Richard L Huganir (Richard Huganir)

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 50

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

Nature communications

Science (New York, N.Y.)

bioRxiv : the preprint server for biology

Johns Hopkins School of Medicine

Cornell University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Johns Hopkins School of Medicine Oct 01 2015

United States

Director :: Kavli Neuroscience Discovery Institute at Johns Hopkins

Johns Hopkins School of Medicine Jan 01 2008

United States

Co-Director :: Brain Science Institute

Johns Hopkins School of Medicine Jan 01 2006

United States

Director :: Neuroscience

Johns Hopkins School of Medicine Jul 01 1993

United States

Professor :: Neuroscience

Howard Hughes Medical Institute Jul 01 1993 - Aug 31 2014

United States

Investigator :: Neuroscience

Johns Hopkins School of Medicine Jan 01 1988 - Jun 30 1993

United States

Associate Professor :: Neuroscience

Howard Hughes Medical Institute Jan 01 1988 - Jun 30 1993

United States

Associate Investigator :: Neuroscience

Rockefeller University Jul 31 1984 - Dec 31 1987

United States

Assistant Professor :: Molecular and Cellular Neuroscience

Rockefeller University Jul 01 1983 - Jul 31 1984

United States

Postdoctoral Fellow :: Molecular and Cellular Neuroscience

Yale University Feb 01 1982 - Jun 30 1983

United States

Postdoctoral Fellow :: Pharmacology

Education History

Cornell University Aug 31 1977 - May 31 1982

United States

PHD :: Biochemistry, Molecular and Cell Biology

Publications

W Dylan Hale, Alejandra Montaño Romero, Cuauhtemoc U Gonzalez, Vasanthi Jayaraman, Albert Y Lau, Richard L Huganir, Edward C Twomey
Allosteric competition and inhibition in AMPA receptors. Nature structural & molecular biology (2024)
Yoichi Araki, Kacey E Rajkovich, Elizabeth E Gerber, Timothy R Gamache, Richard C Johnson, Thanh Hai N Tran, Bian Liu, Qianwen Zhu, Ingie Hong, Alfredo Kirkwood, Richard L Huganir
SynGAP regulates synaptic plasticity and cognition independently of its catalytic activity. Science (New York, N.Y.) 383 (6686) (2024)
W Dylan Hale, Alejandra Montaño Romero, Cuauhtemoc U Gonzalez, Vasanthi Jayaraman, Albert Y Lau, Richard L Huganir, Edward C Twomey
Allosteric competition and inhibition in AMPA receptors. Nature structural & molecular biology (2024)
Yoichi Araki, Kacey E Rajkovich, Elizabeth E Gerber, Timothy R Gamache, Richard C Johnson, Thanh Hai N Tran, Bian Liu, Qianwen Zhu, Ingie Hong, Alfredo Kirkwood, Richard L Huganir
SynGAP regulates synaptic plasticity and cognition independently of its catalytic activity. Science (New York, N.Y.) 383 (6686) (2024)
Yoichi Araki, Kacey E Rajkovich, Elizabeth E Gerber, Timothy R Gamache, Richard C Johnson, Thanh Hai N Tran, Bian Liu, Qianwen Zhu, Ingie Hong, Alfredo Kirkwood, Richard L Huganir
SynGAP regulates synaptic plasticity and cognition independently of its catalytic activity. Science (New York, N.Y.) 383 (6686) (2024)
Thomas L Dunham, Julia R Wilkerson, Richard C Johnson, Richard L Huganir, Lenora J Volk
Modulation of GABA A receptor trafficking by WWC2 reveals class-specific mechanisms of synapse regulation by WWC family proteins. bioRxiv : the preprint server for biology (2024)
Yoichi Araki, Kacey E Rajkovich, Elizabeth E Gerber, Timothy R Gamache, Richard C Johnson, Thanh Hai N Tran, Bian Liu, Qianwen Zhu, Ingie Hong, Alfredo Kirkwood, Richard L Huganir
SynGAP regulates synaptic plasticity and cognition independently of its catalytic activity. Science (New York, N.Y.) 383 (6686) (2024)
Thomas L Dunham, Julia R Wilkerson, Richard C Johnson, Richard L Huganir, Lenora J Volk
Modulation of GABA A receptor trafficking by WWC2 reveals class-specific mechanisms of synapse regulation by WWC family proteins. bioRxiv : the preprint server for biology (2024)
Yoichi Araki, Kacey E Rajkovich, Elizabeth E Gerber, Timothy R Gamache, Richard C Johnson, Thanh Hai N Tran, Bian Liu, Qianwen Zhu, Ingie Hong, Alfredo Kirkwood, Richard L Huganir
SynGAP regulates synaptic plasticity and cognition independently of its catalytic activity. Science (New York, N.Y.) 383 (6686) (2024)
W Dylan Hale, Alejandra Montaño Romero, Cuauhtemoc U Gonzalez, Vasanthi Jayaraman, Albert Y Lau, Richard L Huganir, Edward C Twomey
Allosteric competition and inhibition in AMPA receptors. Nature structural & molecular biology (2024)
Yoichi Araki, Kacey E Rajkovich, Elizabeth E Gerber, Timothy R Gamache, Richard C Johnson, Thanh Hai N Tran, Bian Liu, Qianwen Zhu, Ingie Hong, Alfredo Kirkwood, Richard L Huganir
SynGAP regulates synaptic plasticity and cognition independently of its catalytic activity. Science (New York, N.Y.) 383 (6686) (2024)
W Dylan Hale, Alejandra Montaño Romero, Cuauhtemoc U Gonzalez, Vasanthi Jayaraman, Albert Y Lau, Richard L Huganir, Edward C Twomey
Allosteric Competition and Inhibition in AMPA Receptors. bioRxiv : the preprint server for biology (2023)
W Dylan Hale, Alejandra Montaño Romero, Richard L Huganir, Edward C Twomey
Structure of Transmembrane AMPA Receptor Regulatory Protein Subunit γ2. bioRxiv : the preprint server for biology (2023)
W Dylan Hale, Thomas C Südhof, Richard L Huganir
Engineered adhesion molecules drive synapse organization. Proceedings of the National Academy of Sciences of the United States of America 120 (3) (2023)
Oscar E Reyes Gaido, Nikoleta Pavlaki, Jonathan M Granger, Olurotimi O Mesubi, Bian Liu, Brian Leei Lin, Alan Long, David Walker, Joshua Mayourian, Kate L Schole, Chantelle E Terrillion, Lubika J Nkashama, Mohit M Hulsurkar, Lauren E Dorn, Kimberly M Ferrero, Richard L Huganir, Frank U Müller, Xander H T Wehrens, Jun O Liu, Elizabeth D Luczak, Vassilios J Bezzerides, Mark E Anderson
An improved reporter identifies ruxolitinib as a potent and cardioprotective CaMKII inhibitor. Science translational medicine 15 (701) (2023)
W Dylan Hale, Thomas C Südhof, Richard L Huganir
Engineered adhesion molecules drive synapse organization. Proceedings of the National Academy of Sciences of the United States of America 120 (3) (2023)
W Dylan Hale, Thomas C Südhof, Richard L Huganir
Engineered adhesion molecules drive synapse organization. Proceedings of the National Academy of Sciences of the United States of America 120 (3) (2023)
W Dylan Hale, Thomas C Südhof, Richard L Huganir
Engineered adhesion molecules drive synapse organization. Proceedings of the National Academy of Sciences of the United States of America 120 (3) (2023)
Yu Kang T Xu, Austin R Graves, Gabrielle I Coste, Richard L Huganir, Dwight E Bergles, Adam S Charles, Jeremias Sulam
Cross-modality supervised image restoration enables nanoscale tracking of synaptic plasticity in living mice. Nature methods (2023)
Sureni H Sumathipala, Suha Khan, Robert A Kozol, Yoichi Araki, Sheyum Syed, Richard L Huganir, Julia E Dallman
Context-dependent hyperactivity in syngap1a and syngap1b zebrafish autism models. bioRxiv : the preprint server for biology (2023)
W Dylan Hale, Thomas C Südhof, Richard L Huganir
Engineered adhesion molecules drive synapse organization. Proceedings of the National Academy of Sciences of the United States of America 120 (3) (2023)
W Dylan Hale, Thomas C Südhof, Richard L Huganir
Engineered adhesion molecules drive synapse organization. Proceedings of the National Academy of Sciences of the United States of America 120 (3) (2023)
Yoichi Araki, Elizabeth E Gerber, Kacey E Rajkovich, Ingie Hong, Richard C Johnson, Hey-Kyoung Lee, Alfredo Kirkwood, Richard L Huganir
Mouse models of SYNGAP1 -related intellectual disability. Proceedings of the National Academy of Sciences of the United States of America 120 (37) (2023)
Yu Kang T Xu, Austin R Graves, Gabrielle I Coste, Richard L Huganir, Dwight E Bergles, Adam S Charles, Jeremias Sulam
Cross-modality supervised image restoration enables nanoscale tracking of synaptic plasticity in living mice. Nature methods (2023)
Jung Ho Hyun, Kenichiro Nagahama, Ho Namkung, Neymi Mignocchi, Seung-Eon Roh, Patrick Hannan, Sarah Kruessel, Chuljung Kwak, Abigail McElroy, Bian Liu, Mingguang Cui, Seunghwan Lee, Dongmin Lee, Richard L Huganir, Paul F Worley, Akira Sawa, Hyung-Bae Kwon
Tagging active neurons by soma-targeted Cal-Light. Nature communications 13 (1) (2022)
Xudong Chen, Bowen Jia, Yoichi Araki, Bian Liu, Fei Ye, Richard L Huganir, Mingjie Zhang
Arc weakens synapses by dispersing AMPA receptors from postsynaptic density via modulating PSD phase separation. Cell research 32 (10) (2022)
Jung Ho Hyun, Kenichiro Nagahama, Ho Namkung, Neymi Mignocchi, Seung-Eon Roh, Patrick Hannan, Sarah Kruessel, Chuljung Kwak, Abigail McElroy, Bian Liu, Mingguang Cui, Seunghwan Lee, Dongmin Lee, Richard L Huganir, Paul F Worley, Akira Sawa, Hyung-Bae Kwon
Tagging active neurons by soma-targeted Cal-Light. Nature communications 13 (1) (2022)
Jung Ho Hyun, Kenichiro Nagahama, Ho Namkung, Neymi Mignocchi, Seung-Eon Roh, Patrick Hannan, Sarah Kruessel, Chuljung Kwak, Abigail McElroy, Bian Liu, Mingguang Cui, Seunghwan Lee, Dongmin Lee, Richard L Huganir, Paul F Worley, Akira Sawa, Hyung-Bae Kwon
Tagging active neurons by soma-targeted Cal-Light. Nature communications 13 (1) (2022)
Jonathan P Ling, Alexei M Bygrave, Clayton P Santiago, Rogger P Carmen-Orozco, Vickie T Trinh, Minzhong Yu, Yini Li, Ying Liu, Kyra D Bowden, Leighton H Duncan, Jeong Han, Kamil Taneja, Rochinelle Dongmo, Travis A Babola, Patrick Parker, Lizhi Jiang, Patrick J Leavey, Jennifer J Smith, Rachel Vistein, Megan Y Gimmen, Benjamin Dubner, Eric Helmenstine, Patric Teodorescu, Theodoros Karantanos, Gabriel Ghiaur, Patrick O Kanold, Dwight E Bergles, Ben Langmead, Shuying Sun, Kristina J Nielsen, Neal S Peachey, Mandeep S Singh, W Brian Dalton, Fatemeh Rajaii, Richard L Huganir, Seth Blackshaw
Cell-specific regulation of gene expression using splicing-dependent frameshifting. Nature communications 13 (1) (2022)
Jung Ho Hyun, Kenichiro Nagahama, Ho Namkung, Neymi Mignocchi, Seung-Eon Roh, Patrick Hannan, Sarah Kruessel, Chuljung Kwak, Abigail McElroy, Bian Liu, Mingguang Cui, Seunghwan Lee, Dongmin Lee, Richard L Huganir, Paul F Worley, Akira Sawa, Hyung-Bae Kwon
Tagging active neurons by soma-targeted Cal-Light. Nature communications 13 (1) (2022)
Jung Ho Hyun, Kenichiro Nagahama, Ho Namkung, Neymi Mignocchi, Seung-Eon Roh, Patrick Hannan, Sarah Kruessel, Chuljung Kwak, Abigail McElroy, Bian Liu, Mingguang Cui, Seunghwan Lee, Dongmin Lee, Richard L Huganir, Paul F Worley, Akira Sawa, Hyung-Bae Kwon
Tagging active neurons by soma-targeted Cal-Light. Nature communications 13 (1) (2022)
Jung Ho Hyun, Kenichiro Nagahama, Ho Namkung, Neymi Mignocchi, Seung-Eon Roh, Patrick Hannan, Sarah Kruessel, Chuljung Kwak, Abigail McElroy, Bian Liu, Mingguang Cui, Seunghwan Lee, Dongmin Lee, Richard L Huganir, Paul F Worley, Akira Sawa, Hyung-Bae Kwon
Tagging active neurons by soma-targeted Cal-Light. Nature communications 13 (1) (2022)
Haiwen Chen, Richard H Roth, Elena Lopez-Ortega, Han L Tan, Richard L Huganir
AMPA Receptors Exist in Tunable Mobile and Immobile Synaptic Fractions In Vivo. eNeuro 8 (3) (2021)
Rebeca Mejias, Juan Jose Rodriguez Gotor, Minae Niwa, Irina N Krasnova, Abby Adamczyk, Mei Han, Gareth M Thomas, Zheng-Xiong Xi, Richard L Huganir, Mikhail V Pletnikov, Akira Sawa, Jean-Lud Cadet, Tao Wang
Increased novelty-induced locomotion, sensitivity to amphetamine, and extracellular dopamine in striatum of Zdhhc15-deficient mice. Translational psychiatry 11 (1) (2021)
Daniel Severin, Su Z Hong, Seung-Eon Roh, Shiyong Huang, Jiechao Zhou, Michelle C D Bridi, Ingie Hong, Sachiko Murase, Sarah Robertson, Rebecca P Haberman, Richard L Huganir, Michela Gallagher, Elizabeth M Quinlan, Paul F Worley, Alfredo Kirkwood
All-or-none disconnection of pyramidal inputs onto parvalbumin-positive interneurons gates ocular dominance plasticity. Proceedings of the National Academy of Sciences of the United States of America 118 (37) (2021)
Austin R Graves, Richard H Roth, Han L Tan, Qianwen Zhu, Alexei M Bygrave, Elena Lopez-Ortega, Ingie Hong, Alina C Spiegel, Richard C Johnson, Joshua T Vogelstein, Daniel J Tward, Michael I Miller, Richard L Huganir
Visualizing synaptic plasticity in vivo by large-scale imaging of endogenous AMPA receptors. eLife 10 (2021)
Madeleine Kyrke-Smith, Lenora J Volk, Samuel F Cooke, Mark F Bear, Richard L Huganir, Jason D Shepherd
The Immediate Early Gene Arc Is Not Required for Hippocampal Long-Term Potentiation. The Journal of neuroscience : the official journal of the Society for Neuroscience 41 (19) (2021)
Huaqiang Fang, Alexei M Bygrave, Richard H Roth, Richard C Johnson, Richard L Huganir
An optimized CRISPR/Cas9 approach for precise genome editing in neurons. eLife 10 (2021)
Jin-Fan Zhang, Bian Liu, Ingie Hong, Albert Mo, Richard H Roth, Brian Tenner, Wei Lin, Jason Z Zhang, Rosana S Molina, Mikhail Drobizhev, Thomas E Hughes, Lin Tian, Richard L Huganir, Sohum Mehta, Jin Zhang
An ultrasensitive biosensor for high-resolution kinase activity imaging in awake mice. Nature chemical biology 17 (1) (2020)
Yoichi Araki, Ingie Hong, Timothy R Gamache, Shaowen Ju, Leonardo Collado-Torres, Joo Heon Shin, Richard L Huganir
SynGAP isoforms differentially regulate synaptic plasticity and dendritic development. eLife 9 (2020)
Caitlin E Burgdorf, Charlotte C Bavley, Delaney K Fischer, Alexander P Walsh, Arlene Martinez-Rivera, Jonathan E Hackett, Lia J Zallar, Kyle E Ireton, Franz Hofmann, Johannes W Hell, Richard L Huganir, Anjali M Rajadhyaksha
Contribution of D1R-expressing neurons of the dorsal dentate gyrus and Cav1.2 channels in extinction of cocaine conditioned place preference. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 45 (9) (2020)
Adeline J H Yong, Han L Tan, Qianwen Zhu, Alexei M Bygrave, Richard C Johnson, Richard L Huganir
Tyrosine phosphorylation of the AMPA receptor subunit GluA2 gates homeostatic synaptic plasticity. Proceedings of the National Academy of Sciences of the United States of America 117 (9) (2020)
Timothy R Gamache, Yoichi Araki, Richard L Huganir
Twenty Years of SynGAP Research: From Synapses to Cognition. The Journal of neuroscience : the official journal of the Society for Neuroscience 40 (8) (2020)
Han L Tan, Richard H Roth, Austin R Graves, Robert H Cudmore, Richard L Huganir
Lamina-specific AMPA receptor dynamics following visual deprivation in vivo. eLife 9 (2020)
Jocelyn Widagdo, Jun Wei Kerk, Sumasri Guntupalli, Richard L Huganir, Victor Anggono
Subunit-Specific Augmentation of AMPA Receptor Ubiquitination by Phorbol Ester. Cellular and molecular neurobiology 40 (7) (2020)
Han L Tan, Shu-Ling Chiu, Qianwen Zhu, Richard L Huganir
GRIP1 regulates synaptic plasticity and learning and memory. Proceedings of the National Academy of Sciences of the United States of America 117 (40) (2020)
Edward Y S Lin, Laura F Silvian, Douglas J Marcotte, Charles C Banos, Flora Jow, Timothy R Chan, Robert M Arduini, Fang Qian, Darren P Baker, Chris Bergeron, Catherine A Hession, Richard L Huganir, Cassandra F Borenstein, Istvan Enyedy, Jinming Zou, Ellen Rohde, Marion Wittmann, Gnanasambandam Kumaravel, Kenneth J Rhodes, Robert H Scannevin, Anthone W Dunah, Kevin M Guckian
Potent PDZ-Domain PICK1 Inhibitors that Modulate Amyloid Beta-Mediated Synaptic Dysfunction. Scientific reports 8 (1) (2018)
Sohum Mehta, Yong Zhang, Richard H Roth, Jin-Fan Zhang, Albert Mo, Brian Tenner, Richard L Huganir, Jin Zhang
Single-fluorophore biosensors for sensitive and multiplexed detection of signalling activities. Nature cell biology 20 (10) (2018)
Qian Song, Hong-Wei Zheng, Xu-Hui Li, Richard L Huganir, Thomas Kuner, Min Zhuo, Chen Tao
Selective Phosphorylation of AMPA Receptor Contributes to the Network of Long-Term Potentiation in the Anterior Cingulate Cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience 37 (35) (2017)
Caitlin E Burgdorf, Kathryn C Schierberl, Anni S Lee, Delaney K Fischer, Tracey A Van Kempen, Vladimir Mudragel, Richard L Huganir, Teresa A Milner, Michael J Glass, Anjali M Rajadhyaksha
Extinction of Contextual Cocaine Memories Requires Cav1.2 within D1R-Expressing Cells and Recruits Hippocampal Cav1.2-Dependent Signaling Mechanisms. The Journal of neuroscience : the official journal of the Society for Neuroscience 37 (49) (2017)

Richard L Huganir.css-eqlu8i{font-size:small;padding-left:4px;} (Richard Huganir)

Publication Activity (10 Years)

Top Topics

Top Venues

Richard L Huganir (Richard Huganir)