Lei Wang

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 28

Top Topics

Tyrosine Kinase

Top Venues

Journal of medicinal chemistry

Expert opinion on therapeutic patents

Journal of the American Chemical Society

Future medicinal chemistry

This page only lists publications with an associated author ORCID identifier.

Publications

Qiuyue Zhang, Ling Yan, Lixiao Zhang, Jia Yu, Zeyu Han, Hua Liu, Jinying Gu, Keran Wang, Jiayi Wang, Fangsu Chen, Rongde Zhao, Yang Yan, Cheng Jiang, Qi-Dong You, Lei Wang
Allosteric Activation of Protein Phosphatase 5 with Small Molecules. Journal of medicinal chemistry (2024)
Qiuyue Zhang, Ling Yan, Yuxuan Zhang, Lixiao Zhang, Jia Yu, Qi-Dong You, Lei Wang
Rational design of peptide inhibitors targeting HSP90-CDC37 protein-protein interaction. Future medicinal chemistry 16 (2) (2024)
Jianfeng Liu, Huangliang Shu, Qinxin Xia, Qi-Dong You, Lei Wang
Recent developments of HSP90 inhibitors: an updated patent review (2020-present). Expert opinion on therapeutic patents 34 (1-2) (2024)
Zekun Li, Mochen Guo, Mingxiao Gu, Zhongtian Cai, Qiuyu Wu, Jia Yu, Meilun Tang, Chenxi He, Yuxuan Wang, Piaoyang Sun, Qi-Dong You, Lei Wang
Design and Synthesis of 7-Oxabicyclo[2.2.1]heptane-2,3-dicarboxylic Acid Derivatives as PP5 Inhibitors To Reverse Temozolomide Resistance in Glioblastoma Multiforme. Journal of medicinal chemistry (2024)
Jianfeng Liu, Huangliang Shu, Qinxin Xia, Qi-Dong You, Lei Wang
Recent developments of HSP90 inhibitors: an updated patent review (2020-present). Expert opinion on therapeutic patents (2024)
Jianfeng Liu, Huangliang Shu, Qinxin Xia, Qi-Dong You, Lei Wang
Recent developments of HSP90 inhibitors: an updated patent review (2020-present). Expert opinion on therapeutic patents 34 (1-2) (2024)
Qiuyue Zhang, Ling Yan, Yuxuan Zhang, Lixiao Zhang, Jia Yu, Qi-Dong You, Lei Wang
Rational design of peptide inhibitors targeting HSP90-CDC37 protein-protein interaction. Future medicinal chemistry 16 (2) (2024)
Jianfeng Liu, Huangliang Shu, Qinxin Xia, Qi-Dong You, Lei Wang
Recent developments of HSP90 inhibitors: an updated patent review (2020-present). Expert opinion on therapeutic patents (2024)
Qiuyue Zhang, Ling Yan, Yuxuan Zhang, Lixiao Zhang, Jia Yu, Qi-Dong You, Lei Wang
Rational design of peptide inhibitors targeting HSP90-CDC37 protein-protein interaction. Future medicinal chemistry 16 (2) (2024)
Qiuyue Zhang, Ling Yan, Yuxuan Zhang, Lixiao Zhang, Jia Yu, Qi-Dong You, Lei Wang
Rational design of peptide inhibitors targeting HSP90-CDC37 protein-protein interaction. Future medicinal chemistry (2024)
Jianfeng Liu, Huangliang Shu, Qinxin Xia, Qi-Dong You, Lei Wang
Recent developments of HSP90 inhibitors: an updated patent review (2020-present). Expert opinion on therapeutic patents 34 (1-2) (2024)
Mingxiao Gu, Sudan Sun, Qi-Dong You, Lei Wang
Forward or Backward: Lessons Learned from Small Molecule Drugs Approved by FDA from 2012 to 2022. Molecules (Basel, Switzerland) 28 (24) (2023)
Liwen Hua, Danni Wang, Keran Wang, Yuxuan Wang, Jinying Gu, Qiuyue Zhang, Qi-Dong You, Lei Wang
Design of Tracers in Fluorescence Polarization Assay for Extensive Application in Small Molecule Drug Discovery. Journal of medicinal chemistry (2023)
Mingxiao Gu, Sudan Sun, Qi-Dong You, Lei Wang
Forward or Backward: Lessons Learned from Small Molecule Drugs Approved by FDA from 2012 to 2022. Molecules (Basel, Switzerland) 28 (24) (2023)
Xuexuan Wu, Qiuyue Zhang, Yuqi Guo, Hengheng Zhang, Xiaoke Guo, Qi-Dong You, Lei Wang
Methods for the Discovery and Identification of Small Molecules Targeting Oxidative Stress-Related Protein-Protein Interactions: An Update. Antioxidants (Basel, Switzerland) 11 (4) (2022)
Liwen Hua, Qiuyue Zhang, Xinyue Zhu, Ruoning Wang, Qi-Dong You, Lei Wang
Beyond Proteolysis-Targeting Chimeric Molecules: Designing Heterobifunctional Molecules Based on Functional Effectors. Journal of medicinal chemistry 65 (12) (2022)
Wei Liu, Jingsheng Jiang, Yating Lin, Qi-Dong You, Lei Wang
Insight into Thermodynamic and Kinetic Profiles in Small-Molecule Optimization. Journal of medicinal chemistry 65 (16) (2022)
Qiuyue Zhang, Xuexuan Wu, Hengheng Zhang, Qiuyu Wu, Min Fu, Liwen Hua, Xinyue Zhu, Yuqi Guo, Lianshan Zhang, Qi-Dong You, Lei Wang
Protein Phosphatase 5-Recruiting Chimeras for Accelerating Apoptosis-Signal-Regulated Kinase 1 Dephosphorylation with Antiproliferative Activity. Journal of the American Chemical Society (2022)
Qiuyue Zhang, Xuexuan Wu, Hengheng Zhang, Qiuyu Wu, Min Fu, Liwen Hua, Xinyue Zhu, Yuqi Guo, Lianshan Zhang, Qi-Dong You, Lei Wang
Protein Phosphatase 5-Recruiting Chimeras for Accelerating Apoptosis-Signal-Regulated Kinase 1 Dephosphorylation with Antiproliferative Activity. Journal of the American Chemical Society 145 (2) (2022)
Qiuyue Zhang, Xuexuan Wu, Hengheng Zhang, Qiuyu Wu, Min Fu, Liwen Hua, Xinyue Zhu, Yuqi Guo, Lianshan Zhang, Qi-Dong You, Lei Wang
Protein Phosphatase 5-Recruiting Chimeras for Accelerating Apoptosis-Signal-Regulated Kinase 1 Dephosphorylation with Antiproliferative Activity. Journal of the American Chemical Society 145 (2) (2022)
Qiuyue Zhang, Xuexuan Wu, Hengheng Zhang, Qiuyu Wu, Min Fu, Liwen Hua, Xinyue Zhu, Yuqi Guo, Lianshan Zhang, Qi-Dong You, Lei Wang
Protein Phosphatase 5-Recruiting Chimeras for Accelerating Apoptosis-Signal-Regulated Kinase 1 Dephosphorylation with Antiproliferative Activity. Journal of the American Chemical Society 145 (2) (2022)
Changyou Ma, Jian Wu, Lei Wang, Xiaojun Ji, Yebin Wu, Lei Miao, Donghui Chen, Linlin Zhang, Youzhi Wu, Haiwei Feng, Ying Tang, Qiuhua Zhou, Junjie Pei, Xule Yang, Dan Xu, Qi-Dong You, Yuan Xie
Discovery of Clinical Candidate NTQ1062 as a Potent and Bioavailable Akt Inhibitor for the Treatment of Human Tumors. Journal of medicinal chemistry 65 (12) (2022)
Qiuyue Zhang, Xuexuan Wu, Hengheng Zhang, Qiuyu Wu, Min Fu, Liwen Hua, Xinyue Zhu, Yuqi Guo, Lianshan Zhang, Qi-Dong You, Lei Wang
Protein Phosphatase 5-Recruiting Chimeras for Accelerating Apoptosis-Signal-Regulated Kinase 1 Dephosphorylation with Antiproliferative Activity. Journal of the American Chemical Society 145 (2) (2022)
Qiuyue Zhang, Zhongjiao Fan, Lianshan Zhang, Qi-Dong You, Lei Wang
Strategies for Targeting Serine/Threonine Protein Phosphatases with Small Molecules in Cancer. Journal of medicinal chemistry 64 (13) (2021)
Lei Wang, Qiuyue Zhang, Qi-Dong You
Targeting the HSP90-CDC37-kinase chaperone cycle: A promising therapeutic strategy for cancer. Medicinal research reviews 42 (1) (2021)
Lei Wang, Jingsheng Jiang, Lixiao Zhang, Qiuyue Zhang, Jianrui Zhou, Li Li, Xiao-Li Xu, Qi-Dong You
Discovery and Optimization of Small Molecules Targeting the Protein-Protein Interaction of Heat Shock Protein 90 (Hsp90) and Cell Division Cycle 37 as Orally Active Inhibitors for the Treatment of Colorectal Cancer. Journal of medicinal chemistry 63 (3) (2020)
Lei Wang, Lixiao Zhang, Li Li, Jingsheng Jiang, Zhen Zheng, Jialin Shang, Chengxiang Wang, Weilin Chen, Qichao Bao, Xiao-Li Xu, Zheng-Yu Jiang, Jian Zhang, Qi-Dong You
Small-molecule inhibitor targeting the Hsp90-Cdc37 protein-protein interaction in colorectal cancer. Science advances 5 (9) (2019)
Li Li, Lei Wang, Qi-Dong You, Xiao-Li Xu
Heat Shock Protein 90 Inhibitors: An Update on Achievements, Challenges, and Future Directions. Journal of medicinal chemistry 63 (5) (2019)