Zhen Yan

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 42

Top Venues

Nature communications

Molecular psychiatry

Translational psychiatry

The Journal of physiology

University at Buffalo - The State University of New York

University of Tennessee Health Science Center College of Medicine Memphis Department of Anatomy and Neurobiology (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University at Buffalo - The State University of New York May 01 2000

United States

Professor

The Rockefeller University Dec 06 1997 - Apr 30 2000

United States

Postdoctoral Associate :: Lab of Molecular & Cellular Neuroscience

Education History

University of Tennessee Health Science Center College of Medicine Memphis Department of Anatomy and Neurobiology Aug 01 1994 - Dec 05 1997

United States

PHD

Publications

Luis Gustavo Hernandez Carballo, Pei Li, Rachel Senek, Zhen Yan
Systemic histone deacetylase inhibition ameliorates the aberrant responses to acute stress in socially isolated male mice. The Journal of physiology 602 (9) (2024)
Luis Gustavo Hernandez Carballo, Pei Li, Rachel Senek, Zhen Yan
Systemic histone deacetylase inhibition ameliorates the aberrant responses to acute stress in socially isolated male mice. The Journal of physiology 602 (9) (2024)
Luis Gustavo Hernandez Carballo, Pei Li, Rachel Senek, Zhen Yan
Systemic histone deacetylase inhibition ameliorates the aberrant responses to acute stress in socially isolated male mice. The Journal of physiology (2024)
Luis Gustavo Hernandez Carballo, Pei Li, Rachel Senek, Zhen Yan
Systemic histone deacetylase inhibition ameliorates the aberrant responses to acute stress in socially isolated male mice. The Journal of physiology 602 (9) (2024)
Maximiliano Rapanelli, Wei Wang, Edward Hurley, Maria Laura Feltri, Christopher Pittenger, Luciana Romina Frick, Zhen Yan
Cholinergic neurons in the basal forebrain are involved in behavioral abnormalities associated with Cul3 deficiency: Role of prefrontal cortex projections in cognitive deficits. Translational psychiatry 13 (1) (2023)
Jamal B Williams, Qing Cao, Wei Wang, Young-Ho Lee, Luye Qin, Ping Zhong, Yong Ren, Kaijie Ma, Zhen Yan
Inhibition of histone methyltransferase Smyd3 rescues NMDAR and cognitive deficits in a tauopathy mouse model. Nature communications 14 (1) (2023)
Jamal B Williams, Qing Cao, Wei Wang, Young-Ho Lee, Luye Qin, Ping Zhong, Yong Ren, Kaijie Ma, Zhen Yan
Inhibition of histone methyltransferase Smyd3 rescues NMDAR and cognitive deficits in a tauopathy mouse model. Nature communications 14 (1) (2023)
Maximiliano Rapanelli, Wei Wang, Edward Hurley, Maria Laura Feltri, Christopher Pittenger, Luciana Romina Frick, Zhen Yan
Cholinergic neurons in the basal forebrain are involved in behavioral abnormalities associated with Cul3 deficiency: Role of prefrontal cortex projections in cognitive deficits. Translational psychiatry 13 (1) (2023)
Jamal B Williams, Qing Cao, Wei Wang, Young-Ho Lee, Luye Qin, Ping Zhong, Yong Ren, Kaijie Ma, Zhen Yan
Inhibition of histone methyltransferase Smyd3 rescues NMDAR and cognitive deficits in a tauopathy mouse model. Nature communications 14 (1) (2023)
Maximiliano Rapanelli, Wei Wang, Edward Hurley, Maria Laura Feltri, Christopher Pittenger, Luciana Romina Frick, Zhen Yan
Cholinergic neurons in the basal forebrain are involved in behavioral abnormalities associated with Cul3 deficiency: Role of prefrontal cortex projections in cognitive deficits. Translational psychiatry 13 (1) (2023)
Maximiliano Rapanelli, Wei Wang, Edward Hurley, Maria Laura Feltri, Christopher Pittenger, Luciana Romina Frick, Zhen Yan
Cholinergic neurons in the basal forebrain are involved in behavioral abnormalities associated with Cul3 deficiency: Role of prefrontal cortex projections in cognitive deficits. Translational psychiatry 13 (1) (2023)
Jamal B Williams, Qing Cao, Wei Wang, Young-Ho Lee, Luye Qin, Ping Zhong, Yong Ren, Kaijie Ma, Zhen Yan
Inhibition of histone methyltransferase Smyd3 rescues NMDAR and cognitive deficits in a tauopathy mouse model. Nature communications 14 (1) (2023)
Jamal B Williams, Qing Cao, Wei Wang, Young-Ho Lee, Luye Qin, Ping Zhong, Yong Ren, Kaijie Ma, Zhen Yan
Inhibition of histone methyltransferase Smyd3 rescues NMDAR and cognitive deficits in a tauopathy mouse model. Nature communications 14 (1) (2023)
Maximiliano Rapanelli, Wei Wang, Edward Hurley, Maria Laura Feltri, Christopher Pittenger, Luciana Romina Frick, Zhen Yan
Cholinergic neurons in the basal forebrain are involved in behavioral abnormalities associated with Cul3 deficiency: Role of prefrontal cortex projections in cognitive deficits. Translational psychiatry 13 (1) (2023)
Jamal B Williams, Qing Cao, Wei Wang, Young-Ho Lee, Luye Qin, Ping Zhong, Yong Ren, Kaijie Ma, Zhen Yan
Inhibition of histone methyltransferase Smyd3 rescues NMDAR and cognitive deficits in a tauopathy mouse model. Nature communications 14 (1) (2023)
Maximiliano Rapanelli, Wei Wang, Edward Hurley, Maria Laura Feltri, Christopher Pittenger, Luciana Romina Frick, Zhen Yan
Cholinergic neurons in the basal forebrain are involved in behavioral abnormalities associated with Cul3 deficiency: Role of prefrontal cortex projections in cognitive deficits. Translational psychiatry 13 (1) (2023)
Jamal B Williams, Qing Cao, Wei Wang, Young-Ho Lee, Luye Qin, Ping Zhong, Yong Ren, Kaijie Ma, Zhen Yan
Inhibition of histone methyltransferase Smyd3 rescues NMDAR and cognitive deficits in a tauopathy mouse model. Nature communications 14 (1) (2023)
Hong Li, Houbo Jiang, Hanqin Li, Li Li, Zhen Yan, Jian Feng
Generation of human A9 dopaminergic pacemakers from induced pluripotent stem cells. Molecular psychiatry (2022)
Wei Wang, Tao Tan, Qing Cao, Freddy Zhang, Benjamin Rein, Wei-Ming Duan, Zhen Yan
Histone Deacetylase Inhibition Restores Behavioral and Synaptic Function in a Mouse Model of 16p11.2 Deletion. The international journal of neuropsychopharmacology 25 (10) (2022)
Maximiliano Rapanelli, Jamal B Williams, Kaijie Ma, Fengwei Yang, Ping Zhong, Rajvi Patel, Manasa Kumar, Luye Qin, Benjamin A Rein, Zi-Jun Wang, Bibi Kassim, Behnam Javidfar, Lizette Couto, Schahram Akbarian, Zhen Yan
Targeting histone demethylase LSD1 for treatment of deficits in autism mouse models. Molecular psychiatry 27 (8) (2022)
Megan Conrow-Graham, Jamal B Williams, Jennifer Martin, Ping Zhong, Qing Cao, Benjamin Rein, Zhen Yan
A convergent mechanism of high risk factors ADNP and POGZ in neurodevelopmental disorders. Brain : a journal of neurology 145 (9) (2022)
Zi-Jun Wang, Treefa Shwani, Junting Liu, Ping Zhong, Fengwei Yang, Kelcie Schatz, Freddy Zhang, Arnd Pralle, Zhen Yan
Molecular and cellular mechanisms for differential effects of chronic social isolation stress in males and females. Molecular psychiatry 27 (7) (2022)
Zi-Jun Wang, Benjamin A Rein, Ping Zhong, Jamal Williams, Qing Cao, Fengwei Yang, Freddy Zhang, Kaijie Ma, Zhen Yan
Autism risk gene KMT5B deficiency in prefrontal cortex induces synaptic dysfunction and social deficits via alterations of DNA repair and gene transcription. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 46 (9) (2021)
Wei Wang, Qing Cao, Tao Tan, Fengwei Yang, Jamal B Williams, Zhen Yan
Epigenetic treatment of behavioral and physiological deficits in a tauopathy mouse model. Aging cell 20 (10) (2021)
Jamal B Williams, Qing Cao, Zhen Yan
Transcriptomic analysis of human brains with Alzheimer's disease reveals the altered expression of synaptic genes linked to cognitive deficits. Brain communications 3 (3) (2021)
James P Catlin, Leandro N Marziali, Benjamin Rein, Zhen Yan, M Laura Feltri, Christine E Schaner Tooley
Age-related neurodegeneration and cognitive impairments of NRMT1 knockout mice are preceded by misregulation of RB and abnormal neural stem cell development. Cell death & disease 12 (11) (2021)
Luye Qin, Kaijie Ma, Zhen Yan
Rescue of histone hypoacetylation and social deficits by ketogenic diet in a Shank3 mouse model of autism. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology (2021)
Zhen Yan, Benjamin A Rein
Mechanisms of synaptic transmission dysregulation in the prefrontal cortex: pathophysiological implications. Molecular psychiatry (2021)
Freddy Zhang, Benjamin A Rein, Ping Zhong, Treefa Shwani, Megan Conrow-Graham, Zi-Jun Wang, Zhen Yan
Synergistic inhibition of histone modifiers produces therapeutic effects in adult Shank3-deficient mice. Translational psychiatry 11 (1) (2021)
Luye Qin, Jamal B Williams, Tao Tan, Tiaotiao Liu, Qing Cao, Kaijie Ma, Zhen Yan
Deficiency of autism risk factor ASH1L in prefrontal cortex induces epigenetic aberrations and seizures. Nature communications 12 (1) (2021)
Gerard Sanacora, Zhen Yan, Maurizio Popoli
The stressed synapse 2.0: pathophysiological mechanisms in stress-related neuropsychiatric disorders. Nature reviews. Neuroscience (2021)
Benjamin A Rein, Tao Tan, Fengwei Yang, Wei Wang, Jamal Williams, Freddy Zhang, Alea Mills, Zhen Yan
Reversal of synaptic and behavioral deficits in a 16p11.2 duplication mouse model via restoration of the GABA synapse regulator Npas4. Molecular psychiatry 26 (6) (2020)
Qing Cao, Wei Wang, Jamal B Williams, Fengwei Yang, Zi-Jun Wang, Zhen Yan
Targeting histone K4 trimethylation for treatment of cognitive and synaptic deficits in mouse models of Alzheimer's disease. Science advances 6 (50) (2020)
Ashley E Lepack, Craig T Werner, Andrew F Stewart, Sasha L Fulton, Ping Zhong, Lorna A Farrelly, Alexander C W Smith, Aarthi Ramakrishnan, Yang Lyu, Ryan M Bastle, Jennifer A Martin, Swarup Mitra, Richard M O'Connor, Zi-Jun Wang, Henrik Molina, Gustavo Turecki, Li Shen, Zhen Yan, Erin S Calipari, David M Dietz, Paul J Kenny, Ian Maze
Dopaminylation of histone H3 in ventral tegmental area regulates cocaine seeking. Science (New York, N.Y.) 368 (6487) (2020)
Benjamin Rein, Kaijie Ma, Zhen Yan
A standardized social preference protocol for measuring social deficits in mouse models of autism. Nature protocols 15 (10) (2020)
Kaijie Ma, Luye Qin, Emmanuel Matas, Lara J Duffney, Aiyi Liu, Zhen Yan
Histone deacetylase inhibitor MS-275 restores social and synaptic function in a Shank3-deficient mouse model of autism. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 43 (8) (2019)
Maximiliano Rapanelli, Tao Tan, Wei Wang, Xue Wang, Zi-Jun Wang, Ping Zhong, Luciana Frick, Luye Qin, Kaijie Ma, Jun Qu, Zhen Yan
Behavioral, circuitry, and molecular aberrations by region-specific deficiency of the high-risk autism gene Cul3. Molecular psychiatry 26 (5) (2019)
Junghee Jin, Dionnet L Bhatti, Ko-Woon Lee, Lucian Medrihan, Jia Cheng, Jing Wei, Ping Zhong, Zhen Yan, Cassandra Kooiker, Claire Song, Jung-Hyuck Ahn, Gerald J Obermair, Amy Lee, Jodi Gresack, Paul Greengard, Yong Kim
Ahnak scaffolds p11/Anxa2 complex and L-type voltage-gated calcium channel and modulates depressive behavior. Molecular psychiatry 25 (5) (2019)
Jennifer A Martin, Craig T Werner, Swarup Mitra, Ping Zhong, Zi-Jun Wang, Pedro H Gobira, Andrew F Stewart, Jay Zhang, Kyra Erias, Justin N Siemian, Devin Hagarty, Lauren E Mueller, Rachael L Neve, Jun-Xu Li, Ramesh Chandra, Karen C Dietz, Mary Kay Lobo, Amy M Gancarz, Zhen Yan, David M Dietz
A novel role for the actin-binding protein drebrin in regulating opiate addiction. Nature communications 10 (1) (2019)
Zi-Jun Wang, Ping Zhong, Kaijie Ma, Ji-Seon Seo, Fengwei Yang, Zihua Hu, Freddy Zhang, Lin Lin, Jie Wang, Tao Liu, Emmanuel Matas, Paul Greengard, Zhen Yan
Amelioration of autism-like social deficits by targeting histone methyltransferases EHMT1/2 in Shank3-deficient mice. Molecular psychiatry 25 (10) (2019)
Luye Qin, Kaijie Ma, Zi-Jun Wang, Zihua Hu, Emmanuel Matas, Jing Wei, Zhen Yan
Social deficits in Shank3-deficient mouse models of autism are rescued by histone deacetylase (HDAC) inhibition. Nature neuroscience 21 (4) (2018)
Wei Wang, Benjamin A Rein, Freddy Zhang, Tao Tan, Ping Zhong, Luye Qin, Zhen Yan
Chemogenetic Activation of Prefrontal Cortex Rescues Synaptic and Behavioral Deficits in a Mouse Model of 16p11.2 Deletion Syndrome. The Journal of neuroscience : the official journal of the Society for Neuroscience 38 (26) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

Zhen Yan