Zheng-Yu Jiang (Zhengyu Jiang)

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 25

Top Topics

Oxidative Stress

Ischemia Reperfusion Injury

Top Venues

Journal of medicinal chemistry

Expert opinion on therapeutic patents

Oxidative medicine and cellular longevity

Antioxidants (Basel, Switzerland)

This page only lists publications with an associated author ORCID identifier.

Publications

Jian'ai Ji, Yuhui Jin, Sinan Ma, Yuxuan Zhu, Xinyu Bi, Qi-Dong You, Zheng-Yu Jiang
Discovery of a NCOA4 Degrader for Labile Iron-Dependent Ferroptosis Inhibition. Journal of medicinal chemistry 67 (15) (2024)
Jian'ai Ji, Yuhui Jin, Sinan Ma, Yuxuan Zhu, Xinyu Bi, Qi-Dong You, Zheng-Yu Jiang
Discovery of a NCOA4 Degrader for Labile Iron-Dependent Ferroptosis Inhibition. Journal of medicinal chemistry (2024)
Jian'ai Ji, Yuhui Jin, Sinan Ma, Yuxuan Zhu, Xinyu Bi, Qi-Dong You, Zheng-Yu Jiang
Discovery of a NCOA4 Degrader for Labile Iron-Dependent Ferroptosis Inhibition. Journal of medicinal chemistry 67 (15) (2024)
Xian Zhang, Keni Cui, Xiaolu Wang, Yuanyuan Tong, Chihong Liu, Yuechao Zhu, Qi-Dong You, Zheng-Yu Jiang, Xiaoke Guo
Novel Hydrogen Sulfide Hybrid Derivatives of Keap1-Nrf2 Protein-Protein Interaction Inhibitor Alleviate Inflammation and Oxidative Stress in Acute Experimental Colitis. Antioxidants (Basel, Switzerland) 12 (5) (2023)
Ziquan Zhao, Ruitian Dong, Keni Cui, Qidong You, Zheng-Yu Jiang
An updated patent review of Nrf2 activators (2020-present). Expert opinion on therapeutic patents (2023)
Nan-Nan Chen, Han Zhang, Qiang-Sheng Zhu, Ting Zeng, Wei Dai, Ye-Ling Zhou, Guo-Feng Xin, Bei-Duo Wu, Si-Jia Gong, Zheng-Yu Jiang, Qi-Dong You, Xiao-Li Xu
Development of Orally Bioavailable Amidobenzimidazole Analogues Targeting Stimulator of Interferon Gene (STING) Receptor. Journal of medicinal chemistry (2023)
Ziquan Zhao, Ruitian Dong, Keni Cui, Qidong You, Zheng-Yu Jiang
An updated patent review of Nrf2 activators (2020-present). Expert opinion on therapeutic patents 33 (1) (2023)
Yuhui Jin, Jing Fan, Ruyan Wang, Xuanyu Wang, Ning Li, Qi-Dong You, Zheng-Yu Jiang
Ligation to Scavenging Strategy Enables On-Demand Termination of Targeted Protein Degradation. Journal of the American Chemical Society (2023)
Ziquan Zhao, Ruitian Dong, Keni Cui, Qidong You, Zheng-Yu Jiang
An updated patent review of Nrf2 activators (2020-present). Expert opinion on therapeutic patents 33 (1) (2023)
Jianai Ji, Sinan Ma, Yuxuan Zhu, Jinglong Zhao, Yuanyuan Tong, Qi-Dong You, Zheng-Yu Jiang
ARE-PROTACs Enable Co-degradation of an Nrf2-MafG Heterodimer. Journal of medicinal chemistry (2023)
Xuetao Chen, Danyan Cao, Chihong Liu, Fanying Meng, Zijian Zhang, Rujun Xu, Yuanyuan Tong, Yabing Xin, Weikun Zhang, Wenjing Kang, Qichao Bao, Jingkang Shen, Bing Xiong, Qi-Dong You, Zheng-Yu Jiang
Discovery of 1 H -Imidazo[4,5- b ]pyridine Derivatives as Potent and Selective BET Inhibitors for the Management of Neuropathic Pain. Journal of medicinal chemistry (2023)
Ying-Zhe Wang, Hong-Yu Li, Yan Zhang, Rui-Xin Jiang, Jun Xu, Jing Gu, Zheng Jiang, Zheng-Yu Jiang, Qi-Dong You, Xiao-Ke Guo
Discovery of Pyrazolo[1,5- a ]pyrimidine Derivative as a Novel and Selective ALKBH5 Inhibitor for the Treatment of AML. Journal of medicinal chemistry (2023)
Ziquan Zhao, Ruitian Dong, Qi-Dong You, Zheng-Yu Jiang
Medicinal Chemistry Insights into the Development of Small-Molecule Kelch-Like ECH-Associated Protein 1-Nuclear Factor Erythroid 2-Related Factor 2 (Keap1-Nrf2) Protein-Protein Interaction Inhibitors. Journal of medicinal chemistry (2023)
Yi Mou, Shuai Wen, Xinxing Gao, Zheng-Yu Jiang
Proteolysis-targeting chimeras: a kaleidoscope of targeted protein degradation. Future medicinal chemistry (2021)
Weilin Chen, Xin Chen, Dongdong Li, Jianrui Zhou, Zheng-Yu Jiang, Qi-Dong You, Xiao-Ke Guo
Discovery of DDO-2213 as a Potent and Orally Bioavailable Inhibitor of the WDR5-Mixed Lineage Leukemia 1 Protein-Protein Interaction for the Treatment of MLL Fusion Leukemia. Journal of medicinal chemistry 64 (12) (2021)
Peng-Ju Zhu, Ze-Zhou Yu, Yi-Fei Lv, Jing-Long Zhao, Yuan-Yuan Tong, Qi-Dong You, Zheng-Yu Jiang
Discovery of 3,5-Dimethyl-4-Sulfonyl-1H-Pyrrole-Based Myeloid Cell Leukemia 1 Inhibitors with High Affinity, Selectivity, and Oral Bioavailability. Journal of medicinal chemistry 64 (15) (2021)
Hai-Shan Zhou, Lv-Bin Hu, Han Zhang, Wen-Xin Shan, Yan Wang, Xue Li, Tian Liu, Jing Zhao, Qi-Dong You, Zheng-Yu Jiang
Design, Synthesis, and Structure-Activity Relationships of Indoline-Based Kelch-like ECH-Associated Protein 1-Nuclear Factor (Erythroid-Derived 2)-Like 2 (Keap1-Nrf2) Protein-Protein Interaction Inhibitors. Journal of medicinal chemistry 63 (19) (2020)
Haishan Zhou, Yan Wang, Qidong You, Zheng-Yu Jiang
Recent progress in the development of small molecule Nrf2 activators: a patent review (2017-present). Expert opinion on therapeutic patents 30 (3) (2020)
Yu-Hui Jin, Meng-Chen Lu, Yan Wang, Wen-Xin Shan, Xuan-Yu Wang, Qi-Dong You, Zheng-Yu Jiang
Azo-PROTAC: Novel Light-Controlled Small-Molecule Tool for Protein Knockdown. Journal of medicinal chemistry 63 (9) (2020)
Meng-Chen Lu, Xian Zhang, Feng Wu, Shi-Jie Tan, Jing Zhao, Qi-Dong You, Zheng-Yu Jiang
Discovery of a Potent Kelch-Like ECH-Associated Protein 1-Nuclear Factor Erythroid 2-Related Factor 2 (Keap1-Nrf2) Protein-Protein Interaction Inhibitor with Natural Proline Structure as a Cytoprotective Agent against Acetaminophen-Induced Hepatotoxicity. Journal of medicinal chemistry 62 (14) (2019)
Lei Wang, Lixiao Zhang, Li Li, Jingsheng Jiang, Zhen Zheng, Jialin Shang, Chengxiang Wang, Weilin Chen, Qichao Bao, Xiao-Li Xu, Zheng-Yu Jiang, Jian Zhang, Qi-Dong You
Small-molecule inhibitor targeting the Hsp90-Cdc37 protein-protein interaction in colorectal cancer. Science advances 5 (9) (2019)
Li-Li Xu, Tian Liu, Lei Wang, Li Li, Yu-Feng Wu, Cui-Cui Li, Bin Di, Qi-Dong You, Zheng-Yu Jiang
3-(1H-Benzo[d]imidazol-6-yl)-5-(4-fluorophenyl)-1,2,4-oxadiazole (DDO7232), a Novel Potent Nrf2/ARE Inducer, Ameliorates DSS-Induced Murine Colitis and Protects NCM460 Cells against Oxidative Stress via ERK1/2 Phosphorylation. Oxidative medicine and cellular longevity 2018 (2018)
Zheng-Yu Jiang, Meng-Chen Lu, Qi-Dong You
Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) Inhibition: An Emerging Strategy in Cancer Therapy. Journal of medicinal chemistry 62 (8) (2018)
Li-Li Xu, Tian Liu, Lei Wang, Li Li, Yu-Feng Wu, Cui-Cui Li, Bin Di, Qi-Dong You, Zheng-Yu Jiang
Corrigendum to "3-(1H-Benzo[d]imidazol-6-yl)-5-(4-fluorophenyl)-1, 2, 4-oxadiazole (DDO7232), a Novel Potent Nrf2/ARE Inducer, Ameliorates DSS-Induced Murine Colitis and Protects NCM460 Cells against Oxidative Stress via ERK1/2 Phosphorylation". Oxidative medicine and cellular longevity 2018 (2018)
Hongbin Dai, Qiong Jiao, Tian Liu, Qidong You, Zheng-Yu Jiang
Development of Novel Nrf2/ARE Inducers Bearing Pyrazino[2,1-a]isoquinolin Scaffold with Potent In Vitro Efficacy and Enhanced Physicochemical Properties. Molecules (Basel, Switzerland) 22 (9) (2017)