Effect of long-acting β-agonists/glucocorticoids on human airway epithelial cell cytokine, transcriptomic and oxidative stress responses to cannabis smoke.

Ryan D HuffJennifer A AguiarWayne TseMartin R StämpfliBrendan J McConkeyAndrew C DoxeyJeremy A Hirota

Published in: ERJ open research (2020)

LABA/GC intervention in airway epithelial cells exposed to cannabis smoke reduces levels of pro-inflammatory (CXCL8) and antiviral (CXCL10) mediators, while transcriptomic signatures of neutrophil-mediated immunity and oxidative stress remain elevated http://bit.ly/2qiSQhH.

Keyphrases

oxidative stress
single cell
endothelial cells
dna damage
rna seq
randomized controlled trial
diabetic rats
induced apoptosis
induced pluripotent stem cells
genome wide
pluripotent stem cells
gene expression
mass spectrometry
heat shock
signaling pathway
gas chromatography