Li Shen (L Shen)

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2014-2023
Publications (10 Years): 37

Top Topics

Prefrontal Cortex

Top Venues

Science advances

Nature communications

Nature neuroscience

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

This page only lists publications with an associated author ORCID identifier.

Publications

Caleb J Browne, Rita Futamura, Angélica Minier-Toribio, Emily M Hicks, Aarthi Ramakrishnan, Freddyson J Martínez-Rivera, Molly Estill, Arthur Godino, Eric M Parise, Angelica Torres-Berrio, Ashley M Cunningham, Peter J Hamilton, Deena M Walker, Laura M Huckins, Yasmin L Hurd, Li Shen, Eric J Nestler
Transcriptional signatures of heroin intake and relapse throughout the brain reward circuitry in male mice. Science advances 9 (23) (2023)
Vignesh Amal Arasu, Laurel A Habel, Ninah S Achacoso, Diana S M Buist, Jason B Cord, Laura J Esserman, Nola M Hylton, Medellena Maria Glymour, John Kornak, Lawrence H Kushi, Donald A Lewis, Vincent X Liu, Caitlin M Lydon, Diana L Miglioretti, Daniel A Navarro, Albert Pu, Li Shen, Weiva Sieh, Hyo-Chun Yoon, Catherine Lee
Comparison of Mammography AI Algorithms with a Clinical Risk Model for 5-year Breast Cancer Risk Prediction: An Observational Study. Radiology 307 (5) (2023)
Philipp Mews, Ashley M Cunningham, Joseph Scarpa, Aarthi Ramakrishnan, Emily M Hicks, Sarah Bolnick, Susanna Garamszegi, Li Shen, Deborah C Mash, Eric J Nestler
Convergent abnormalities in striatal gene networks in human cocaine use disorder and mouse cocaine administration models. Science advances 9 (6) (2023)
Scott J Russo, Flurin Cathomas, Hsiao-Yun Lin, Kenny Chan, Long Li, Romain Durand-de Cuttoli, Lyonna F Parise, Antonio Aubry, Samer Muhareb, Fiona Desland, Yusuke Shimo, Aarthi Ramakrishnan, Molly Estill, Carmen Ferrer-Perez, Eric Parise, Jun Wang, Allison Sowa, William Janssen, Sara Costi, Adeeb Rahman, Nicolas Fernandez, Filip K Swirski, Eric J Nestler, Li Shen, Miriam Merad, James W Murrough
Peripheral immune-derived matrix metalloproteinase promotes stress susceptibility. Research square (2023)
Philipp Mews, Ashley M Cunningham, Joseph Scarpa, Aarthi Ramakrishnan, Emily M Hicks, Sarah Bolnick, Susanna Garamszegi, Li Shen, Deborah C Mash, Eric J Nestler
Convergent abnormalities in striatal gene networks in human cocaine use disorder and mouse cocaine administration models. Science advances 9 (6) (2023)
Randal A Serafini, Molly Estill, Elizabeth A Pekarskaya, Farhana Sakloth, Li Shen, Jonathan A Javitch, Venetia Zachariou
Tianeptine promotes lasting antiallodynic effects in a mouse model of neuropathic pain. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology (2023)
Philipp Mews, Ashley M Cunningham, Joseph Scarpa, Aarthi Ramakrishnan, Emily M Hicks, Sarah Bolnick, Susanna Garamszegi, Li Shen, Deborah C Mash, Eric J Nestler
Convergent abnormalities in striatal gene networks in human cocaine use disorder and mouse cocaine administration models. Science advances 9 (6) (2023)
Scott J Russo, Flurin Cathomas, Hsiao-Yun Lin, Kenny Chan, Long Li, Romain Durand-de Cuttoli, Lyonna F Parise, Antonio Aubry, Samer Muhareb, Fiona Desland, Yusuke Shimo, Aarthi Ramakrishnan, Molly Estill, Carmen Ferrer-Perez, Eric Parise, Jun Wang, Allison Sowa, William Janssen, Sara Costi, Adeeb Rahman, Nicolas Fernandez, Filip K Swirski, Eric J Nestler, Li Shen, Miriam Merad, James W Murrough
Peripheral immune-derived matrix metalloproteinase promotes stress susceptibility. Research square (2023)
Kerri D Pryce, Randal A Serafini, Aarthi Ramakrishnan, Andrew Nicolais, Ilinca M Giosan, Claire Polizu, Angelica Torres-Berrio, Sreeya Vuppala, Hope Kronman, Anne Ruiz, Sevasti Gaspari, Catherine Jensen Peña, Farhana Sakloth, Vasiliki Mitsi, John van Duzer, Ralph Mazitschek, Matthew Jarpe, Li Shen, Eric J Nestler, Venetia Zachariou
Oxycodone withdrawal induces HDAC1/HDAC2-dependent transcriptional maladaptations in the reward pathway in a mouse model of peripheral nerve injury. Nature neuroscience (2023)
Scott J Russo, Flurin Cathomas, Hsiao-Yun Lin, Kenny Chan, Long Li, Romain Durand-de Cuttoli, Lyonna F Parise, Antonio Aubry, Samer Muhareb, Fiona Desland, Yusuke Shimo, Aarthi Ramakrishnan, Molly Estill, Carmen Ferrer-Perez, Eric Parise, Jun Wang, Allison Sowa, William Janssen, Sara Costi, Adeeb Rahman, Nicolas Fernandez, Filip K Swirski, Eric J Nestler, Li Shen, Miriam Merad, James W Murrough
Peripheral immune-derived matrix metalloproteinase promotes stress susceptibility. Research square (2023)
Philipp Mews, Ashley M Cunningham, Joseph Scarpa, Aarthi Ramakrishnan, Emily M Hicks, Sarah Bolnick, Susanna Garamszegi, Li Shen, Deborah C Mash, Eric J Nestler
Convergent abnormalities in striatal gene networks in human cocaine use disorder and mouse cocaine administration models. Science advances 9 (6) (2023)
Dalia Halawani, Yiqun Wang, Aarthi Ramakrishnan, Molly Estill, Xijing He, Li Shen, Roland H Friedel, Hongyan Zou
Circadian clock regulator Bmal1 gates axon regeneration via Tet3 epigenetics in mouse sensory neurons. Nature communications 14 (1) (2023)
Yiqun Wang, Dalia Halawani, Molly Estill, Aarthi Ramakrishnan, Li Shen, Roland H Friedel, Hongyan Zou
Aryl hydrocarbon receptor restricts axon regeneration of DRG neurons in response to injury. bioRxiv : the preprint server for biology (2023)
Sasha L Fulton, Wendy Wenderski, Ashley E Lepack, Andrew L Eagle, Tomas Fanutza, Ryan M Bastle, Aarthi Ramakrishnan, Emma C Hays, Arianna Neal, Jaroslav Bendl, Lorna A Farrelly, Amni Al-Kachak, Yang Lyu, Bulent Cetin, Jennifer C Chan, Tina N Tran, Rachael L Neve, Randall J Roper, Kristen J Brennand, Panagiotis Roussos, John C Schimenti, Allyson K Friedman, Li Shen, Robert D Blitzer, Alfred J Robison, Gerald R Crabtree, Ian Maze
Rescue of deficits by Brwd1 copy number restoration in the Ts65Dn mouse model of Down syndrome. Nature communications 13 (1) (2022)
Yentl Y van der Zee, Lars M T Eijssen, Philipp Mews, Aarthi Ramakrishnan, Kelvin Alvarez, Casey K Lardner, Hannah M Cates, Deena M Walker, Angelica Torres-Berrio, Caleb J Browne, Ashley Cunningham, Flurin Cathomas, Hope Kronman, Eric M Parise, Laurence de Nijs, Li Shen, James W Murrough, Bart P F Rutten, Eric J Nestler, Orna Issler
Blood miR-144-3p: a novel diagnostic and therapeutic tool for depression. Molecular psychiatry (2022)
Lorna A Farrelly, Shuangping Zheng, Nadine Schrode, Aaron Topol, Natarajan V Bhanu, Ryan M Bastle, Aarthi Ramakrishnan, Jennifer C Chan, Bulent Cetin, Erin Flaherty, Li Shen, Kelly Gleason, Carol A Tamminga, Benjamin A Garcia, Haitao Li, Kristen J Brennand, Ian Maze
Chromatin profiling in human neurons reveals aberrant roles for histone acetylation and BET family proteins in schizophrenia. Nature communications 13 (1) (2022)
Orna Issler, Yentl Y van der Zee, Aarthi Ramakrishnan, Sun-Hui Xia, Alexander K Zinsmaier, Chunfeng Tan, Wei Li, Caleb J Browne, Deena M Walker, Marine Salery, Angelica Torres-Berrio, Rita Futamura, Julia E Duffy, Benoit Labonte, Matthew J Girgenti, Carol A Tamminga, Jeffrey L Dupree, Yan Dong, James W Murrough, Li Shen, Eric J Nestler
The long noncoding RNA FEDORA is a cell type- and sex-specific regulator of depression. Science advances 8 (48) (2022)
Sandhya Chandrasekaran, Sergio Espeso-Gil, Yong-Hwee Eddie Loh, Behnam Javidfar, Bibi Kassim, Yueyan Zhu, Yuan Zhang, Yuhao Dong, Lucy K Bicks, Haixin Li, Prashanth Rajarajan, Cyril J Peter, Daijing Sun, Esperanza Agullo-Pascual, Marina Iskhakova, Molly Estill, Bluma J Lesch, Li Shen, Yan Jiang, Schahram Akbarian
Neuron-specific chromosomal megadomain organization is adaptive to recent retrotransposon expansions. Nature communications 12 (1) (2021)
Chrystian Junqueira Alves, Rafael Dariolli, Jonathan Haydak, Sangjo Kang, Theodore Hannah, Robert J Wiener, Stefanie DeFronzo, Rut Tejero, Gabriele L Gusella, Aarthi Ramakrishnan, Rodrigo Alves Dias, Alexandre Wojcinski, Santosh Kesari, Li Shen, Eric A Sobie, José Paulo Rodrigues Furtado de Mendonça, Evren U Azeloglu, Hongyan Zou, Roland H Friedel
Plexin-B2 orchestrates collective stem cell dynamics via actomyosin contractility, cytoskeletal tension and adhesion. Nature communications 12 (1) (2021)
Shalaka Wahane, Xianxiao Zhou, Xiang Zhou, Lei Guo, Marie-Sophie Friedl, Michael Kluge, Aarthi Ramakrishnan, Li Shen, Caroline C Friedel, Bin Zhang, Roland H Friedel, Hongyan Zou
Diversified transcriptional responses of myeloid and glial cells in spinal cord injury shaped by HDAC3 activity. Science advances 7 (9) (2021)
Hope Kronman, Angélica Torres-Berrío, Simone Sidoli, Orna Issler, Arthur Godino, Aarthi Ramakrishnan, Philipp Mews, Casey K Lardner, Eric M Parise, Deena M Walker, Yentl Y van der Zee, Caleb J Browne, Brittany F Boyce, Rachael Neve, Benjamin A Garcia, Li Shen, Catherine Jensen Peña, Eric J Nestler
Long-term behavioral and cell-type-specific molecular effects of early life stress are mediated by H3K79me2 dynamics in medium spiny neurons. Nature neuroscience 24 (5) (2021)
Ashley E Lepack, Craig T Werner, Andrew F Stewart, Sasha L Fulton, Ping Zhong, Lorna A Farrelly, Alexander C W Smith, Aarthi Ramakrishnan, Yang Lyu, Ryan M Bastle, Jennifer A Martin, Swarup Mitra, Richard M O'Connor, Zi-Jun Wang, Henrik Molina, Gustavo Turecki, Li Shen, Zhen Yan, Erin S Calipari, David M Dietz, Paul J Kenny, Ian Maze
Dopaminylation of histone H3 in ventral tegmental area regulates cocaine seeking. Science (New York, N.Y.) 368 (6487) (2020)
Craig T Werner, S Mitra, Jennifer A Martin, Andrew F Stewart, Ashley E Lepack, Aarthi Ramakrishnan, P H Gobira, Z-J Wang, R L Neve, A M Gancarz, Li Shen, I Maze, David M Dietz
Ubiquitin-proteasomal regulation of chromatin remodeler INO80 in the nucleus accumbens mediates persistent cocaine craving. Science advances 5 (10) (2019)
Catherine Jensen Peña, Milo Smith, Aarthi Ramakrishnan, Hannah M Cates, Rosemary C Bagot, Hope G Kronman, Bhakti Patel, Austin B Chang, Immanuel Purushothaman, Joel Dudley, Hirofumi Morishita, Li Shen, Eric J Nestler
Early life stress alters transcriptomic patterning across reward circuitry in male and female mice. Nature communications 10 (1) (2019)
Zachary S Lorsch, Peter J Hamilton, Aarthi Ramakrishnan, Eric M Parise, Marine Salery, William J Wright, Ashley E Lepack, Philipp Mews, Orna Issler, Andrew McKenzie, Xianxiao Zhou, Lyonna F Parise, Stephen T Pirpinias, Idelisse Ortiz Torres, Hope G Kronman, Sarah E Montgomery, Yong-Hwee Eddie Loh, Benoit Labonté, Andrew Conkey, Ann E Symonds, Rachael L Neve, Gustavo Turecki, Ian Maze, Yan Dong, Bin Zhang, Li Shen, Rosemary C Bagot, Eric J Nestler
Stress resilience is promoted by a Zfp189-driven transcriptional network in prefrontal cortex. Nature neuroscience 22 (9) (2019)
Li Shen, Laurie R Margolies, Joseph H Rothstein, Eugene Fluder, Russell B McBride, Weiva Sieh
Deep Learning to Improve Breast Cancer Detection on Screening Mammography. Scientific reports 9 (1) (2019)
Zachary S Lorsch, Yong-Hwee Eddie Loh, Immanuel Purushothaman, Deena M Walker, Eric M Parise, Marine Salery, Michael E Cahill, Georgia E Hodes, Madeline L Pfau, Hope Kronman, Peter J Hamilton, Orna Issler, Benoit Labonté, Ann E Symonds, Matthew Zucker, Tie-Yuan Zhang, Michael J Meaney, Scott J Russo, Li Shen, Rosemary C Bagot, Eric J Nestler
Estrogen receptor α drives pro-resilient transcription in mouse models of depression. Nature communications 9 (1) (2018)
Hannah M Cates, Xuan Li, Immanuel Purushothaman, Pamela J Kennedy, Li Shen, Yavin Shaham, Eric J Nestler
Genome-wide transcriptional profiling of central amygdala and orbitofrontal cortex during incubation of methamphetamine craving. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 43 (12) (2018)
Hannah M Cates, Rosemary C Bagot, Elizabeth A Heller, Immanuel Purushothaman, Casey K Lardner, Deena M Walker, Catherine J Peña, Rachael L Neve, Li Shen, Eric J Nestler
A novel role for E2F3b in regulating cocaine action in the prefrontal cortex. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 44 (4) (2018)
Catherine Jensen Peña, Hope G Kronman, Deena M Walker, Hannah M Cates, Rosemary C Bagot, Immanuel Purushothaman, Orna Issler, Yong-Hwee Eddie Loh, Tin Leong, Drew D Kiraly, Emma Goodman, Rachael L Neve, Li Shen, Eric J Nestler
Early life stress confers lifelong stress susceptibility in mice via ventral tegmental area OTX2. Science (New York, N.Y.) 356 (6343) (2018)
Pinar Ayata, Ana Badimon, Hayley J Strasburger, Mary Kaye Duff, Sarah E Montgomery, Yong-Hwee E Loh, Anja Ebert, Anna A Pimenova, Brianna R Ramirez, Andrew T Chan, Josefa M Sullivan, Immanuel Purushothaman, Joseph R Scarpa, Alison Mary Goate, Meinrad Busslinger, Li Shen, Bojan Losic, Anne Schaefer
Epigenetic regulation of brain region-specific microglia clearance activity. Nature neuroscience 21 (8) (2018)
Yan Jiang, Yong-Hwee Eddie Loh, Prashanth Rajarajan, Teruyoshi Hirayama, Will Liao, Bibi S Kassim, Behnam Javidfar, Brigham J Hartley, Lisa Kleofas, Royce B Park, Benoit Labonte, Seok-Man Ho, Sandhya Chandrasekaran, Catherine Do, Brianna R Ramirez, Cyril J Peter, Julia T C W, Brian M Safaie, Hirofumi Morishita, Panos Roussos, Eric J Nestler, Anne Schaefer, Benjamin Tycko, Kristen J Brennand, Takeshi Yagi, Li Shen, Schahram Akbarian
The methyltransferase SETDB1 regulates a large neuron-specific topological chromatin domain. Nature genetics 49 (8) (2017)
Jian Feng, Catherine J Pena, Immanuel Purushothaman, Olivia Engmann, Deena Walker, Amber N Brown, Orna Issler, Marie Doyle, Eileen Harrigan, Ezekiell Mouzon, Vincent Vialou, Li Shen, Meelad M Dawlaty, Rudolf Jaenisch, Eric J Nestler
Tet1 in Nucleus Accumbens Opposes Depression- and Anxiety-Like Behaviors. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 42 (8) (2017)
Benoit Labonté, Olivia Engmann, Immanuel Purushothaman, Caroline Menard, Junshi Wang, Chunfeng Tan, Joseph R Scarpa, Gregory Moy, Yong-Hwee E Loh, Michael Cahill, Zachary S Lorsch, Peter J Hamilton, Erin S Calipari, Georgia E Hodes, Orna Issler, Hope Kronman, Madeline Pfau, Aleksandar L J Obradovic, Yan Dong, Rachael L Neve, Scott Russo, Andrew Kazarskis, Carol Tamminga, Naguib Mechawar, Gustavo Turecki, Bin Zhang, Li Shen, Eric J Nestler
Sex-specific transcriptional signatures in human depression. Nature medicine 23 (9) (2017)
Giannina Descalzi, Vasiliki Mitsi, Immanuel Purushothaman, Sevasti Gaspari, Kleopatra Avrampou, Yong-Hwee Eddie Loh, Li Shen, Venetia Zachariou
Neuropathic pain promotes adaptive changes in gene expression in brain networks involved in stress and depression. Science signaling 10 (471) (2017)
Erica Y Shen, Yan Jiang, Behnam Javidfar, Bibi Kassim, Yong-Hwee E Loh, Qi Ma, Amanda C Mitchell, Venu Pothula, A Francis Stewart, Patricia Ernst, Wei-Dong Yao, Gilles Martin, Li Shen, Mira Jakovcevski, Schahram Akbarian
Neuronal Deletion of Kmt2a/Mll1 Histone Methyltransferase in Ventral Striatum is Associated with Defective Spike-Timing-Dependent Striatal Synaptic Plasticity, Altered Response to Dopaminergic Drugs, and Increased Anxiety. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 41 (13) (2016)
Jian Feng, Ningyi Shao, Keith E Szulwach, Vincent Vialou, Jimmy Huynh, Chun Zhong, Thuc Le, Deveroux Ferguson, Michael E Cahill, Yujing Li, Ja Wook Koo, Efrain Ribeiro, Benoit Labonte, Benjamin M Laitman, David Estey, Victoria Stockman, Pamela Kennedy, Thomas Couroussé, Isaac Mensah, Gustavo Turecki, Kym F Faull, Guo-li Ming, Hongjun Song, Guoping Fan, Patrizia Casaccia, Li Shen, Peng Jin, Eric J Nestler
Role of Tet1 and 5-hydroxymethylcytosine in cocaine action. Nature neuroscience 18 (4) (2015)
Elizabeth A Heller, Hannah M Cates, Catherine J Peña, Haosheng Sun, Ningyi Shao, Jian Feng, Sam A Golden, James P Herman, Jessica J Walsh, Michelle Mazei-Robison, Deveroux Ferguson, Scott Knight, Mark A Gerber, Christian Nievera, Ming-Hu Han, Scott J Russo, Carol S Tamminga, Rachael L Neve, Li Shen, H Steve Zhang, Feng Zhang, Eric J Nestler
Locus-specific epigenetic remodeling controls addiction- and depression-related behaviors. Nature neuroscience 17 (12) (2014)
Ian Maze, Li Shen, Bin Zhang, Benjamin A Garcia, Ningyi Shao, Amanda Mitchell, HaoSheng Sun, Schahram Akbarian, C David Allis, Eric J Nestler
Analytical tools and current challenges in the modern era of neuroepigenomics. Nature neuroscience 17 (11) (2014)