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Ype Elgersma

ORCID

Publication Activity (10 Years)

Years Active: 2018-2023
Publications (10 Years): 27

Top Venues

International journal of molecular sciences

Molecular autism

Human mutation

eNeuro

Erasmus MC

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Erasmus MC

Netherlands

Professor Molecular Neuroscience :: Neuroscience

Publications

Frédéric Ebstein, Sébastien Küry, Victoria Most, Cory Scott Rosenfelt, Marie-Pier Scott-Boyer, Geeske M van Woerden, Thomas Besnard, Jonas Johannes Papendorf, Maja Studencka-Turski, Tianyun Wang, Tzung-Chien Hsieh, Richard Golnik, Dustin Baldridge, Cara Forster, Charlotte de Konink, Selina M W Teurlings, Virginie Vignard, Richard H van Jaarsveld, Lesley Ades, Benjamin Cogné, Cyril Mignot, Wallid Deb, Marjolijn C J Jongmans, F Sessions Cole, Marie-José H van den Boogaard, Jennifer A Wambach, Daniel J Wegner, Sandra Yang, Vickie Hannig, Jennifer Ann Brault, Neda Zadeh, Bruce Bennetts, Boris Keren, Anne-Claire Gélineau, Zöe Powis, Meghan C Towne, Kristine Bachman, Andrea Seeley, Anita E Beck, Jennifer Morrison, Rachel Westman, Kelly Averill, Theresa Brunet, Judith Haasters, Melissa T Carter, Matthew Osmond, Patricia G Wheeler, Francesca Forzano, Shehla Mohammed, Yannis Trakadis, Andrea Accogli, Rachel Harrison, Yiran Guo, Hakon H Hakonarson, Sophie Rondeau, Geneviève Baujat, Giulia Barcia, René Günther Feichtinger, Johannes Adalbert Mayr, Martin Preisel, Frederic Laumonnier, Tilmann Kallinich, Alexej Knaus, Bertrand Isidor, Peter M Krawitz, Uwe Völker, Elke Hammer, Arnaud Droit, Evan E Eichler, Ype Elgersma, Peter W Hildebrand, Francois V Bolduc, Elke Krüger, Stéphane Bézieau
PSMC3 proteasome subunit variants are associated with neurodevelopmental delay and type I interferon production. Science translational medicine 15 (698) (2023)
Madiha Amin Malik, Muhammad Arif Nadeem Saqib, Edwin Mientjes, Anushree Acharya, Muhammad Rizwan Alam, Ilse Wallaard, Isabelle Schrauwen, Michael J Bamshad, Regie Lyn P Santos-Cortez, Ype Elgersma, Regie Lyn P Santos-Cortez, Muhammad Ansar
A loss of function variant in AGPAT3 underlies intellectual disability and retinitis pigmentosa (IDRP) syndrome. European journal of human genetics : EJHG (2023)
Karen G C B Bindels-de Heus, Doesjka A Hagenaar, Ilonka Dekker, Danielle C M van der Kaay, Gerthe F Kerkhof, null Encore Expertise Center For As, Ype Elgersma, Marie-Claire Y de Wit, Sabine E Mous, Henriette A Moll
Hyperphagia, Growth, and Puberty in Children with Angelman Syndrome. Journal of clinical medicine 12 (18) (2023)
Eva M G Viho, A Mattijs Punt, Ben Distel, Rene Houtman, Jan Kroon, Ype Elgersma, Onno C Meijer
The Hippocampal Response to Acute Corticosterone Elevation Is Altered in a Mouse Model for Angelman Syndrome. International journal of molecular sciences 24 (1) (2022)
Nikhil J Pandya, Sonja Meier, Stefka Tyanova, Marco Terrigno, Congwei Wang, A Mattijs Punt, E J Mientjes, Audrey Vautheny, Ben Distel, Thomas Kremer, Ype Elgersma, Ravi Jagasia
A cross-species spatiotemporal proteomic analysis identifies UBE3A-dependent signaling pathways and targets. Molecular psychiatry 27 (5) (2022)
F Isabella Zampeta, Ben Distel, Ype Elgersma, Rik Iping
From first report to clinical trials: a bibliometric overview and visualization of the development of Angelman syndrome research. Human genetics 141 (12) (2022)
Eva M G Viho, A Mattijs Punt, Ben Distel, Rene Houtman, Jan Kroon, Ype Elgersma, Onno C Meijer
The Hippocampal Response to Acute Corticosterone Elevation Is Altered in a Mouse Model for Angelman Syndrome. International journal of molecular sciences 24 (1) (2022)
Eva M G Viho, A Mattijs Punt, Ben Distel, Rene Houtman, Jan Kroon, Ype Elgersma, Onno C Meijer
The Hippocampal Response to Acute Corticosterone Elevation Is Altered in a Mouse Model for Angelman Syndrome. International journal of molecular sciences 24 (1) (2022)
Stijn N V Bossuyt, A Mattijs Punt, Ilona J de Graaf, Janny van den Burg, Mark G Williams, Helen Heussler, Ype Elgersma, Ben Distel
Loss of nuclear UBE3A activity is the predominant cause of Angelman syndrome in individuals carrying UBE3A missense mutations. Human molecular genetics 30 (6) (2022)
Lucas Wahl, A Mattijs Punt, Tara Arbab, Ingo Willuhn, Ype Elgersma, Aleksandra Badura
A Novel Automated Approach for Improving Standardization of the Marble Burying Test Enables Quantification of Burying Bouts and Activity Characteristics. eNeuro 9 (2) (2022)
Geeske M van Woerden, Melanie Bos, Charlotte de Konink, Ben Distel, Rossella Avagliano Trezza, Natasha E Shur, Kristin Barañano, Sonal Mahida, Anna Chassevent, Allison Schreiber, Angelika L Erwin, Karen W Gripp, Fatima Rehman, Saskia Brulleman, Róisín McCormack, Gwynna de Geus, Louisa Kalsner, Arthur Sorlin, Ange-Line Bruel, David A Koolen, Melissa K Gabriel, Mari Rossi, David R Fitzpatrick, Andrew O M Wilkie, Eduardo Calpena, David Johnson, Alice Brooks, Marjon van Slegtenhorst, Julie Fleischer, Daniel Groepper, Kristin Lindstrom, A Micheil Innes, Allison Goodwin, Jennifer Humberson, Amanda Noyes, Katherine G Langley, Aida Telegrafi, Amy Blevins, Jessica Hoffman, Maria J Guillen Sacoto, Jane Juusola, Kristin G Monaghan, Sumit Punj, Marleen Simon, Rolph Pfundt, Ype Elgersma, Tjitske Kleefstra
TAOK1 is associated with neurodevelopmental disorder and essential for neuronal maturation and cortical development. Human mutation 42 (4) (2021)
Ype Elgersma, Monica Sonzogni
UBE3A reinstatement as a disease-modifying therapy for Angelman syndrome. Developmental medicine and child neurology 63 (7) (2021)
María B Birkisdóttir, Dick Jaarsma, Renata M C Brandt, Sander Barnhoorn, Nicole van Vliet, Sandra Imholz, Conny T van Oostrom, Bhawani Nagarajah, Eliana Portilla-Fernández, Anton J M Roks, Ype Elgersma, Harry van Steeg, José A Ferreira, Jeroen L A Pennings, Jan H J Hoeijmakers, Wilbert P Vermeij, Martijn E T Dollé
Unlike dietary restriction, rapamycin fails to extend lifespan and reduce transcription stress in progeroid DNA repair-deficient mice. Aging cell 20 (2) (2021)
Rossella Avagliano Trezza, A Mattijs Punt, Edwin Mientjes, Marlene van den Berg, F Isabella Zampeta, Ilona J de Graaf, Yana van der Weegen, Jeroen A A Demmers, Ype Elgersma, Ben Distel
Mono-ubiquitination of Rabphilin 3A by UBE3A serves a non-degradative function. Scientific reports 11 (1) (2021)
Martina Proietti Onori, Linda M C Koene, Carmen B Schäfer, Mark Nellist, Marcel de Brito van Velze, Zhenyu Gao, Ype Elgersma, Geeske M van Woerden
RHEB/mTOR hyperactivity causes cortical malformations and epileptic seizures through increased axonal connectivity. PLoS biology 19 (5) (2021)
Myrthe J Ottenhoff, Lianne C Krab, Ype Elgersma
Considerations for Clinical Therapeutic Development of Statins for Neurodevelopmental Disorders. eNeuro 7 (2) (2020)
Myrthe J Ottenhoff, André B Rietman, Sabine E Mous, Ellen Plasschaert, Daniela Gawehns, Hilde Brems, Rianne Oostenbrink, null null, Rick van Minkelen, Mark Nellist, Elizabeth Schorry, Eric Legius, Henriette A Moll, Ype Elgersma
Examination of the genetic factors underlying the cognitive variability associated with neurofibromatosis type 1. Genetics in medicine : official journal of the American College of Medical Genetics 22 (5) (2020)
Monica Sonzogni, Peipei Zhai, Edwin J Mientjes, Geeske M van Woerden, Ype Elgersma
Assessing the requirements of prenatal UBE3A expression for rescue of behavioral phenotypes in a mouse model for Angelman syndrome. Molecular autism 11 (1) (2020)
Monica Sonzogni, Johanna Hakonen, Mireia Bernabé Kleijn, Sara Silva-Santos, Matthew C Judson, Benjamin D Philpot, Geeske M van Woerden, Ype Elgersma
Delayed loss of UBE3A reduces the expression of Angelman syndrome-associated phenotypes. Molecular autism 10 (2019)
Linda M C Koene, Saskia E van Grondelle, Martina Proietti Onori, Ilse Wallaard, Nathalie H R M Kooijman, Annabel van Oort, Jadwiga Schreiber, Ype Elgersma
Effects of antiepileptic drugs in a new TSC/mTOR-dependent epilepsy mouse model. Annals of clinical and translational neurology 6 (7) (2019)
Martijn J Kool, Martina Proietti Onori, Nils Z Borgesius, Jolet E van de Bree, Minetta Elgersma-Hooisma, Enzo Nio, Karel Bezstarosti, Gabriëlle H S Buitendijk, Mehrnoush Aghadavoud Jolfaei, Jeroen A A Demmers, Ype Elgersma, Geeske M van Woerden
CAMK2-Dependent Signaling in Neurons Is Essential for Survival. The Journal of neuroscience : the official journal of the Society for Neuroscience 39 (28) (2019)
Iris E Overwater, André B Rietman, Sabine E Mous, Karen G C B Bindels-de Heus, Dimitris Rizopoulos, Leontine W Ten Hoopen, Thijs van der Vaart, Floor E Jansen, Ype Elgersma, Henriette A Moll, Marie-Claire Y de Wit, null null
A randomized controlled trial with everolimus for IQ and autism in tuberous sclerosis complex. Neurology 93 (2) (2019)
Rossella Avagliano Trezza, Monica Sonzogni, Stijn N V Bossuyt, F Isabella Zampeta, A Mattijs Punt, Marlene van den Berg, Diana C Rotaru, Linda M C Koene, Shashini T Munshi, Jeffrey Stedehouder, Johan M Kros, Mark G Williams, Helen Heussler, Femke M S de Vrij, Edwin J Mientjes, Geeske M van Woerden, Steven A Kushner, Ben Distel, Ype Elgersma
Loss of nuclear UBE3A causes electrophysiological and behavioral deficits in mice and is associated with Angelman syndrome. Nature neuroscience 22 (8) (2019)
Monica Sonzogni, Ilse Wallaard, Sara Silva Santos, Jenina Kingma, Dorine du Mee, Geeske M van Woerden, Ype Elgersma
A behavioral test battery for mouse models of Angelman syndrome: a powerful tool for testing drugs and novel Ube3a mutants. Molecular autism 9 (2018)
Martina Proietti Onori, Balwina Koopal, David B Everman, Jessica D Worthington, Julie R Jones, Melissa A Ploeg, Edwin Mientjes, Bregje W van Bon, Tjitske Kleefstra, Howard Schulman, Steven A Kushner, Sébastien Küry, Ype Elgersma, Geeske M van Woerden
The intellectual disability-associated CAMK2G p.Arg292Pro mutation acts as a pathogenic gain-of-function. Human mutation 39 (12) (2018)
Diana C Rotaru, Geeske M van Woerden, Ilse Wallaard, Ype Elgersma
Adult Ube3a Gene Reinstatement Restores the Electrophysiological Deficits of Prefrontal Cortex Layer 5 Neurons in a Mouse Model of Angelman Syndrome. The Journal of neuroscience : the official journal of the Society for Neuroscience 38 (37) (2018)
Femke M de Vrij, Christian G Bouwkamp, Nilhan Gunhanlar, Guy Shpak, Bas Lendemeijer, Maarouf Baghdadi, Shreekara Gopalakrishna, Mehrnaz Ghazvini, Tracy M Li, Marialuisa Quadri, Simone Olgiati, Guido J Breedveld, Michiel Coesmans, Edwin Mientjes, Ton de Wit, Frans W Verheijen, H Berna Beverloo, Dan Cohen, Rob M Kok, P Roberto Bakker, Aviva Nijburg, Annet T Spijker, P M Judith Haffmans, Erik Hoencamp, Veerle Bergink, null null, Jacob A Vorstman, Timothy Wu, Loes M Olde Loohuis, Najaf Amin, Carolyn D Langen, Albert Hofman, Witte J Hoogendijk, Cornelia M van Duijn, Mohammad Arfan Ikram, Meike W Vernooij, Henning Tiemeier, André G Uitterlinden, Ype Elgersma, Ben Distel, Joost Gribnau, Tonya White, Vincenzo Bonifati, Steven A Kushner
Candidate CSPG4 mutations and induced pluripotent stem cell modeling implicate oligodendrocyte progenitor cell dysfunction in familial schizophrenia. Molecular psychiatry 24 (5) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

Ype Elgersma