agonists for Colorectal Adenocarcinoma Treatment via ATF3-Dependent Integrated Stress Response. Journal of medicinal chemistry 67 (4) (2024)
Laiying Zhang, Jiaxing Yang, Xin Xu, Jiangnan Zhang, Zhiqiang Qiu, Yuan Ju, Baozhu Luo, Yan Liu, Xupeng Gou, Jing Sui, Baoyi Chen, Yanmei Wang, Tao Tao, Lei He, Tao Yang, Youfu Luo
Discovery and Optimization of Novel Sa FabI Inhibitors as Specific Therapeutic Agents for MRSA Infection. Journal of medicinal chemistry (2024)
Chungen Li, Xirong Tian, Zongkai Huang, Xupeng Gou, Buhari Yusuf, Cong Li, Yamin Gao, Song Liu, Yanmei Wang, Tao Yang, Zhiyong Liu, Qingxiang Sun, Tian-Yu Zhang, Youfu Luo
Structure-Activity Relationship of Novel Pyrimidine Derivatives with Potent Inhibitory Activities against Mycobacterium tuberculosis . Journal of medicinal chemistry 66 (4) (2023)
Xia Zhou, Kun Gou, Jing Xu, Lunan Jian, Yuan Luo, Chungen Li, Xinqi Guan, Jiahao Qiu, Jiao Zou, Yu Zhang, Xi Zhong, Ting Zeng, Yue Zhou, Yuzhou Xiao, Xinyu Yang, Weijie Chen, Ping Gao, Chunqi Liu, Yang Zhou, Lei Tao, Xingchen Liu, Xiao-Bo Cen, Qiang Chen, Qingxiang Sun, Youfu Luo, Yinglan Zhao
Discovery and Optimization of Novel h DHODH Inhibitors for the Treatment of Inflammatory Bowel Disease. Journal of medicinal chemistry (2023)
Yang Yang, Ninglin Zhao, Xin Xu, Yuanzheng Zhou, Baozhu Luo, Jiangnan Zhang, Jing Sui, Jiasheng Huang, Zhiqiang Qiu, Xuelian Zhang, Ju-Mei Zeng, Lang Bai, Rui Bao, Youfu Luo
Discovery and Mechanistic Study of Novel Mycobacterium tuberculosis ClpP1P2 Inhibitors. Journal of medicinal chemistry (2023)
Chungen Li, Xirong Tian, Zongkai Huang, Xupeng Gou, Buhari Yusuf, Cong Li, Yamin Gao, Song Liu, Yanmei Wang, Tao Yang, Zhiyong Liu, Qingxiang Sun, Tian-Yu Zhang, Youfu Luo
Structure-Activity Relationship of Novel Pyrimidine Derivatives with Potent Inhibitory Activities against Mycobacterium tuberculosis . Journal of medicinal chemistry (2023)
Chungen Li, Xirong Tian, Zongkai Huang, Xupeng Gou, Buhari Yusuf, Cong Li, Yamin Gao, Song Liu, Yanmei Wang, Tao Yang, Zhiyong Liu, Qingxiang Sun, Tian-Yu Zhang, Youfu Luo
Structure-Activity Relationship of Novel Pyrimidine Derivatives with Potent Inhibitory Activities against Mycobacterium tuberculosis . Journal of medicinal chemistry 66 (4) (2023)
Pingxian Liu, Yunhan Jiang, Ling Jiao, Youfu Luo, Xiaodong Wang, Tao Yang
Strategies for the Discovery of Oxazolidinone Antibacterial Agents: Development and Future Perspectives. Journal of medicinal chemistry (2023)
Chungen Li, Xirong Tian, Zongkai Huang, Xupeng Gou, Buhari Yusuf, Cong Li, Yamin Gao, Song Liu, Yanmei Wang, Tao Yang, Zhiyong Liu, Qingxiang Sun, Tian-Yu Zhang, Youfu Luo
Structure-Activity Relationship of Novel Pyrimidine Derivatives with Potent Inhibitory Activities against Mycobacterium tuberculosis . Journal of medicinal chemistry 66 (4) (2023)
Jiangnan Zhang, Wenliang Qiao, Youfu Luo
Mitochondrial quality control proteases and their modulation for cancer therapy. Medicinal research reviews (2022)
Cong Li, Song Liu, Baoyu Dong, Chungen Li, Lunan Jian, Juan He, Ju-Mei Zeng, Qiao Zhou, Da Jia, Youfu Luo, Qingxiang Sun
Discovery and Mechanistic Study of Mycobacterium tuberculosis PafA Inhibitors. Journal of medicinal chemistry 65 (16) (2022)
Jiasheng Huang, Jiangnan Zhang, Baozhu Luo, Wenliang Qiao, Zhiqiang Qiu, Rao Song, Zhengyi Dai, Jing Sui, Xin Xu, Shihua Ruan, Chengwei Li, Youfu Luo, Tao Yang
Discovery of a Novel Series of Imipridone Compounds as Homo sapiens Caseinolytic Protease P Agonists with Potent Antitumor Activities In Vitro and In Vivo. Journal of medicinal chemistry 65 (11) (2022)
Xinyi Kuang, Tao Yang, Chenzi Zhang, Xian Peng, Yuan Ju, Chungen Li, Xuedong Zhou, Youfu Luo, Xin Xu
Corrigendum to "Repurposing Napabucasin as an Antimicrobial Agent against Oral Streptococcal Biofilms". BioMed research international 2021 (2021)
Yuqin Lei, Qi An, Xiao-Fei Shen, Min Sui, Chungen Li, Da Jia, Youfu Luo, Qingxiang Sun
Structure-Guided Design of the First Noncovalent Small-Molecule Inhibitor of CRM1. Journal of medicinal chemistry 64 (10) (2021)
Chungen Li, Xiaowei Yang, Yuan Luo, Huan Liu, Xi Zhong, Xia Zhou, Ting Zeng, Lei Tao, Yue Zhou, Kun Gou, Xinyu Yang, Xiaocong Liu, Qiang Chen, Yinglan Zhao, Youfu Luo
Design, Synthesis, and Biological Evaluation of a Novel Series of Teriflunomide Derivatives as Potent Human Dihydroorotate Dehydrogenase Inhibitors for Malignancy Treatment. Journal of medicinal chemistry 64 (24) (2021)
Rao Song, Wenliang Qiao, Jun He, Jiasheng Huang, Youfu Luo, Tao Yang
Proteases and Their Modulators in Cancer Therapy: Challenges and Opportunities. Journal of medicinal chemistry 64 (6) (2021)
Laiying Zhang, Jun He, Lang Bai, Shihua Ruan, Tao Yang, Youfu Luo
Ribosome-targeting antibacterial agents: Advances, challenges, and opportunities. Medicinal research reviews 41 (4) (2021)
Song Liu, Wenliang Qiao, Qingxiang Sun, Youfu Luo
Chromosome Region Maintenance 1 (XPO1/CRM1) as an Anticancer Target and Discovery of Its Inhibitor. Journal of medicinal chemistry 64 (21) (2021)
Yuan Ju, Lihui He, Yuanzheng Zhou, Tao Yang, Ke Sun, Rao Song, Yang Yang, Chengwei Li, Zitai Sang, Rui Bao, Youfu Luo
Discovery of Novel Peptidomimetic Boronate ClpP Inhibitors with Noncanonical Enzyme Mechanism as Potent Virulence Blockers in Vitro and in Vivo. Journal of medicinal chemistry 63 (6) (2020)
Zeping Zuo, Xiaocong Liu, Xinying Qian, Ting Zeng, Na Sang, Huan Liu, Yue Zhou, Lei Tao, Xia Zhou, Na Su, Yamei Yu, Qiang Chen, Youfu Luo, Yinglan Zhao
Bifunctional Naphtho[2,3-d][1,2,3]triazole-4,9-dione Compounds Exhibit Antitumor Effects In Vitro and In Vivo by Inhibiting Dihydroorotate Dehydrogenase and Inducing Reactive Oxygen Species Production. Journal of medicinal chemistry 63 (14) (2020)
Zeping Zuo, Xiaocong Liu, Xinying Qian, Ting Zeng, Na Sang, Huan Liu, Yue Zhou, Lei Tao, Xia Zhou, Na Su, Yamei Yu, Qiang Chen, Youfu Luo, Yinglan Zhao
Correction to "Bifunctional Naphtho[2,3-d][1,2,3]triazole-4,9-dione Compounds Exhibit Antitumor Effects In Vitro and In Vivo by Inhibiting Dihydroorotate Dehydrogenase and Inducing Reactive Oxygen Species Production". Journal of medicinal chemistry 63 (18) (2020)
Xinyi Kuang, Tao Yang, Chenzi Zhang, Xian Peng, Yuan Ju, Chungen Li, Xuedong Zhou, Youfu Luo, Xin Xu
Repurposing Napabucasin as an Antimicrobial Agent against Oral Streptococcal Biofilms. BioMed research international 2020 (2020)
Yang Yang, Yuanzheng Zhou, Lei Tao, Tao Yang, Yinglan Zhao, Youfu Luo
Structure-activity relationship study of DEL-22379: ERK dimerization inhibitors with increased safety. Molecular diversity 25 (2) (2020)
Chungen Li, Yunxiang Tang, Zitai Sang, Yang Yang, Yamin Gao, Tao Yang, Cuiting Fang, Tianyu Zhang, Youfu Luo
Discovery of napabucasin derivatives for the treatment of tuberculosis. MedChemComm 10 (9) (2019)