Metformin does not affect postabsorptive hepatic free fatty acid uptake, oxidation or resecretion in humans: A 3-month placebo-controlled clinical trial in patients with type 2 diabetes and healthy controls.

Lars Christian GormsenEsben SøndergaardNana L ChristensenSteen JakobsenErik H T NielsenOle L MunkLars P TolbodNiels JessenSøren Nielsen

Published in: Diabetes, obesity & metabolism (2018)

The observed beneficial effects on lipid metabolism during metformin treatment in humans appear to be secondary to long-term alterations in body composition or glucose homeostasis.

Keyphrases

body composition
fatty acid
clinical trial
double blind
resistance training
placebo controlled
bone mineral density
phase ii
study protocol
phase iii
open label
randomized controlled trial
blood glucose
radiation therapy
postmenopausal women