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The Effect of Adjuvant Radiotherapy on One- and Two-Stage Prosthetic Breast Reconstruction and on Autologous Reconstruction: A Multicenter Italian Study among 18 Senonetwork Breast Centres.

Andrea Vittorio Emanuele LisaMarzia SalgarelloAlessandra HuscherFabio CorsiDaniele PiovaniFederica RubbinoStefania AndreolettiGiovanni PapaFrancesco KlingerCorrado TinterriAlberto TestoriMarta ScorsettiPaolo VeronesiMaria Cristina LeonardiMario RietjensUmberto CortinovisValeria SummoEmanuele Rampino CordaroPier Camillo ParodiPaolo PersichettiMauro BaroneGiorgio De SantisMatteo MuroloMichele RiccioAngelica AquinatiFrancesco CavaliereNicola VaiaGiulia PaguraErica Dalla VeneziaFranco BassettoVincenzo VindigniLuigi CiuffredaMaria Alessandra BocchiottiAlberto SciarilloNadia RenziGraziano MeneghiniTajna KraljicAndrea LoretiLucio FortunatoValentina PinoValeriano VinciKlinger Marco
Published in: The breast journal (2023)
Our study confirms that autologous reconstruction is the procedure least impacted by PMRT, while DTI appears to be the most impacted by PMRT, when compared with TE/I which shows a lower rate of explant and reconstruction failure. The trial is registered with NCT04783818, and the date of registration is 1 March, 2021, retrospectively registered.
Keyphrases
  • early stage
  • clinical trial
  • randomized controlled trial
  • bone marrow
  • radiation therapy
  • cell therapy
  • study protocol
  • squamous cell carcinoma
  • cross sectional
  • double blind