Zheng-Xiong Xi

Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2014-2024
Publications (10 Years): 46

Top Topics

Prefrontal Cortex

Top Venues

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

The Journal of neuroscience : the official journal of the Society for Neuroscience

Translational psychiatry

Proceedings of the National Academy of Sciences of the United States of America

This page only lists publications with an associated author ORCID identifier.

Publications

Rui Song, Omar Soler-Cedeno, Zheng-Xiong Xi
Optical Intracranial Self-Stimulation (oICSS): A New Behavioral Model for Studying Drug Reward and Aversion in Rodents. International journal of molecular sciences 25 (6) (2024)
Yi He, Hui Shen, Guo-Hua Bi, Hai-Ying Zhang, Omar Soler-Cedeño, Hannah Alton, Yihong Yang, Zheng-Xiong Xi
GPR55 is expressed in glutamate neurons and functionally modulates drug taking and seeking in rats and mice. Translational psychiatry 14 (1) (2024)
Yi He, Hui Shen, Guo-Hua Bi, Hai-Ying Zhang, Omar Soler-Cedeño, Hannah Alton, Yihong Yang, Zheng-Xiong Xi
GPR55 is expressed in glutamate neurons and functionally modulates drug taking and seeking in rats and mice. Translational psychiatry 14 (1) (2024)
Rui Song, Omar Soler-Cedeno, Zheng-Xiong Xi
Optical Intracranial Self-Stimulation (oICSS): A New Behavioral Model for Studying Drug Reward and Aversion in Rodents. International journal of molecular sciences 25 (6) (2024)
Omar Soler-Cedeno, Hannah Alton, Guo-Hua Bi, Emily Linz, Lipin Ji, Alexandros Makriyannis, Zheng-Xiong Xi
AM6527, a neutral CB1 receptor antagonist, suppresses opioid taking and seeking, as well as cocaine seeking in rodents without aversive effects. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology (2024)
Marios C Panayi, Shohan Shetty, Micaela Porod, Lisette Bahena, Zheng-Xiong Xi, Amy Hauck Newman, Geoffrey Schoenbaum
The selective D 3 Receptor antagonist VK4-116 reverses loss of insight caused by self-administration of cocaine in rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology (2024)
Omar Soler-Cedeno, Hannah Alton, Guo-Hua Bi, Emily Linz, Lipin Ji, Alexandros Makriyannis, Zheng-Xiong Xi
AM6527, a neutral CB1 receptor antagonist, suppresses opioid taking and seeking, as well as cocaine seeking in rodents without aversive effects. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology (2024)
Yi He, Hui Shen, Guo-Hua Bi, Hai-Ying Zhang, Omar Soler-Cedeño, Hannah Alton, Yihong Yang, Zheng-Xiong Xi
GPR55 is expressed in glutamate neurons and functionally modulates drug taking and seeking in rats and mice. Translational psychiatry 14 (1) (2024)
Marios C Panayi, Shohan Shetty, Micaela Porod, Lisette Bahena, Zheng-Xiong Xi, Amy Hauck Newman, Geoffrey Schoenbaum
The selective D 3 Receptor antagonist VK4-116 reverses loss of insight caused by self-administration of cocaine in rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 49 (10) (2024)
Marios C Panayi, Shohan Shetty, Micaela Porod, Lisette Bahena, Zheng-Xiong Xi, Amy Hauck Newman, Geoffrey Schoenbaum
The selective D 3 Receptor antagonist VK4-116 reverses loss of insight caused by self-administration of cocaine in rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 49 (10) (2024)
Marios C Panayi, Shohan Shetty, Micaela Porod, Lisette Bahena, Zheng-Xiong Xi, Amy Hauck Newman, Geoffrey Schoenbaum
The selective D 3 Receptor antagonist VK4-116 reverses loss of insight caused by self-administration of cocaine in rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 49 (10) (2024)
Marios C Panayi, Shohan Shetty, Micaela Porod, Lisette Bahena, Zheng-Xiong Xi, Amy Hauck Newman, Geoffrey Schoenbaum
The selective D 3 Receptor antagonist VK4-116 reverses loss of insight caused by self-administration of cocaine in rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 49 (10) (2024)
Yi He, Hui Shen, Guo-Hua Bi, Hai-Ying Zhang, Omar Soler-Cedeño, Hannah Alton, Yihong Yang, Zheng-Xiong Xi
GPR55 is expressed in glutamate neurons and functionally modulates drug taking and seeking in rats and mice. Translational psychiatry 14 (1) (2024)
Yi He, Hui Shen, Guo-Hua Bi, Hai-Ying Zhang, Omar Soler-Cedeño, Hannah Alton, Yihong Yang, Zheng-Xiong Xi
GPR55 is expressed in glutamate neurons and functionally modulates drug taking and seeking in rats and mice. Translational psychiatry 14 (1) (2024)
Rui Song, Omar Soler-Cedeno, Zheng-Xiong Xi
Optical Intracranial Self-Stimulation (oICSS): A New Behavioral Model for Studying Drug Reward and Aversion in Rodents. International journal of molecular sciences 25 (6) (2024)
Yi He, Hui Shen, Guo-Hua Bi, Hai-Ying Zhang, Omar Soler-Cedeño, Hannah Alton, Yihong Yang, Zheng-Xiong Xi
GPR55 is expressed in glutamate neurons and functionally modulates drug taking and seeking in rats and mice. Translational psychiatry 14 (1) (2024)
Zheng-Xiong Xi, Yi He, Hui Shen, Guo-Hua Bi, Hai-Ying Zhang, Omar Soler-Cedeno, Hannah Alton, Yihong Yang
GPR55 is expressed in glutamate neurons and functionally modulates nicotine taking and seeking in rats and mice. Research square (2023)
Briana Hempel, Madeline Crissman, Sruti Pari, Benjamin Klein, Guo-Hua Bi, Hannah Alton, Zheng-Xiong Xi
PPARα and PPARγ are expressed in midbrain dopamine neurons and modulate dopamine- and cannabinoid-mediated behavior in mice. Molecular psychiatry (2023)
Xiao Han, Ying Liang, Briana Hempel, Chloe J Jordan, Hui Shen, Guo-Hua Bi, Jin Li, Zheng-Xiong Xi
Cannabinoid CB1 Receptors Are Expressed in a Subset of Dopamine Neurons and Underlie Cannabinoid-Induced Aversion, Hypoactivity, and Anxiolytic Effects in Mice. The Journal of neuroscience : the official journal of the Society for Neuroscience 43 (3) (2022)
Hong-Ju Yang, Briana J Hempel, Guo-Hua Bi, Yi He, Hai-Ying Zhang, Eliot L Gardner, Zheng-Xiong Xi
Elevation of Extracellular Glutamate by Blockade of Astrocyte Glutamate Transporters Inhibits Cocaine Reinforcement in Rats via a NMDA-GluN2B Receptor Mechanism. The Journal of neuroscience : the official journal of the Society for Neuroscience 42 (11) (2022)
Xiao Han, Ying Liang, Briana Hempel, Chloe J Jordan, Hui Shen, Guo-Hua Bi, Jin Li, Zheng-Xiong Xi
Cannabinoid CB1 Receptors Are Expressed in a Subset of Dopamine Neurons and Underlie Cannabinoid-Induced Aversion, Hypoactivity, and Anxiolytic Effects in Mice. The Journal of neuroscience : the official journal of the Society for Neuroscience 43 (3) (2022)
Omar Soler-Cedeno, Zheng-Xiong Xi
Neutral CB1 Receptor Antagonists as Pharmacotherapies for Substance Use Disorders: Rationale, Evidence, and Challenge. Cells 11 (20) (2022)
Xiao Han, Ying Liang, Briana Hempel, Chloe Jordan, Hui Shen, Guo-Hua Bi, Jin Li, Zheng-Xiong Xi
Cannabinoid CB1 Receptors Are Expressed in a Subset of Dopamine Neurons and Underlie Cannabinoid-Induced Aversion, Hypoactivity, and Anxiolytic Effects in Mice. The Journal of neuroscience : the official journal of the Society for Neuroscience (2022)
Yi He, Graziella Madeo, Ying Liang, Cindy Zhang, Briana Hempel, Xiaojie Liu, Lianwei Mu, Shui Liu, Guo-Hua Bi, Ewa Galaj, Hai-Ying Zhang, Hui Shen, Ross A McDevitt, Eliot L Gardner, Qing-Song Liu, Zheng-Xiong Xi
A red nucleus-VTA glutamate pathway underlies exercise reward and the therapeutic effect of exercise on cocaine use. Science advances 8 (35) (2022)
Xiao Han, Ying Liang, Briana Hempel, Chloe J Jordan, Hui Shen, Guo-Hua Bi, Jin Li, Zheng-Xiong Xi
Cannabinoid CB1 Receptors Are Expressed in a Subset of Dopamine Neurons and Underlie Cannabinoid-Induced Aversion, Hypoactivity, and Anxiolytic Effects in Mice. The Journal of neuroscience : the official journal of the Society for Neuroscience 43 (3) (2022)
Xiao Han, Ying Liang, Briana Hempel, Chloe J Jordan, Hui Shen, Guo-Hua Bi, Jin Li, Zheng-Xiong Xi
Cannabinoid CB1 Receptors Are Expressed in a Subset of Dopamine Neurons and Underlie Cannabinoid-Induced Aversion, Hypoactivity, and Anxiolytic Effects in Mice. The Journal of neuroscience : the official journal of the Society for Neuroscience 43 (3) (2022)
Rebeca Mejias, Juan Jose Rodriguez Gotor, Minae Niwa, Irina N Krasnova, Abby Adamczyk, Mei Han, Gareth M Thomas, Zheng-Xiong Xi, Richard L Huganir, Mikhail V Pletnikov, Akira Sawa, Jean-Lud Cadet, Tao Wang
Increased novelty-induced locomotion, sensitivity to amphetamine, and extracellular dopamine in striatum of Zdhhc15-deficient mice. Translational psychiatry 11 (1) (2021)
Bree A Humburg, Chloe J Jordan, Hai-Ying Zhang, Hui Shen, Xiao Han, Guo-Hua Bi, Briana Hempel, Ewa Galaj, Michael H Baumann, Zheng-Xiong Xi
Optogenetic brain-stimulation reward: A new procedure to re-evaluate the rewarding versus aversive effects of cannabinoids in dopamine transporter-Cre mice. Addiction biology 26 (4) (2021)
Xiao-Fei Wang, Ewa Galaj, Guo-Hua Bi, Cindy Zhang, Yi He, Jia Zhan, Michael H Bauman, Eliot L Gardner, Zheng-Xiong Xi
Different receptor mechanisms underlying phytocannabinoid- versus synthetic cannabinoid-induced tetrad effects: Opposite roles of CB1 /CB2 versus GPR55 receptors. British journal of pharmacology 177 (8) (2020)
Chloe J Jordan, Yi He, Guo-Hua Bi, Zhi-Bing You, Jianjing Cao, Zheng-Xiong Xi, Amy Hauck Newman
(±)VK4-40, a novel dopamine D3 receptor partial agonist, attenuates cocaine reward and relapse in rodents. British journal of pharmacology 177 (20) (2020)
Yi He, Ewa Galaj, Guo-Hua Bi, Xiao-Fei Wang, Eliot L Gardner, Zheng-Xiong Xi
β-Caryophyllene, a dietary terpenoid, inhibits nicotine taking and nicotine seeking in rodents. British journal of pharmacology 177 (9) (2020)
Ewa Galaj, Xiao Han, Hui Shen, Chloe J Jordan, Yi He, Bree Humburg, Guo-Hua Bi, Zheng-Xiong Xi
Dissecting the Role of GABA Neurons in the VTA versus SNr in Opioid Reward. The Journal of neuroscience : the official journal of the Society for Neuroscience 40 (46) (2020)
Ewa Galaj, Zheng-Xiong Xi
Possible Receptor Mechanisms Underlying Cannabidiol Effects on Addictive-like Behaviors in Experimental Animals. International journal of molecular sciences 22 (1) (2020)
Ewa Galaj, Zheng-Xiong Xi
Potential of Cannabinoid Receptor Ligands as Treatment for Substance Use Disorders. CNS drugs 33 (10) (2020)
Ewa Galaj, Guo-Hua Bi, Allamar Moore, Kai Chen, Yi He, Eliot Gardner, Zheng-Xiong Xi
Beta-caryophyllene inhibits cocaine addiction-related behavior by activation of PPARα and PPARγ: repurposing a FDA-approved food additive for cocaine use disorder. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 46 (4) (2020)
Zheng-Xiong Xi, Pretal Muldoon, Xiao-Fei Wang, Guo-Hua Bi, M Imad Damaj, Aron H Lichtman, Roger G Pertwee, Eliot L Gardner
Δ8 -Tetrahydrocannabivarin has potent anti-nicotine effects in several rodent models of nicotine dependence. British journal of pharmacology 176 (24) (2019)
Guo-Hua Bi, Ewa Galaj, Yi He, Zheng-Xiong Xi
Cannabidiol inhibits sucrose self-administration by CB1 and CB2 receptor mechanisms in rodents. Addiction biology 25 (4) (2019)
Guo-Hua Bi, Ewa Galaj, Yi He, Zheng-Xiong Xi
Cannabidiol inhibits sucrose self-administration by CB1 and CB2 receptor mechanisms in rodents. Addiction biology 25 (4) (2019)
Amy Hauck Newman, Jianjing Cao, Jacqueline D Keighron, Chloe J Jordan, Guo-Hua Bi, Ying Liang, Ara M Abramyan, Alicia J Avelar, Christopher W Tschumi, Michael J Beckstead, Lei Shi, Gianluigi Tanda, Zheng-Xiong Xi
Translating the atypical dopamine uptake inhibitor hypothesis toward therapeutics for treatment of psychostimulant use disorders. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 44 (8) (2019)
George R Uhl, Maria J Martinez, Paul Paik, Agnieszka Sulima, Guo-Hua Bi, Malliga R Iyer, Eliot Gardner, Kenner C Rice, Zheng-Xiong Xi
Cocaine reward is reduced by decreased expression of receptor-type protein tyrosine phosphatase D (PTPRD) and by a novel PTPRD antagonist. Proceedings of the National Academy of Sciences of the United States of America 115 (45) (2018)
Jun-Tao Gao, Chloe J Jordan, Guo-Hua Bi, Yi He, Hong-Ju Yang, Eliot L Gardner, Zheng-Xiong Xi
Deletion of the type 2 metabotropic glutamate receptor increases heroin abuse vulnerability in transgenic rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 43 (13) (2018)
Hui Shen, Rosa Anna M Marino, Ross A McDevitt, Guo-Hua Bi, Kai Chen, Graziella Madeo, Pin-Tse Lee, Ying Liang, Lindsay M De Biase, Tsung-Ping Su, Zheng-Xiong Xi, Antonello Bonci
Genetic deletion of vesicular glutamate transporter in dopamine neurons increases vulnerability to MPTP-induced neurotoxicity in mice. Proceedings of the National Academy of Sciences of the United States of America 115 (49) (2018)
Hai-Ying Zhang, Guo-Hua Bi, Hong-Ju Yang, Yi He, Gilbert Xue, Jiajing Cao, Gianluigi Tanda, Eliot L Gardner, Amy Hauck Newman, Zheng-Xiong Xi
The Novel Modafinil Analog, JJC8-016, as a Potential Cocaine Abuse Pharmacotherapeutic. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 42 (9) (2017)
Xiao-Fei Wang, Elisabeth Barbier, Yi-Ting Chiu, Yi He, Jia Zhan, Guo-Hua Bi, Hai-Ying Zhang, Bo Feng, Lee-Yuan Liu-Chen, Jia Bei Wang, Zheng-Xiong Xi
T394A Mutation at the μ Opioid Receptor Blocks Opioid Tolerance and Increases Vulnerability to Heroin Self-Administration in Mice. The Journal of neuroscience : the official journal of the Society for Neuroscience 36 (40) (2017)
Zheng-Xiong Xi, Rui Song, Xia Li, Guan-Yi Lu, Xiao-Qing Peng, Yi He, Guo-Hua Bi, Siyuan Peter Sheng, Hong-Ju Yang, Haiying Zhang, Jin Li, Mark Froimowitz, Eliot L Gardner
CTDP-32476: A Promising Agonist Therapy for Treatment of Cocaine Addiction. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 42 (3) (2016)
Shang-Yi A Tsai, Jian-Ying Chuang, Meng-Shan Tsai, Xiao-Fei Wang, Zheng-Xiong Xi, Jan-Jong Hung, Wen-Chang Chang, Antonello Bonci, Tsung-Ping Su
Sigma-1 receptor mediates cocaine-induced transcriptional regulation by recruiting chromatin-remodeling factors at the nuclear envelope. Proceedings of the National Academy of Sciences of the United States of America 112 (47) (2015)
Hai-Ying Zhang, Ming Gao, Qing-Rong Liu, Guo-Hua Bi, Xia Li, Hong-Ju Yang, Eliot L Gardner, Jie Wu, Zheng-Xiong Xi
Cannabinoid CB2 receptors modulate midbrain dopamine neuronal activity and dopamine-related behavior in mice. Proceedings of the National Academy of Sciences of the United States of America 111 (46) (2014)