CCN4/WISP1 Promotes Migration of Human Primary Osteoarthritic Chondrocytes.
Ritchie G M TimmermansArjen B BlomNiek G C BloksRob G H H NelissenEnrike H M J van der LindenPeter M van der KraanIngrid MeulenbeltYolande Y F M RamosMartijn H J van den BoschPublished in: Cartilage (2022)
CCN4 increases cell migration of human primary OA chondrocytes. Since WISP1 expression is known to be increased in OA cartilage, this may serve to direct chondrocytes toward cartilage defects and orchestrate repair.